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Exploring Students' Perspectives on the Implementation of a Self-Organised Learning Environment
Shatha Almalki
Jan 01, 2024
This critical participatory action research explored undergraduate female Saudi students' perspectives on the implications of a self-organised learning environment (SOLE) via their mobile devices. Data was gathered from...
Gastric pouches and the mucociliary sole
Prerequisite for tracing nervous system evolution is understanding of the body plan, feeding behaviour and locomotion of the first animals in which neurons evolved. Here, a comprehensive scenario is presented for the...
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G-Quadruplexes
Guanine (G)-rich sequences in nucleic acids can assemble into G-quadruplex structures that involve G-quartets linked by loop nucleotides. The structural and topological diversity of G-quadruplexes have attracted great attention...
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Multidrug resistant enteric fever in South Asia
Investments in newer diagnostics and antimicrobial treatments are critical to improve management of enteric fever in South Asia, say Christopher Parry and colleagues
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Comparison of sole nurse and team-delivered community clozapine services for people with treatment-resistant schizophrenia
Aim. To compare sole nurse and doctor-led multidisciplinary team delivery of
community clozapine services for people with treatment-resistant schizophrenia.
Background. Around 20% of people with schizophrenia are...
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Comparison of sole nurse and team-delivered community clozapine services for people with treatment-resistant schizophrenia
Aim. To compare sole nurse and doctor-led multidisciplinary team delivery of
community clozapine services for people with treatment-resistant schizophrenia.
Background. Around 20% of people with schizophrenia are...
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Remote stereocontrol in [3,3]-sigmatropic rearrangements
The Ireland - Claisen [3,3]-sigmatropic rearrangement has been used to access biologically important β,β′-dihydroxy α-amino acids. The rearrangement reported is highly stereoselective and offers excellent levels of remote...
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Minimal configurations and sandpile measures
We give a new simple construction of the sandpile measure on an infinite graph G, under the sole assumption that each tree in the Wired Uniform Spanning Forest on G has one end almost surely. For so called generalized minimal...
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Minimal configurations and sandpile measures
We give a new simple construction of the sandpile measure on an infinite graph G, under the sole assumption that each tree in the Wired Uniform Spanning Forest on G has one end almost surely. For so called generalized minimal...
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Activation mechanism of the class D fungal GPCR dimer Ste2.
The fungal class D1 G-protein-coupled receptor (GPCR) Ste2 has a different arrangement of transmembrane helices compared with mammalian GPCRs and a distinct mode of coupling to the heterotrimeric G protein Gpa1-Ste2-Ste181. In...
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RNA promotes phase separation of glycolysis enzymes into yeast G bodies in hypoxia.
In hypoxic stress conditions, glycolysis enzymes assemble into singular cytoplasmic granules called glycolytic (G) bodies. G body formation in yeast correlates with increased glucose consumption and cell survival. However, the...
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THE CONCISE GUIDE TO PHARMACOLOGY 2019/20
The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective...
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Remote stereocontrol in [3,3]-sigmatropic rearrangements
The Ireland - Claisen [3,3]-sigmatropic rearrangement has been used to access biologically important β,β′-dihydroxy α-amino acids. The rearrangement reported is highly stereoselective and offers excellent levels of remote...
Published by:
Modelling and simulation of biased agonism dynamics at a G protein-coupled receptor.
Theoretical models of G protein-coupled receptor (GPCR) concentration-response relationships often assume an agonist producing a single functional response via a single active state of the receptor. These models have largely...
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THE CONCISE GUIDE TO PHARMACOLOGY 2017/18
The Concise Guide to PHARMACOLOGY 2017/18 provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to an open access...
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Activation mechanism of the class D fungal GPCR dimer Ste2.
The fungal class D1 G-protein-coupled receptor (GPCR) Ste2 has a different arrangement of transmembrane helices compared with mammalian GPCRs and a distinct mode of coupling to the heterotrimeric G protein Gpa1-Ste2-Ste181. In...
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Amino-Acid-Derived Naphthalenediimides as Versatile G-Quadruplex Binders

The design and synthesis of water soluble, amino-acid-functionalised naphthalenediimides (NDIs) as potential ligands of native G-quadruplexes is reported. The NDIs were tested on a panel of oncogene promoters, on the human...

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Amino-Acid-Derived Naphthalenediimides as Versatile G-Quadruplex Binders

The design and synthesis of water soluble, amino-acid-functionalised naphthalenediimides (NDIs) as potential ligands of native G-quadruplexes is reported. The NDIs were tested on a panel of oncogene promoters, on the human...

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Cycle-Induced Interfacial Degradation and Transition-Metal Cross-Over in LiNi0.8Mn0.1Co0.1O2-Graphite Cells.
Ni-rich lithium nickel manganese cobalt (NMC) oxide cathode materials promise Li-ion batteries with increased energy density and lower cost. However, higher Ni content is accompanied by accelerated degradation and thus poor...
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