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John Panteleimon Manoussakis, ed. After God: Richard Kearney and the Religious Turn in Continental Philosophy. New York
Eric Severson
May 04, 2009
[Book Review] Eric Severson reviews John Panteleimon Manoussakis, ed. After God: Richard Kearney and the Religious Turn in Continental Philosophy. New York: Fordham University Press, 2005.
Published by: Memorial University of Newfoundland
B-hadron production in NNLO QCD
We calculate, for the first time, the NNLO QCD corrections to identified
heavy hadron production at hadron colliders. The calculation is based on a
flexible numeric framework which allows the calculation of any distribution of
a...
John Panteleimon Manoussakis, ed. After God: Richard Kearney and the Religious Turn in Continental Philosophy. New York
Eric Severson
May 04, 2009
[Book Review] Eric Severson reviews John Panteleimon Manoussakis, ed. After God: Richard Kearney and the Religious Turn in Continental Philosophy. New York: Fordham University Press, 2005.
Published by: Memorial University of Newfoundland
Peter Gratton and John Panteleimon Manoussakis, eds. Traversing the Imaginary: Richard Kearney and the Postmodern Challenge. Evanston, Ill.
Eric Severson
May 04, 2009
Book Review. Eric Severson reviews Peter Gratton and John Panteleimon Manoussakis, eds. Traversing the Imaginary: Richard Kearney and the Postmodern Challenge. Evanston, Ill.: Northwestern University Press, 2007.
Published by: Memorial University of Newfoundland
Peter Gratton and John Panteleimon Manoussakis, eds. Traversing the Imaginary: Richard Kearney and the Postmodern Challenge. Evanston, Ill.
Eric Severson
May 04, 2009
Book Review. Eric Severson reviews Peter Gratton and John Panteleimon Manoussakis, eds. Traversing the Imaginary: Richard Kearney and the Postmodern Challenge. Evanston, Ill.: Northwestern University Press, 2007.
Published by: Memorial University of Newfoundland
Restriction endonuclease TseI cleaves A:A and T
Long Ma, Kai Chen, David J Clarke, Christopher P Nortcliffe, Geoffrey G Wilson, J Michael Edwardson, A Jennifer Morton, Anita C Jones, David TF Dryden
Feb 13, 2020
The type II restriction endonuclease TseI recognizes the DNA target sequence 5'-G^CWGC-3' (where W = A or T) and cleaves after the first G to produce fragments with three-base 5'-overhangs. We have determined that it is a...
ERIC-PCR Analysis of the Clinical and Environmental strains of V. cholerae during 2013 Epidemic in Nigeria
Smith Stella, Nwaokorie Francisca, Awoderu Oluwatoyin, Bamidele Tajudeen, Akinsinde Kehinde, Ochoga Michael, Oladele David, Bamidele Moses, Fesobi Toun, Afocha Eberechukwu, Amoo Samuel, Ajayi Morakinyo, Atat Prince, Ogbonna Francisca, Nduaga Samuel, Idika Nneoma, Oparaugo Chinedu, Musa Adesola, Adeneye Adeniyi, Ijeh Margaret, Ujah Innocent
Nov 21, 2015
Background: Molecular markers are important tools in the monitoring of toxigenic strains of Vibrio cholerae in environmental and clinical samples.
Objectives: The study was aimed at determining the clinical and environmental...
Published by: IJHS Medical Association
ERIC-PCR Analysis of the Clinical and Environmental strains of V. cholerae during 2013 Epidemic in Nigeria
Smith Stella, Nwaokorie Francisca, Awoderu Oluwatoyin, Bamidele Tajudeen, Akinsinde Kehinde, Ochoga Michael, Oladele David, Bamidele Moses, Fesobi Toun, Afocha Eberechukwu, Amoo Samuel, Ajayi Morakinyo, Atat Prince, Ogbonna Francisca, Nduaga Samuel, Idika Nneoma, Oparaugo Chinedu, Musa Adesola, Adeneye Adeniyi, Ijeh Margaret, Ujah Innocent
Nov 21, 2015
Background: Molecular markers are important tools in the monitoring of toxigenic strains of Vibrio cholerae in environmental and clinical samples.
Objectives: The study was aimed at determining the clinical and environmental...
Published by: IJHS Medical Association
Interview with Booker T. Brown - OH 689
This interview was conducted by Dr. George Garrison with Booker T. Brown with a focus on the History of Emmett Scott High School. Emmett Scott was the segregated high school for African-Americans, which was named after Emmett...
Published by: Winthrop University
Serine Is an Essential Metabolite for Effector T Cell Expansion.
