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Interview with Frank Ardaiolo
Frank Ardaiolo
Jan 01, 0001
In his March 9, 2015 interview with Daniel Lee, Frank Ardaiolo shares his experience with and response to Hurricane Hugo. Ardaiolo recounts the destruction on Winthrop campus and how Hurricane Hugo helped establish new emergency...
Published by: Winthrop University
Frank L. Horsfall, Jr., 1952
Frank L. Horsfall, Jr. Experiments on chemical alteration of virus infections. Lecture delivered November 20, 1952 Posted with permission
Latest Winthrop Poll is Out: This is Hillary Country
Winthrop University
Jan 01, 0001
Seventy-one percent of those surveyed said they were leaning toward voting for former Secretary of State Hillary Clinton. The other two candidates running in the primary received significantly lower support - U.S. Sen. Bernie...
Published by: Winthrop University
Frank Ardaiolo Honored with Dream Keeper Award
Winthrop University
Jan 01, 0001
Quick Facts Frank Ardaiolo, vice president for student life at Winthrop University, received the 2018 Dream Keeper Award during the city of Rock Hill's Jan. 15 Martin Luther King Jr. Interfaith Prayer Breakfast. The award...
Published by: Winthrop University
Is the Dodd-Frank Act Destroying What is Left of U.S. Thrifts?
Scott Deacle
Jan 01, 0001
I examine data from 1992 to 2015 to assess the Dodd-Frank Act's impact on the performance of U.S. depository institutions, thrifts in particular. Ceteris paribus, the average FDIC-regulated institution experienced a decline in...
Published by: Ursinus College
Frank Ardaiolo to Receive National Award from NASPA
Winthrop University
Jan 01, 0001
Frank P. Ardaiolo, vice president for student life at Winthrop, was selected as the recipient of the 2017 Scott Goodnight Award for Outstanding Performance as a Dean. Ardaiolo will be honored in March at the 2017 NASPA Annual...
Published by: Winthrop University
G-Quadruplexes
Guanine (G)-rich sequences in nucleic acids can assemble into G-quadruplex structures that involve G-quartets linked by loop nucleotides. The structural and topological diversity of G-quadruplexes have attracted great attention...
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Remote stereocontrol in [3,3]-sigmatropic rearrangements
The Ireland - Claisen [3,3]-sigmatropic rearrangement has been used to access biologically important β,β′-dihydroxy α-amino acids. The rearrangement reported is highly stereoselective and offers excellent levels of remote...
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RNA promotes phase separation of glycolysis enzymes into yeast G bodies in hypoxia.
In hypoxic stress conditions, glycolysis enzymes assemble into singular cytoplasmic granules called glycolytic (G) bodies. G body formation in yeast correlates with increased glucose consumption and cell survival. However, the...
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Remote stereocontrol in [3,3]-sigmatropic rearrangements
The Ireland - Claisen [3,3]-sigmatropic rearrangement has been used to access biologically important β,β′-dihydroxy α-amino acids. The rearrangement reported is highly stereoselective and offers excellent levels of remote...
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Modelling and simulation of biased agonism dynamics at a G protein-coupled receptor.
Theoretical models of G protein-coupled receptor (GPCR) concentration-response relationships often assume an agonist producing a single functional response via a single active state of the receptor. These models have largely...
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Amino-Acid-Derived Naphthalenediimides as Versatile G-Quadruplex Binders

The design and synthesis of water soluble, amino-acid-functionalised naphthalenediimides (NDIs) as potential ligands of native G-quadruplexes is reported. The NDIs were tested on a panel of oncogene promoters, on the human...

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Amino-Acid-Derived Naphthalenediimides as Versatile G-Quadruplex Binders

The design and synthesis of water soluble, amino-acid-functionalised naphthalenediimides (NDIs) as potential ligands of native G-quadruplexes is reported. The NDIs were tested on a panel of oncogene promoters, on the human...

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