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In vitro model for predicting bioavailability of subcutaneously injected monoclonal antibodies
Hanne Kinnunen Bown, Catherine Bonn, Stefan T. Yohe, Daniela Bumbaca Yadav, Thomas W. Patapoff, Ann L. Daugherty, Randall J. Mrsny
Mar 10, 2018
Monoclonal antibodies (mAbs), which are now more frequently administered by subcutaneous (SC) injection rather than intravenously, have become a tremendously successful drug format across a wide range of therapeutic areas....
In vitro model for predicting bioavailability of subcutaneously injected monoclonal antibodies
Hanne Kinnunen Bown, Catherine Bonn, Stefan T. Yohe, Daniela Bumbaca Yadav, Thomas W. Patapoff, Ann L. Daugherty, Randall J. Mrsny
Mar 10, 2018
Monoclonal antibodies (mAbs), which are now more frequently administered by subcutaneous (SC) injection rather than intravenously, have become a tremendously successful drug format across a wide range of therapeutic areas....
Terzyme
Published by: Plant methods
Two Problem Formulations for Process Innovation Based on Operations Sophistication
Process innovation is assumed to require a more intrinsic rethinking of business processes, which is typically a creative process. Nevertheless, in this creative, prolific process, there can be artifacts derived from rational...
Published by: IGI Global Scientific Publishing
Applications of Mechatronics in Textiles and Clothing Industries
This article focuses on the transformative potential of mechatronics in up-to-date textiles and clothing industries, with a special focus on its implications for automation, efficiency in production, and product quality....
Published by: IGI Global Scientific Publishing
Transferring cognitive talent across domains to reduce the disposition effect in investment.
We consider Theory of Mind (ToM), the ability to correctly predict the intentions of others. To an important degree, good ToM function requires abstraction from one's own particular circumstances. Here, we posit that such...
KIXBASE
The KIX domain has emerged in the last two decades as a critical site of interaction for transcriptional assembly, regulation and gene expression. Discovered in 1994, this conserved, triple helical globular domain has been...
Exploring Digital Agility and Digital Transformation Leadership
This study aims to explore and examine an integrated model predicting digital agility in higher education institutions. In the exploratory phase, semi-structured interviews were conducted with the heads of the institutions to...
Published by: IGI Global Scientific Publishing
Developing Critical Digital Literacies Through Digital Storytelling
The South African Higher Education sector has undergone major transformation since the end of Apartheid more than 25 years ago. Critical digital literacies and critical (digital) citizenship, aligns with the most important...
Published by: IGI Global Scientific Publishing
3D MIMO Beamforming Using Spatial Distance SVM Algorithm and Interference Mitigation for 5G Wireless Communication Network
In recent decades, Multiple Input Multiple Output beamforming is deliberated as the vital technology enablers for 5G mobile radio services. Since, it provides noticeable improvement regarding throughput and coverage measures in...
Published by: IGI Global Scientific Publishing
A Novel Power-Efficient Data Aggregation Scheme for Cloud-Based Sensor Networks
Nowadays sensor nodes are being deployed anywhere as per the applications and real-time data analysis. A major concern of this implementation is the limited battery power and huge data generation. The data redundancy can also...
Published by: IGI Global Scientific Publishing
Improving Organizational Sustainable Performance of Organizations Through Green Training
It is necessary to equip employees with green abilities as well as to develop their dedication towards green behaviour, in order to improve an organization's environmental performance. The purpose of this research is to evaluate...
Published by: IGI Global Scientific Publishing
Laura Chuhan Campbell, The Medieval Merlin Tradition in France and Italy: Prophecy, Paradox, and “Translatio”. (Gallica.) Cambridge, UK: D. S. Brewer, 2017. Pp. viii, 211. £60. ISBN
Irène Fabry-Tehranchi
Feb 07, 2020
This book, a revised version of the author’s 2011 dissertation at the University of Durham, studies the reinterpretation of Merlin’s character in French and Italian Arthurian literature through the question of translation. Laura...
A Hybrid Integration of PLS-SEM, AHP, and FAHP Methods to Evaluate the Factors That Influence the Use of an LMS
The development of learning management systems (LMS) has an integral role to the promotion of new alternatives in relation to improve teaching and learning for universities. This study proposes the determination of the...
Published by: IGI Global Scientific Publishing
Real-time modelling of a pandemic influenza outbreak.
BACKGROUND: Real-time modelling is an essential component of the public health response to an outbreak of pandemic influenza in the UK. A model for epidemic reconstruction based on realistic epidemic surveillance data has been...
StAR-Related Lipid Transfer (START) Domains Across the Rice Pangenome Reveal How Ontogeny Recapitulated Selection Pressures During Rice Domestication.
The StAR-related lipid transfer (START) domain containing proteins or START proteins, encoded by a plant amplified family of evolutionary conserved genes, play important roles in lipid binding, transport, signaling, and...
Hydrophobicity effects in iron polypyridyl complex electrocatalysis within Nafion thin-film electrodes
Four polypyridyl redox catalysts Fe(bp)3 2+, Fe(ph)3 2+, Fe(dm)3 2+, and Fe(tm)3 2+ (with bp, ph, dm, and tm representing...
Quantification of the plant terpenome
Plant essential oils are complex mixtures of volatile organic compounds, which play indispensable roles in communication, defense, and adaptive evolution. The complete chemical library produced by a plant is referred to as its...
Hydrophobicity effects in iron polypyridyl complex electrocatalysis within Nafion thin-film electrodes
Four polypyridyl redox catalysts Fe(bp)3 2+, Fe(ph)3 2+, Fe(dm)3 2+, and Fe(tm)3 2+ (with bp, ph, dm, and tm representing...
Impact of Coronavirus Outbreaks on Science and Society
A global event such as the COVID-19 crisis presents new, often unexpected responses that are fascinating to investigate from both scientific and social standpoints. Despite several documented similarities, the coronavirus...
A Survey on Fatigue Detection of Workers Using Machine Learning
In the software industry, where the quality of the output is based on human performance, fatigue can be a reason for performance degradation. Fatigue not only degrades quality, but is also a health risk factor. Sleep disorders...
Published by: IGI Global Scientific Publishing
Study of Predictors of Organizational Effectiveness Among Private and Public Sector IT Companies
Human relations experts have shown tremendous interest in determining the variables that enhance workers' satisfaction and their loyalty to organisation because only committed and qualified personnel can facilitate the...
Published by: IGI Global Scientific Publishing
Plasmodesmata-mediated intercellular signaling during plant growth and development.
Plasmodesmata (PD) are cytoplasmic channels that connect neighboring cells for cell-to-cell communication. PD structure and function vary temporally and spatially to allow formation of symplastic domains during different stages...
Genetic algorithm assisted multiscale modeling of grain boundary segregation of Al in ZnO and its correlation with nominal dopant concentration
Grain boundary (GB) segregation of Al in ZnO plays an important role in lowering its thermal conductivity for thermoelectric applications. However, the effect of Al concentration on the GB complexions and their transition is...
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