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Results: 9477
Layman Craig, 1949
The Rockefeller University
Jan 01, 0001
Lyman C. Craig. Isolation and characterization of biologically important substances
Lecture delivered December 15, 1949
Posted with permission
Published by: Charles C. Thomas Publisher
The Application of Functional Metagenomics to Natural Products Research
Jeffrey William Craig
Jan 01, 0001
The study of bacterial natural products offers important insights into the physiologies and behaviors of individual species of bacteria as well as the contributions of these organisms to complex microbial communities. Such...
Published by: Rockefeller University
T lymphocyte senescence is attenuated in Parkinson’s disease
Antonina Kouli, Melanie Jensen, Vanesa Papastavrou, Kirsten M. Scott, Claire Kolenda, Craig Parker, Imtiaz H. Solim, Marta Camacho, Carmen Martin-Ruiz, Caroline H. Williams-Gray
Oct 13, 2021
Abstract: Background: Immune involvement is well-described in Parkinson’s disease (PD), including an adaptive T lymphocyte response. Given the increasing prevalence of Parkinson’s disease in older age, age-related dysregulation...
B-hadron production in NNLO QCD
We calculate, for the first time, the NNLO QCD corrections to identified
heavy hadron production at hadron colliders. The calculation is based on a
flexible numeric framework which allows the calculation of any distribution of
a...
T lymphocyte senescence is attenuated in Parkinson's disease.
Antonina Kouli, Melanie Jensen, Vanesa Papastavrou, Kirsten M Scott, Claire Kolenda, Craig Parker, Imtiaz H Solim, Marta Camacho, Carmen Martin-Ruiz, Caroline H Williams-Gray
Nov 22, 2021
Background
Immune involvement is well-described in Parkinson's disease (PD), including an adaptive T lymphocyte response. Given the increasing prevalence of Parkinson's disease in older age, age-related dysregulation of...
Published by: Journal of neuroinflammation
T lymphocyte senescence is attenuated in Parkinson's disease.
Antonina Kouli, Melanie Jensen, Vanesa Papastavrou, Kirsten M Scott, Claire Kolenda, Craig Parker, Imtiaz H Solim, Marta Camacho, Carmen Martin-Ruiz, Caroline H Williams-Gray
Oct 07, 2021
BACKGROUND: Immune involvement is well-described in Parkinson's disease (PD), including an adaptive T lymphocyte response. Given the increasing prevalence of Parkinson's disease in older age, age-related dysregulation of T...
Restriction endonuclease TseI cleaves A:A and T
Long Ma, Kai Chen, David J Clarke, Christopher P Nortcliffe, Geoffrey G Wilson, J Michael Edwardson, A Jennifer Morton, Anita C Jones, David TF Dryden
Feb 13, 2020
The type II restriction endonuclease TseI recognizes the DNA target sequence 5'-G^CWGC-3' (where W = A or T) and cleaves after the first G to produce fragments with three-base 5'-overhangs. We have determined that it is a...
Receptor- G Protein Interactions in the Visual System: A Study of Structures and Mechanisms That Couple the Cytoplasmic Surface of Rhodopsin to the Nucleotide-Binding Pocket of Transducin
Ethan P Marin
Jan 01, 0001
The intermolecular interaction between the photoreceptor rhodopsin and the heterotrimeric G protein transducin (Gt) initiates the vertebrate phototransduction cascade. This interaction also serves as a model system for the study...
Published by: Rockefeller University
Interview with Booker T. Brown - OH 689
This interview was conducted by Dr. George Garrison with Booker T. Brown with a focus on the History of Emmett Scott High School. Emmett Scott was the segregated high school for African-Americans, which was named after Emmett...
Published by: Winthrop University
PI3Kδ Forms Distinct Multiprotein Complexes at the TCR Signalosome in Naïve and Differentiated CD4 + T Cells
Daisy H. Luff, Katarzyna Wojdyla, David Oxley, Tamara Chessa, Kevin Hudson, Phillip T. Hawkins, Len R. Stephens, Simon T. Barry, Klaus Okkenhaug
Mar 22, 2021
Phosphoinositide 3-kinases (PI3Ks) play a central role in adaptive immunity by transducing signals from the T cell antigen receptor (TCR) via production of PIP3. PI3Kδ is a heterodimer composed of a p110δ catalytic subunit...
PI3Kδ Forms Distinct Multiprotein Complexes at the TCR Signalosome in Naïve and Differentiated CD4+ T Cells.
Daisy H Luff, Katarzyna Wojdyla, David Oxley, Tamara Chessa, Kevin Hudson, Phillip T Hawkins, Len R Stephens, Simon T Barry, Klaus Okkenhaug
Feb 03, 2021
Phosphoinositide 3-kinases (PI3Ks) play a central role in adaptive immunity by transducing signals from the T cell antigen receptor (TCR) via production of PIP3. PI3Kδ is a heterodimer composed of a p110δ catalytic subunit...
