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Results: 169
Aβ efflux impairment and inflammation linked to cerebrovascular accumulation of amyloid-forming amylin secreted from pancreas.
Nirmal Verma, Gopal Viswanathan Velmurugan, Edric Winford, Han Coburn, Deepak Kotiya, Noah Leibold, Laura Radulescu, Sanda Despa, Kuey C Chen, Linda J Van Eldik, Peter T Nelson, Donna M Wilcock, Gregory A Jicha, Ann M Stowe, Larry B Goldstein, David K Powel, Jeffrey H Walton, Manuel F Navedo, Matthew A Nystoriak, Andrew J Murray, Geert Jan Biessels, Claire Troakes, Henrik Zetterberg, John Hardy, Tammaryn Lashley, Florin Despa
Jan 04, 2023
The association of circulating amylin with β-amyloid in familial Alzheimer's disease.
Han Ly, Nirmal Verma, Savita Sharma, Deepak Kotiya, Sanda Despa, Erin L Abner, Peter T Nelson, Gregory A Jicha, Donna M Wilcock, Larry B Goldstein, Rita Guerreiro, José Brás, Angela J Hanson, Suzanne Craft, Andrew J Murray, Geert Jan Biessels, Claire Troakes, Henrik Zetterberg, John Hardy, Tammaryn Lashley, Aesg, Florin Despa
Feb 19, 2021
INTRODUCTION: This study assessed the hypothesis that circulating human amylin (amyloid-forming) cross-seeds with amyloid beta (Aβ) in early Alzheimer's disease (AD). METHODS: Evidence of amylin-AD pathology interaction was...
A Hybridized Deep Learning Strategy for Course Recommendation
Recommender systems have been actively used in many areas like e-commerce, movie and video suggestions, and have proven to be highly useful for its users. But the use of recommender systems in online learning platforms is often...
Published by: IGI Global Scientific Publishing
Phish-Shelter
Phishing attack is a deceitful attempt to steal the confidential data such as credit card information, and account passwords. In this paper, Phish-Shelter, a novel anti-phishing browser is developed, which analyzes the URL and...
Published by: IGI Global Scientific Publishing
Web Bot Detection System Based on Divisive Clustering and K-Nearest Neighbor Using Biostatistics Features Set
Web bots are destructive programs that automatically fill the web form and steal the data from web sites. According to numerous web bot traffic reports, web bots traffic comprises of more than fifty percent of the total web...
Published by: IGI Global Scientific Publishing
AI and Database Management for Organizational Transformation With Insights From Twitter Data
This paper explores the role of AI and database management in organizational transformation using insights from Twitter data. By analyzing 30,000 English-language tweets with methods such as word analysis, topic modeling...
Published by: IGI Global Scientific Publishing
Composite Measures for Clinical Trials in Psoriatic Arthritis
OBJECTIVE: To test the addition of pain and fatigue to the Composite Psoriatic Arthritis Disease Activity (CPDAI) and the Group for Research and Assessment of Psoriasis and PsA (GRAPPA) Composite Exercise (GRACE) composite...
Alternated Superior Chaotic Biogeography-Based Algorithm for Optimization Problems
In this study, we consider a switching strategy that yields a stable desirable dynamic behaviour when it is applied alternatively between two undesirable dynamical systems. From the last few years, dynamical systems employed...
Published by: IGI Global Scientific Publishing
Aβ efflux impairment and inflammation linked to cerebrovascular accumulation of amyloid-forming amylin secreted from pancreas.
Nirmal Verma, Gopal Viswanathan Velmurugan, Edric Winford, Han Coburn, Deepak Kotiya, Noah Leibold, Laura Radulescu, Sanda Despa, Kuey C Chen, Linda J Van Eldik, Peter T Nelson, Donna M Wilcock, Gregory A Jicha, Ann M Stowe, Larry B Goldstein, David K Powel, Jeffrey H Walton, Manuel F Navedo, Matthew A Nystoriak, Andrew J Murray, Geert Jan Biessels, Claire Troakes, Henrik Zetterberg, John Hardy, Tammaryn Lashley, Florin Despa
Feb 09, 2023
Multidisciplinary working in the management of axial and peripheral spondyloarthritis.
