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Results: 30
Positive Energy Districts
Savis Gohari Krangsås, Koen Steemers, Thaleia Konstantinou, Silvia Soutullo, Mingming Liu, Emanuela Giancola, Bahri Prebreza, Touraj Ashrafian, Lina Murauskaitė, Nienke Maas
Sep 25, 2021
Positive Energy Districts (PED) are areas within cities that generate more renewable energy than they consume, contributing to cities’ energy system transformation toward carbon neutrality. Since PED is a novel concept, the...
Modelling osteomyelitis.
Pietro Liò, Nicola Paoletti, Mohammad Ali Moni, Kathryn Atwell, Emanuela Merelli, Marco Viceconti
Sep 07, 2012
Post-mortem computed tomography (PMCT) radiological findings and assessment in advanced decomposed bodies.
Gaia Cartocci, Alessandro Santurro, Margherita Neri, Fulvio Zaccagna, Carlo Catalano, Raffaele La Russa, Emanuela Turillazzi, Valeria Panebianco, Paola Frati, Vittorio Fineschi
Oct 17, 2019
PURPOSE: The aim of the study is to report radiological findings and features in advanced decomposed bodies obtained by post-mortem computed tomography (PMCT) with autopsy correlation. MATERIALS AND METHODS: This retrospective...
Efficacy and safety of the third-generation chloroethylnitrosourea fotemustine for the treatment of chemorefractory T-cell lymphomas.
Gaetano Corazzelli, Ferdinando Frigeri, Manuela Arcamone, Luigi Aloj, Gaetana Capobianco, Cristina Becchimanzi, Emanuela Morelli, Francesco Volzone, Gianpaolo Marcacci, Filippo Russo, Rosaria De Filippi, Secondo Lastoria, Antonio Pinto
Dec 21, 2018
Patients with recurring T-cell non-Hodgkin lymphoma (T-NHL) are incurable and candidate for investigational agents. Here, we report on five patients with T-NHL refractory to multiple chemotherapy lines, including in all cases...
A new PCR assay for the detection and differentiation of Babesia canis and Babesia vogeli.
Giada Annoscia, Maria Stefania Latrofa, Cinzia Cantacessi, Emanuela Olivieri, Maria Teresa Manfredi, Filipe Dantas-Torres, Domenico Otranto
Nov 28, 2017
Babesia spp. are globally distributed tick-borne protozoan parasites that infect the red blood cells of a wide range of vertebrate hosts, including humans. Diagnosis of babesiosis is often impeded by the transient presence of...
Circulating megakaryocyte and platelet microvesicles correlate with response to ruxolitinib and distinct disease severity in patients with myelofibrosis.
Martina Barone, Francesca Ricci, Daria Sollazzo, Emanuela Ottaviani, Marco Romano, Giuseppe Auteri, Daniela Bartoletti, Maria LB Reggiani, Nicola Vianelli, Pier L Tazzari, Michele Cavo, Dorian Forte, Francesca Palandri, Lucia Catani
May 06, 2019
G392E neuroserpin causing the dementia FENIB is secreted from cells but is not synaptotoxic.
Thies Ingwersen, Christian Linnenberg, Emanuela D'Acunto, Shabnam Temori, Irene Paolucci, David Wasilewski, Behnam Mohammadi, Johannes Kirchmair, Robert C Glen, Elena Miranda, Markus Glatzel, Giovanna Galliciotti
Apr 22, 2021
Recent Advancements and Applications of Human Immune System Mice in Preclinical Immuno-Oncology.
Michelle Curran, Maelle Mairesse, Alba Matas-Céspedes, Bethany Bareham, Giovanni Pellegrini, Ardi Liaunardy, Edward Powell, Rebecca Sargeant, Emanuela Cuomo, Richard Stebbings, Catherine J Betts, Kourosh Saeb-Parsy
Jan 20, 2020
Significant advances in immunotherapies have resulted in the increasing need of predictive preclinical models to improve immunotherapeutic drug development, treatment combination, and to prevent or minimize toxicity in clinical...
