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Results: 47
BRCA2 controls DNA
Giuseppina D'Alessandro, Donna Rose Whelan, Sean Michael Howard, Valerio Vitelli, Xavier Renaudin, Marek Adamowicz, Fabio Iannelli, Corey Winston Jones-Weinert, MiYoung Lee, Valentina Matti, Wei Ting C Lee, Michael John Morten, Ashok Raraakrishnan Venkitaraman, Petr Cejka, Eli Rothenberg, Fabrizio d'Adda di Fagagna
Feb 08, 2019
DNA double-strand breaks (DSBs) are toxic DNA lesions, which, if not properly repaired, may lead to genomic instability, cell death and senescence. Damage-induced long non-coding RNAs (dilncRNAs) are transcribed from broken DNA...
Being in a loop
Chromatin architecture has a significant impact on gene expression. Evidence in the last two decades support RNA as an important component of chromatin structure [Genes Dev. (2005) 19, 1635–1655; PLoS ONE (2007) 2, e1182; Nat....
Being in a loop
Chromatin architecture has a significant impact on gene expression. Evidence in the last two decades support RNA as an important component of chromatin structure [Genes Dev. (2005) 19, 1635–1655; PLoS ONE (2007) 2, e1182; Nat....
Possessivi e partitivi nei dialetti italo-romanzi dell'Area Lausberg
Giuseppina Silvestri
Aug 19, 2019
L’ampia variazione morfologica e sintattica, che caratterizza i possessivi nelle varietà
italo-romanze non standard, non è stata oggetto finora di un’osservazione attenta
e continua. Vi sono tuttavia delle eccezioni : si pensi...
Published by: La lingua italiana. Storia, Struttura, Testi
Nanoparticles for Drug and Gene Delivery in Pediatric Brain Tumors' Cancer Stem Cells
Luana Abballe, Zaira Spinello, Celeste Antonacci, Lucia Coppola, Ermanno Miele, Giuseppina Catanzaro, Evelina Miele
Mar 28, 2023
Primary malignant brain tumors are the most common solid neoplasm in childhood. Despite recent advances, many children affected by aggressive or metastatic brain tumors still present poor prognosis, therefore the development of...
Published by: Pharmaceutics
Near critical, self-similar, blow-up solutions of the generalised Korteweg–de Vries equation
Pierluigi Amodio, Chris J. Budd, Othmar Koch, Vivi Rottschäfer, Giuseppina Settanni, Ewa Weinmüller
Jan 01, 2020
In this article we give a detailed asymptotic analysis of the near critical self-similar blowup solutions to the Generalised Korteweg–de Vries equation (GKdV). We compare this analysis to some careful numerical calculations....
Asymptotic analysis Blow-up solutions Generalised Korteweg–de Vries equation Numerical methods /dk/atira/pure/subjectarea/asjc/3100/3109 name=Statistical and Nonlinear Physics /dk/atira/pure/subjectarea/asjc/2600/2610 name=Mathematical Physics /dk/atira/pure/subjectarea/asjc/3100/3104 name=Condensed Matter Physics /dk/atira/pure/subjectarea/asjc/2600/2604 name=Applied Mathematics
Near critical, self-similar, blow-up solutions of the generalised Korteweg–de Vries equation
Pierluigi Amodio, Chris J. Budd, Othmar Koch, Vivi Rottschäfer, Giuseppina Settanni, Ewa Weinmüller
Jan 01, 2020
In this article we give a detailed asymptotic analysis of the near critical self-similar blowup solutions to the Generalised Korteweg–de Vries equation (GKdV). We compare this analysis to some careful numerical calculations....
Asymptotic analysis Blow-up solutions Generalised Korteweg–de Vries equation Numerical methods /dk/atira/pure/subjectarea/asjc/3100/3109 name=Statistical and Nonlinear Physics /dk/atira/pure/subjectarea/asjc/2600/2610 name=Mathematical Physics /dk/atira/pure/subjectarea/asjc/3100/3104 name=Condensed Matter Physics /dk/atira/pure/subjectarea/asjc/2600/2604 name=Applied Mathematics
Music perception and speech intelligibility in noise performance by Italian-speaking cochlear implant users.
Linking defects, hierarchical porosity generation and desalination performance in metal-organic frameworks.
Weibin Liang, Lin Li, Jingwei Hou, Nicholas D Shepherd, Thomas D Bennett, Deanna M D'Alessandro, Vicki Chen
Oct 10, 2018
Composite membranes with defective metal-organic frameworks (MOFs) connect the emerging fields of MOF topological modification, MOF-polymer interfacial engineering and composite material functionalization. Although defective...
MicroRNA-155 is essential for the optimal proliferation and survival of plasmablast B cells.
Giuseppina Arbore, Tom Henley, Laura Biggins, Simon Andrews, Elena Vigorito, Martin Turner, Rebecca Leyland
Jul 18, 2019
A fast antibody response can be critical to contain rapidly dividing pathogens. This can be achieved by the expansion of antigen-specific B cells in response to T-cell help followed by differentiation into plasmablasts....
MicroRNA-155 controls affinity-based selection by protecting c-MYC+ B cells from apoptosis.
Rinako Nakagawa, Rebecca Leyland, Michael Meyer-Hermann, Dong Lu, Martin Turner, Giuseppina Arbore, Tri Giang Phan, Robert Brink, Elena Vigorito
May 24, 2019
Pregnancy insulin, glucose, and BMI contribute to birth outcomes in nondiabetic mothers.
