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Results: 91
Vitamin D Receptor Controls Cell Stemness in Acute Myeloid Leukemia and in Normal Bone Marrow.
Etienne Paubelle, Florence Zylbersztejn, Thiago Trovati Maciel, Caroline Carvalho, Annalisa Mupo, Meyling Cheok, Liesbet Lieben, Pierre Sujobert, Justine Decroocq, Akihiko Yokoyama, Vahid Asnafi, Elizabeth Macintyre, Jérôme Tamburini, Valérie Bardet, Sylvie Castaigne, Claude Preudhomme, Hervé Dombret, Geert Carmeliet, Didier Bouscary, Yelena Z Ginzburg, Hughes de Thé, Marc Benhamou, Renato C Monteiro, George S Vassiliou, Olivier Hermine, Ivan C Moura
Feb 07, 2020
Vitamin D (VD) is a known differentiating agent, but the role of VD receptor (VDR) is still incompletely described in acute myeloid leukemia (AML), whose treatment is based mostly on antimitotic chemotherapy. Here, we present an...
acute myeloid leukemia Leukemic stem cell vitamin D receptor Animals Apoptosis Azacitidine Bone Marrow Cell Count Cell Cycle Cell Differentiation Cell Line Tumor DNA (Cytosine-5-)-Methyltransferases DNA Methylation Disease Progression Female Hematopoietic Stem Cell Transplantation Hematopoietic Stem Cells Humans Leukemia Myeloid Acute Mice Inbred C57BL Monocytes Myeloid Cells Neoplastic Stem Cells Oncogenes Promoter Regions Genetic Receptors Calcitriol Signal Transduction Survival Analysis Tumor Stem Cell Assay
Narrating the Belt and Road Education Policy
Etienne Woo
Sep 07, 2022
This article analyzes the China Belt and Road Initiative (BRI) education policy using a critical policy discourse approach. At the textual level, this paper focuses on policy framing by identifying how diagnostic (problem...
Photoplethysmography Heart Rate Monitoring
Research conducted by the World Health Organisation (WHO) in 2018 demonstrated that the worldwide threat of cardiovascular diseases (CVDs) has increased compared to previous years. CVDs are very dangerous: if timely treatment is...
Published by: IGI Global Scientific Publishing
Development of voice perception is dissociated across gender cues in school-age children.
Children's ability to distinguish speakers' voices continues to develop throughout childhood, yet it remains unclear how children's sensitivity to voice cues, such as differences in speakers' gender, develops over time. This...
Published by: Scientific reports
Quantitative monitoring and modelling of retrodialysis drug delivery in a brain phantom
Abstract A vast number of drug molecules are unable to cross the blood-brain barrier, which results in a loss of therapeutic opportunities when these molecules are administered by intravenous...
Gap variability upon packing in organic photovoltaics.
The variation of the HOMO-LUMO band gap is explored for varying packing arrangements of the 4mod BT-4TIC donor-acceptor molecule pair, by means of a high-throughput ab-initio random structure search of packing possibilities. 350...
Development of voice perception is dissociated across gender cues in school-age children.
Children's ability to distinguish speakers' voices continues to develop throughout childhood, yet it remains unclear how children's sensitivity to voice cues, such as differences in speakers' gender, develops over time. This...
Quantitative genetic analysis deciphers the impact of cis and trans regulation on cell-to-cell variability in protein expression levels
Michael D. Morgan, Etienne Patin, Bernd Jagla, Milena Hasan, Lluís Quintana-Murci, John C. Marioni
Mar 25, 2020
Identifying the factors that shape protein expression variability in complex multi-cellular organisms has primarily focused on promoter architecture and regulation of single-cell expression in cis. However, this targeted...
The draft genome of Ditylenchus dipsaci.
Benjamin Mimee, Etienne Lord, Pierre-Yves Véronneau, Rick Masonbrink, Qing Yu, Sebastian Eves-van den Akker
Jul 16, 2020
Ditylenchus dipsaci is a devastating pest to many crops worldwide. We present the first genome sequence for this species, produced with PacBio sequencing and assembled with CANU. Ditylenchus dipsaci is a devastating pest to many...
