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Alpha-synuclein ferrireductase activity is detectible in vivo, is altered in Parkinson's disease and increases the neurotoxicity of DOPAL

The normal cellular role of α-synuclein is of potential importance in understanding diseases in which an aggregated form of the protein has been implicated. A potential loss or change in the normal function of α-synuclein...

Research on the Influential Factors of Bilingual Teaching Based on Colin Baker Model Case Study of Macroeconomics
Wen-Jing Fan, Pan Xian
Dec 23, 2022
Bilingual teaching is the manifestation of the internationalization of high education and the key index of undergraduate teaching evaluation. Based on the modified Colin Baker model and the questionnaire of two universities in...
Interview with Gwen P. Howell
Gwen P. Howell
Jan 01, 0001
Interview with Gwen P. Howell, member of the South Carolina Mothers Association.
Published by: Winthrop University
Alpha-synuclein ferrireductase activity is detectible in vivo, is altered in Parkinson's disease and increases the neurotoxicity of DOPAL

The normal cellular role of α-synuclein is of potential importance in understanding diseases in which an aggregated form of the protein has been implicated. A potential loss or change in the normal function of α-synuclein...

PSK Method for Solving Mixed and Type-4 Intuitionistic Fuzzy Solid Transportation Problems
P. Kumar
Apr 01, 2019
In this article, the author categorises the solid transportation problem (STP) under uncertain environments. He formulates the mixed and fully intuitionistic fuzzy solid transportation problems (FIFSTPs) and utilizes the...
KRAS Allelic Imbalance
The identification of therapeutic vulnerabilities in mutant KRAS tumors has proven difficult to achieve. Burgess and colleagues recently reported in Cell that mutant/wild-type Kras allelic dosage determines clonal fitness and...
‘Waste the waist’

Objectives. To identify an evidence-based intervention to promote changes in diet and physical activity and adapt it for a UK primary care setting for people with high cardiovascular risk.

Design. A three-stage...

‘Waste the waist’

Objectives. To identify an evidence-based intervention to promote changes in diet and physical activity and adapt it for a UK primary care setting for people with high cardiovascular risk.

Design. A three-stage...

Performance Characteristics of Discrete-Time Queue With Variant Working Vacations
P. Laxmi, Rajesh P.
Apr 01, 2020
This article analyzes an infinite buffer discrete-time single server queueing system with variant working vacations in which customers arrive according to a geometric process. As soon as the system becomes empty, the server...
Intrinsically p-biharmonic maps
Peter Hornung, Roger Moser
Nov 01, 2014
For a compact Riemannian manifold $N$, a domain $\Omega \subset \mathbb{R}^m$ and for $p \in (1,\infty)$, we introduce an intrinsic version $E_p$ of the $p$-biharmonic energy functional for maps $u : \Omega \to N$. This requires...
The Synthetic Chemistry of Carboxyalkyl-P, P-Diphenyl Phosphines
Larry S. Andrews
Jan 01, 0001
This 55 page thesis examines the preparation of carboxyalkyl-P and P-diphenyl phosphines to determine their acidity characteristics as a function of structure and to characterize their ability to function as chelating agents.
Published by: Ursinus College
The sum-of-squares hierarchy on the sphere and applications in quantum information theory
Kun Fang, Hamza Fawzi
Oct 09, 2021
Abstract: We consider the problem of maximizing a homogeneous polynomial on the unit sphere and its hierarchy of sum-of-squares relaxations. Exploiting the polynomial kernel technique, we obtain a quadratic improvement of the...
A modern baseline for the paired isotopic analysis of skin and bone in terrestrial mammals.
We present the isotopic discrimination between paired skin and bone collagen from animals of known life history, providing a modern baseline for the interpretation of archaeological isotopic data. At present, the interpretation...
Tracking the British agricultural revolution through the isotopic analysis of dated parchment.
Between the sixteenth and nineteenth century, British agriculture underwent a 'revolutionary' transformation. Yet despite over a century of research and the recognised centrality of agricultural developments to industrialisation...
Diabetes Prediction Using Enhanced SVM and Deep Neural Network Learning Techniques: An Algorithmic Approach for Early Screening of Diabetes
Diabetes, caused by the rise in level of glucose in blood, has many latest devices to identify from blood samples. Diabetes, when unnoticed, may bring many serious diseases like heart attack, kidney disease. In this way, there...
Time loss injuries compromise team success in Elite Rugby Union

BACKGROUND: A negative association between injuries and team success has been demonstrated in professional football, but the nature of this association in elite Rugby Union teams is currently unclear.

AIM: To assess the...

Facilitating Programme-Level Assessment Working Teams to Develop Shared Rubrics Across a UG and PG Programme Portfolio in Business Education
This chapter is a reflective study reporting on a College-wide common rubrics initiative in a Technological University (TU) in Ireland. Assessment and feedback are enduring issues for the higher education sector both in Ireland...
Bioinspired genotype-phenotype linkages
The idea of compartmentalization of genotype and phenotype in cells is key for enabling Darwinian evolution. This contribution describes bioinspired systems that use in vitro compartments-water-in-oil droplets and gel-shell...

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