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Near-native state imaging by cryo-soft-X-ray tomography reveals remodelling of multiple cellular organelles during HSV-1 infection.
Kamal L Nahas, Viv Connor, Katharina M Scherer, Clemens F Kaminski, Maria Harkiolaki, Colin M Crump, Stephen C Graham
Aug 07, 2022
A fluorescent reporter system enables spatiotemporal analysis of host cell modification during herpes simplex virus-1 replication.
Katharina M Scherer, James D Manton, Timothy K Soh, Luca Mascheroni, Vivienne Connor, Colin M Crump, Clemens F Kaminski
Jan 07, 2021
Herpesviruses are large and complex viruses that have a long history of coevolution with their host species. One important factor in the virus-host interaction is the alteration of intracellular morphology during viral...
Cytoskeleton Fluorescence herpesvirus host–pathogen interaction microscopic imaging Microscopy Organelle Animals Capsid Chlorocebus aethiops Cytoplasm Genes Reporter Golgi Apparatus Herpesvirus 1 Human Humans Microscopy Fluorescence Single-Cell Analysis Spatio-Temporal Analysis Vero Cells Virus Assembly Virus Replication
Temporal Proteomic Analysis of BK Polyomavirus Infection Reveals Virus-Induced G2 Arrest and Highly Effective Evasion of Innate Immune Sensing.
Laura G Caller, Colin TR Davies, Robin Antrobus, Paul J Lehner, Michael P Weekes, Colin M Crump
May 22, 2019
Structural analysis of herpes simplex virus by optical super-resolution imaging.
Romain F Laine, Anna Albecka, Sebastian van de Linde, Eric J Rees, Colin M Crump, Clemens F Kaminski
Jan 30, 2015
Animals Antibodies Monoclonal Cell Line Cryoelectron Microscopy Female Herpesvirus 1 Human Humans Image Processing Computer-Assisted Keratinocytes Mice Mice Inbred BALB C Microscopy Microscopy Fluorescence Optical Imaging Recombinant Proteins Simplexvirus Viral Envelope Proteins Viral Proteins Viral Structural Proteins Virion
Near-native state imaging by cryo-soft-X-ray tomography reveals remodelling of multiple cellular organelles during HSV-1 infection
Kamal L Nahas, Viv Connor, Katharina M Scherer, Clemens F Kaminski, Maria Harkiolaki, Colin M Crump, Stephen C Graham
Jul 07, 2022
The VPS4 component of the ESCRT machinery plays an essential role in HPV infectious entry and capsid disassembly.
Justyna Broniarczyk, David Pim, Paola Massimi, Martina Bergant, Anna Goździcka-Józefiak, Colin Crump, Lawrence Banks
Aug 15, 2018
Human Papillomavirus (HPV) infection involves multiple steps, from cell attachment, through endocytic trafficking towards the trans-Golgi network, and, ultimately, the entry into the nucleus during mitosis. An essential viral...
ATPases Associated with Diverse Cellular Activities Capsid Proteins Cell Line Cells Cultured Endosomal Sorting Complexes Required for Transport Humans Papillomaviridae Papillomavirus Infections Protein Binding Protein Transport Vacuolar Proton-Translocating ATPases Viral Proteins Virus Internalization Virus Uncoating
Interview with Johann M. McCrackin
Johann M. McCrackin
Jan 01, 0001
Interview with Johann M. McCrackin, 1984 South Carolina Mother of the Year.
Published by: Winthrop University
Polymorphism in M(H2PO2)3 (M = V, Al, Ga) compounds with the perovskite-related ReO3 structure.
Hayden A Evans, Zeyu Deng, Ines E Collings, Yue Wu, Jessica L Andrews, Kartik Pilar, Joshua M Tuffnell, Guang Wu, John Wang, Siân E Dutton, Paul D Bristowe, Ram Seshadri, Anthony K Cheetham
Feb 18, 2019
Trivalent metal hypophosphites with the general formula M(H2PO2)3 (M = V, Al, Ga) adopt the ReO3 structure, with each compound displaying two structural polymorphs. High-pressure synchrotron X-ray studies reveal a...
Temporal Proteomic Analysis of Herpes Simplex Virus 1 Infection Reveals Cell-Surface Remodeling via pUL56-Mediated GOPC Degradation.
Timothy K Soh, Colin TR Davies, Julia Muenzner, Leah M Hunter, Henry G Barrow, Viv Connor, Clément R Bouton, Cameron Smith, Edward Emmott, Robin Antrobus, Stephen C Graham, Michael P Weekes, Colin M Crump
Sep 16, 2020
Herpesviruses are ubiquitous in the human population and they extensively remodel the cellular environment during infection. Multiplexed quantitative proteomic analysis over the time course of herpes simplex virus 1 (HSV-1)...
Thomas M. Rivers, 1934
The Rockefeller University
Jan 01, 0001
Dr. Thomas M. Rivers. Filterable Viruses with Particular Reference to Psittacosis
Lecture delivered April 19th, 1934
Posted with permission
Published by: The Williams & Wilkins Company
Research on the Influential Factors of Bilingual Teaching Based on Colin Baker Model Case Study of Macroeconomics
Bilingual teaching is the manifestation of the internationalization of high education and the key index of undergraduate teaching evaluation. Based on the modified Colin Baker model and the questionnaire of two universities in...
