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Results: 168
Marginal zone B cells control the response of follicular helper T cells to a high-cholesterol diet
M Nus, AP Sage, Y Lu, L Masters, BYH Lam, S Newland, S Weller, D Tsiantoulas, J Raffort, D Marcus, A Finigan, L Kitt, N Figg, R Schirmbeck, M Kneilling, GSH Yeo, CJ Binder, JL de la Pompa, Z Mallat
Oct 18, 2017
Heterogeneity of hypothalamic pro-opiomelanocortin-expressing neurons revealed by single-cell RNA sequencing
BYH Lam, I Cimino, J Polex-Wolf, S Nicole Kohnke, D Rimmington, V Iyemere, N Heeley, C Cossetti, R Schulte, LR Saraiva, DW Logan, C Blouet, S O'Rahilly, AP Coll, GSH Yeo
May 08, 2017
Structural and Functional Analysis of Substrate Recognition and Inhibition of the Multidrug Transporters MRP1 and MRP2
Harlan Linver Pietz
Jan 01, 0001
Neuroblastoma is the most common extracranial tumor of young children, and the five-year overall survival of children with high-risk disease is less than 50%. Overexpression of multidrug resistance protein 1 (MRP1), a plasma...
Published by: Rockefeller University
The experience of autistic adults accessing adapted cognitive behaviour therapy
Background: High rates of depression are frequently reported in autistic adults. There have been no randomised trials investigating low-intensity psychological interventions for mild-moderate depression adapted for autistic...
adults autism spectrum disorders Cognitive behaviour therapy Depression qualitative research /dk/atira/pure/subjectarea/asjc/3200/3204 name=Developmental and Educational Psychology /dk/atira/pure/subjectarea/asjc/3200/3203 name=Clinical Psychology /dk/atira/pure/subjectarea/asjc/2700/2738 name=Psychiatry and Mental health /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Tumor Cell Glutathione Metabolism Therapeutic Implications
Bradley Alan Arrick
Jan 01, 0001
In response to oxidative injury murine tumors depend upon the GSH oxidation-reduction cycle. The susceptibility of tumor cells to lysis by a flux of H2O2, such as generated by granulocytes or activated macrophages, or by the...
Published by: Rockefeller University
The experience of autistic adults accessing adapted cognitive behaviour therapy
Background: High rates of depression are frequently reported in autistic adults. There have been no randomised trials investigating low-intensity psychological interventions for mild-moderate depression adapted for autistic...
adults autism spectrum disorders Cognitive behaviour therapy Depression qualitative research /dk/atira/pure/subjectarea/asjc/3200/3204 name=Developmental and Educational Psychology /dk/atira/pure/subjectarea/asjc/3200/3203 name=Clinical Psychology /dk/atira/pure/subjectarea/asjc/2700/2738 name=Psychiatry and Mental health /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Selenium status in diet affects acetaminophen-induced hepatotoxicity via interruption of redox environment
Jing Li, Ping Cheng, Shoufeng Li, Pengfei Zhao, Bing Han, Xiaoyuan Ren, Julia Li Zhong, Matthew D. Lloyd, Charareh Pourzand, Arne Holmgren, Jun Lu
Jun 10, 2021
Aims: Drug-induced liver injury, especially acetaminophen (APAP)-induced liver injury, is a leading cause of liver failure worldwide. Mouse models were used to evaluate the effect of microelement selenium levels on the...
acetaminophen (paracetamol) liver injury ROS selenium thioredoxin /dk/atira/pure/subjectarea/asjc/1300/1314 name=Physiology /dk/atira/pure/subjectarea/asjc/1300/1303 name=Biochemistry /dk/atira/pure/subjectarea/asjc/1300/1312 name=Molecular Biology /dk/atira/pure/subjectarea/asjc/1300/1308 name=Clinical Biochemistry /dk/atira/pure/subjectarea/asjc/1300/1307 name=Cell Biology
The feasibility of low intensity psychological therapy for co-occurring depression in adult Autism
Ailsa Russell, Daisy Gaunt, Kate Cooper, Stephen Barton, Jeremy Horwood, David Kessler, Chris Metcalfe, Ian Ensum, Barry Ingham, Jeremy R. Parr, Dheeraj Rai, Nicola Wiles
Aug 01, 2020
Low intensity cognitive behaviour therapy (CBT) including behavioural activation is an evidence based treatment for depression, a condition frequently co-occurring with autism. The feasibility of adapting low intensity CBT for...
