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Results: 69
Detecting and comparing non-coding RNAs in the high-throughput era.
In recent years there has been a growing interest in the field of non-coding RNA. This surge is a direct consequence of the discovery of a huge number of new non-coding genes and of the finding that many of these transcripts are...
Mapping the biogenesis of forward programmed megakaryocytes from induced pluripotent stem cells
Cedric Ghevaert
Mar 19, 2022
Platelet deficiency, known as thrombocytopenia, can cause haemorrhage and is treated with
platelet transfusions. We developed a system for the production of platelet precursor cells,
megakaryocytes, from pluripotent stem...
Winthrop Freshmen to Read Common Book, ''A Hope in the Unseen''
Winthrop University
Jan 01, 0001
This year's selection is Ron Suskind's book "A Hope in the Unseen" about Cedric Jennings' struggle to get out of one of the worst public high schools in Washington, D.C. and to attend Brown University. Virginia Williams...
Published by: Winthrop University
Optimal Favoritism in All-Pay Auctions and Lottery Contests
We analyze the revenue-enhancing potential of favoring specific contestants in complete-information all-pay auctions and lottery contests with several heterogeneous contestants. Two instruments of favoritism are considered: head...
Heat Capacity of Drained Peat Soils
Soil-specific heat capacity (cp) and volumetric heat capacity (Cv) are recognized as a fundamental soil property essential for the accurate prediction of soil temperature and heat flow. This study presents the analysis...
Tomasz Gnatowski, Ewa Ostrowska-Ligęza, Cedric Kechavarzi, Grzegorz Kurzawski, Jan Szatyłowicz
Feb 02, 2022
Optimal Favoritism in All-Pay Auctions and Lottery Contests
We analyze the revenue-enhancing potential of favoring specific contestants in complete-information all-pay auctions and lottery contests with several heterogeneous contestants. Two instruments of favoritism are considered: head...
Integrity Testing of Pile Cover Using Distributed Fibre Optic Sensing.
The integrity of cast-in-place foundation piles is a major concern in geotechnical engineering. In this study, distributed fibre optic sensing (DFOS) cables, embedded in a pile during concreting, are used to measure the changes...
Temperature and Humidity Stability of Fibre Optic Sensor Cables for High Resolution Measurements
Fibre optic sensors offer a means for the real-time continuous measurement of temperature or strain in concrete structures. Backscattered light along a fibre optic sensing (FOS) cable is interrogated to record a...
Monitoring the Hydraulic Performance of Sewers Using Fibre Optic Distributed Temperature Sensing
The hydraulic performance of sewers is a major public concern in industrialised countries. In this study, fibre optic distributed temperature sensing (DTS) is used to monitor the discharge of wastewater for three months to...
A Mathematical Model of a Valve-Controlled Bioreactor for Platelet Production
As blood donor numbers decrease, while demand for platelets increases, hospitals worldwide are becoming increasingly vulnerable to critical platelet shortages. Alternative methods of supplying platelets are therefore...
Distributed fibre-optic monitoring of an Osterberg-cell pile test in London
Loizos Pelecanos, Kenichi Soga, Musa P.M. Chunge, Yue Ouyang, Vivien Kwan, Cedric Kechavarzi, Duncan Nicholson
Jun 01, 2017
This paper presents a case study of an Osterberg-cell test of a pile located at the Isle of Dogs in London, which was heavily instrumented with distributed optical-fibre sensors, strain gauges, displacement transducers and...
Process analysis of pluripotent stem cell differentiation to megakaryocytes to make platelets applying European GMP.
Moyra Lawrence, Amanda Evans, Thomas Moreau, Marta Bagnati, Matthew Smart, Enas Hassan, Jahid Hasan, Monica Pianella, Julie Kerby, Cedric Ghevaert
Jun 27, 2021
Quality, traceability and reproducibility are crucial factors in the reliable manufacture of cellular therapeutics, as part of the overall framework of Good Manufacturing Practice (GMP). As more and more cellular therapeutics...
