Insulin rapidly stimulates GLUT4 translocation and glucose transport in fat and muscle cells. Signals from the occupied insulin receptor are translated into downstream signalling changes in serine/threonine kinases within...
Social media sites employ various approaches to track feelings, including diagnosing neurological problems, including fear, in people or assessing a population public sentiment. One essential obstacle for automatic emotion...
Mahony will begin his duties on July 1, 2015. The President's House will be home to Mahony, his wife Laura and their two children, Gavin, 15, and Elena, 12. Dr. Daniel F. Mahony, dean of the College of Education, Health and...
A study of B+→ J/ψηK+ decays, followed by J/ψ → μ+μ− and η → γγ, is performed using a dataset collected with the LHCb detector in proton-proton collisions at centre-of-mass energies of 7, 8 and 13 TeV, corresponding to an...
V(D)J recombination is essential for the generation of diverse antigen receptor (AgR) repertoires. In B cells, immunoglobulin kappa (Igκ) light chain recombination follows immunoglobulin heavy chain (Igh) recombination. We...
A study of $B_c^+\to J/\psi D_s^+$ and $B_c^+\to J/\psi D_s^{*+}$ decays
using 139 fb$^{-1}$ of integrated luminosity collected with the ATLAS detector
from $\sqrt{s} = 13$ TeV $pp$ collisions at the LHC is presented. The ratios...
In L6 myotubes, redistribution of a hemagglutinin (HA) epitope-tagged GLUT4 (HA-GLUT4) to the cell surface occurs rapidly in response to insulin stimulation and AMP-activated protein kinase (AMPK) activation. We have examined...
The Niemann-Pick disease, type C1 (NPC1) gene encodes a transmembrane protein involved in cholesterol efflux from the lysosome. SNPs within NPC1 have been associated with obesity and type 2 diabetes, and mice heterozygous or...
AIMS/HYPOTHESIS: The glucose transporter GLUT4 is present mainly in insulin-responsive tissues of fat, heart and skeletal muscle and is translocated from intracellular membrane compartments to the plasma membrane (PM) upon...
A study of $B^+ \rightarrow J/\psi \eta K^+$ decays, followed by $J/\psi
\rightarrow \mu^+ \mu^-$ and $\eta \rightarrow \gamma \gamma$, is performed
using a dataset collected with the LHCb detector in proton-proton collisions...
Akt plays a major role in insulin regulation of metabolism in muscle, fat, and liver. Here, we show that in 3T3-L1 adipocytes, Akt operates optimally over a limited dynamic range. This indicates that Akt is a highly sensitive...
Daniel Mayer, leadership educator and researcher into the epistemology of biology, has long reflected on the nature of organization, both of organisms and of organizations. This is the topic of his recently completed PhD...
Abstract: A measurement of the production of a prompt J/ψ meson in association with a W± boson with W± → μν and J/ψ → μ+μ− is presented for J/ψ transverse momenta in the range 8.5–150 GeV and rapidity |yJ/ψ| < 2.1 using ATLAS...
Abstract: A measurement of the production of a prompt J/ψ meson in association with a W± boson with W± → μν and J/ψ → μ+μ− is presented for J/ψ transverse momenta in the range 8.5–150 GeV and rapidity |yJ/ψ| < 2.1 using ATLAS...
Insulin resistance is a pathophysiological state defined by impaired responses to insulin and is a risk factor for several metabolic diseases, most notably type 2 diabetes. Insulin resistance occurs in insulin target tissues...
Abstract: The decays Bs0 → J/ψπ+π−K+K− are studied using a data set corresponding to an integrated luminosity of 9 fb−1, collected with the LHCb detector in proton-proton collisions at centre-of-mass energies of 7, 8 and 13 TeV....
A critical feature of obesity is enhanced insulin secretion from pancreatic β-cells, enabling the majority of individuals to maintain glycaemic control despite adiposity and insulin resistance. Surprisingly, the factors...
Abstract: The decays Bs0 → J/ψπ+π−K+K− are studied using a data set corresponding to an integrated luminosity of 9 fb−1, collected with the LHCb detector in proton-proton collisions at centre-of-mass energies of 7, 8 and 13 TeV....
BACKGROUND & AIMS: Plasma concentrations of bilirubin, a product of heme catabolism formed by biliverdin reductase A (BVRA), inversely associate with the risk of metabolic diseases including hepatic steatosis and diabetes...
Abstract: The decays B+→ J/ψπ+π−K+ are studied using a data set corresponding to an integrated luminosity of 9 fb−1 collected with the LHCb detector in proton-proton collisions between 2011 and 2018. Precise measurements of the...
Abstract: The decays B+→ J/ψπ+π−K+ are studied using a data set corresponding to an integrated luminosity of 9 fb−1 collected with the LHCb detector in proton-proton collisions between 2011 and 2018. Precise measurements of the...