In vivo modeling of human neuron dynamics and Down syndrome.
Raquel Real, Manuel Peter, Antonio Trabalza, Shabana Khan, Mark A Smith, Joana Dopp, Samuel J Barnes, Ayiba Momoh, Alessio Strano, Emanuela Volpi, Graham Knott, Frederick J Livesey, Vincenzo De Paola
Nov 27, 2019
Ductal ligation timing and neonatal outcomes
Silvia Martini, Silvia Galletti, Wilf Kelsall, Emanuela Angeli, Marta Agulli, Gaetano Domenico Gargiulo, Si Emma Chen, Luigi Corvaglia, Yogen Singh
Jun 11, 2021
TTC19 Plays a Husbandry Role on UQCRFS1 Turnover in the Biogenesis of Mitochondrial Respiratory Complex III.
Emanuela Bottani, Raffaele Cerutti, Michael E Harbour, Sabrina Ravaglia, Sukru Anil Dogan, Carla Giordano, Ian M Fearnley, Giulia D'Amati, Carlo Viscomi, Erika Fernandez-Vizarra, Massimo Zeviani
Jun 27, 2018
Rieske protein TTC19 UQCRFS1 complex III deficiency mitochondrial complex III mitochondrial disease mitochondrial quality control mitochondrial respiratory chain mouse model Animals Behavior Animal Disease Models Animal Electron Transport Complex III Female Genotype HeLa Cells Humans Iron-Sulfur Proteins Kinetics Male Membrane Proteins Mice Inbred C57BL Mice Knockout Mitochondria Mitochondrial Diseases Mitochondrial Proteins Motor Activity Nerve Degeneration Nervous System Phenotype Protein Binding Protein Stability Proteolysis Reactive Oxygen Species
Platelets from patients with visceral obesity promote colon cancer growth.
Marica Cariello, Elena Piccinin, Emanuela Pasculli, Maria Arconzo, Roberta Zerlotin, Simona D'Amore, Francesca Mastropasqua, Claudia Peres, Giusi Graziano, Gaetano Villani, Graziano Pesole, Antonio Moschetta
Jul 08, 2022
Several studies highlighted the importance of platelets in the tumor microenvironment due to their ability to interact with other cell types such as leukocytes, endothelial, stromal and cancer cells. Platelets can influence...
Molecular and cognitive signatures of ageing partially restored through synthetic delivery of IL2 to the brain.
Neanderthals on the Lower Danube
Dušan Borić, Emanuela Cristiani, Rachel Hopkins, Jean‐Luc Schwenninger, Katarina Gerometta, Charly A. I. French, Giuseppina Mutri, Jelena Ćalić, Vesna Dimitrijević, Ana B. Marín‐Arroyo, Jennifer R. Jones, Rhiannon Stevens, Alana Masciana, Kevin Uno, Kristine Korzow Richter, Dragana Antonović, Karol Wehr, Christine Lane, Dustin White
Aug 26, 2021
SPECIAL ISSUE ARTICLE Special Issue Articles Cryptotephra Danube Gorges OSL dating Palaeolithic radiocarbon dating ZooMS
Published by: Journal of Quaternary Science
Blood-Based Biomarker Candidates of Cerebral Amyloid Using PiB PET in Non-Demented Elderly.
Sarah Westwood, Emanuela Leoni, Abdul Hye, Steven Lynham, Mizanur R Khondoker, Nicholas J Ashton, Steven J Kiddle, Alison L Baird, Ricardo Sainz-Fuertes, Rufina Leung, John Graf, Cristina Tan Hehir, David Baker, Cristina Cereda, Chantal Bazenet, Malcolm Ward, Madhav Thambisetty, Simon Lovestone
Jun 11, 2018
Increasingly, clinical trials for Alzheimer's disease (AD) are being conducted earlier in the disease phase and with biomarker confirmation using in vivo amyloid PET imaging or CSF tau and Aβ measures to quantify pathology....
