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Results: 91
A drug-discovery-oriented non-invasive protocol for protein crystal cryoprotection by dehydration, with application for crystallization screening.
Dom Bellini
Apr 02, 2022
In X-ray macromolecular crystallography, cryoprotection of crystals mounted on harvesting loops is achieved when the water in the sample solvent transitions to vitreous ice before crystalline ice forms. This is achieved by rapid...
The FUSION protein crystallization screen.
The success and speed of atomic structure determination of biological macromolecules by X-ray crystallography depends critically on the availability of diffraction-quality crystals. However, the process of screening...
Quantum Depletion of a Homogeneous Bose-Einstein Condensate.
Raphael Lopes, Christoph Eigen, Nir Navon, David Clément, Robert P Smith, Zoran Hadzibabic
Jun 13, 2018
We measure the quantum depletion of an interacting homogeneous Bose-Einstein condensate and confirm the 70-year-old theory of Bogoliubov. The observed condensate depletion is reversibly tunable by changing the strength of the...
Monocytes and macrophages in abdominal aortic aneurysm.
Juliette Raffort, Fabien Lareyre, Marc Clément, Réda Hassen-Khodja, Giulia Chinetti, Ziad Mallat
Jun 21, 2018
Abdominal aortic aneurysm (AAA) is a life-threatening disease associated with high morbidity, and high mortality in the event of aortic rupture. Major advances in open surgical and endovascular repair of AAA have been achieved...
Necrotic Cell Sensor Clec4e Promotes a Proatherogenic Macrophage Phenotype Through Activation of the Unfolded Protein Response.
Marc Clément, Gemma Basatemur, Leanne Masters, Lauren Baker, Patrick Bruneval, Takao Iwawaki, Manfred Kneilling, Sho Yamasaki, Jane Goodall, Ziad Mallat
Nov 14, 2016
Luminescent Solar Concentrators Based on Energy Transfer from an Aggregation-Induced Emitter Conjugated Polymer.
Guanpeng Lyu, James Kendall, Ilaria Meazzini, Eduard Preis, Sebnem Bayseç, Ullrich Scherf, Sébastien Clément, Rachel C Evans
Dec 19, 2019
Luminescent solar concentrators (LSCs) are solar-harvesting devices fabricated from a transparent waveguide that is doped or coated with lumophores. Despite their potential for architectural integration, the optical efficiency...
A self-assembly toolbox for thiophene-based conjugated polyelectrolytes
Judith E Houston, Michèle Chevrier, Marie-Sousai Appavou, Stephen M King, Sébastien Clément, Rachel C Evans
Apr 25, 2018
Targeted control of the aggregation, morphology and optical properties of conjugated polymers is critical for the development of high performance optoelectronic devices. Here, self-assembly approaches are used to strategically...
Expanding the light absorption of poly(3-hexylthiophene) by end-functionalization with π-extended porphyrins.
Michèle Chevrier, Sébastien Richeter, Olivier Coulembier, Mathieu Surin, Ahmad Mehdi, Roberto Lazzaroni, Rachel C Evans, Philippe Dubois, Sébastien Clément
Jul 03, 2018
Poly(3-hexylthiophene)s end-functionalized with π-extended porphyrins have been synthesized in a one-pot procedure. The polymers show a broad absorption profile extending to 700 nm and a fibrillar microstructure, which can be...
Structures of B. subtilis Maturation RNases Captured on 50S Ribosome with Pre-rRNAs.
Stephanie Oerum, Tom Dendooven, Marjorie Catala, Laetitia Gilet, Clément Dégut, Aude Trinquier, Maxime Bourguet, Pierre Barraud, Sarah Cianferani, Ben F Luisi, Ciarán Condon, Carine Tisné
Jan 06, 2021
The pathways for ribosomal RNA (rRNA) maturation diverge greatly among the domains of life. In the Gram-positive model bacterium, Bacillus subtilis, the final maturation steps of the two large ribosomal subunit (50S) rRNAs, 23S...
Excitonic Emission of Monolayer Semiconductors Near-Field Coupled to High-Q Microresonators.
Clément Javerzac-Galy, Anshuman Kumar, Ryan D Schilling, Nicolas Piro, Sina Khorasani, Matteo Barbone, Ilya Goykhman, Jacob B Khurgin, Andrea C Ferrari, Tobias J Kippenberg
Sep 05, 2018
We present quantum yield measurements of single layer WSe2 (1L-WSe2) integrated with high-Q ( Q > 106) optical microdisk cavities, using an efficient (η > 90%) near-field coupling scheme based on a tapered optical fiber....
A comparative analysis of the vestibular apparatus in Epipliopithecus vindobonensis
Alessandro Urciuoli, Clément Zanolli, Amélie Beaudet, Marta Pina, Sergio Almécija, Salvador Moyà-Solà, David M Alba
May 24, 2021
Pliopithecoids are an extinct group of catarrhine primates from the Miocene of Eurasia. More than 50 years ago, they were linked to hylobatids due to some morphological similarities, but most subsequent studies have supported a...
Genome Expression Dynamics Reveal the Parasitism Regulatory Landscape of the Root-Knot Nematode Meloidogyne incognita and a Promoter Motif Associated with Effector Genes.
Martine Da Rocha, Caroline Bournaud, Julie Dazenière, Peter Thorpe, Marc Bailly-Bechet, Clément Pellegrin, Arthur Péré, Priscila Grynberg, Laetitia Perfus-Barbeoch, Sebastian Eves-van den Akker, Etienne GJ Danchin
Jul 30, 2021
Root-knot nematodes (genus Meloidogyne) are the major contributor to crop losses caused by nematodes. These nematodes secrete effector proteins into the plant, derived from two sets of pharyngeal gland cells, to manipulate host...
