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Results: 94
Effect of filgotinib on health-related quality of life in active psoriatic arthritis
Ana-Maria Orbai, Alexis Ogdie, Laure Gossec, William Tillett, Ying Ying Leung, Jingjing Gao, Mona Trivedi, Chantal Tasset, Luc Meuleners, Robin Besuyen, Thijs Hendrikx, Laura C Coates
Jul 01, 2020
To examine the effects of filgotinib, an oral, selective Janus kinase 1 inhibitor, on health-related quality of life (HRQoL) using the Psoriatic Arthritis Impact of Disease (PsAID)9 questionnaire in active PsA. Methods...
Effect of filgotinib on health-related quality of life in active psoriatic arthritis
Ana-Maria Orbai, Alexis Ogdie, Laure Gossec, William Tillett, Ying Ying Leung, Jingjing Gao, Mona Trivedi, Chantal Tasset, Luc Meuleners, Robin Besuyen, Thijs Hendrikx, Laura C Coates
Jul 01, 2020
To examine the effects of filgotinib, an oral, selective Janus kinase 1 inhibitor, on health-related quality of life (HRQoL) using the Psoriatic Arthritis Impact of Disease (PsAID)9 questionnaire in active PsA. Methods...
The Role of Telework in Resilience During the COVID-19 Pandemic
Chantal Fuhrer
Apr 28, 2023
The aim of this article is to better understand the role of telework in resilience during the pandemic. The authors analyze the results from five online surveys from March 2020 to February 2021. The corpus results from the...
Published by: IGI Global Scientific Publishing
Prostate cancer in South Africa
Prostate cancer is one of the most common male cancers globally; however little is known about prostate cancer in Africa. Incidence data for prostate cancer in South Africa (SA) from the pathology based National Cancer Registry...
Differing Perceptions of the Smartwatch by Users Within Developed Countries
This article aims to identify differences in the impact of Self-connectivity and the variables of the technological acceptance model (TAM) on smartwatch adoption in developed countries. The countries involved in the data...
Published by: IGI Global Scientific Publishing
Understanding Restaurant Clients' Intention to Use Mobile Applications
Smartphones have changed consumer behavior by providing new mobile technology applications. In order to understand the intention to use mobile applications, this study highlights the factors of usability, loyalty, and trust...
Published by: IGI Global Scientific Publishing
Understanding polygenic models, their development and the potential application of polygenic scores in healthcare.
The use of genomic information to better understand and prevent common complex diseases has been an ongoing goal of genetic research. Over the past few years, research in this area has proliferated with several proposed methods...
Stroke survivors and their families receive information and support on an individual basis from an online forum
Using multiple short epochs optimises the stability of infant EEG connectivity parameters.
Atypicalities in connectivity between brain regions have been implicated in a range of neurocognitive disorders. We require metrics to assess stable individual differences in connectivity in the developing brain, while facing...
Barriers and facilitators to staying in work after stroke
OCCUPATIONAL & INDUSTRIAL MEDICINE PRIMARY CARE qualitative research Adaptation Psychological Adult Aged employment Female Humans Internet Ischemic Attack Transient Male Middle Aged qualitative research Return to Work social support Stroke Rehabilitation Surveys and Questionnaires Survivors workplace Young Adult
The effects of aging and maternal protein restriction during lactation on thymic involution and peripheral immunosenescence in adult mice.
Gerotarget developmental programming immunosenescence lifespan maternal diet thymic involution aging Animal Nutritional Physiological Phenomena Animals Blotting Western Cells Cultured Diet Protein-Restricted Female Flow Cytometry Fluorescent Antibody Technique Immunosenescence Lactation Mice Mice Inbred C57BL RNA Messenger Real-Time Polymerase Chain Reaction Reverse Transcriptase Polymerase Chain Reaction T-Lymphocytes Thymus Gland
HIV testing and burden of HIV infection in black cancer patients in Johannesburg, South Africa
BACKGROUND: HIV infection is a known risk factor for cancer but little is known about HIV testing patterns and the burden of HIV infection in cancer patients. We did a cross-sectional analysis to identify predictors of prior HIV...
How can we address the uncertainties regarding the potential clinical utility of polygenic score-based tests?
Sowmiya Moorthie, Alison Hall, Chantal Babb de Villiers, Joanna Janus, Tanya Brigden, Laura Blackburn, Mark Kroese
Apr 26, 2022
As common low penetrance variants associated with diseases are uncovered, attempts continue to be made to harness this knowledge for improving healthcare. Polygenic scores have been developed as the mechanism by which knowledge...
Using multiple short epochs optimises the stability of infant EEG connectivity parameters
Rianne Haartsen, Bauke van der Velde, Emily J. H. Jones, Mark H. Johnson, Chantal Kemner
Jul 29, 2020
Abstract: Atypicalities in connectivity between brain regions have been implicated in a range of neurocognitive disorders. We require metrics to assess stable individual differences in connectivity in the developing brain, while...
Clinical outcomes in pediatric intestinal failure
Aureliane Chantal Stania Pierret, James Thomas Wilkinson, Matthias Zilbauer, Jake Peter Mann
May 09, 2019
How can we address the uncertainties regarding the potential clinical utility of polygenic score-based tests?
Sowmiya Moorthie, Alison Hall, Chantal Babb de Villiers, Joanna Janus, Tanya Brigden, Laura Blackburn, Mark Kroese
Mar 15, 2022
As common low penetrance variants associated with diseases are uncovered, attempts continue to be made to harness this knowledge for improving healthcare. Polygenic scores have been developed as the mechanism by which knowledge...
Analysis of risk factors associated with hepatocellular carcinoma in black South Africans
OBJECTIVE: The aims of this study were to determine the prevalence of risk factors associated with hepatocellular carcinoma (HCC) in black adult South Africans and to estimate the size of the associated risks. METHODS: A...
Asymmetric chromatin retention and nuclear envelopes separate chromosomes in fused cells in vivo.
Bharath Sunchu, Nicole MynYi Lee, Jennifer A Taylor, Roberto Carlos Segura, Chantal Roubinet, Clemens Cabernard
Oct 24, 2022
Hybrid cells derived through fertilization or somatic cell fusion recognize and separate chromosomes of different origins. The underlying mechanisms are unknown but could prevent aneuploidy and tumor formation. Here, we acutely...
An evaluation of commercial fluorescent bead-based luminex cytokine assays.
Joel Fleury Djoba Siawaya, Teri Roberts, Chantal Babb, Gillian Black, Hawa Jande Golakai, Kim Stanley, Nchinya Bennedict Bapela, Eileen Hoal, Shreemanta Parida, Paul van Helden, Gerhard Walzl
Apr 16, 2018
The recent introduction of fluorescent bead-based technology, allowing the measurement of multiples analytes in a single 25-50 microl sample has revolutionized the study of cytokine responses. However, such multiplex approaches...
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