Search
Results: 797
BEATRICE RENFIELD LECTURESHIP
The Rockefeller University
Jan 01, 0001
Clare Hastings, R.N., Ph.D., FAAN: The Past, Present, and Future of Clinical Research Nursing
Published by: The Rockefeller University
A roadmap to advance dementia research in prevention, diagnosis, intervention, and care by 2025.
James Pickett, Cathy Bird, Clive Ballard, Sube Banerjee, Carol Brayne, Katherine Cowan, Linda Clare, Adelina Comas-Herrera, Lynne Corner, Stephanie Daley, Martin Knapp, Louise Lafortune, Gill Livingston, Jill Manthorpe, Natalie Marchant, Jo Moriarty, Louise Robinson, Clare van Lynden, Gill Windle, Bob Woods, Katherine Gray, Clare Walton
Apr 04, 2018
OBJECTIVE: National and global dementia plans have focused on the research ambition to develop a cure or disease-modifying therapy by 2025, with the initial focus on investment in drug discovery approaches. We set out to develop...
Unsteady coating flow on a rotating cylinder in the presence of an irrotational airflow with circulation
Unsteady two-dimensional coating flow of a thin film of a viscous fluid on the outside of a uniformly rotating horizontal circular cylinder in the presence of a steady two-dimensional irrotational airflow with circulation is...
Unsteady coating flow on a rotating cylinder in the presence of an irrotational airflow with circulation
Unsteady two-dimensional coating flow of a thin film of a viscous fluid on the outside of a uniformly rotating horizontal circular cylinder in the presence of a steady two-dimensional irrotational airflow with circulation is...
Too hard, too easy, or just right? The effects of context on effort and boredom aversion
Despite people’s general desire to avoid cognitive effort, there is a limit to our parsimony: boredom, a state defined by a lack of successful mental engagement, is found to be similarly aversive. The work presented here...
Anti-commensal IgG Drives Intestinal Inflammation and Type 17 Immunity in Ulcerative Colitis.
Tomas Castro-Dopico, Thomas W Dennison, John R Ferdinand, Rebeccah J Mathews, Aaron Fleming, Dean Clift, Benjamin J Stewart, Chenzhi Jing, Konstantina Strongili, Larisa I Labzin, Edward JM Monk, Kourosh Saeb-Parsy, Clare E Bryant, Simon Clare, Miles Parkes, Menna R Clatworthy
Feb 18, 2019
Inflammatory bowel disease is a chronic, relapsing condition with two subtypes, Crohn's disease (CD) and ulcerative colitis (UC). Genome-wide association studies (GWASs) in UC implicate a FCGR2A variant that alters the binding...
Fcγ receptors IL-1β IgG inflammatory bowel disease type 17 immunity Animals Antibodies Bacterial Colitis Colitis Ulcerative Dextran Sulfate Gastrointestinal Microbiome Gene Expression Regulation Genotype Humans Immunoglobulin G Inflammation Interleukin-1beta Interleukin-8 Intestinal Mucosa MACROPHAGES Mice Phagocytes RNA Messenger Reactive Oxygen Species Receptors IgG Th17 Cells
Too hard, too easy, or just right? The effects of context on effort and boredom aversion
Despite people’s general desire to avoid cognitive effort, there is a limit to our parsimony: boredom, a state defined by a lack of successful mental engagement, is found to be similarly aversive. The work presented here...
The effects of dislocations on crystallographic twins and domain wall motion in magnetite at the Verwey transition.
Anna K Lindquist, Joshua M Feinberg, Richard J Harrison, James C Loudon, Andrew J Newell
Feb 01, 2019
"Patient reported outcomes" following experimental surgery-using telemetry to assess movement in experimental ovine models.
Many potential treatments for orthopedic disease fail at the animal to human translational hurdle. One reason for this failure is that the majority of pre-clinical outcome measurements emphasize structural changes, such as gross...
Orangeburg Girls Winter Edition Jan. 7, 1947
Winthrop News Service
Jan 01, 0001
Clare Smith and Georgia Ann Sims, both of Orangeburg, South Carolina, published submissions in The Journal, Winthrop College's literary publication. Miss Smith, a sophomore at Winthrop, submitted a poem and a character sketch to...
Published by: Winthrop University
Communicating Science Concepts to Individuals with Visual Impairments Using Short Learning Modules
Anthony S Stender, Ryan Newell, Eduardo Villarreal, Dayne F Swearer, Elisabeth Bianco, Emilie Ringe
Oct 10, 2018
Of the 6.7 million individuals in the United States who are visually impaired, 63% are unemployed, and 59% have not attained an education beyond a high school diploma. Providing a basic science education to children and adults...