Molecular mechanism of Mad1 kinetochore targeting by phosphorylated Bub1.
Elyse S Fischer, Conny WH Yu, Dom Bellini, Stephen H McLaughlin, Christian M Orr, Armin Wagner, Stefan MV Freund, David Barford
May 20, 2021
Deep learning-based quantification of arbuscular mycorrhizal fungi in plant roots.
Edouard Evangelisti, Carl Turner, Alice McDowell, Liron Shenhav, Temur Yunusov, Aleksandr Gavrin, Emily K Servante, Clément Quan, Sebastian Schornack
Aug 18, 2021
Lattice Dynamics in the NASICON NaZr2(PO4)3 Solid Electrolyte from Temperature-Dependent Neutron Diffraction, NMR, and Ab Initio Computational Studies.
Emily E Morgan, Hayden A Evans, Kartik Pilar, Craig M Brown, Raphaële J Clément, Ryo Maezono, Ram Seshadri, Bartomeu Monserrat, Anthony K Cheetham
Jun 16, 2022
Natrium super ionic conductor (NASICON) compounds form a rich and highly chemically tunable family of crystalline materials that are of widespread interest because they include exemplars with high ionic conductivity, low thermal...
Manganese doping for enhanced magnetic brightening and circular polarization control of dark excitons in paramagnetic layered hybrid metal-halide perovskites
Vascular Smooth Muscle Cell Plasticity and Autophagy in Dissecting Aortic Aneurysms.
Marc Clément, Joel Chappell, Juliette Raffort, Fabien Lareyre, Marie Vandestienne, Annabel L Taylor, Alison Finigan, James Harrison, Martin R Bennett, Patrick Bruneval, Soraya Taleb, Helle F Jørgensen, Ziad Mallat
Mar 29, 2019
Objective- Recent studies suggested the occurrence of phenotypic switching of vascular smooth muscle cells (VSMCs) during the development of aortic aneurysm (AA). However, lineage-tracing studies are still lacking, and the...
Angiotensin II Autophagy clones Endoplasmic Reticulum Inflammation Mice Smooth muscle cells Adult Aged aortic dissection Angiotensin II Animals Aorta Aortic Aneurysm Autophagy Autophagy-Related Protein 5 Cell Lineage Cell Plasticity Cells Cultured Disease Models Animal Endoribonucleases Female Humans Male Mice 129 Strain Mice Inbred C57BL Mice Knockout ApoE Middle Aged Muscle Smooth Vascular Myocytes Smooth Muscle Phenotype Protein Serine-Threonine Kinases Signal Transduction
Myeloid-Epithelial-Reproductive Receptor Tyrosine Kinase and Milk Fat Globule Epidermal Growth Factor 8 Coordinately Improve Remodeling After Myocardial Infarction via Local Delivery of Vascular Endothelial Growth Factor.
Kiave-Yune Howangyin, Ivana Zlatanova, Cristina Pinto, Anta Ngkelo, Clément Cochain, Marie Rouanet, José Vilar, Mathilde Lemitre, Christian Stockmann, Bernd K Fleischmann, Ziad Mallat, Jean-Sébastien Silvestre
Jun 21, 2018
BACKGROUND: In infarcted heart, improper clearance of dying cells by activated neighboring phagocytes may precipitate the transition to heart failure. We analyzed the coordinated role of 2 major mediators of efferocytosis, the...
Inflammation MACROPHAGES Myocardial Infarction myocarditis Neovascularization Physiologic Animals Antigens surface MACROPHAGES Mice Mice Inbred C57BL Mice Knockout Mice Transgenic Milk Proteins Myocardial Infarction Phagocytosis Proto-Oncogene Proteins Receptor Protein-Tyrosine Kinases Vascular Endothelial Growth Factor A Ventricular Remodeling c-Mer Tyrosine Kinase
A Combined Experimental and Turbulence-Resolved Modeling Approach for Aeroengine Turbine Rim Seals
Simon Vella, Peter Darby, Mauro Carnevale, James A. Scobie, Gary D. Lock, Clément Jarrossay, Francesco Salvatori, Damien Bonneau, Carl M. Sangan
Aug 01, 2024
Ingress is the penetration of hot mainstream gas into the rotor–stator wheel-space formed between adjacent disks; a rim seal is installed at the periphery of the wheel-space. Purge flow is bled from the compressor and...
aeroengine turbine rim seals cavity flows high fidelity computations improved delayed detached eddy simulation (IDDES) /dk/atira/pure/subjectarea/asjc/2200/2210 name=Mechanical Engineering /dk/atira/pure/subjectarea/asjc/2200/2202 name=Aerospace Engineering /dk/atira/pure/subjectarea/asjc/2100/2102 name=Energy Engineering and Power Technology /dk/atira/pure/subjectarea/asjc/2100/2103 name=Fuel Technology /dk/atira/pure/subjectarea/asjc/2100/2104 name=Nuclear Energy and Engineering
Mediation and modification of genetic susceptibility to obesity by eating behaviors.
Blandine de Lauzon-Guillain, Emma Ad Clifton, Felix R Day, Karine Clément, Soren Brage, Nita G Forouhi, Simon J Griffin, Yves Akoli Koudou, Véronique Pelloux, Nicholas J Wareham, Marie-Aline Charles, Barbara Heude, Ken K Ong
Aug 29, 2017
BMI Body Mass Index dieting eating behavior genetic risk score Genetics obesity Adult Appetite Body Mass Index Cognition Eating Emotions Feeding Behavior Female Gene-Environment Interaction Genetic Predisposition to Disease Humans Hyperphagia Male Middle Aged obesity Risk Factors self-control Sex Factors Surveys and Questionnaires
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