CD4-Positive T-Lymphocytes Animals Mice Inbred C57BL Mice Multiprotein Complexes Receptors Antigen T-Cell Interleukin-2 Lymphocyte Activation Specific Pathogen-Free Organisms Signal Transduction Cell Differentiation Gene Knockout Techniques Class I Phosphatidylinositol 3-Kinases CRISPR-Cas Systems Gene Editing
Extracellular Lactate
James T Grist, Lorna B Jarvis, Zoya Georgieva, Sara Thompson, Harpreet Kaur Sandhu, Keith Burling, Ashley Clarke, Sarah Jackson, Mark Wills, Ferdia A Gallagher, Joanne L Jones
Feb 23, 2018
Following activation, T cells rapidly divide and acquire effector functions. This energetically demanding process depends upon the ability of T cells to undergo metabolic remodeling from oxidative phosphorylation to aerobic...
T Lymphocytes in Histiocytic Sarcomas of Flat-Coated Retriever Dogs.
Flat-Coated Retriever dogs are predisposed to the development of histiocytic sarcoma (HS), a poorly differentiated, highly malignant neoplasm. The authors have previously documented a significant lymphocytic infiltrate in such...
Correction to: The Edinburgh Consensus
Craig W Ritchie, Tom C Russ, Sube Banerjee, Bob Barber, Andrew Boaden, Nick C Fox, Clive Holmes, Jeremy D Isaacs, Ira Leroi, Simon Lovestone, Matt Norton, John O'Brien, Jim Pearson, Richard Perry, James Pickett, Adam D Waldman, Wai Lup Wong, Martin N Rossor, Alistair Burns
Jul 31, 2018
Since the publication of this article [1], it has come to the attention of the authors that information for one of the authors was not included in the competing interests section. Craig Richie has declared potential competing...
Endorsement of the 66/68 joint count for the measurement of musculoskeletal disease activity
Alí Duarte-García, Ying Ying Leung, Laura C Coates, Dorcas Beaton, Robin Christensen, Ethan T Craig, Maarten de Wit, Lihi Eder, Lara Fallon, Oliver FitzGerald, Dafna D Gladman, Niti Goel, Richard Holland, Chris Lindsay, Lara Maxwell, Philip Mease, Ana Maria Orbai, Bev Shea, Vibeke Strand, Douglas J Veale, William Tillett, Alexis Ogdie
Aug 01, 2019
Objective. The Psoriatic Arthritis (PsA) Core Domain Set for randomized controlled trials and longitudinal observational studies has recently been updated. The joint counts are central to the measurement of the peripheral...
The Ursinus Weekly, March 22, 1965
Craig S. Hill, Patricia Rodimer, Robert S. Laughlin, Mary Anne Holmgren, Marianne Murphy, Samuel Walker, Karen Kohn, Dorothy Davis, Anne Harris
Jan 01, 0001
Dr. Eugene Miller campaigns for local democratic mayoralty Curtain Club announces cast of Spring play Frank Sheeder named new editor-in-chief of Weekly: Editorial staff to be announced in April "Ruby" sales to end on Friday ...
Ursinus College Collegeville Pennsylvania newspaper Eugene H. Miller Ruby Beardwood Chemical Society radio station Curtain Club Frank Sheeder Alumni Association Julius Seelye Bixler Paisley Hall student government fraternities sororities humor satire Hobson Hall Ursinus Weakly April Fool's Day cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
The microRNA miR-155 controls CD8(+) T cell responses by regulating interferon signaling.
Donald T Gracias, Erietta Stelekati, Jennifer L Hope, Alina C Boesteanu, Travis A Doering, Jillian Norton, Yvonne M Mueller, Joseph A Fraietta, E John Wherry, Martin Turner, Peter D Katsikis
Aug 14, 2019
We found upregulation of expression of the microRNA miR-155 in primary effector and effector memory CD8(+) T cells, but low miR-155 expression in naive and central memory cells. Antiviral CD8(+) T cell responses and viral...