Published by: NPJ Regenerative medicine
Distributed fiber optic monitoring of a CFA pile with a central reinforcement bar bundle
Abstract: In this paper, we present an application of distributed fiber optic sensor (DFOS) technology to measure the strain of a continuous flight auger (CFA) test pile with a central reinforcement bar bundle, during a static...
Distributed fiber optic sensing of axially loaded bored piles
Loizos Pelecanos, Kenichi Soga, Mohammed Elshafie, Nicholas de Battista, Cedric Kechavarzi, Chang Ye Gue, Yue Ouyang, Hyungjoon Seo
Mar 31, 2018
Instrumented pile tests are vital to establish the performance of a pile and validate the assumptions made during initial design. Conventional instrumentation includes vibrating wire strain gauges and extensometers to measure...
The placenta protects the fetal circulation from anxiety-driven elevations in maternal serum levels of brain-derived neurotrophic factor.
Hayley Dingsdale, Xinsheng Nan, Samantha M Garay, Annett Mueller, Lorna A Sumption, Pedro Chacón-Fernández, Isabel Martinez-Garay, Cedric Ghevaert, Yves-Alain Barde, Rosalind M John
Feb 19, 2021
Brain-derived neurotrophic factor (BDNF) plays crucial roles in brain function. Numerous studies report alterations in BDNF levels in human serum in various neurological conditions, including mood disorders such as depression....
Inhibition of interleukin-1β reduces myelofibrosis and osteosclerosis in mice with JAK2-V617F driven myeloproliferative neoplasm.
Shivam Rai, Elodie Grockowiak, Nils Hansen, Damien Luque Paz, Cedric B Stoll, Hui Hao-Shen, Gabriele Mild-Schneider, Stefan Dirnhofer, Christopher J Farady, Simón Méndez-Ferrer, Radek C Skoda
Sep 13, 2022
Interleukin-1β (IL-1β) is a master regulator of inflammation. Increased activity of IL-1β has been implicated in various pathological conditions including myeloproliferative neoplasms (MPNs). Here we show that IL-1β serum levels...
An intrinsically disordered proteins community for ELIXIR.
Norman E Davey, M Madan Babu, Martin Blackledge, Alan Bridge, Salvador Capella-Gutierrez, Zsuzsanna Dosztanyi, Rachel Drysdale, Richard J Edwards, Arne Elofsson, Isabella C Felli, Toby J Gibson, Aleksandras Gutmanas, John M Hancock, Jen Harrow, Desmond Higgins, Cy M Jeffries, Philippe Le Mercier, Balint Mészáros, Marco Necci, Cedric Notredame, Sandra Orchard, Christos A Ouzounis, Rita Pancsa, Elena Papaleo, Roberta Pierattelli, Damiano Piovesan, Vasilis J Promponas, Patrick Ruch, Gabriella Rustici, Pedro Romero, Sirarat Sarntivijai, Gary Saunders, Benjamin Schuler, Malvika Sharan, Denis C Shields, Joel L Sussman, Jonathan A Tedds, Peter Tompa, Michael Turewicz, Jiri Vondrasek, Wim F Vranken, Bonnie Ann Wallace, Kanin Wichapong, Silvio CE Tosatto
Jan 12, 2020
Intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs) are now recognised as major determinants in cellular regulation. This white paper presents a roadmap for future e-infrastructure developments...
Exclusive multipotency and preferential asymmetric divisions in post-embryonic neural stem cells of the fish retina.
Inhibition of interleukin-1β reduces myelofibrosis and osteosclerosis in mice with JAK2-V617F driven myeloproliferative neoplasm.
Shivam Rai, Elodie Grockowiak, Nils Hansen, Damien Luque Paz, Cedric B Stoll, Hui Hao-Shen, Gabriele Mild-Schneider, Stefan Dirnhofer, Christopher J Farady, Simón Méndez-Ferrer, Radek C Skoda
Oct 15, 2022
Interleukin-1β (IL-1β) is a master regulator of inflammation. Increased activity of IL-1β has been implicated in various pathological conditions including myeloproliferative neoplasms (MPNs). Here we show that IL-1β serum levels...
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