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Imperfect integration
Decision-making on the basis of multiple information sources is common. However, to what extent such decisions differ from those with a single source remains unclear. We combined cognitive modelling and neural-mass modelling to...
Experimental Investigation of Ion Formation for Auto-Ignition Combustion in a High-Temperature and High-Pressure Combustion Vessel
One of the main challenges in internal combustion engine design is the simultaneous reduction of all engine pollutants like carbon monoxide (CO), total unburned hydrocarbons (THC), nitrogen oxides (NOx), and soot....
Understanding Cryptocurrency
This exploratory applied study examines the nature and dimensions of cryptocurrency, namely bitcoin, a peer-to-peer network for facilitating digital barter. As the most widely used cryptocurrency, bitcoin has carved itself a...
Published by: IGI Global Scientific Publishing
Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis
Dominik Trzupek, Melanie Dunstan, Antony J. Cutler, Mercede Lee, Leila Godfrey, Lorna Jarvis, Daniel B. Rainbow, Dominik Aschenbrenner, Joanne L. Jones, Holm H. Uhlig, Linda S. Wicker, John A. Todd, Ricardo C. Ferreira
Jun 24, 2021
Abstract: Background: Traditionally, the transcriptomic and proteomic characterisation of CD4+ T cells at the single-cell level has been performed by two largely exclusive types of technologies: single-cell RNA sequencing...
A Competency-Based Lens for Exploring Higher Education Opportunities
In the current fast-paced environment, learners want flexibility in timing and content as they seek relevant credentials to be successful. For institutions of higher education (IHEs) to be relevant, they must address the...
Higher Education Education Higher Education Social Sciences and Humanities Library and Information Science
Published by: IGI Global Scientific Publishing
Experimental Investigation of Ion Formation for Auto-Ignition Combustion in a High-Temperature and High-Pressure Combustion Vessel
One of the main challenges in internal combustion engine design is the simultaneous reduction of all engine pollutants like carbon monoxide (CO), total unburned hydrocarbons (THC), nitrogen oxides (NOx), and soot....
The feet in human--computer interaction
Foot-operated computer interfaces have been studied since the inception of human--computer interaction. Thanks to the miniaturisation and decreasing cost of sensing technology, there is an increasing interest exploring this...
A Semantic File System for Integrated Product Data Management
A mechatronic system is a synergistic integration of mechanical, electrical, electronic and software technologies into electromechanical systems. Unfortunately, mechanical, electrical, and software data are often handled in...
Information Requirements Analysis for Holonic Manufacturing Systems in a Virtual Environment
The design and development of holonic manufacturing systems requires careful, and sometimes risky, decision making to ensure that they will successfully satisfy the demands of an ever-changing market. In this paper, the authors...
Helicase Subunit Cdc45 Targets the Checkpoint Kinase Rad53 to Both Replication Initiation and Elongation Complexes after Fork Stalling.
Across eukaryotes, disruption of DNA replication causes an S phase checkpoint response, which regulates multiple processes, including inhibition of replication initiation and fork stabilization. How these events are coordinated...
Cdc45 DNA Damage DNA Replication Rad53 budding yeast checkpoint replisome Cell Cycle Proteins Checkpoint Kinase 2 Congenital Microtia DNA Damage DNA Repair DNA Replication DNA Fungal DNA-Binding Proteins Growth Disorders Humans Micrognathism Mutation Nuclear Proteins Patella Phosphorylation Protein Binding S Phase Cell Cycle Checkpoints Saccharomyces cerevisiae Saccharomyces cerevisiae Proteins
Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis.
Dominik Trzupek, Melanie Dunstan, Antony J Cutler, Mercede Lee, Leila Godfrey, Lorna Jarvis, Daniel B Rainbow, Dominik Aschenbrenner, Joanne L Jones, Holm H Uhlig, Linda S Wicker, John A Todd, Ricardo C Ferreira
Sep 09, 2020
BACKGROUND: Traditionally, the transcriptomic and proteomic characterisation of CD4+ T cells at the single-cell level has been performed by two largely exclusive types of technologies: single-cell RNA sequencing (scRNA-seq) and...
AbSeq C-C chemokine receptor type 9 (CCR9) CD4+ T cells CD80 CD86 Immunophenotyping multi-omics regulatory T cells (tregs) Single-cell RNA sequencing (scRNA-seq) Adolescent Adult B7-1 Antigen B7-2 Antigen Female Forkhead Transcription Factors Humans Male Proteome RNA RNA-seq Single-Cell Analysis T-Lymphocytes Regulatory Transcriptome
Public good provision and ancillary benefits
Several studies found ancillary benefits of the provision of public goods to be of considerable size. If these additional private benefits were noticed, they would imply not only higher cooperative but also non-cooperative...
Structural and relational interdependence and entrepreneurial orientation in small and medium-sized enterprises
This article examines the intermediary role of internal knowledge-sharing in the relationship between two aspects of small and medium-sized enterprises’ (SMEs) internal organisational context: structural and relational...
Smart manufacturability analysis for digital product development
Cloud-Based Design and Manufacturing is a service-oriented networked product development model in which service consumers are enabled to configure, select and utilize customized product realization services ranging from...
Aligning orthodontic education
INTRODUCTION: General dentists are qualified to manage orthodontic emergencies within their scope of practice. This may involve advice, hands-on intervention or referral to a specialist orthodontist. This study aimed to assess...
When good conflict gets better and bad conflict becomes worse
This research investigates the moderating effect of social capital on the conflict-innovation relationship and poses the argument that social interaction amplifies the beneficial effect of task conflict and the harmful effect of...
Software-defined cloud manufacturing for industry 4.0
Many of the world’s leading industrial nations have invested in national initiatives to foster advanced manufacturing, innovation,and design for the globalized world. Much of this investment has been driven by visions such as...
Perceptions of adverse work conditions and innovative behavior
This study investigates how employees' perceptions of adverse work conditions might discourage innovative behavior and the possible buffering roles of relational resources. Data from a Mexican-based organization reveal that...
An Investigation into Utilizing Current Information Technologies to Provide Engineering Education to Sub-Saharan Africa
Engineering education is one of the key factors for the development of any nation. Nowhere is this
more true than in Sub-Saharan Africa, where a dearth of engineers has contributed to the lowest
regional standard of...
more true than in Sub-Saharan Africa, where a dearth of engineers has contributed to the lowest
regional standard of...
State-of-the-art cooling and lubrication for machining Inconel 718
Inconel 718 is the most used nickel superalloys with applications in aerospace, oil&gas, nuclear and chemical industries. It is mostly used for safety-critical components where the condition of the surface is a significant...
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