Published by: IGI Global Scientific Publishing
Investigating Students' Intention to Use M-Learning
Mohammed Almulla
Jan 01, 2024
Mobile learning (M-learning) has become a crucial tool for both students and educators. The unified theory of acceptance and use of technology (UTAUT), the technology acceptance model (TAM), and outside factors were all included...
Published by: IGI Global Scientific Publishing
Complete Genome Sequences of BK Polyomavirus Strains from Two Patients with Urinary Tract Infection, Sequenced Using the Ion Torrent Platform.
Graham Rose, Kyriaki Ranellou, Raju Misra, Colin Crump, David Wooldridge, Surendra Parmar, Christopher Maddren, Saheer Gharbia, Hamid Jalal
Feb 26, 2018
BK polyomavirus is an important pathogen in kidney transplant patients. We report here two complete genome sequences, those of isolates CAMB-1035 and CAMB-1055, identified in two urine samples tested for urinary tract infection...
Digital M&A and Firm Innovation
This study empirically examines how digital M&A affects firm innovation using data from Chinese listed companies from 2006 to 2019. The results show that digital M&A promotes firm innovation, and our findings also suggest that...
Published by: IGI Global Scientific Publishing
High voltage sulphate cathodes Li<sub>2</sub>M(SO<sub>4</sub>)<sub>2</sub> (M = Fe, Mn, Co)
The search for high voltage cathodes for lithium-ion batteries has led to recent interest in the monoclinic Li2Fe(SO4)2 material which has a voltage of 3.83 V vs. lithium, the highest recorded for a fluorine-free iron-based...
JEFFREY M. FRIEDMAN
The Rockefeller University
Jan 01, 0001
congratulations to Professor Jeffrey M. Friedman, recipient of the 2010 Albert Lasker Basic Medical Research Award
Published by: The Rockefeller University
Frederick M. Allen, 1916
The Rockefeller University
Jan 01, 0001
Frederick M. Allen, M.D. The Role of Fat in Diabetes.
Delivered November 4th, 1916
Published by: J.B. Lippincott Company
Agnoprotein Is an Essential Egress Factor during BK Polyomavirus Infection.
Margarita-Maria Panou, Emma L Prescott, Daniel L Hurdiss, Gemma Swinscoe, Michael Hollinshead, Laura G Caller, Ethan L Morgan, Louisa Carlisle, Marietta Müller, Michelle Antoni, David Kealy, Neil A Ranson, Colin M Crump, Andrew Macdonald
Sep 26, 2018
BK polyomavirus (BKPyV; hereafter referred to as BK) causes a lifelong chronic infection and is associated with debilitating disease in kidney transplant recipients. Despite its importance, aspects of the virus life cycle remain...
agnoprotein polyomavirus virus exit Animals BK Virus Cell Nucleus Chlorocebus aethiops Gene Expression Regulation Viral Nuclear Envelope Polyomavirus Infections Protein Binding Soluble N-Ethylmaleimide-Sensitive Factor Attachment Proteins Transcription Genetic Vero Cells Viral Regulatory and Accessory Proteins Virion
Insights into herpesvirus assembly from the structure of the pUL7
Benjamin G Butt, Danielle J Owen, Cy M Jeffries, Lyudmila Ivanova, Chris H Hill, Jack W Houghton, Md Firoz Ahmed, Robin Antrobus, Dmitri I Svergun, John J Welch, Colin M Crump, Stephen C Graham
Jun 12, 2020
High voltage sulphate cathodes Li<sub>2</sub>M(SO<sub>4</sub>)<sub>2</sub> (M = Fe, Mn, Co)
The search for high voltage cathodes for lithium-ion batteries has led to recent interest in the monoclinic Li2Fe(SO4)2 material which has a voltage of 3.83 V vs. lithium, the highest recorded for a fluorine-free iron-based...
Mutations in the m-AAA proteases AFG3L2 and SPG7 are causing isolated dominant optic atrophy.
Majida Charif, Arnaud Chevrollier, Naïg Gueguen, Céline Bris, David Goudenège, Valérie Desquiret-Dumas, Stéphanie Leruez, Estelle Colin, Audrey Meunier, Catherine Vignal, Vasily Smirnov, Sabine Defoort-Dhellemmes, Isabelle Drumare Bouvet, Cyril Goizet, Marcela Votruba, Neringa Jurkute, Patrick Yu-Wai-Man, Francesca Tagliavini, Leonardo Caporali, Chiara La Morgia, Valerio Carelli, Vincent Procaccio, Xavier Zanlonghi, Isabelle Meunier, Pascal Reynier, Dominique Bonneau, Patrizia Amati-Bonneau, Guy Lenaers
Jun 26, 2020
OBJECTIVE: To improve the genetic diagnosis of dominant optic atrophy (DOA), the most frequently inherited optic nerve disease, and infer genotype-phenotype correlations. METHODS: Exonic sequences of 22 genes were screened by...
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