Multidisciplinary (MD) care is essential in the management of patients with spondyloarthritis (SpA) and is one of the main pillars of disease management and patient care. However, evidence supporting the effectiveness and...
Composite Measures for Routine Clinical Practice in Psoriatic Arthritis
OBJECTIVE: To test shortened versions of the psoriatic arthritis (PsA) composite measures for use in routine clinical practice.
METHODS: Clinical and patient-reported outcome measures (PROMs) were assessed in patients...
Modelling of Seismic Liquefaction Using Classification Techniques
Liquefaction susceptibility of soil is a complex problem due to non-linear behaviour of soil and its physical attributes. The assessment of liquefaction potential is commonly assessed by the in-situ testing methods. The...
Published by: IGI Global Scientific Publishing
Intrusion Detection System for IoE-Based Medical Networks
Internet of everything (IoE) has the power of reforming the healthcare sector - various medical devices, hardware, and software applications that are interconnected, tendering a massive volume of data. The huge interconnected...
Published by: IGI Global Scientific Publishing
Mobile Cloud Forensic Readiness Process Model for Cloud-Based Mobile Applications
Nowadays, mobile cloud applications have attracted millions of smartphone users due to the proliferation of cyber technologies and a wide range of applications. Mobile cloud forensic investigation methodologies need tremendous...
Published by: IGI Global Scientific Publishing
Cardiac Arrhythmia, CHF, and NSR Classification With NCA-Based Feature Fusion and SVM Classifier
An arrhythmia is an irregular heartbeat that causes abnormal heart rhythms. Manual analysis of electrocardiogram (ECG) signals is not sufficient to quickly detect cardiac arrhythmias. This study proposes a deep learning approach...
Systems & Software Design Computer Science and Information Technology Systems and Software Engineering
Published by: IGI Global Scientific Publishing
A comparison of clinical examination and ultrasound enthesitis indices in patients with psoriatic arthritis, adjusted for concomitant fibromyalgia
Objectives:: To: (a) determine the extent of ultrasound (US)-detected peripheral enthesitis in a cohort of patients with psoriatic arthritis (PsA); (b) compare this with three clinical examination (CE) enthesitis indices; and...
A Liquefaction Study Using ENN, CA, and Biogeography Optimized-Based ANFIS Technique
In any construction projects,assessment of liquefaction potential induced due to seismic excitation during earthquake is a critical concern.The objective of present model development is to classify and assess liquefaction...
Published by: IGI Global Scientific Publishing
Novel Composite Radiographic Score for Longitudinal Observational Studies of Psoriatic Arthritis
William Tillett, Gavin Shaddick, Deepak Jadon, Graham Robinson, Eleanor Korendowych, Neil McHugh
Jan 15, 2016
OBJECTIVE: To devise a feasible composite radiographic score for use in observational studies of psoriatic arthritis (PsA).
METHODS: Radiographs from 50 patients with PsA were evaluated with the PsA-modified Sharp...
Virus-Induced Maternal Immune Activation as an Environmental Factor in the Etiology of Autism and Schizophrenia.
Maternal immune activation (MIA) is mediated by activation of inflammatory pathways resulting in increased levels of cytokines and chemokines that cross the placental and blood-brain barriers altering fetal neural development....
PNTRS
A news recommendation system not only must recommend the latest, trending, and personalized news to the users but also give opportunity to know about the people's opinion on trending news. Most of the existing news...
Published by: IGI Global Scientific Publishing
Multidisciplinary working in the management of axial and peripheral spondyloarthritis
Multidisciplinary (MD) care is essential in the management of patients with spondyloarthritis (SpA) and is one of the main pillars of disease management and patient care. However, evidence supporting the effectiveness and...
Composite Measures for Routine Clinical Practice in Psoriatic Arthritis
OBJECTIVE: To test shortened versions of the psoriatic arthritis (PsA) composite measures for use in routine clinical practice.
METHODS: Clinical and patient-reported outcome measures (PROMs) were assessed in patients...
Composite Measures for Clinical Trials in Psoriatic Arthritis
OBJECTIVE: To test the addition of pain and fatigue to the Composite Psoriatic Arthritis Disease Activity (CPDAI) and the Group for Research and Assessment of Psoriasis and PsA (GRAPPA) Composite Exercise (GRACE) composite...
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