Search
Results: 279
3DVL@ES
This paper introduces a virtual laboratory that aims to support the quick development and easy assimilation of practical works by learners and exchange documents between them via a shared virtual space. The proposed laboratory...
Published by: IGI Global Scientific Publishing
Bregman Itoh–Abe Methods for Sparse Optimisation
In this paper we propose optimisation methods for variational regularisation
problems based on discretising the inverse scale space flow with discrete
gradient methods. Inverse scale space flow generalises gradient flows...
A Geometric Integration Approach to Nonsmooth, Nonconvex Optimisation
The optimisation of nonsmooth, nonconvex functions without access to
gradients is a particularly challenging problem that is frequently encountered,
for example in model parameter optimisation problems. Bilevel optimisation...
Validation of a Brief Measure of Aggression for Ecological Momentary Assessment Research
Ecological momentary assessment (EMA) holds significant potential within aggression research. It affords researchers the possibility of collecting data in ecological context, in near real time. However, there is a lack of...
Sox7 is dispensable for primitive endoderm differentiation from mouse ES cells.
BACKGROUND: Primitive endoderm is a cell lineage segregated from the epiblast in the blastocyst and gives rise to parietal and visceral endoderm. Sox7 is a member of the SoxF gene family that is specifically expressed in...
The evolutionally-conserved function of group B1 Sox family members confers the unique role of Sox2 in mouse ES cells.
Hitoshi Niwa, Akira Nakamura, Makoto Urata, Maki Shirae-Kurabayashi, Shigehiro Kuraku, Steven Russell, Satoshi Ohtsuka
Sep 29, 2016
BACKGROUND: In mouse ES cells, the function of Sox2 is essential for the maintenance of pluripotency. Since the Sox-family of transcription factors are well conserved in the animal kingdom, addressing the evolutionary origin of...
A resource of vectors and ES cells for targeted deletion of microRNAs in mice.
The 21-23 nucleotide, single-stranded RNAs classified as microRNAs (miRNA) perform fundamental roles in diverse cellular and developmental processes. In contrast to the situation for protein-coding genes, no public resource of...
The assassination of Eduardo Mondlane
George Roberts
Sep 29, 2018
This article uses the city of Dar es Salaam as an urban lens for understanding the politics of FRELIMO in exile and the assassination of its first president, Eduardo Mondlane, in 1969. By adopting a multiarchival technique...
Large Reductions in Match Play Physical Performance Variables Across a Professional Football Season with Control for Situational and Contextual Variables
This investigation examined match play physical performance across a professional football season using a multicamera computerized tracking system. A linear mixed-effects model, controlling for situational and contextual...
The Ursinus Weekly, February 4, 1910
Paul A. Mertz
Jan 01, 0001
Founders' Day Jacob Riis at Ursinus Valentine fete Dr. Rolfe coming New instructors Going to "Ben Hur" Class officers elected Alumni Repairs taking place Society notes Seminary notes
Ursinus College Collegeville Pennsylvania newspaper William J. Rolfe Bomberger Memorial Hall YMCA YWCA Zwinglian literary society Schaff literary society cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
The Ursinus Weekly, January 28, 1910
Paul A. Mertz
Jan 01, 0001
Day of Prayer Founders' Day Jacob Riis coming Date of May Musical Festival changed Academy notes Deutscher verein Society notes Ursinus hash Letter Resolutions
Ursinus College Collegeville Pennsylvania newspaper YMCA YWCA Zwinglian literary society Schaff literary society cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Wnt/ß-catenin signalling and the dynamics of fate decisions in early mouse embryos and embryonic stem (ES) cells
tWnt/ß-catenin signalling is a widespread cell signalling pathway with multiple roles during vertebrate development. In mouse embryonic stem (mES) cells, there is a dual role for ß-catenin: it promotes differentiation when...
Wnt/ß-catenin signalling and the dynamics of fate decisions in early mouse embryos and embryonic stem (ES) cells
tWnt/ß-catenin signalling is a widespread cell signalling pathway with multiple roles during vertebrate development. In mouse embryonic stem (mES) cells, there is a dual role for ß-catenin: it promotes differentiation when...
Mannosidase 2, alpha 1 deficiency is associated with ricin resistance in embryonic stem (ES) cells.
