Search
Results: 909
Diverse Clinical Isolates of Mycobacterium tuberculosis Develop Macrophage-Induced Rifampin Tolerance.
Kristin N Adams, Amit Kumar Verma, Radha Gopalaswamy, Harresh Adikesavalu, Dinesh Kumar Singhal, Srikanth Tripathy, Uma Devi Ranganathan, David R Sherman, Kevin B Urdahl, Lalita Ramakrishnan, Rafael E Hernandez
Jan 28, 2019
The Mycobacterium tuberculosis lineage 4 strains CDC1551 and H37Rv develop tolerance to multiple antibiotics upon macrophage residence. To determine whether macrophage-induced tolerance is a general feature of clinical M....
Rv1258c Beijing lineage Tuberculosis antibiotic tolerance drug efflux ATP-Binding Cassette Transporters Antitubercular Agents Bacterial Proteins Drug Resistance Multiple Bacterial Humans Isoniazid Loss of Function Mutation MACROPHAGES Microbial Sensitivity Tests Mycobacterium tuberculosis Rifampin THP-1 Cells Tuberculosis Multidrug-Resistant
Anti-thrombotic efficacy of S007-867
Ankita Misra, Prem Prakash, Hobby Aggarwal, Priyanka Dhankani, Sachin Kumar, Chandra Prakash Pandey, Nicholas Pugh, Dominique Bihan, Manoj Kumar Barthwal, Richard W Farndale, Dinesh Kumar Dikshit, Madhu Dikshit
Mar 15, 2018
Pharmacological inhibition of platelet collagen interaction is a promising therapeutic strategy to treat intra-vascular thrombosis. S007-867 is a novel synthetic inhibitor of collagen-induced platelet aggregation. It has shown...
Blood Flow Velocity Collagen Hemostasis Platelet Activation Thrombosis Animals Aspirin Blood Coagulation Chlorides Clopidogrel Dose-Response Relationship Drug Ferric Compounds Fibrinolytic Agents Male Mice Piperidines Platelet Adhesiveness Platelet Aggregation Pyrrolidines Rats Rats Sprague-Dawley Thrombosis
ICT Use and Its Influence in Family Functioning With Reference to Process and Structure of Families
ICT use in family functioning is an important area to study as the impact changes when technology grows over years. This research analyzed the role of ICT use in process & structure of families using the factors present in...
Published by: IGI Global Scientific Publishing
A Modified GA-Based Load Balanced Clustering Algorithm for WSN
The prevalent applications of WSN have fascinated a plethora of research efforts. Sensor nodes have serious limitations such as battery lifetime, memory constraints, and computational capabilities. Clustering is an important...
Published by: IGI Global Scientific Publishing
Fine Tuning CNN for COVID-19 Patterns Detection From Chest Radiographs
The COVID-19 pandemic has crumbled health systems all over the world. Quick and accurate detection of coronavirus infection plays an important role in timely referral of physicians and control transmission of the disease. RT-PCR...
Published by: IGI Global Scientific Publishing
Prediction of Piezoelectric Tile Performance in Flat and Mountainous Terrains Through Deep Neural Network
Jitendra Adhikari, Kamalpreet Singh, Anjani Kumar Sagar, Vikki Kumar Sharma, Rajeev Kumar, Satish Chandra Jain
Sep 13, 2023
Piezoelectric tiles harvest mechanical vibrations and convert them into electrical energy, making them an attractive energy-harvesting technology. However, their performance is heavily influenced by the terrain where they are...
PSK Method for Solving Mixed and Type-4 Intuitionistic Fuzzy Solid Transportation Problems
P. Kumar
Apr 01, 2019
In this article, the author categorises the solid transportation problem (STP) under uncertain environments. He formulates the mixed and fully intuitionistic fuzzy solid transportation problems (FIFSTPs) and utilizes the...
Published by: IGI Global Scientific Publishing
Prediction of Piezoelectric Tile Performance in Flat and Mountainous Terrains Through Deep Neural Network
Jitendra Adhikari, Kamalpreet Singh, Anjani Kumar Sagar, Vikki Kumar Sharma, Rajeev Kumar, Satish Chandra Jain
Sep 13, 2023
Piezoelectric tiles harvest mechanical vibrations and convert them into electrical energy, making them an attractive energy-harvesting technology. However, their performance is heavily influenced by the terrain where they are...
