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Interview with Betty Jean Ulmer McGregor
Betty Jean Ulmer McGregor
Jan 01, 0001
Interview with Betty Jean Ulmer McGregor, 2009 South Carolina and National Mother of the Year.
Published by: Winthrop University
The influence of two crop by-products on the hygrothermal properties of earth plasters
The incorporation of natural fibres in earth construction elements is a common practice that is found both in traditional and in contemporary building systems. The positive effect that such materials have on the mechanical...
Staggered starts in the race to T cell activation.
How T lymphocytes tune their responses to different strengths of stimulation is a fundamental question in immunology. Recent work using new optogenetic, single-cell genomic, and live-imaging approaches has revealed that...
Return to competitive gymnastics training in the UK following the first COVID-19 national lockdown
Following the outbreak of COVID-19 (coronavirus), the UK entered a national lockdown, and all sport was suspended. The study aimed to explore the process of returning to gymnastics training after several months away from the...
Modulation of antigen presenting cell functions during chronic HPV infection.
High-risk human papillomaviruses (HR-HPV) infect basal keratinocytes, where in some individuals they evade host immune responses and persist. Persistent HR-HPV infection of the cervix causes precancerous neoplasia that can...
An inverse modelling approach to estimate the hygric parameters of clay-based masonry during a Moisture Buffer Value test
This paper presents an inverse modelling approach for parameter estimation of a model dedicated to the description of moisture mass transfer in porous hygroscopic building materials. The hygric behaviour of unfired clay-based...
Imaging the Effector CD8 Synapse.
Here, we describe 4D imaging of effector CD8+ T cells as they conjugate and kill live targets in vitro and analyze the polarization dynamics of intracellular compartments to this cell-cell interface.
Conditions affecting the moisture buffering measurement performed on compressed earth blocks
Unfired clay masonry has a high potential to regulate indoor humidity and therefore create healthier living environments. The measurement of such potential on various building materials has received increasing attention and has...
Recurrent ovarian immature teratoma in a 12-year-old girl
Jenny L Frazer, C Elizabeth Hook, Helen C Addley, Claire R Jackson, John A Latimer, James C Nicholson, Matthew J Murray
May 24, 2019
Immature teratomas (IT) are rare and recurrences uncommon. A 12-year-old female with grade 3 (high-grade) ovarian IT underwent surgical resection but experienced early recurrences; the first was treated with surgery but the...
The cytotoxic T lymphocyte immune synapse at a glance.
Nele MG Dieckmann, Gordon L Frazer, Yukako Asano, Jane C Stinchcombe, Gillian M Griffiths
Sep 26, 2018
The immune synapse provides an important structure for communication with immune cells. Studies on immune synapses formed by cytotoxic T lymphocytes (CTLs) highlight the dynamic changes and specialised mechanisms required to...
Return to competitive gymnastics training in the UK following the first COVID-19 national lockdown
Following the outbreak of COVID-19 (coronavirus), the UK entered a national lockdown, and all sport was suspended. The study aimed to explore the process of returning to gymnastics training after several months away from the...
The influence of two crop by-products on the hygrothermal properties of earth plasters
The incorporation of natural fibres in earth construction elements is a common practice that is found both in traditional and in contemporary building systems. The positive effect that such materials have on the mechanical...
Conditions affecting the moisture buffering measurement performed on compressed earth blocks
Unfired clay masonry has a high potential to regulate indoor humidity and therefore create healthier living environments. The measurement of such potential on various building materials has received increasing attention and has...
A Mouse Model of Hyperproliferative Human Epithelium Validated by Keratin Profiling Shows an Aberrant Cytoskeletal Response to Injury.
Samal Zhussupbekova, Rohit Sinha, Paula Kuo, Paul F Lambert, Ian H Frazer, Zewen K Tuong
Sep 02, 2019
A validated animal model would assist with research on the immunological consequences of the chronic expression of stress keratins KRT6, KRT16, and KRT17, as observed in human pre-malignant hyperproliferative epithelium. Here we...
E7 HPV16 Hyperplasia Keratins Animals Cell Differentiation Cytoskeleton Disease Models Animal Gene Expression Human papillomavirus 16 Humans Keratin-14 Keratins Keratosis Mice Mice Inbred C57BL Mice Transgenic Microscopy Confocal Papillomavirus E7 Proteins Promoter Regions Genetic Skin Transplantation Homologous
Recruitment of Antigen Presenting Cells to Skin Draining Lymph Node From HPV16E7-Expressing Skin Requires E7-Rb Interaction.
Paula Kuo, Siok Min Teoh, Zewen K Tuong, Graham R Leggatt, Stephen R Mattarollo, Ian H Frazer
Aug 20, 2021
"High-risk" human papillomaviruses (HPV) infect keratinocytes of squamous epithelia. The HPV16E7 protein induces epithelial hyperplasia by binding Rb family proteins and disrupting cell cycle termination. Murine skin expressing...
APC CIN HPV16 Keratinocytes Retinoblastoma Protein skin grafting Animals Antigen-Presenting Cells Disease Models Animal epidermis Female Human papillomavirus 16 Humans Hyperplasia Keratinocytes Lymph Nodes Mice Mice Inbred C57BL Mice Transgenic Papillomavirus E7 Proteins Papillomavirus Infections Protein Binding Retinoblastoma Binding Proteins Retinoblastoma Protein
A SoxB gene acts as an anterior gap gene and regulates posterior segment addition in a spider.
Christian Louis Bonatto Paese, Anna Schoenauer, Daniel J Leite, Steven Russell, Alistair P McGregor
Oct 03, 2018
Sox genes encode a set of highly conserved transcription factors that regulate many developmental processes. In insects, the SoxB gene Dichaete is the only Sox gene known to be involved in segmentation. To determine if similar...
An inverse modelling approach to estimate the hygric parameters of clay-based masonry during a Moisture Buffer Value test
This paper presents an inverse modelling approach for parameter estimation of a model dedicated to the description of moisture mass transfer in porous hygroscopic building materials. The hygric behaviour of unfired clay-based...
IFN-γ Critically Enables the Intratumoural Infiltration of CXCR3+ CD8+ T Cells to Drive Squamous Cell Carcinoma Regression.
Zhen Zeng, Margaret Veitch, Gabrielle A Kelly, Zewen K Tuong, Jazmina G Cruz, Ian H Frazer, James W Wells
Jul 08, 2021
Ultraviolet (UV) radiation-induced tumours carry a high mutational load, are highly immunogenic, and often fail to grow when transplanted into normal, syngeneic mice. The aim of this study was to investigate factors critical for...
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