KeywordsAlzheimer’s disease Amyloid biological markers Blood Plasma Preclinical Proteomics Aged Alzheimer Disease Amyloidogenic Proteins Aniline Compounds Benzothiazoles Biomarkers Brain Brain Chemistry Female Humans Male Positron-Emission Tomography Tandem Mass Spectrometry Thiazoles alpha-Macroglobulins
Effects of Germline VHL Deficiency on Growth, Metabolism, and Mitochondria.
Silverio Perrotta, Domenico Roberti, Debora Bencivenga, Paola Corsetto, Katie A O'Brien, Martina Caiazza, Emanuela Stampone, Leanne Allison, Roland A Fleck, Saverio Scianguetta, Immacolata Tartaglione, Peter A Robbins, Maddalena Casale, James A West, Clara Franzini-Armstrong, Julian L Griffin, Angela M Rizzo, Antonio A Sinisi, Andrew J Murray, Adriana Borriello, Federico Formenti, Fulvio Della Ragione
Mar 03, 2020
Mutations in VHL, which encodes von Hippel-Lindau tumor suppressor (VHL), are associated with divergent diseases. We describe a patient with marked erythrocytosis and prominent mitochondrial alterations associated with a severe...
Novel and Rare Fusion Transcripts Involving Transcription Factors and Tumor Suppressor Genes in Acute Myeloid Leukemia.
Antonella Padella, Giorgia Simonetti, Giulia Paciello, George Giotopoulos, Carmen Baldazzi, Simona Righi, Martina Ghetti, Anna Stengel, Viviana Guadagnuolo, Rossella De Tommaso, Cristina Papayannidis, Valentina Robustelli, Eugenia Franchini, Andrea Ghelli Luserna di Rorà, Anna Ferrari, Maria Chiara Fontana, Samantha Bruno, Emanuela Ottaviani, Simona Soverini, Clelia Tiziana Storlazzi, Claudia Haferlach, Elena Sabattini, Nicoletta Testoni, Ilaria Iacobucci, Brian JP Huntly, Elisa Ficarra, Giovanni Martinelli
Dec 19, 2019
Approximately 18% of acute myeloid leukemia (AML) cases express a fusion transcript. However, few fusions are recurrent across AML and the identification of these rare chimeras is of interest to characterize AML patients. Here...
Next-generation sequencing for the diagnosis of MYH9-RD
Loredana Bury, Karyn Megy, Jonathan C Stephens, Luigi Grassi, Daniel Greene, Nick Gleadall, Karina Althaus, David Allsup, Tadbir K Bariana, Mariana Bonduel, Nora V Butta, Peter Collins, Nicola Curry, Sri VV Deevi, Kate Downes, Daniel Duarte, Kim Elliott, Emanuela Falcinelli, Bruce Furie, David Keeling, Michele P Lambert, Rachel Linger, Sarah Mangles, Rutendo Mapeta, Carolyn M Millar, Christopher Penkett, David J Perry, Kathleen E Stirrups, Ernest Turro, Sarah K Westbury, John Wu, Nihr BioResource, Keith Gomez, Kathleen Freson, Willem H Ouwehand, Paolo Gresele, Ilenia Simeoni
Nov 15, 2019
SARS-CoV-2 lineage B.1.1.7 is associated with greater disease severity among hospitalised women but not men
Oliver Stirrup, Florencia Boshier, Cristina Venturini, José Afonso Guerra-Assunção, Adela Alcolea-Medina, Angela Beckett, Themoula Charalampous, Ana da Silva Filipe, Sharon Glaysher, Tabassum Khan, Raghavendran Kulasegaran Shylini, Beatrix Kele, Irene Monahan, Guy Mollett, Matthew Parker, Emanuela Pelosi, Paul Randell, Sunando Roy, Joshua Taylor, Sophie Weller, Eleri Wilson-Davies, Phillip Wade, Rachel Williams, COG-UK-HOCI Variant substudy consortium, COVID-19 Genomics UK (COG-UK) Consortium, Andrew Copas, Maria-Teresa Cutino-Moguel, Nick Freemantle, Andrew C Hayward, Alison Holmes, Joseph Hughes, Tabitha Mahungu, Gaia Nebbia, David Partridge, Cassie Pope, James Price, Samuel Robson, Kordo Saeed, Thushan de Silva, Luke Snell, Emma Thomson, Adam A Witney, Judith Breuer
Oct 21, 2021
Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation.
