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Abstract: It is quite common that the structure of a time series changes abruptly. Identifying these change points and describing the model structure in the segments between these change points is of interest. In this paper...

Regular Article Changepoint detection Autoregressive time series Likelihood ratio scan statistics Multiple testing problems

It is quite common that the structure of a time series changes abruptly. Identifying these change points and describing the model structure in the segments between these change points is of interest. In this paper, time series...

Autoregressive time series Changepoint detection Likelihood ratio scan statistics Multiple testing problems

Abstract: It is quite common that the structure of a time series changes abruptly. Identifying these change points and describing the model structure in the segments between these change points is of interest. In this paper...

Regular Article Changepoint detection Autoregressive time series Likelihood ratio scan statistics Multiple testing problems

The expression profile of a gene is controlled by DNA sequences called cis-regulatory modules (CRMs). CRMs can function over large genomic distances and can be located many kilobases away from their target promoters. hes1 is...

Animals Basic Helix-Loop-Helix Transcription Factors Cell Line Computational Biology Conserved Sequence Enhancer Elements Genetic Gene Expression Regulation Homeodomain Proteins Immunoglobulin J Recombination Signal Sequence-Binding Protein Mice Myoblasts Nucleotide Motifs Promoter Regions Genetic Receptors Notch Regulatory Sequences Nucleic Acid Signal Transduction Transcription Initiation Site /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being

The expression profile of a gene is controlled by DNA sequences called cis-regulatory modules (CRMs). CRMs can function over large genomic distances and can be located many kilobases away from their target promoters. hes1 is...

Animals Basic Helix-Loop-Helix Transcription Factors Cell Line Computational Biology Conserved Sequence Enhancer Elements Genetic Gene Expression Regulation Homeodomain Proteins Immunoglobulin J Recombination Signal Sequence-Binding Protein Mice Myoblasts Nucleotide Motifs Promoter Regions Genetic Receptors Notch Regulatory Sequences Nucleic Acid Signal Transduction Transcription Initiation Site /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being

MOTIVATION: cis-regulatory DNA sequence elements, such as enhancers and silencers, function to control the spatial and temporal expression of their target genes. Although the overall levels of gene expression in large cell...

Algorithms Animals Bayes Theorem Cell Line Enhancer Elements Genetic Gene Dosage MSX1 Transcription Factor Mice Models Genetic Promoter Regions Genetic Single-Cell Analysis Transcription Genetic

Mesoscale eddies have strong signatures in sea surface height (SSH) anomalies that are measured globally through satellite altimetry. However, monitoring the transport of heat associated with these eddies and its impact on the...

14 Life Below Water

MOTIVATION: cis-regulatory DNA sequence elements, such as enhancers and silencers, function to control the spatial and temporal expression of their target genes. Although the overall levels of gene expression in large cell...

Algorithms Animals Bayes Theorem Cell Line Enhancer Elements Genetic Gene Dosage MSX1 Transcription Factor Mice Models Genetic Promoter Regions Genetic Single-Cell Analysis Transcription Genetic

The process of transcription is highly stochastic leading to cell-to-cell variations and noise in gene expression levels. However, key essential genes have to be precisely expressed at the correct amount and time to ensure...

The process of transcription is highly stochastic leading to cell-to-cell variations and noise in gene expression levels. However, key essential genes have to be precisely expressed at the correct amount and time to ensure...

The extraction of fluorescence time course data is a major bottleneck in high-throughput live-cell microscopy. Here we present an extendible framework based on the open-source image analysis software ImageJ, which aims in...

Animals biological markers Cell Division Cell Line Cell Lineage Cell Nucleus Cell Tracking Fluorescence Genes Reporter Green Fluorescent Proteins High-Throughput Screening Assays Imaging Three-Dimensional Mice Microscopy Time Factors Zebrafish

The extraction of fluorescence time course data is a major bottleneck in high-throughput live-cell microscopy. Here we present an extendible framework based on the open-source image analysis software ImageJ, which aims in...

Animals biological markers Cell Division Cell Line Cell Lineage Cell Nucleus Cell Tracking Fluorescence Genes Reporter Green Fluorescent Proteins High-Throughput Screening Assays Imaging Three-Dimensional Mice Microscopy Time Factors Zebrafish