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Friedrich Christoph Oetinger’s Speculative Pietism
Sean J. McGrath
Aug 29, 2018
The influence of Friedrich Christoph Oetinger (1702-82) on Schelling’s work is even deeper than that exerted by Jakob Boehme, deeper, not because Schelling devoted more scholarly attention to Oetinger than he did to the study of...
Friedrich Christoph Oetinger’s Speculative Pietism
Sean J. McGrath
Aug 29, 2018
The influence of Friedrich Christoph Oetinger (1702-82) on Schelling’s work is even deeper than that exerted by Jakob Boehme, deeper, not because Schelling devoted more scholarly attention to Oetinger than he did to the study of...
G-Quadruplexes
Guanine (G)-rich sequences in nucleic acids can assemble into G-quadruplex structures that involve G-quartets linked by loop nucleotides. The structural and topological diversity of G-quadruplexes have attracted great attention...
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Remote stereocontrol in [3,3]-sigmatropic rearrangements
The Ireland - Claisen [3,3]-sigmatropic rearrangement has been used to access biologically important β,β′-dihydroxy α-amino acids. The rearrangement reported is highly stereoselective and offers excellent levels of remote...
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RNA promotes phase separation of glycolysis enzymes into yeast G bodies in hypoxia.
In hypoxic stress conditions, glycolysis enzymes assemble into singular cytoplasmic granules called glycolytic (G) bodies. G body formation in yeast correlates with increased glucose consumption and cell survival. However, the...
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Remote stereocontrol in [3,3]-sigmatropic rearrangements
The Ireland - Claisen [3,3]-sigmatropic rearrangement has been used to access biologically important β,β′-dihydroxy α-amino acids. The rearrangement reported is highly stereoselective and offers excellent levels of remote...
Published by:
Modelling and simulation of biased agonism dynamics at a G protein-coupled receptor.
Theoretical models of G protein-coupled receptor (GPCR) concentration-response relationships often assume an agonist producing a single functional response via a single active state of the receptor. These models have largely...
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Amino-Acid-Derived Naphthalenediimides as Versatile G-Quadruplex Binders

The design and synthesis of water soluble, amino-acid-functionalised naphthalenediimides (NDIs) as potential ligands of native G-quadruplexes is reported. The NDIs were tested on a panel of oncogene promoters, on the human...

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Amino-Acid-Derived Naphthalenediimides as Versatile G-Quadruplex Binders

The design and synthesis of water soluble, amino-acid-functionalised naphthalenediimides (NDIs) as potential ligands of native G-quadruplexes is reported. The NDIs were tested on a panel of oncogene promoters, on the human...

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Substitution of the native <i>srfA</i> promoter by constitutive P<i>veg</i> in two <i>B. subtilis </i>strains and evaluation of the effect on surfactin production
The genetic enhancement of Surfactin production increasingly gained attention in the last years, since relatively low product yields limit the industrial application of this biosurfactant. The natural quorum sensing regulation...
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Substitution of the native <i>srfA</i> promoter by constitutive P<i>veg</i> in two <i>B. subtilis </i>strains and evaluation of the effect on surfactin production
The genetic enhancement of Surfactin production increasingly gained attention in the last years, since relatively low product yields limit the industrial application of this biosurfactant. The natural quorum sensing regulation...
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