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Developing an Online Interactive Guide for Law Students
This article by Jenni Crossley and Claire Tylee examines the process of developing an online interactive guide for law students by librarians at the University of the West of England. The guide was based on material contained in...
Developing an Online Interactive Guide for Law Students
This article by Jenni Crossley and Claire Tylee examines the process of developing an online interactive guide for law students by librarians at the University of the West of England. The guide was based on material contained in...
Ruthenium-Catalyzed para-Selective C−H Alkylation of Aniline Derivatives
Jamie A. Leitch, Claire L. McMullin, Andrew J. Paterson, Mary F. Mahon, Yunas Bhonoah, Christopher G. Frost
Nov 20, 2017
The para-selective C−H alkylation of aniline derivatives furnished with a pyrimidine auxiliary is herein reported. This reaction is proposed to take place via an N−H-activated cyclometalate formed in situ. Experimental and DFT...
Ruthenium-Catalyzed para-Selective C−H Alkylation of Aniline Derivatives
Jamie A. Leitch, Claire L. McMullin, Andrew J. Paterson, Mary F. Mahon, Yunas Bhonoah, Christopher G. Frost
Nov 20, 2017
The para-selective C−H alkylation of aniline derivatives furnished with a pyrimidine auxiliary is herein reported. This reaction is proposed to take place via an N−H-activated cyclometalate formed in situ. Experimental and DFT...
The Use of Technological Innovations in Promoting Effective Humanitarian Aid
The number and scale of natural and man-made disasters is increasing at an unprecedented rate, leading to devastating consequences for citizens, governments and entire economies. In response, Humanitarian Supply Chains (HSC) are...
Published by: IGI Global Scientific Publishing
FORWARDS-1
LM Paterson, D Barker, S Cro, P Mozgunov, R Phillips, C Smith, L Nahar, S Paterson, AR Lingford-Hughes
Oct 24, 2022
BACKGROUND: Treatment of opiate addiction with opiate substitution treatment (e.g. methadone) is beneficial. However, some individuals desire or would benefit from abstinence but there are limited options to attenuate problems...
Optimizing Water Quality Sampling Through Application Of Real Time Ionic Concentration Regression Models
The Water Resources Management Division of the Department of Environment and Conservation performs routine water sampling to measure the physical and chemical parameters of select water bodies in Newfoundland and Labrador. Ionic...
Predicting radiotherapy-induced xerostomia in head and neck cancer patients using day-to-day kinetics of radiomics features.
Thomas Berger, David J Noble, Leila EA Shelley, Thomas McMullan, Amy Bates, Simon Thomas, Linda J Carruthers, George Beckett, Aileen Duffton, Claire Paterson, Raj Jena, Duncan B McLaren, Neil G Burnet, William H Nailon
Dec 18, 2022
BACKGROUND AND PURPOSE: The images acquired during radiotherapy for image-guidance purposes could be used to monitor patient-specific response to irradiation and improve treatment personalisation. We investigated whether the...
The Role of Faculty Development in Online Universities
Faculty development continues to be an important topic in online education. As online program and course offerings are growing and adopted in popularity with many traditional brick and mortar universities, it is causing many...
Published by: IGI Global Scientific Publishing
Optimizing Water Quality Sampling Through Application Of Real Time Ionic Concentration Regression Models
The Water Resources Management Division of the Department of Environment and Conservation performs routine water sampling to measure the physical and chemical parameters of select water bodies in Newfoundland and Labrador. Ionic...
FORWARDS-1
LM Paterson, D Barker, S Cro, P Mozgunov, R Phillips, C Smith, L Nahar, S Paterson, AR Lingford-Hughes
Nov 18, 2022
BACKGROUND: Treatment of opiate addiction with opiate substitution treatment (e.g. methadone) is beneficial. However, some individuals desire or would benefit from abstinence but there are limited options to attenuate problems...
Adaptive Addiction Baclofen Bayesian dependence dose escalation GABA-B Methadone opiate phase I Humans Analgesics Opioid Baclofen Bayes Theorem Carbon Dioxide Cholecalciferol GABA-B Receptor Agonists Hypnotics and Sedatives Methadone Nicotine Opiate substitution treatment Opioid-Related Disorders Single-Blind Method vitamin D
The emergence of mecC methicillin-resistant Staphylococcus aureus.
Conquering peaks and illuminating depths
The structural complexity and biological importance of macrolide natural products has inspired the development of innovative strategies for their chemical synthesis. With their dense stereochemical content, high level of...
Total synthesis of the actinoallolides and a designed photoaffinity probe for target identification.
The actinoallolides are a family of polyketide natural products isolated from the bacterium Actinoallomurus fulvus. They show potent biological activity against trypanosomes, the causative agents of the neglected tropical...
Stereocontrolled Synthesis as an Enabling Tool for the Configurational Assignment of Marine Polyketide Natural Products
Through the judicious use of stereocontrolled transformations in combination with detailed experimental and computational NMR studies, this Minireview highlights recent synthetic work on stereochemically ambiguous marine...
Stereocontrolled Synthesis as an Enabling Tool for the Configurational Assignment of Marine Polyketide Natural Products
Through the judicious use of stereocontrolled transformations in combination with detailed experimental and computational NMR studies, this Minireview highlights recent synthetic work on stereochemically ambiguous marine...
A synthesis-enabled relative stereochemical assignment of the C1-C28 region of hemicalide.
Through synthesising both candidate diastereomers of a model C1-C28 fragment of the potent cytotoxic marine polyketide hemicalide, an assignment of the relative configuration between the C1-C15 and C16-C26 regions has been...
Enantioselective Intermolecular C-H Amination Directed by a Chiral Cation.
The enantioselective amination of C(sp3)-H bonds is a powerful synthetic transformation yet highly challenging to achieve in an intermolecular sense. We have developed a family of anionic variants of the...
Published by: Journal of the American Chemical Society
A Unified Total Synthesis of the Actinoallolides, a Family of Potent Anti-Trypanosomal Macrolides.
Trypanosoma protozoan parasites are the causative agents of Chagas disease and sleeping sickness, two neglected tropical diseases where there is an urgent need for improved treatments and the evaluation of promising drug leads...
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