Sensing and seeing associated with overlapping occipitoparietal activation in simultaneous EEG-fMRI.
The presence of a change in a visual scene can influence brain activity and behavior, even in the absence of full conscious report. It may be possible for us to sense that such a change has occurred, even if we cannot specify...
Development of vocal emotion recognition in school-age children
Leanne Nagels, Etienne Gaudrain, Deborah Vickers, Marta Matos Lopes, Petra Hendriks, Deniz Başkent
May 11, 2020
Traditionally, emotion recognition research has primarily used pictures and videos, while audio test materials are not always readily available or are not of good quality, which may be particularly important for studies with...
Published by: PeerJ
Sensing and seeing associated with overlapping occipitoparietal activation in simultaneous EEG-fMRI.
The presence of a change in a visual scene can influence brain activity and behavior, even in the absence of full conscious report. It may be possible for us to sense that such a change has occurred, even if we cannot...
Published by: Neuroscience of consciousness
Development of vocal emotion recognition in school-age children
Leanne Nagels, Etienne Gaudrain, Deborah Vickers, Marta Matos Lopes, Petra Hendriks, Deniz Başkent
May 14, 2020
Traditionally, emotion recognition research has primarily used pictures and videos, while audio test materials are not always readily available or are not of good quality, which may be particularly important for studies with...
Surplus fat rapidly increases fat oxidation and insulin resistance in lipodystrophic mice.
Amandine Girousse, Samuel Virtue, Dan Hart, Antonio Vidal-Puig, Peter R Murgatroyd, Etienne Mouisel, Coralie Sengenès, David B Savage
Sep 05, 2018
OBJECTIVE: Surplus dietary fat cannot be converted into other macronutrient forms or excreted, so has to be stored or oxidized. Healthy mammals store excess energy in the form of triacylgycerol (TAG) in lipid droplets within...
Energy partitioning fatty acid oxidation Insulin Resistance lipodystrophy Substrate competition Adipocytes Adipose Tissue Adiposity Animals Diet High-Fat Dietary Fats Energy Intake Energy Metabolism Fatty Liver Glucose Hyperinsulinism Insulin Resistance Lipids lipodystrophy Liver Mice obesity Oxidation-Reduction Weight Gain
Quantitative genetic analysis deciphers the impact of cis and trans regulation on cell-to-cell variability in protein expression levels.
Michael D Morgan, Etienne Patin, Bernd Jagla, Milena Hasan, Lluís Quintana-Murci, John C Marioni
Mar 12, 2020
Decoding accelerometry for classification and prediction of critically ill patients with severe brain injury.
Shubhayu Bhattacharyay, John Rattray, Matthew Wang, Peter H Dziedzic, Eusebia Calvillo, Han B Kim, Eshan Joshi, Pawel Kudela, Ralph Etienne-Cummings, Robert D Stevens
Dec 24, 2021
Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control.
Isaia Barbieri, Konstantinos Tzelepis, Luca Pandolfini, Junwei Shi, Gonzalo Millán-Zambrano, Samuel C Robson, Demetrios Aspris, Valentina Migliori, Andrew J Bannister, Namshik Han, Etienne De Braekeleer, Hannes Ponstingl, Alan Hendrick, Christopher R Vakoc, George S Vassiliou, Tony Kouzarides
Feb 05, 2018
N6-methyladenosine (m6A) is an abundant internal RNA modification in both coding and non-coding RNAs that is catalysed by the METTL3-METTL14 methyltransferase complex. However, the specific role of these enzymes in cancer is...
The Adoption of Contact-Tracing Applications and the Integration of a Health Pass
Etienne Thenoz, Inès Chouk, Jean-Marc Ferrandi, Christine Gonzalez, Frantz Rowe, Béatrice Siadou-Martin
Apr 28, 2023
Contact tracing applications (CTAs) have been presented as important tools in the fight against the Covid-19 pandemic. In France, the government developed the ‘StopCovid' CTA which later became ‘TousAntiCovid.' This research...
