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Gene Ontology Consortium
Gene Ontology Consortium
May 06, 2020
The Gene Ontology (GO; http://www.geneontology.org) is a community-based bioinformatics resource that supplies information about gene product function using ontologies to represent biological knowledge. Here we describe...
The Gene Ontology resource
Gene Ontology Consortium
Feb 08, 2021
The Gene Ontology Consortium (GOC) provides the most comprehensive resource currently available for computable knowledge regarding the functions of genes and gene products. Here, we report the advances of the consortium over the...
The Gene Ontology Resource
The Gene Ontology Consortium
Feb 11, 2019
The Gene Ontology resource (GO; http://geneontology.org) provides structured, computable knowledge regarding the functions of genes and gene products. Founded in 1998, GO has become widely adopted in the life sciences, and its...
The Gene Ontology
Gene Ontology Consortium
May 06, 2020
The Gene Ontology (GO) (http://www.geneontology.org) is a community bioinformatics resource that represents gene product function through the use of structured, controlled vocabularies. The number of GO annotations of gene...
The Gene Ontology in 2010
Gene Ontology Consortium
May 06, 2020
The Gene Ontology (GO) Consortium (http://www.geneontology.org) (GOC) continues to develop, maintain and use a set of structured, controlled vocabularies for the annotation of genes, gene products and sequences. The GO...
The Gene Ontology project in 2008.
Gene Ontology Consortium
May 06, 2020
The Gene Ontology (GO) project (http://www.geneontology.org/) provides a set of structured, controlled vocabularies for community use in annotating genes, gene products and sequences (also see http://www.sequenceontology.org/)....
The Gene Ontology (GO) project in 2006.
Gene Ontology Consortium
May 06, 2020
The Gene Ontology (GO) project (http://www.geneontology.org) develops and uses a set of structured, controlled vocabularies for community use in annotating genes, gene products and sequences (also see...
The Gene Ontology's Reference Genome Project
The Gene Ontology (GO) is a collaborative effort that provides structured vocabularies for annotating the molecular function, biological role, and cellular location of gene products in a highly systematic way and in a...
Predicting and Visualizing Lateral Movements Based on ATT&CK and Quantification Theory Type 3
When a cyber incident occurs, organizations need to identify the attack's impacts. They have to investigate potentially infected devices as well as certainly infected devices. However, as an organization's network expands, it is...
Published by: IGI Global Scientific Publishing
Effector gene birth in plant parasitic nematodes
Catherine J Lilley, Abbas Maqbool, Duqing Wu, Hazijah B Yusup, Laura M Jones, Paul RJ Birch, Mark J Banfield, Peter E Urwin, Sebastian Eves-van den Akker
Oct 10, 2018
Plant pathogens and parasites are a major threat to global food security. Plant parasitism has arisen four times independently within the phylum Nematoda, resulting in at least one parasite of every major food crop in the world....
Comment on Herring et al. The Use of "Retardation" in FRAXA, FMRP, FMR1 and Other Designations. Cells 2022, 11, 1044.
This commentary is written in response to the recent article from Herring et al., discussing the eradication of the offensive term "retardation" from gene nomenclature. We discuss the work of the HUGO (Human Genome Organisation)...
Cytokinin is required for escape but not release from auxin mediated apical dominance.
Dörte Müller, Tanya Waldie, Kaori Miyawaki, Jennifer PC To, Charles W Melnyk, Joseph J Kieber, Tatsuo Kakimoto, Ottoline Leyser
Apr 23, 2021
Auxin produced by an active primary shoot apex is transported down the main stem and inhibits the growth of the axillary buds below it, contributing to apical dominance. Here we use Arabidopsis thaliana cytokinin (CK)...
Arabidopsis thaliana Isopentenyltransferase apical dominance Auxin cytokinin Shoot branching type-A Arabidopsis response regulators Alkyl and Aryl Transferases Arabidopsis Arabidopsis Proteins Cytokinins Gene Expression Regulation Plant Indoleacetic Acids Multigene Family Mutation Nitrates Plant Shoots Transcription Factors
Association of creatine kinase and skin toxicity in phase I trials of anticancer agents.
V Moreno Garcia, P Thavasu, M Blanco Codesido, LR Molife, J Vitfell Pedersen, M Puglisi, B Basu, K Shah, J Iqbal, JS de Bono, SB Kaye, U Banerji
Sep 25, 2020
BACKGROUND: We investigated the association between skin rash and plasma creatine kinase (CK) levels in oncology phase I trials. METHODS: We analysed data from 295 patients treated at our institution within 25 phase I trials...