Lidia Yshii, Emanuela Pasciuto, Pascal Bielefeld, Loriana Mascali, Pierre Lemaitre, Marika Marino, James Dooley, Lubna Kouser, Stijn Verschoren, Vasiliki Lagou, Hannelore Kemps, Pascal Gervois, Antina de Boer, Oliver T Burton, Jérôme Wahis, Jens Verhaert, Samar Hk Tareen, Carlos P Roca, Kailash Singh, Carly E Whyte, Axelle Kerstens, Zsuzsanna Callaerts-Vegh, Suresh Poovathingal, Teresa Prezzemolo, Keimpe Wierda, Amy Dashwood, Junhua Xie, Elien Van Wonterghem, Eline Creemers, Meryem Aloulou, Willy Gsell, Oihane Abiega, Sebastian Munck, Roosmarijn E Vandenbroucke, Annelies Bronckaers, Robin Lemmens, Bart De Strooper, Ludo Van Den Bosch, Uwe Himmelreich, Carlos P Fitzsimons, Matthew G Holt, Adrian Liston
Jun 08, 2022
The ability of immune-modulating biologics to prevent and reverse pathology has transformed recent clinical practice. Full utility in the neuroinflammation space, however, requires identification of both effective targets for...
Social cognition impairment in genetic frontotemporal dementia within the GENFI cohort.
Lucy L Russell, Caroline V Greaves, Martina Bocchetta, Jennifer Nicholas, Rhian S Convery, Katrina Moore, David M Cash, John van Swieten, Lize Jiskoot, Fermin Moreno, Raquel Sanchez-Valle, Barbara Borroni, Robert Laforce, Mario Masellis, Maria Carmela Tartaglia, Caroline Graff, Emanuela Rotondo, Daniela Galimberti, James B Rowe, Elizabeth Finger, Matthis Synofzik, Rik Vandenberghe, Alexandre de Mendonça, Fabrizio Tagliavini, Isabel Santana, Simon Ducharme, Chris Butler, Alex Gerhard, Johannes Levin, Adrian Danek, Markus Otto, Jason D Warren, Jonathan D Rohrer, GENFI Genetic FTD Initiative
Jan 22, 2021
A key symptom of frontotemporal dementia (FTD) is difficulty interacting socially with others. Social cognition problems in FTD include impaired emotion processing and theory of mind difficulties, and whilst these have been...
Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation.
Lidia Yshii, Emanuela Pasciuto, Pascal Bielefeld, Loriana Mascali, Pierre Lemaitre, Marika Marino, James Dooley, Lubna Kouser, Stijn Verschoren, Vasiliki Lagou, Hannelore Kemps, Pascal Gervois, Antina de Boer, Oliver T Burton, Jérôme Wahis, Jens Verhaert, Samar Hk Tareen, Carlos P Roca, Kailash Singh, Carly E Whyte, Axelle Kerstens, Zsuzsanna Callaerts-Vegh, Suresh Poovathingal, Teresa Prezzemolo, Keimpe Wierda, Amy Dashwood, Junhua Xie, Elien Van Wonterghem, Eline Creemers, Meryem Aloulou, Willy Gsell, Oihane Abiega, Sebastian Munck, Roosmarijn E Vandenbroucke, Annelies Bronckaers, Robin Lemmens, Bart De Strooper, Ludo Van Den Bosch, Uwe Himmelreich, Carlos P Fitzsimons, Matthew G Holt, Adrian Liston
Jun 29, 2022
The ability of immune-modulating biologics to prevent and reverse pathology has transformed recent clinical practice. Full utility in the neuroinflammation space, however, requires identification of both effective targets for...