Ken K Ong, Barbro Diderholm, Giuseppina Salzano, Dianne Wingate, Ieuan A Hughes, Jane MacDougall, Carlo L Acerini, David B Dunger
Feb 21, 2020
OBJECTIVE: We investigated the effects of normal variations in maternal glycemia on birth size and other birth outcomes. RESEARCH DESIGN AND METHODS: Women in two unselected birth cohorts, one retrospective (n = 3,158) and one...
Hybrid Fly Ash-Based Geopolymeric Foams
Giuseppina roviello, Laura Ricciotti, Antonio Jacopo Molino, Constantino Menna, Claudio Ferone, Domenico Asprone, Raffaele Cioffi, Veronica Ferrandiz-Mas, Pietro Russo, Oreste Tarallo
Jun 29, 2020
This research investigates the preparation and characterization of new organic–inorganic geopolymeric foams obtained by simultaneously reacting coal fly ash and an alkali silicate solution with polysiloxane oligomers. Foaming...
Peptide-modified liposomes for selective targeting of bombesin receptors overexpressed by cancer cells
Antonella Accardo, Giuseppina Salsano, Anna Morisco, Michela Aurilio, Antonio Parisi, Francesco Maione, Carla Cicala, Diego Tesauro, Luigi Aloj, Giuseppe De Rosa, Giancarlo Morelli
Dec 21, 2018
OBJECTIVES: Drug delivery systems consisting of liposomes displaying a cell surface receptor-targeting peptide are being developed to specifically deliver chemotherapeutic drugs to tumors overexpressing a target receptor. This...
PC-3 Cells bombesin peptide doxorubicin delivery gastrin-releasing peptide receptors theranostic applications Animals Antineoplastic Agents Bombesin Cell Line Tumor Doxorubicin Drug Carriers Drug Delivery Systems Female Humans Liposomes Male Mice Mice Inbred BALB C Mice Nude nanomedicine Pentetic Acid Peptide Fragments Phosphatidylcholines Prostatic Neoplasms Receptors Bombesin Surface-Active Agents Xenograft Model Antitumor Assays
Plasma from pre-pubertal obese children impairs insulin stimulated Nitric Oxide (NO) bioavailability in endothelial cells
Natalia Di Pietro, M Loredana Marcovecchio, Sara Di Silvestre, Tommaso de Giorgis, Vincenzo Giuseppe Pio Cordone, Paola Lanuti, Francesco Chiarelli, Giuseppina Bologna, Angelika Mohn, Assunta Pandolfi
Aug 01, 2018
Childhood obesity is commonly associated with early signs of endothelial dysfunction, characterized by impairment of insulin signaling and vascular Nitric Oxide (NO) availability. However, the underlying mechanisms remain to be...
ER stress Endothelial dysfunction Insulin Resistance Nitric oxide obesity Activating Transcription Factor 6 Biological Availability Biomarkers Cell Nucleus Child Cyclic GMP Endoplasmic Reticulum Chaperone BiP Endoplasmic reticulum stress Human Umbilical Vein Endothelial Cells Humans Insulin Models Biological NF-kappa B Nitric oxide Nitric Oxide Synthase Type III obesity Phosphorylation Protein Transport Proto-Oncogene Proteins c-akt Puberty
Chromatin interaction maps identify Wnt responsive cis-regulatory elements coordinating Paupar-Pax6 expression in neuronal cells
Ioanna Pavlaki, Michael Shapiro, Giuseppina Pisignano, Steph Jones, Jelena Telenius, Silvia Munoz-Descalzo, Robert J Williams, Jim R. Hughes, Keith Vance
Jun 16, 2022
Central nervous system-expressed long non-coding RNAs (lncRNAs) are often located in the genome close to protein coding genes involved in transcriptional control. Such lncRNA-protein coding gene pairs are frequently temporally...
The Conundrum of Cancer-Associated Thrombosis
Simona Laurino, Sabino Russ, Ludmila Carmen Omer, Alberto D'Angelo, Giovanni Bozza, Giuseppina Gallucci, Geppino Falco, Giandomenico Roviello, Anna Maria Bochicchio
Mar 31, 2024
The correlation between cancer and venous thromboembolism (VTE) is solid, whereas the knowledge about cancer-related arterial thromboembolism (ATE) still needs a deeper investigation to clarify its pathogenesis. We describe two...
arterial thromboembolism (ATE) cancer patients cancer-associated thrombosis (CAT) mechanisms of thrombosis reverse cardio-oncology thrombophilic status of cancer patients Venous thromboembolism (VTE) /dk/atira/pure/subjectarea/asjc/2700/2700 name=General Medicine /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Chromatin interaction maps identify Wnt responsive cis-regulatory elements coordinating Paupar-Pax6 expression in neuronal cells
Ioanna Pavlaki, Michael Shapiro, Giuseppina Pisignano, Steph Jones, Jelena Telenius, Silvia Munoz-Descalzo, Robert J Williams, Jim R. Hughes, Keith Vance
Jun 16, 2022
Central nervous system-expressed long non-coding RNAs (lncRNAs) are often located in the genome close to protein coding genes involved in transcriptional control. Such lncRNA-protein coding gene pairs are frequently temporally...
Hybrid Fly Ash-Based Geopolymeric Foams
Giuseppina roviello, Laura Ricciotti, Antonio Jacopo Molino, Constantino Menna, Claudio Ferone, Domenico Asprone, Raffaele Cioffi, Veronica Ferrandiz-Mas, Pietro Russo, Oreste Tarallo
Jun 29, 2020
This research investigates the preparation and characterization of new organic–inorganic geopolymeric foams obtained by simultaneously reacting coal fly ash and an alkali silicate solution with polysiloxane oligomers. Foaming...
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