Temperature Sensitivity
Sarah Keep, Phoebe Stevenson-Leggett, Angela Steyn, Michael S Oade, Isobel Webb, Jamie Stuart, Lonneke Vervelde, Paul Britton, Helena J Maier, Erica Bickerton
Jul 17, 2020
The Gammacoronavirus infectious bronchitis virus (IBV) is a highly contagious economically important respiratory pathogen of domestic fowl. Reverse genetics allows for the molecular study of pathogenic determinants to enable...
Transcriptional coupling of neighboring genes and gene expression noise
How is noise in gene expression modulated? Do mechanisms of noise control impact genome organization? In yeast, the expression of one gene can affect that of a very close neighbor. As the effect is highly regionalized, we...
Charcot knee - presentation, diagnosis, management - a scoping review.
Background
Charcot arthropathy is a progressive, non-infectious, destructive inflammatory process. Charcot arthropathy of the knee (CK) is rare and diagnosis is often delayed, resulting in detrimental outcomes. This...
Published by: Clinical rheumatology
Transcriptional coupling of neighboring genes and gene expression noise
How is noise in gene expression modulated? Do mechanisms of noise control impact genome organization? In yeast, the expression of one gene can affect that of a very close neighbor. As the effect is highly regionalized, we...
Annotation of gene product function from high-throughput studies using the Gene Ontology.
Helen Attrill, Pascale Gaudet, Rachael P Huntley, Ruth C Lovering, Stacia R Engel, Sylvain Poux, Kimberly M Van Auken, George Georghiou, Marcus C Chibucos, Tanya Z Berardini, Valerie Wood, Harold Drabkin, Petra Fey, Penelope Garmiri, Midori A Harris, Tony Sawford, Leonore Reiser, Rebecca Tauber, Sabrina Toro, Gene Ontology Consortium
Feb 14, 2019
High-throughput studies constitute an essential and valued source of information for researchers. However, high-throughput experimental workflows are often complex, with multiple data sets that may contain large numbers of false...
Hydra
Jacob Pfeil, Lauren M Sanders, Ioannis Anastopoulos, A Geoffrey Lyle, Alana S Weinstein, Yuanqing Xue, Andrew Blair, Holly C Beale, Alex Lee, Stanley G Leung, Phuong T Dinh, Avanthi Tayi Shah, Marcus R Breese, W Patrick Devine, Isabel Bjork, Sofie R Salama, E Alejandro Sweet-Cordero, David Haussler, Olena Morozova Vaske
Apr 22, 2020
Precision oncology has primarily relied on coding mutations as biomarkers of response to therapies. While transcriptome analysis can provide valuable information, incorporation into workflows has been difficult. For example, the...
Transcription-coupled repair and mismatch repair contribute towards preserving genome integrity at mononucleotide repeat tracts
Ilias Georgakopoulos-Soares, Gene Koh, Sophie E. Momen, Josef Jiricny, Martin Hemberg, Serena Nik-Zainal
Apr 24, 2021
Abstract: The mechanisms that underpin how insertions or deletions (indels) become fixed in DNA have primarily been ascribed to replication-related and/or double-strand break (DSB)-related processes. Here, we introduce a method...
CEERS Key Paper. I. An Early Look into the First 500 Myr of Galaxy Formation with JWST
Stephen Wilkins, Darren J. Croton, Emanuele Daddi, Avishai Dekel, David Elbaz, Maximilien Franco, Eric Gawiser, Benne W. Holwerda, Marc Huertas-Company, Anne Jaskot, Gene Leung, Ray A. Lucas, Bahram Mobasher, Viraj Pandya, Sandro Tacchella, Benjamin J. Weiner, Jorge A. Zavala
Mar 27, 2023
We present an investigation into the first 500 Myr of galaxy evolution from the Cosmic Evolution Early Release Science (CEERS) survey. CEERS, one of 13 JWST ERS programs, targets galaxy formation from z ∼ 0.5 to >10 using...
Charcot knee - presentation, diagnosis, management - a scoping review.
BACKGROUND: Charcot arthropathy is a progressive, non-infectious, destructive inflammatory process. Charcot arthropathy of the knee (CK) is rare and diagnosis is often delayed, resulting in detrimental outcomes. This scoping...
Charcot knee — presentation, diagnosis, management — a scoping review
Abstract: Background: Charcot arthropathy is a progressive, non-infectious, destructive inflammatory process. Charcot arthropathy of the knee (CK) is rare and diagnosis is often delayed, resulting in detrimental outcomes. This...
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