The Alpha variant was not associated with excess nosocomial SARS-CoV-2 infection in a multi-centre UK hospital study.
Florencia AT Boshier, Cristina Venturini, Oliver Stirrup, José Afonso Guerra-Assunção, Adela Alcolea-Medina, Angela H Becket, Matthew Byott, Themoula Charalampous, Ana Da Silva Filipe, Dan Frampton, Sharon Glaysher, Tabassum Khan, Raghavendran Kulasegara-Shylini, Beatrix Kele, Irene M Monahan, Guy Mollett, Matthew Parker, Emanuela Pelosi, Paul Randell, Sunando Roy, Joshua F Taylor, Sophie J Weller, Eleri Wilson-Davies, Phillip Wade, Rachel Williams, Andrew J Copas, Teresa Cutino-Moguel, Nick Freemantle, Andrew C Hayward, Alison Holmes, Joseph Hughes, Tabitha W Mahungu, Gaia Nebbia, Eleni Nastouli, David G Partridge, Cassie F Pope, James R Price, Samuel C Robson, Kordo Saeed, Gee Yen Shin, Thushan I de Silva, Luke B Snell, Emma C Thomson, Adam A Witney, Judith Breuer, The COVID-19 Genomics UK (COG-UK) consortium COG-UK HOCI Variant Substudy consortium*
Nov 01, 2021
The BioMart community portal
Damian Smedley, Syed Haider, Steffen Durinck, Luca Pandini, Paolo Provero, James Allen, Olivier Arnaiz, Mohammad Hamza Awedh, Richard Baldock, Giulia Barbiera, Philippe Bardou, Tim Beck, Andrew Blake, Merideth Bonierbale, Anthony J Brookes, Gabriele Bucci, Iwan Buetti, Sarah Burge, Cédric Cabau, Joseph W Carlson, Claude Chelala, Charalambos Chrysostomou, Davide Cittaro, Olivier Collin, Raul Cordova, Rosalind J Cutts, Erik Dassi, Alex Di Genova, Anis Djari, Anthony Esposito, Heather Estrella, Eduardo Eyras, Julio Fernandez-Banet, Simon Forbes, Robert C Free, Takatomo Fujisawa, Emanuela Gadaleta, Jose M Garcia-Manteiga, David Goodstein, Kristian Gray, José Afonso Guerra-Assunção, Bernard Haggarty, Dong-Jin Han, Byung Woo Han, Todd Harris, Jayson Harshbarger, Robert K Hastings, Richard D Hayes, Claire Hoede, Shen Hu, Zhi-Liang Hu, Lucie Hutchins, Zhengyan Kan, Hideya Kawaji, Aminah Keliet, Arnaud Kerhornou, Sunghoon Kim, Rhoda Kinsella, Christophe Klopp, Lei Kong, Daniel Lawson, Dejan Lazarevic, Ji-Hyun Lee, Thomas Letellier, Chuan-Yun Li, Pietro Lio, Chu-Jun Liu, Jie Luo, Alejandro Maass, Jerome Mariette, Thomas Maurel, Stefania Merella, Azza Mostafa Mohamed, Francois Moreews, Ibounyamine Nabihoudine, Nelson Ndegwa, Céline Noirot, Cristian Perez-Llamas, Michael Primig, Alessandro Quattrone, Hadi Quesneville, Davide Rambaldi, James Reecy, Michela Riba, Steven Rosanoff, Amna Ali Saddiq, Elisa Salas, Olivier Sallou, Rebecca Shepherd, Reinhard Simon, Linda Sperling, William Spooner, Daniel M Staines, Delphine Steinbach, Kevin Stone, Elia Stupka, Jon W Teague, Abu Z Dayem Ullah, Jun Wang, Doreen Ware, Marie Wong-Erasmus, Ken Youens-Clark, Amonida Zadissa, Shi-Jian Zhang, Arek Kasprzyk
Sep 18, 2020
The BioMart Community Portal (www.biomart.org) is a community-driven effort to provide a unified interface to biomedical databases that are distributed worldwide. The portal provides access to numerous database projects...
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