Prolonged depletion of antioxidant capacity after ultraendurance exercise
The purpose of this study was to examine the short- and long-term (up to 1 month) effects of an ultraendurance running event on redox homeostasis. Markers of oxidative stress and antioxidant capacity in peripheral blood were...
The feasibility of low intensity psychological therapy for co-occurring depression in adult Autism
Ailsa Russell, Daisy Gaunt, Kate Cooper, Stephen Barton, Jeremy Horwood, David Kessler, Chris Metcalfe, Ian Ensum, Barry Ingham, Jeremy R. Parr, Dheeraj Rai, Nicola Wiles
Aug 01, 2020
Low intensity cognitive behaviour therapy (CBT) including behavioural activation is an evidence based treatment for depression, a condition frequently co-occurring with autism. The feasibility of adapting low intensity CBT for...
Is calorie labelling on menus the solution to obesity?
Giles SH Yeo
Jul 10, 2022
From April 2022, as part of the UK government’s new obesity strategy, it is now compulsory for all larger restaurant and cafes in the UK to include calorie labelling on their menus. Is this legislation, however, likely to be...
Selenium status in diet affects acetaminophen-induced hepatotoxicity via interruption of redox environment
Jing Li, Ping Cheng, Shoufeng Li, Pengfei Zhao, Bing Han, Xiaoyuan Ren, Julia Li Zhong, Matthew D. Lloyd, Charareh Pourzand, Arne Holmgren, Jun Lu
Jun 10, 2021
Aims: Drug-induced liver injury, especially acetaminophen (APAP)-induced liver injury, is a leading cause of liver failure worldwide. Mouse models were used to evaluate the effect of microelement selenium levels on the...
acetaminophen (paracetamol) liver injury ROS selenium thioredoxin /dk/atira/pure/subjectarea/asjc/1300/1314 name=Physiology /dk/atira/pure/subjectarea/asjc/1300/1303 name=Biochemistry /dk/atira/pure/subjectarea/asjc/1300/1312 name=Molecular Biology /dk/atira/pure/subjectarea/asjc/1300/1308 name=Clinical Biochemistry /dk/atira/pure/subjectarea/asjc/1300/1307 name=Cell Biology
The regressive power of labels of vulnerability affecting disabled asylum seekers in the UK
Rebecca Amani Yeo
Jan 01, 0001
There has been some progress in the United Kingdom regarding official recognition of the existence and needs of disabled asylum seekers and refugees. However, references are commonly accompanied by euphemistic labels...
The regressive power of labels of vulnerability affecting disabled asylum seekers in the UK
Rebecca Amani Yeo
Jan 01, 0001
There has been some progress in the United Kingdom regarding official recognition of the existence and needs of disabled asylum seekers and refugees. However, references are commonly accompanied by euphemistic labels...
Prolonged depletion of antioxidant capacity after ultraendurance exercise
The purpose of this study was to examine the short- and long-term (up to 1 month) effects of an ultraendurance running event on redox homeostasis. Markers of oxidative stress and antioxidant capacity in peripheral blood were...
The Role of Kiss1 Neurons As Integrators of Endocrine, Metabolic, and Environmental Factors in the Hypothalamic-Pituitary-Gonadal Axis.
Kisspeptin-GPR54 signaling in the hypothalamus is required for reproduction and fertility in mammals. Kiss1 neurons are key regulators of gonadotropin-releasing hormone (GnRH) release and modulation of the...
The genetics of obesity
The prevalence of obesity has tripled over the past four decades, imposing an enormous burden on people's health. Polygenic (or common) obesity and rare, severe, early-onset monogenic obesity are often polarized as distinct...
Exploratory Study of Societal Contexts and Industry Performance
There is inconclusive evidence on the effectiveness of information and communication technologies (ICT) at the industry level. Using the influence-impact model as a theoretical framework, the authors apply data mining techniques...
Published by: IGI Global Scientific Publishing
Are ICTs Really That Important in Driving Industry Performance?
A decision tree is used to investigate how information and communication technologies (ICTs) and financial factors influence the performance of service and manufacturing industries globally. Industry performance is measured by...
Published by: IGI Global Scientific Publishing
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