Published by: IGI Global Scientific Publishing
Genome Expression Dynamics Reveal the Parasitism Regulatory Landscape of the Root-Knot Nematode Meloidogyne incognita and a Promoter Motif Associated with Effector Genes
Martine Da Rocha, Caroline Bournaud, Julie Dazenière, Peter Thorpe, Marc Bailly-Bechet, Clément Pellegrin, Arthur Péré, Priscila Grynberg, Laetitia Perfus-Barbeoch, Sebastian Eves-van den Akker, Etienne G. J. Danchin
May 21, 2021
Root-knot nematodes (genus Meloidogyne) are the major contributor to crop losses caused by nematodes. These nematodes secrete effector proteins into the plant, derived from two sets of pharyngeal gland cells, to manipulate host...
Social Determinants of Health Are Associated with Markers of Renal Injury in Adolescents with Type 1 Diabetes.
Laura AM Cummings, Antoine Clarke, Etienne Sochett, Denis Daneman, David Z Cherney, Heather N Reich, James W Scholey, David B Dunger, Farid H Mahmud
Sep 21, 2018
OBJECTIVE: To examine the relationship between the social determinants of health and markers of early renal injury in adolescent patients with type 1 diabetes (T1D). STUDY DESIGN: Renal outcomes included estimated glomerular...
Mitochondrial matrix-localized Src kinase regulates mitochondrial morphology
Olivier Lurette, Hala Guedouari, Jordan L. Morris, Rebeca Martín-Jiménez, Julie-Pier Robichaud, Geneviève Hamel-Côté, Mehtab Khan, Nicholas Dauphinee, Nicolas Pichaud, Julien Prudent, Etienne Hebert-Chatelain
Jun 29, 2022
Abstract: The architecture of mitochondria adapts to physiological contexts: while mitochondrial fragmentation is usually associated to quality control and cell death, mitochondrial elongation often enhances cell survival during...
Mitochondrial matrix-localized Src kinase regulates mitochondrial morphology.
Olivier Lurette, Hala Guedouari, Jordan L Morris, Rebeca Martín-Jiménez, Julie-Pier Robichaud, Geneviève Hamel-Côté, Mehtab Khan, Nicholas Dauphinee, Nicolas Pichaud, Julien Prudent, Etienne Hebert-Chatelain
Jul 01, 2022
The architecture of mitochondria adapts to physiological contexts: while mitochondrial fragmentation is usually associated to quality control and cell death, mitochondrial elongation often enhances cell survival during stress....
Gitelman syndrome: consensus and guidance from a Kidney Disease
Anne Blanchard, Detlef Bockenhauer, Davide Bolignano, Lorenzo A Calò, Etienne Cosyns, Olivier Devuyst, David H Ellison, Fiona E Karet Frankl, Nine VAM Knoers, Martin Konrad, Shih-Hua Lin, Rosa Vargas-Poussou
Feb 12, 2019
Gitelman syndrome (GS) is a rare, salt-losing tubulopathy characterized by hypokalemic metabolic alkalosis with hypomagnesemia and hypocalciuria. The disease is recessively inherited, caused by inactivating mutations in the...
SLC12A3 hypokalemic metabolic alkalosis hypomagnesemia salt-losing tubulopathy thiazide-sensitive sodium-chloride cotransporter Angiotensin Receptor Antagonists Angiotensin-Converting Enzyme Inhibitors Anti-Inflammatory Agents Non-Steroidal Bartter Syndrome Calcium Chloride Channels Chondrocalcinosis Consensus Development Conferences as Topic Diagnosis Differential Dietary Supplements Genetic Testing Gitelman syndrome Humans Hypokalemia Magnesium Mutation Phenotype Potassium Practice Guidelines as Topic Quality of life Rare Diseases Sodium Chloride Dietary Solute Carrier Family 12 Member 3 Ultrasonography
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