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How Stress Affects HU Student Study Habits
This project is meant to give people an in-depth analysis of the average HU student's study habits.(Class Project)
3rd Annual HU Research Symposium Program 2021
3rd Annual HU Research Symposium program and schedule of presenters. Presentations were held April 21st, 2021 virtually on the Teams platform.
The Hu Syndrome: At the Intersection of Cancer and Autoimmunity
Ilana J. DeLuca
Jan 01, 0001
Paraneoplastic neurologic diseases (PNDs) arise when systemic malignancies express proteins normally restricted to neurons. Abnormal expression of a neuronal protein by tumor cells in the periphery results in an autoimmune...
Published by: Rockefeller University
Development of HU Cloud-based Spark Applications for Streaming Data Analytics
Sangwhan Cha
Jan 01, 0001
Nowadays, streaming data overflows from various sources and technologies such as Internet of Things (IoT), making conventional data analytics methods unsuitable to manage the latency of data processing relative to the growing...
G-Quadruplexes
Guanine (G)-rich sequences in nucleic acids can assemble into G-quadruplex structures that involve G-quartets linked by loop nucleotides. The structural and topological diversity of G-quadruplexes have attracted great attention...
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A Study into the Ownership and Care of Animals among the HU Community
Amir Khan, Akeisha Belgrave
Jan 01, 0001
My project involves understanding the animal care routines of persons in the HU Community. (Class Project)
Remote stereocontrol in [3,3]-sigmatropic rearrangements
The Ireland - Claisen [3,3]-sigmatropic rearrangement has been used to access biologically important β,β′-dihydroxy α-amino acids. The rearrangement reported is highly stereoselective and offers excellent levels of remote...
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RNA promotes phase separation of glycolysis enzymes into yeast G bodies in hypoxia.
In hypoxic stress conditions, glycolysis enzymes assemble into singular cytoplasmic granules called glycolytic (G) bodies. G body formation in yeast correlates with increased glucose consumption and cell survival. However, the...
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Remote stereocontrol in [3,3]-sigmatropic rearrangements
The Ireland - Claisen [3,3]-sigmatropic rearrangement has been used to access biologically important β,β′-dihydroxy α-amino acids. The rearrangement reported is highly stereoselective and offers excellent levels of remote...
Published by:
Modelling and simulation of biased agonism dynamics at a G protein-coupled receptor.
Theoretical models of G protein-coupled receptor (GPCR) concentration-response relationships often assume an agonist producing a single functional response via a single active state of the receptor. These models have largely...
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Higher oxygen saturation with hydroxyurea in paediatric sickle cell disease.
INTRODUCTION: Sickle cell disease (SCD) is one of the most common inherited diseases worldwide. It is associated with lifelong morbidity and reduced life expectancy. Hydroxyurea (HU) has been shown to reduce the frequency and...
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Amino-Acid-Derived Naphthalenediimides as Versatile G-Quadruplex Binders

The design and synthesis of water soluble, amino-acid-functionalised naphthalenediimides (NDIs) as potential ligands of native G-quadruplexes is reported. The NDIs were tested on a panel of oncogene promoters, on the human...

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Amino-Acid-Derived Naphthalenediimides as Versatile G-Quadruplex Binders

The design and synthesis of water soluble, amino-acid-functionalised naphthalenediimides (NDIs) as potential ligands of native G-quadruplexes is reported. The NDIs were tested on a panel of oncogene promoters, on the human...

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