Neutronic investigation of alternative & composite burnable poisons for the soluble-boron-free and long life civil marine small modular reactor cores.
Syed Bahauddin Alam, Bader Almutairi, Tuhfatur Ridwan, Dinesh Kumar, Cameron S Goodwin, Kirk D Atkinson, Geoffrey T Parks
Nov 27, 2019
Concerns about the effects of global warming provide a strong case to consider how best nuclear power could be applied to marine propulsion. Currently, there are persistent efforts worldwide to combat global warming, and that...
Effect of exposure to cleaning agents on pulmonary function tests in hospital cleaning workers in Jaipur
Cleaning products are widely used both at work and in the home. These products have become an indispensable part of modern life, as they are used on daily basis in nearly all workplaces and homes Occupational exposure to...
Published by: IJHS Medical Association
Analysis of mutations in pncA reveals non-overlapping patterns among various lineages of Mycobacterium tuberculosis
Abstract Pyrazinamide (PZA) is an important first-line anti-tuberculosis drug, resistance to which occurs primarily due to mutations in pncA ...
Ramani Baddam, Narender Kumar, Lothar H Wieler, Aditya Kumar Lankapalli, Niyaz Ahmed, Sharon J Peacock, Torsten Semmler
May 30, 2018
Amyloidogenic proteins in the SARS-CoV and SARS-CoV-2 proteomes.
Neutronic investigation of alternative & composite burnable poisons for the soluble-boron-free and long life civil marine small modular reactor cores.
Syed Bahauddin Alam, Bader Almutairi, Tuhfatur Ridwan, Dinesh Kumar, Cameron S Goodwin, Kirk D Atkinson, Geoffrey T Parks
Jan 27, 2020
Concerns about the effects of global warming provide a strong case to consider how best nuclear power could be applied to marine propulsion. Currently, there are persistent efforts worldwide to combat global warming, and that...
Effect of exposure to cleaning agents on pulmonary function tests in hospital cleaning workers in Jaipur
Cleaning products are widely used both at work and in the home. These products have become an indispensable part of modern life, as they are used on daily basis in nearly all workplaces and homes Occupational exposure to...
Published by: IJHS Medical Association
Analysis of mutations in pncA reveals non-overlapping patterns among various lineages of Mycobacterium tuberculosis.
Ramani Baddam, Narender Kumar, Lothar H Wieler, Aditya Kumar Lankapalli, Niyaz Ahmed, Sharon J Peacock, Torsten Semmler
Sep 26, 2018
Pyrazinamide (PZA) is an important first-line anti-tuberculosis drug, resistance to which occurs primarily due to mutations in pncA (Rv2043c) that encodes the pyrazinamidase enzyme responsible for conversion of pro-drug PZA into...
Efficient One-Pot Solvothermal Synthesis and Characterization of Zirconia Nanoparticle-Decorated Reduced Graphene Oxide Nanocomposites
Nalinee Kanth Kadiyala, Badal Kumar Mandal, L Vinod Kumar Reddy, Crispin HW Barnes, Luis De Los Santos Valladares, Dwaipayan Sen
Feb 23, 2023
This study mainly deals with an effective one-pot solvothermal synthetic pathway for the preparation of uniformly dispersed zirconium oxide nanoparticles on the flattened rough surface of reduced graphene oxide (ZrO2/rGO NCs)...
Chromatin Accessibility Impacts Transcriptional Reprogramming in Oocytes.