Animals CD8-Positive T-Lymphocytes Cell Proliferation Flow Cytometry Gene Expression Profiling Gene Regulatory Networks Immunoblotting Immunologic Memory Interferon Regulatory Factor-7 Interferons Mice Mice Inbred C57BL Mice Knockout MicroRNAs Oligonucleotide Array Sequence Analysis Orthomyxoviridae Orthomyxoviridae Infections RNA Interference Reverse Transcriptase Polymerase Chain Reaction STAT1 Transcription Factor Signal Transduction Suppressor of Cytokine Signaling 1 Protein Suppressor of Cytokine Signaling Proteins
Endorsement of the 66/68 joint count for the measurement of musculoskeletal disease activity
Alí Duarte-García, Ying Ying Leung, Laura C Coates, Dorcas Beaton, Robin Christensen, Ethan T Craig, Maarten de Wit, Lihi Eder, Lara Fallon, Oliver FitzGerald, Dafna D Gladman, Niti Goel, Richard Holland, Chris Lindsay, Lara Maxwell, Philip Mease, Ana Maria Orbai, Bev Shea, Vibeke Strand, Douglas J Veale, William Tillett, Alexis Ogdie
Aug 01, 2019
Objective. The Psoriatic Arthritis (PsA) Core Domain Set for randomized controlled trials and longitudinal observational studies has recently been updated. The joint counts are central to the measurement of the peripheral...
High fidelity analysis to predict failure in T-joints
Composite T-joints and similar skin-stiffener joints have a central role in aerospace structures. However, their accurate numerical analysis is still a great challenge due to their complex geometry and stress state during...
High fidelity analysis to predict failure in T-joints
Composite T-joints and similar skin-stiffener joints have a central role in aerospace structures. However, their accurate numerical analysis is still a great challenge due to their complex geometry and stress state during...
An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression.
Asis Palazon, Petros A Tyrakis, David Macias, Pedro Veliça, Helene Rundqvist, Susan Fitzpatrick, Nikola Vojnovic, Anthony T Phan, Niklas Loman, Ingrid Hedenfalk, Thomas Hatschek, John Lövrot, Theodoros Foukakis, Ananda W Goldrath, Jonas Bergh, Randall S Johnson
May 31, 2018
Cytotoxic T cells infiltrating tumors are thought to utilize HIF transcription factors during adaptation to the hypoxic tumor microenvironment. Deletion analyses of the two key HIF isoforms found that HIF-1α, but not HIF-2α, was...
HIF transcription factors VEGF angiogenesis cytotoxic T cells Hypoxia Immunotherapy Animals Breast Neoplasms CD8-Positive T-Lymphocytes Cell Line Tumor Cells Cultured Disease Progression Female Gene Expression Profiling Gene Expression Regulation Neoplastic Humans Hypoxia-Inducible Factor 1 alpha Subunit Mice Inbred C57BL Mice Knockout Neoplasms Experimental Neovascularization Pathologic T-Lymphocytes Cytotoxic Vascular Endothelial Growth Factor A
Carcinomas assemble a filamentous CXCL12-keratin-19 coating that suppresses T cell-mediated immune attack.
Zhikai Wang, Philip Moresco, Ran Yan, Jiayun Li, Ya Gao, Daniele Biasci, Min Yao, Jordan Pearson, Jaclyn F Hechtman, Tobias Janowitz, Raza M Zaidi, Matthew J Weiss, Douglas T Fearon
Feb 20, 2022
Cancer immunotherapy frequently fails because most carcinomas have few T cells, suggesting that cancers can suppress T cell infiltration. Here, we show that cancer cells of human pancreatic ductal adenocarcinoma (PDA)...
Does the PI3K pathway promote or antagonize regulatory T cell development and function?
Regulatory T cells (Tregs) prevent autoimmunity and inflammation by suppressing the activation of other T cells and antigen presenting cells. The role of phosphoinositide 3-kinase (PI3K) signaling in Treg is controversial. Some...
The Grizzly, February 8, 1994
Erika Compton, Hope Rinehimer, Michael Woodruff, Mark Leiser, Fred Woll, Craig Faucher, Victor Gil, Jayson Blocksidge, Richard P. Richter, Tom Epler, Sue Boyer, Ed Markowski, Kristen Cornell, Suzanne Ledonne, Harley David Rubin, Jen Diamond
Jan 01, 0001
Ursinus Celebrates 125 Years of Academics An Evaluation of the 128 Credit System In Celebration of Black History Month: Al Eaton Brings on His One-Man Show Ursinus Crimes Reported Who Freed South Africa? Guys Pledging...
Ursinus College Collegeville Pennsylvania newspaper Basketball Paul Coppola wrestling gymnastics Office of Continuing Education Wismer dining hall jazz ensemble Robert Burns Woodward Berman Art Museum Airband Reimert Hall campus security Craig Faucher Al Eaton Martin Luther King Jr. Nicholas Berry Nelson Mandela Founders Day credit policy cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Interview with Willie T. "Dub" Massey - OH 138
Willie T. Massey
Jan 01, 0001
In his April 27th, 1981 interview with Phil O'Quinn, Rev. Willie T. "Dub" Massey recollects his involvement in the Civil Rights Movement as one of the Friendship 9 protestors and non-violent activists. Massey retells the...
Friendship nine Friendship 9 Grassroots movement sit-in non-violent protests Rock Hill McCrory's discrimination Segregation Jim Crow NAACP Jail No Bail law
Published by: Winthrop University
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