Eric H Ma, Glenn Bantug, Takla Griss, Stephanie Condotta, Radia M Johnson, Bozena Samborska, Nello Mainolfi, Vipin Suri, Hannah Guak, Maria L Balmer, Mark J Verway, Thomas C Raissi, Harmony Tsui, Giselle Boukhaled, Sofia Henriques da Costa, Christian Frezza, Connie M Krawczyk, Adam Friedman, Mark Manfredi, Martin J Richer, Christoph Hess, Russell G Jones
Jan 12, 2018
During immune challenge, T lymphocytes engage pathways of anabolic metabolism to support clonal expansion and the development of effector functions. Here we report a critical role for the non-essential amino acid serine in...
Phgdh Shmt T cell Glycolysis immunometabolism Immunotherapy Metabolic reprogramming metabolism Serine serine biosynthesis Animals Carbon Cell Cycle Checkpoints Cell Proliferation Diet Energy Metabolism Extracellular Space Glycine Listeria monocytogenes Metabolic Networks and Pathways Metabolome Mice Inbred C57BL Purine Nucleotides Serine T-Lymphocytes
PI3Kδ Forms Distinct Multiprotein Complexes at the TCR Signalosome in Naïve and Differentiated CD4 + T Cells
Daisy H. Luff, Katarzyna Wojdyla, David Oxley, Tamara Chessa, Kevin Hudson, Phillip T. Hawkins, Len R. Stephens, Simon T. Barry, Klaus Okkenhaug
Mar 22, 2021
Phosphoinositide 3-kinases (PI3Ks) play a central role in adaptive immunity by transducing signals from the T cell antigen receptor (TCR) via production of PIP3. PI3Kδ is a heterodimer composed of a p110δ catalytic subunit...
PI3Kδ Forms Distinct Multiprotein Complexes at the TCR Signalosome in Naïve and Differentiated CD4+ T Cells.
Daisy H Luff, Katarzyna Wojdyla, David Oxley, Tamara Chessa, Kevin Hudson, Phillip T Hawkins, Len R Stephens, Simon T Barry, Klaus Okkenhaug
Feb 03, 2021
Phosphoinositide 3-kinases (PI3Ks) play a central role in adaptive immunity by transducing signals from the T cell antigen receptor (TCR) via production of PIP3. PI3Kδ is a heterodimer composed of a p110δ catalytic subunit...
CD4-Positive T-Lymphocytes Animals Mice Inbred C57BL Mice Multiprotein Complexes Receptors Antigen T-Cell Interleukin-2 Lymphocyte Activation Specific Pathogen-Free Organisms Signal Transduction Cell Differentiation Gene Knockout Techniques Class I Phosphatidylinositol 3-Kinases CRISPR-Cas Systems Gene Editing
Serine Is an Essential Metabolite for Effector T Cell Expansion.
Eric H Ma, Glenn Bantug, Takla Griss, Stephanie Condotta, Radia M Johnson, Bozena Samborska, Nello Mainolfi, Vipin Suri, Hannah Guak, Maria L Balmer, Mark J Verway, Thomas C Raissi, Harmony Tsui, Giselle Boukhaled, Sofia Henriques da Costa, Christian Frezza, Connie M Krawczyk, Adam Friedman, Mark Manfredi, Martin J Richer, Christoph Hess, Russell G Jones
Sep 05, 2018
During immune challenge, T lymphocytes engage pathways of anabolic metabolism to meet the demands of clonal expansion and development of effector functions. Here we report a critical role for the non-essential amino acid serine...
Extracellular Lactate
James T Grist, Lorna B Jarvis, Zoya Georgieva, Sara Thompson, Harpreet Kaur Sandhu, Keith Burling, Ashley Clarke, Sarah Jackson, Mark Wills, Ferdia A Gallagher, Joanne L Jones
Feb 23, 2018
Following activation, T cells rapidly divide and acquire effector functions. This energetically demanding process depends upon the ability of T cells to undergo metabolic remodeling from oxidative phosphorylation to aerobic...
T Lymphocytes in Histiocytic Sarcomas of Flat-Coated Retriever Dogs.
Flat-Coated Retriever dogs are predisposed to the development of histiocytic sarcoma (HS), a poorly differentiated, highly malignant neoplasm. The authors have previously documented a significant lymphocytic infiltrate in such...
The microRNA miR-155 controls CD8(+) T cell responses by regulating interferon signaling.
Donald T Gracias, Erietta Stelekati, Jennifer L Hope, Alina C Boesteanu, Travis A Doering, Jillian Norton, Yvonne M Mueller, Joseph A Fraietta, E John Wherry, Martin Turner, Peter D Katsikis
Aug 14, 2019
We found upregulation of expression of the microRNA miR-155 in primary effector and effector memory CD8(+) T cells, but low miR-155 expression in naive and central memory cells. Antiviral CD8(+) T cell responses and viral...