Wei Wang, Christine Hale, Dave Goulding, Stuart M Haslam, Bérangère Tissot, Christopher Lindsay, Stephen Michell, Rick Titball, Jun Yu, Ana Luisa Toribio, Raffaella Rossi, Anne Dell, Allan Bradley, Gordon Dougan
Oct 14, 2020
Host gene products required for mediating the action of toxins are potential targets for reversing or controlling their pathogenic impact following exposure. To identify such targets libraries of insertional gene-trap mutations...
Robust Optimization-Based Energy Storage Operation for System Congestion Management
Power system operation faces an increasing level of uncertainties from renewable generation and demand, which may cause large-scale congestion under an ineffective operation. This article applies energy storage (ES) to reduce...
A Geometric Integration Approach to Nonsmooth, Nonconvex Optimisation
The optimisation of nonsmooth, nonconvex functions without access to gradients is a particularly challenging problem that is frequently encountered, for example in model parameter optimisation problems. Bilevel optimisation...
A Geometric Integration Approach to Nonsmooth, Nonconvex Optimisation
The optimisation of nonsmooth, nonconvex functions without access to gradients is a particularly challenging problem that is frequently encountered, for example in model parameter optimisation problems. Bilevel optimisation...
Bregman Itoh–Abe Methods for Sparse Optimisation
Abstract: In this paper we propose optimisation methods for variational regularisation problems based on discretising the inverse scale space flow with discrete gradient methods. Inverse scale space flow generalises gradient...
Large Reductions in Match Play Physical Performance Variables Across a Professional Football Season with Control for Situational and Contextual Variables
This investigation examined match play physical performance across a professional football season using a multicamera computerized tracking system. A linear mixed-effects model, controlling for situational and contextual...
LMP-based Pricing for Energy Storage in Local Market to Facilitate PV Penetration
Increasing Photovoltaic (PV) penetration and low-carbon demand can potentially lead to two different flow peaks, generation, and load, within distribution networks. This will not only constrain PV penetration but also pose...
Exome Sequencing for Prenatal Detection of Genetic Abnormalities in Fetal Ultrasound Anomalies
Shahela S Kodabuckus, Elizabeth Quinlan-Jones, Dominic J McMullan, Eamonn R Maher, Matthew E Hurles, Pelham M Barton, Mark D Kilby
Jan 27, 2020
INTRODUCTION: In light of the prospective Prenatal Assessment of Genomes and Exomes (PAGE) study, this paper aimed to determine the additional costs of using exome sequencing (ES) alongside or in place of chromosomal microarray...
REST selectively represses a subset of RE1-containing neuronal genes in mouse embryonic stem cells.
Helle F Jørgensen, Anna Terry, Chiara Beretta, C Filipe Pereira, Marion Leleu, Zhou-Feng Chen, Claire Kelly, Matthias Merkenschlager, Amanda G Fisher
May 04, 2018
REST is a transcriptional repressor that targets a group of neuronal genes in non-neuronal cells. In embryonic stem (ES) cells, REST has been implicated in controlling the expression of transcription factor genes that are...
Bregman Itoh–Abe Methods for Sparse Optimisation
Abstract: In this paper we propose optimisation methods for variational regularisation problems based on discretising the inverse scale space flow with discrete gradient methods. Inverse scale space flow generalises gradient...
Optimising Exome Prenatal Sequencing Services (EXPRESS): a study protocol to evaluate rapid prenatal exome sequencing in the NHS Genomic Medicine Service [version 2; peer review
Melissa Hill, Sian Ellard, Jane Fisher, Naomi Fulop, Marian Knight, Mark Kroese, Jean Ledger, Kerry Leeson-Beevers, Alec McEwan, Dominic McMullan, Rhiannon Mellis, Stephen Morris, Michael Parker, Dagmar Tapon, Emma Baple, Laura Blackburn, Asya Choudry, Caroline Lafarge, Hannah McInnes-Dean, Michelle Peter, Rema Ramakrishnan, Lauren Roberts, Beverly Searle, Emma Smith, Holly Walton, Sarah L Wynn, Wing Han Wu, Lyn S Chitty
Sep 07, 2022
BACKGROUND: Prenatal exome sequencing (ES) for the diagnosis of fetal anomalies was implemented nationally in England in October 2020 by the NHS Genomic Medicine Service (GMS). The GMS is based around seven regional Genomic...
A recessive genetic screen for host factors required for retroviral infection in a library of insertionally mutated Blm-deficient embryonic stem cells.
BACKGROUND: Host factors required for retroviral infection are potential targets for the modulation of diseases caused by retroviruses. During the retroviral life cycle, numerous cellular factors interact with the virus and play...
|
|< |
< |
1 |