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Lipopolysaccharide activates microglia via neuraminidase 1 desialylation of Toll-like Receptor 4.
Most cell surface receptors are sialylated, i.e. have sialic acid as the terminal residue of their sugar chains, but can be desialylated by sialidases, such as neuraminidase 1 (Neu1). Desialylation by Neu1 can activate immune...
Interview with David Boone - OH 677
This interview was conducted by Dr. George Garrison with Brother David Boone for his Emmett Scott High School history project. Emmett Scott High School was the segregated high school for African-Americans, which was named after...
Published by: Winthrop University
Hans Kindler, Maestro, Feb. 10, 1947
Winthrop News Service
Jan 01, 0001
Hans Kindler will conduct the National Symphony Orchestra at Winthrop auditorium at 8 pm on Friday night.
The orchestra is in its sixteenth season.
This will be the seventh event in the artist series at Winthrop College in the...
Published by: Winthrop University
Be Personal, Not Perfect--A Special Guest Column from David Schary, PESH
This week, a guest column by David Schary, PESH. David tells us we don't need to be perfect--and that can be a plus. Welcome words in this busy week!
Published by: Winthrop University
Review of The Wooster Group, 1975-1985: Breaking The Rules, by David Savran
David Wohl
Jan 01, 0001
A review of David Savran's book, The Wooster Group, 1975-1985: Breaking The Rules.
Wooster Group David Savran Breaking the Rules Arts and Humanities Performance Studies Theatre and Performance Studies
Published by: Winthrop University
"Review of The Wooster Group, 1975-1985: Breaking The Rules, by David Savran."
David Wohl
Jan 01, 0001
A Review of David Savran's The Wooster Group, 1975-1987: Breaking the Rules
Wooster Group Savran Breaking the Rules Arts and Humanities Performance Studies Theatre and Performance Studies
Published by: Winthrop University
David Baltimore, 1975
The Rockefeller University
Jan 01, 0001
David Baltimore. The strategy of RNA viruses
Lecture delivered January 16, 1975
Posted with permission
Published by: Academic Press
Hans Asperger: Held oder Bösewicht
Sarah Wonsidler
Jan 01, 0001
Hans Asperger war ein österreichischer Kinderarzt, Professor, und medizinischer Theoretiker bekannt für seinen Forschung über Autismus in Kindern. W?hrend des Zweiten Welt Kriegs und des Aufstiegs des Nationalsozialisus in Wien...
Hans Asperger Autismus sozialer Darwinismus Eugenik Bewegung am Spiegelgrund Herwig Czech Edith Scheffer Arts and Humanities European History German Language and Literature Holocaust and Genocide Studies Other Medical Sciences
Published by: Ursinus College
Neu1 Is Released From Activated Microglia, Stimulating Microglial Phagocytosis and Sensitizing Neurons to Glutamate
Neuraminidase 1 (Neu1) hydrolyses terminal sialic acid residues from glycoproteins and glycolipids, and is normally located in lysosomes, but can be released onto the surface of activated myeloid cells and microglia. We report...
David Hume, Adam Smith, and William Hamilton of Bangour
Felix Waldmann
Jan 10, 2019
National Library of Scotland, MS 23159.7 is a thirty-two line poem in the hand of David Hume (1711–76), the philosopher. The poem is conserved within a collection of manuscripts devised to the Royal Society of Edinburgh in 1838...
91st Anniversary of David Bancroft Johnson Jan. 10, 1947
Winthrop News Service
Jan 01, 0001
Winthrop College students and faculty will celebrate the 91st birthday of Dr. David Bancroft Johnson, Winthrop College's founder. Dr. Johnson was president of Winthrop Training School for Teachers until his death in 1928.
Published by: Winthrop University
David Horth to Deliver Next ICE Lecture on Feb. 22
Winthrop University
Jan 01, 0001
The next round of the Innovate, Create, Engage (ICE) program's lecture series begins Monday, Feb. 22, with David Horth. Horth is a senior fellow and senior designer with the Center for Creative Leadership in Greensboro, North...
Published by: Winthrop University
Sialylation and Galectin-3 in Microglia-Mediated Neuroinflammation and Neurodegeneration
Microglia are brain macrophages that mediate neuroinflammation and contribute to and protect against neurodegeneration. The terminal sugar residue of all glycoproteins and glycolipids on the surface of mammalian cells is...