Evaluation of rodent-only toxicology for early clinical trials with novel cancer therapeutics.
Preclinical toxicology studies are performed prior to phase I trials with novel cancer therapeutics to identify a safe clinical starting dose and potential human toxicities. The primary aim of this study was to evaluate the...
Selection and visualisation of outcome measures for complex post-acute acquired brain injury rehabilitation interventions.
Catherine Elaine Longworth Ford, Donna Malley, Andrew Bateman, Isabel CH Clare, Adam P Wagner, Fergus Gracey
Jun 03, 2016
Protein CoAlation
Yugo Tsuchiya, Sew Yeu Peak-Chew, Clare Newell, Sheritta Miller-Aidoo, Sriyash Mangal, Alexander Zhyvoloup, Jovana Bakovic, Oksana Malanchuk, Gonçalo C Pereira, Vassilios Kotiadis, Gyorgy Szabadkai, Michael R Duchen, Mark Campbell, Sergio Rodriguez Cuenca, Antonio Vidal-Puig, Andrew M James, Michael P Murphy, Valeriy Filonenko, Mark Skehel, Ivan Gout
Oct 09, 2020
Coenzyme A (CoA) is an obligatory cofactor in all branches of life. CoA and its derivatives are involved in major metabolic pathways, allosteric interactions and the regulation of gene expression. Abnormal biosynthesis and...
Coenzyme A metabolic and oxidative stress post-translational modification Proteomics Animals Coenzyme A Cysteine HEK293 Cells Hep G2 Cells Humans Kidney Liver Male Myocardium Organ Specificity Oxidation-Reduction Oxidative Stress Protein Processing Post-Translational Proteins Rabbits Rats Sprague-Dawley Sulfhydryl Compounds
Ocular adverse events associated with immune checkpoint inhibitors
Orthi Shahzad, Nicola Thompson, Gerry Clare, Sarah Welsh, Erika Damato, Philippa Corrie
Apr 09, 2021
Ocular immune-related adverse events (IrAEs) associated with use of checkpoint inhibitors (CPIs) in cancer therapeutics are relatively rare, occurring in approximately 1% of treated patients. Recognition and early intervention...
Masks and Performance as Representations of Gender Oppression and Repression in Edith Wharton's <em>The House of Mirth and Nella Larsen's Passing</em>
Carrie A Wilson
Jan 01, 0001
Edith Wharton and Nella Larsen's literature focus on metaphorically representing gender oppression and repression as masked social performances that result in death being the ultimate release from the drama. Edith Wharton's The...
feminism modernism intersectional Literature Gender Roles masquerade performance DEATH Liberation Feminist, Gender, and Sexuality Studies Modern Literature Women's Studies
Published by: Winthrop University
Tensions between policy and practice
Autonomy Human Rights Involuntary treatment Mental health legislation Paternalism Adult Commitment of Mentally Ill Dangerous Behavior England Female Health Policy Humans Interview Psychological Length of Stay Male Mental Competency Mental Disorders Observational Studies as Topic Paternalism Patient Admission Patient Advocacy Patient Safety Risk Assessment Treatment Refusal
Cognitive Behavioural Therapy for Sexual Offenders With Autism Spectrum Disorders
The vast majority of individuals with autism do not commit sexual offenses. While there has been some suggestion of a tendency towards anti-social or offending behaviors, a propensity for breaking the law by those with a...
Published by: IGI Global Scientific Publishing
Functional Characterization of Ovine Dorsal Root Ganglion Neurons Reveal Peripheral Sensitization after Osteochondral Defect.
Sampurna Chakrabarti, Minji Ai, Katherine Wong, Karin Newell, Frances MD Henson, Ewan St John Smith
Sep 05, 2021
A single ultrasensitive assay for detection and discrimination of tau aggregates of Alzheimer and Pick diseases
Michael A., II Metrick, Natália do Carmo Ferreira, Eri Saijo, Allison Kraus, Kathy Newell, Gianluigi Zanusso, Michele Vendruscolo, Bernardino Ghetti, Byron Caughey
Feb 21, 2021
Abstract: Multiple neurodegenerative diseases are characterized by aggregation of tau molecules. Adult humans express six isoforms of tau that contain either 3 or 4 microtubule binding repeats (3R or 4R tau). Different diseases...
|
|< |
< |
1 |