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Results: 73
Enhancer-associated H3K4 methylation safeguards in vitro germline competence.
Tore Bleckwehl, Giuliano Crispatzu, Kaitlin Schaaf, Patricia Respuela, Michaela Bartusel, Laura Benson, Stephen J Clark, Kristel M Dorighi, Antonio Barral, Magdalena Laugsch, Wilfred FJ van IJcken, Miguel Manzanares, Joanna Wysocka, Wolf Reik, Álvaro Rada-Iglesias
Nov 02, 2021
Animals Cell Differentiation Chromatin Embryo Mammalian Enhancer Elements Genetic Gene Expression Regulation Germ Cells Germ Layers Histones Lysine Male Methylation Mice Mice Transgenic Mouse embryonic stem cells Mutation Otx Transcription Factors RNA-seq Single-Cell Analysis Transcription Initiation Site Transcription Genetic
Enhancer-associated H3K4 methylation safeguards in vitro germline competence
Tore Bleckwehl, Giuliano Crispatzu, Kaitlin Schaaf, Patricia Respuela, Michaela Bartusel, Laura Benson, Stephen J. Clark, Kristel M. Dorighi, Antonio Barral, Magdalena Laugsch, Wilfred F. J. van IJcken, Miguel Manzanares, Joanna Wysocka, Wolf Reik, Álvaro Rada-Iglesias
Oct 01, 2021
Clinical response and survival time of cats with carcinoma of the nasal cavity treated with palliative coarse fractionated radiotherapy.
OBJECTIVES: Carcinoma is the second most common tumour of the nasal cavity in cats. Few studies assessing the response and survival of cats with carcinoma of the nasal cavity treated with palliative coarse fractionated...
COVID-19 vaccine hesitancy in Sweden and Italy
BACKGROUND: The success of vaccination campaigns against COVID-19 infection is vital for moving from a COVID-19 pandemic to an endemic scenario. We aimed to unravel the influence of the risk perception of epidemics along with...
Prospective clinical trial of masitinib mesylate treatment for advanced stage III and IV canine malignant melanoma.
OBJECTIVE: To investigate efficacy of masitinib mesylate for the treatment of advanced malignant melanoma in dogs. MATERIALS AND METHODS: Prospective clinical trial on 17 dogs with stage III and IV malignant melanoma (two...
Addictive behaviour in experimental animals
Since the introduction of intravenous drug self-administration methodology over 50 years ago, experimental investigation of addictive behaviour has delivered an enormous body of data on the neural, psychological and molecular...
Do the Benefits of School Closure Outweigh Its Costs?
School closure has been a common response to COVID-19. Yet, its implementation has hardly ever been based on rigorous analysis of its costs and benefits. We aim to first illustrate the unintended consequences and side effects of...
Individual differences in the engagement of habitual control over alcohol seeking predict the development of compulsive alcohol seeking and drinking.
Excessive drinking is an important behavioural characteristic of alcohol addiction, but not the only one. Individuals addicted to alcohol crave alcoholic beverages, spend time seeking alcohol despite negative consequences and...
Cancer-Related Mutations Are Not Enriched in Naive Human Pluripotent Stem Cells.
Capacitation of human naïve pluripotent stem cells for multi-lineage differentiation.
Compulsive Alcohol Seeking Results from a Failure to Disengage Dorsolateral Striatal Control over Behavior.
The Cell-Surface Marker Sushi Containing Domain 2 Facilitates Establishment of Human Naive Pluripotent Stem Cells.
Nicholas Bredenkamp, Giuliano Giuseppe Stirparo, Jennifer Nichols, Austin Smith, Ge Guo
Apr 05, 2019
Basolateral and central amygdala differentially recruit and maintain dorsolateral striatum-dependent cocaine-seeking habits.
Jennifer E Murray, Aude Belin-Rauscent, Marine Simon, Chiara Giuliano, Marianne Benoit-Marand, Barry J Everitt, David Belin
Oct 07, 2015
Repurposing Drugs in Small Animal Oncology.
Repurposing drugs in oncology consists of using off-label drugs that are licensed for various non-oncological medical conditions to treat cancer. Repurposing drugs has the advantage of using drugs that are already...
Integrated analysis of single-cell embryo data yields a unified transcriptome signature for the human pre-implantation epiblast.
Giuliano G Stirparo, Thorsten Boroviak, Ge Guo, Jennifer Nichols, Austin Smith, Paul Bertone
Mar 08, 2018
Cross-regulation between Aurora B and Citron kinase controls midbody architecture in cytokinesis.
Callum McKenzie, Zuni I Bassi, Janusz Debski, Marco Gottardo, Giuliano Callaini, Michal Dadlez, Pier Paolo D'Avino
Feb 26, 2016
A possible role of coarse fractionated radiotherapy in the management of gingival squamous cell carcinoma in dogs
Surgery with or without the addition of radiotherapy is the treatment of choice for canine oral squamous cell carcinoma (SCC). Fractionated radiotherapy alone is also effective in the long-term control of the disease, however...
Individual differences in the engagement of habitual control over alcohol seeking predict the development of compulsive alcohol seeking and drinking
Abstract: Excessive drinking is an important behavioural characteristic of alcohol addiction, but not the only one. Individuals addicted to alcohol crave alcoholic beverages, spend time seeking alcohol despite negative...
Original Article Original Articles Alcohol Compulsivity Contingency degradation devaluation Quinine seeking
Published by: Addiction Biology
Alcohol-Preferring Rats Show Goal Oriented Behaviour to Food Incentives but Are Neither Sign-Trackers Nor Impulsive.
Yolanda Peña-Oliver, Chiara Giuliano, Daina Economidou, Charles R Goodlett, Trevor W Robbins, Jeffrey W Dalley, Barry J Everitt
Jun 23, 2015
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