Animals CD8-Positive T-Lymphocytes Cell Proliferation Flow Cytometry Gene Expression Profiling Gene Regulatory Networks Immunoblotting Immunologic Memory Interferon Regulatory Factor-7 Interferons Mice Mice Inbred C57BL Mice Knockout MicroRNAs Oligonucleotide Array Sequence Analysis Orthomyxoviridae Orthomyxoviridae Infections RNA Interference Reverse Transcriptase Polymerase Chain Reaction STAT1 Transcription Factor Signal Transduction Suppressor of Cytokine Signaling 1 Protein Suppressor of Cytokine Signaling Proteins
High fidelity analysis to predict failure in T-joints
Composite T-joints and similar skin-stiffener joints have a central role in aerospace structures. However, their accurate numerical analysis is still a great challenge due to their complex geometry and stress state during...
High fidelity analysis to predict failure in T-joints
Composite T-joints and similar skin-stiffener joints have a central role in aerospace structures. However, their accurate numerical analysis is still a great challenge due to their complex geometry and stress state during...
CD97 stabilises the immunological synapse between dendritic cells and T cells and is targeted for degradation by the Salmonella effector SteD
Ondrej Cerny, Camilla Godlee, Romina Tocci, Nancy E. Cross, Haoran Shi, James C. Williamson, Eric Alix, Paul J. Lehner, David W. Holden
Aug 11, 2021
The Salmonella enterica effector SteD depletes mature MHC class II (mMHCII) molecules from the surface of infected antigen-presenting cells through ubiquitination of the cytoplasmic tail of the mMHCII β chain. This requires the...
An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression.
Asis Palazon, Petros A Tyrakis, David Macias, Pedro Veliça, Helene Rundqvist, Susan Fitzpatrick, Nikola Vojnovic, Anthony T Phan, Niklas Loman, Ingrid Hedenfalk, Thomas Hatschek, John Lövrot, Theodoros Foukakis, Ananda W Goldrath, Jonas Bergh, Randall S Johnson
May 31, 2018
Cytotoxic T cells infiltrating tumors are thought to utilize HIF transcription factors during adaptation to the hypoxic tumor microenvironment. Deletion analyses of the two key HIF isoforms found that HIF-1α, but not HIF-2α, was...
HIF transcription factors VEGF angiogenesis cytotoxic T cells Hypoxia Immunotherapy Animals Breast Neoplasms CD8-Positive T-Lymphocytes Cell Line Tumor Cells Cultured Disease Progression Female Gene Expression Profiling Gene Expression Regulation Neoplastic Humans Hypoxia-Inducible Factor 1 alpha Subunit Mice Inbred C57BL Mice Knockout Neoplasms Experimental Neovascularization Pathologic T-Lymphocytes Cytotoxic Vascular Endothelial Growth Factor A
Carcinomas assemble a filamentous CXCL12-keratin-19 coating that suppresses T cell-mediated immune attack.
Zhikai Wang, Philip Moresco, Ran Yan, Jiayun Li, Ya Gao, Daniele Biasci, Min Yao, Jordan Pearson, Jaclyn F Hechtman, Tobias Janowitz, Raza M Zaidi, Matthew J Weiss, Douglas T Fearon
Feb 20, 2022
Cancer immunotherapy frequently fails because most carcinomas have few T cells, suggesting that cancers can suppress T cell infiltration. Here, we show that cancer cells of human pancreatic ductal adenocarcinoma (PDA)...
Review of Eric L. Jenkins, Free to Say No? Free Will and Augustine’s Evolving Doctrines of Grace and Election (Cambridge
Seamus O'Neill
Mar 23, 2016
Eric Jenkins’ Free to Say No? Free Will and Augustine’s Evolving Doctrines of Grace and Election is a relatively concise and highly readable investigation into Augustine’s changing position on the freedom of the will and various...
Published by: Memorial University of Newfoundland
CD97 stabilises the immunological synapse between dendritic cells and T cells and is targeted for degradation by the Salmonella effector SteD.
Ondrej Cerny, Camilla Godlee, Romina Tocci, Nancy E Cross, Haoran Shi, James C Williamson, Eric Alix, Paul J Lehner, David W Holden
Aug 27, 2021
The Salmonella enterica effector SteD depletes mature MHC class II (mMHCII) molecules from the surface of infected antigen-presenting cells through ubiquitination of the cytoplasmic tail of the mMHCII β chain. This requires the...
Does the PI3K pathway promote or antagonize regulatory T cell development and function?
Regulatory T cells (Tregs) prevent autoimmunity and inflammation by suppressing the activation of other T cells and antigen presenting cells. The role of phosphoinositide 3-kinase (PI3K) signaling in Treg is controversial. Some...
Cardiac Arrhythmia, CHF, and NSR Classification With NCA-Based Feature Fusion and SVM Classifier
An arrhythmia is an irregular heartbeat that causes abnormal heart rhythms. Manual analysis of electrocardiogram (ECG) signals is not sufficient to quickly detect cardiac arrhythmias. This study proposes a deep learning approach...
Systems & Software Design Computer Science and Information Technology Systems and Software Engineering
Published by: IGI Global Scientific Publishing
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