Kei Miyamoto, Khoi T Nguyen, George E Allen, Jerome Jullien, Dinesh Kumar, Tomoki Otani, Charles R Bradshaw, Frederick J Livesey, Manolis Kellis, John B Gurdon
Oct 10, 2018
Oocytes have a remarkable ability to reactivate silenced genes in somatic cells. However, it is not clear how the chromatin architecture of somatic cells affects this transcriptional reprogramming. Here, we investigated the...
nuclear transfer open chromatin reprogramming Transcriptional Activation Animals Cellular Reprogramming Chromatin FIBROBLASTS Mice Oocytes Promoter Regions Genetic Sequence Analysis DNA Transcription Factors Transcription Initiation Site Transcription Genetic Transcriptional Activation Transposases Xenopus laevis
IR Laser-Induced Gene Expression for Tracking Development of Single Embryonic Neurons and Glia in C. Elegans
Anupriya Singhal
Jan 01, 0001
The assembly of neural circuits requires a complex choreography of developmental events: neurons must be generated, extend neurites at the correct time and location, and then integrate extracellular information, like long-range...
Published by: Rockefeller University
Nanobubbles in water and wastewater treatment systems
Mingyi Jia, Muhammad Usman Farid, Jehad A. Kharraz, Nallapaneni Manoj Kumar, Shauhrat S. Chopra, Am Jang, John Chew, Samir Kumar Khanal, Guanghao Chen, Alicia An
Oct 15, 2023
Since the discovery of nanobubbles (NBs) in 1994, NBs have been attracting growing attention for their fascinating properties and have been studied for application in various environmental fields, including water and wastewater...
Identifying the Factors Associated With Inpatient Admissions for Non-COVID-19 Illnesses
Declining inpatient admissions have serious consequences on hospital financial stability as well as the health of patients. Thus, identifying factors associated with inpatient admissions is crucial to properly manage healthcare...
Published by: IGI Global Scientific Publishing
Biogenic Photo-Catalyst TiO2 Nanoparticles for Remediation of Environment Pollutants.
Boya Palajonnala Narasaiah, Pravallika Banoth, Angel Guillermo Bustamante Dominguez, Badal Kumar Mandal, Challa Kiran Kumar, Crispin HW Barnes, Luis De Los Santos Valladares, Pratap Kollu
Sep 07, 2022
This article reports a benign environmentally friendly fabrication method of titanium dioxide (TDO) nanoparticles (named TDO NPs3, TDO NPs5, and TDO NPs8) using aqueous extract of durva herb waste. This synthesis process avoids...
Amyloidogenic proteins in the SARS-CoV and SARS-CoV-2 proteomes.
Taniya Bhardwaj, Kundlik Gadhave, Shivani K Kapuganti, Prateek Kumar, Zacharias Faidon Brotzakis, Kumar Udit Saumya, Namyashree Nayak, Ankur Kumar, Richa Joshi, Bodhidipra Mukherjee, Aparna Bhardwaj, Krishan Gopal Thakur, Neha Garg, Michele Vendruscolo, Rajanish Giri
Mar 24, 2023
The phenomenon of protein aggregation is associated with a wide range of human diseases. Our knowledge of the aggregation behaviour of viral proteins, however, is still rather limited. Here, we investigated this behaviour in the...
Animals Mammals Humans Proteome Amyloidogenic Proteins covid-19 SARS-CoV-2 Severe acute respiratory syndrome-related coronavirus
Published by: Nature Communications
Efficient One-Pot Solvothermal Synthesis and Characterization of Zirconia Nanoparticle-Decorated Reduced Graphene Oxide Nanocomposites
Nalinee Kanth Kadiyala, Badal Kumar Mandal, L Vinod Kumar Reddy, Crispin HW Barnes, Luis De Los Santos Valladares, Dwaipayan Sen
Jan 18, 2023
This study mainly deals with an effective one-pot solvothermal synthetic pathway for the preparation of uniformly dispersed zirconium oxide nanoparticles on the flattened rough surface of reduced graphene oxide (ZrO2/rGO NCs)...
Nanobubbles in water and wastewater treatment systems
Mingyi Jia, Muhammad Usman Farid, Jehad A. Kharraz, Nallapaneni Manoj Kumar, Shauhrat S. Chopra, Am Jang, John Chew, Samir Kumar Khanal, Guanghao Chen, Alicia An
Oct 15, 2023
Since the discovery of nanobubbles (NBs) in 1994, NBs have been attracting growing attention for their fascinating properties and have been studied for application in various environmental fields, including water and wastewater...
|
|< |
< |
1 |