Corrections to: Use of the BOADICEA Web Application in clinical practice
Anne Brédart, Jean-Luc Kop, Antonis C Antoniou, Alex P Cunningham, Antoine de Pauw, Marc Tischkowitz, Hans Ehrencrona, Sylvie Dolbeault, Léonore Robieux, Kerstin Rhiem, Douglas F Easton, Peter Devilee, Dominique Stoppa-Lyonnet, Rita Schmutlzer
Jan 23, 2018
The article "Use of the BOADICEA Web Application in clinical practice: appraisals by clinicians from various countries" written by Anne Brédart · Jean‑Luc Kop · Antonis C. Antoniou · Alex P. Cunningham · Antoine De Pauw ·Marc...
David Meeler Tapped as Dalton Endowed Chair of Environmental Sciences and Studies
Winthrop University
Jan 01, 0001
David Meeler is only the second faculty member to hold this position in its 13 years of existence. Winthrop's environmental program crosses several disciplinary departments, something Meeler feels comfortable doing.
Published by: Winthrop University
David Loewenstein. Treacherous Faith: The Specter of Heresy in Early Modern English Literature and Culture. Oxford: Oxford UP, 2013. xiv + 497pp. ISBN 13
David L Smith
May 08, 2019
This is an important, original, and deeply researched book. David Loewenstein's purpose is to explore the ways in which early modern English authors constructed the phenomena of heretics and heresies, and the profound religious...
Pulitzer Prize-Winning Reporter David Fahrenthold to Speak at Winthrop on Feb. 19
Winthrop University
Jan 01, 0001
HIGHLIGHTS Fahrenthold broke some of the most talked-about stories of the presidential campaign in 2016, including pieces on the Trump foundation and the "Access Hollywood" video. He now covers the Trump family and its business...
Published by: Winthrop University
Sialylation acts as a checkpoint for innate immune responses in the central nervous system.
Sialic acids are monosaccharides that normally terminate the glycan chains of cell surface glyco-proteins and -lipids in mammals, and are highly enriched in the central nervous tissue. Sialic acids are conjugated to proteins and...
Gambling on Europe
Julie Smith
Feb 16, 2018
Membership of the European Union has devided British political parties for decades. On taking office David Cameron hoped to move his Conservative Party beyond the electorally rather unwelcome focus on ‘Europe’. By 2013 he felt...
Map of Labrador
David Mercer
Apr 24, 2014
Map of Labrador showing communities relevant to theis issue of RLS and more recently established communities. Prepared by David Mercer, Library Assistant, Map Room, QEII Library, Memorial University.
Published by: Memorial University of Newfoundland
Microglial phagocytosis of neurons in neurodegeneration, and its regulation.
Claire A Butler, Alma S Popescu, Emily JA Kitchener, David H Allendorf, Mar Puigdellívol, Guy C Brown
Mar 02, 2021
There is growing evidence that excessive microglial phagocytosis of neurons and synapses contributes to multiple brain pathologies. RNA-seq and genome-wide association (GWAS) studies have linked multiple phagocytic genes to...
Sound human, steer clear of jargon, and be prepared.
Kevin McConway and David Spiegelhalter offer tips to statisticians communicating through the media, especially in the time of Covid-19.
Map of Labrador
David Mercer
Apr 24, 2014
Map of Labrador showing communities relevant to theis issue of RLS and more recently established communities. Prepared by David Mercer, Library Assistant, Map Room, QEII Library, Memorial University.
Published by: Memorial University of Newfoundland
Britain, Britishness, and exceptionalism within the rhetoric of David Cameron
Michael Bolt
Mar 31, 2023
In his rhetoric on Britain and Britishness, David Cameron sets out a vision of the nation and its national story built upon the premise of exceptionalism. I argue this was challenging to reconcile with continued EU membership....
Britain British political speech Britishness David Cameron exceptionalism Rhetorical political analysis /dk/atira/pure/subjectarea/asjc/1200/1202 name=History /dk/atira/pure/subjectarea/asjc/3300/3320 name=Political Science and International Relations /dk/atira/pure/subjectarea/asjc/3300/3312 name=Sociology and Political Science
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