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Results: 39
A De Novo Mouse Model of C11orf95-RELA Fusion-Driven Ependymoma Identifies Driver Functions in Addition to NF-κB.
Tatsuya Ozawa, Sonali Arora, Frank Szulzewsky, Gordana Juric-Sekhar, Yoshiteru Miyajima, Hamid Bolouri, Yoshie Yasui, Jason Barber, Robert Kupp, James Dalton, Terreia S Jones, Mitsutoshi Nakada, Toshihiro Kumabe, David W Ellison, Richard J Gilbertson, Eric C Holland
Sep 21, 2018
The majority of supratentorial ependymomas (ST-ependymomas) have few mutations but frequently display chromothripsis of chromosome 11q that generates a fusion between C11orf95 and RELA (RELAFUS). Neural stem cells transduced...
A Review of Spectrum Sensing Techniques Based on Machine Learning
This article presents a survey of current spectrum sensing (SS) research involving the application of image processing and deep learning techniques. This document includes approaches to narrowband, wideband, and cooperative SS....
Global Information Technology Computer Science and Information Technology Global Information Technology Physical Sciences and Engineering Business and Management
Published by: IGI Global Scientific Publishing
A numerical investigation of three-dimensional falling liquid films
Abstract In this article, we present a full three-dimensional numerical study of thin liquid films falling on a vertical surface, by solving the full three-dimensional Navier–Stokes equations with...
Lyes Kahouadji, Assen Batchvarov, Idris T Adebayo, Zachary Jenkins, Seungwon Shin, Jalel Chergui, Damir Juric, Omar K Matar
Jun 07, 2022
A Study of Small Volume Plasma Exchange in Guillain Barre Syndrome Patients Admitted in Gandhi Hospital
Introduction: Guillain Barre Syndrome (GBS) or Acute Polyradiculoneuritis is an acute, diffuse post-infective- disorder of the nervous system involving the spinal roots, the peripheral nerves and occasionally the cranial nerves....
Published by: IJHS Medical Association
Forecasting Stock Market Volume Price Using Sentimental and Technical Analysis
The stock market volume and price are active areas of research. Behind every dollar of investment, the customer will be hoping for profit in one or the other way. There is a positive correlation between investor sentiment and...
Published by: IGI Global Scientific Publishing
A Study of Small Volume Plasma Exchange in Guillain Barre Syndrome Patients Admitted in Gandhi Hospital
Introduction: Guillain Barre Syndrome (GBS) or Acute Polyradiculoneuritis is an acute, diffuse post-infective- disorder of the nervous system involving the spinal roots, the peripheral nerves and occasionally the cranial nerves....
Published by: IJHS Medical Association
Determinants of ERP Adoption, User Satisfaction, and User Engagement
Based on the theory of reasoned action (TRA) and the diffusion of innovation framework, this study examines the key determinants and outcomes of enterprise resource planning (ERP) adoption. The study specifically investigated...
Systems & Software Design Computer Science and Information Technology Systems and Software Engineering
Published by: IGI Global Scientific Publishing
BaalChIP
Ines de Santiago, Wei Liu, Ke Yuan, Martin O’Reilly, Chandra Sekhar Reddy Chilamakuri, Bruce A. J. Ponder, Kerstin B. Meyer, Florian Markowetz
May 05, 2017
Abstract
Allele-specific measurements of transcription factor binding from ChIP-seq data are key to dissecting the allelic effects of non-coding variants and their contribution to phenotypic diversity. However...
The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance.
Monika Mortensen, Elizabeth J Soilleux, Gordana Djordjevic, Rebecca Tripp, Michael Lutteropp, Elham Sadighi-Akha, Amanda J Stranks, Julie Glanville, Samantha Knight, Sten-Eirik W Jacobsen, Kamil R Kranc, Anna Katharina Simon
Dec 21, 2018
The role of autophagy, a lysosomal degradation pathway which prevents cellular damage, in the maintenance of adult mouse hematopoietic stem cells (HSCs) remains unknown. Although normal HSCs sustain life-long hematopoiesis...
Phospho-regulation of ATOH1 Is Required for Plasticity of Secretory Progenitors and Tissue Regeneration.
Goran Tomic, Edward Morrissey, Sarah Kozar, Shani Ben-Moshe, Alice Hoyle, Roberta Azzarelli, Richard Kemp, Chandra Sekhar Reddy Chilamakuri, Shalev Itzkovitz, Anna Philpott, Douglas J Winton
Nov 01, 2018
Conventional vs. Digital Dental Impression
Ivna Kekez, Gordana Karega, Marina Gadža, Benjamin Benzon, Ivana Mikić, Katarina Vukojevic, Danijela Govorko
Jan 01, 2022
Dental impressions are an important part of routine diagnostic and therapeutic dental procedures. Using conventional impression materials, the dentist captures intraoral details, and the dental technician uses impression for...
Published by: IGI Global Scientific Publishing
An exploratory qualitative study of the prevention of road traffic collisions and neurotrauma in India
Santhani M Selveindran, Gurusinghe D. N. Samarutilake, K. Madhu Narayana Rao, Jogi V. Pattisapu, Christine Hill, Angelos G. Kolias, Rajesh Pathi, Peter J. A. Hutchinson, M. V. Vijaya Sekhar
Mar 30, 2021
Abstract: Background: Despite current preventative strategies, road traffic collisions (RTCs) and resultant neurotrauma remain a major problem in India. This study seeks to explore local perspectives in the context within which...
An exploratory qualitative study of the prevention of road traffic collisions and neurotrauma in India
Santhani M Selveindran, Gurusinghe DN Samarutilake, K Madhu Narayana Rao, Jogi V Pattisapu, Christine Hill, Angelos G Kolias, Rajesh Pathi, Peter JA Hutchinson, MV Vijaya Sekhar
Jun 11, 2021
BACKGROUND: Despite current preventative strategies, road traffic collisions (RTCs) and resultant neurotrauma remain a major problem in India. This study seeks to explore local perspectives in the context within which RTCs take...
ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesinSTAG1 from WAPL.
Gordana Wutz, Rene Ladurner, Brian Glenn St Hilaire, Roman R Stocsits, Kota Nagasaka, Benoit Pignard, Adrian Sanborn, Wen Tang, Csilla Várnai, Miroslav P Ivanov, Stefan Schoenfelder, Petra van der Lelij, Xingfan Huang, Gerhard Dürnberger, Elisabeth Roitinger, Karl Mechtler, Iain Finley Davidson, Peter Fraser, Erez Lieberman-Aiden, Jan-Michael Peters
May 04, 2020
Eukaryotic genomes are folded into loops. It is thought that these are formed by cohesin complexes via extrusion, either until loop expansion is arrested by CTCF or until cohesin is removed from DNA by WAPL. Although WAPL limits...
CTCF TADs Cell Biology chromatin structure Chromosomes cohesin Gene Expression genome organization human loops Acetylation Acetyltransferases CCCTC-Binding Factor Carrier Proteins Cell Cycle Proteins Chromatin Chromosomal Proteins Non-Histone Computer Simulation G1 Phase Genome Human Humans Nuclear Proteins Protein Binding Proto-Oncogene Proteins
Probabilistic classification of anti-SARS-CoV-2 antibody responses improves seroprevalence estimates.
Xaquin Castro Dopico, Sandra Muschiol, Nastasiya F Grinberg, Soo Aleman, Daniel J Sheward, Leo Hanke, Marcus Ahl, Linnea Vikström, Mattias Forsell, Jonathan M Coquet, Gerald McInerney, Joakim Dillner, Gordana Bogdanovic, Ben Murrell, Jan Albert, Chris Wallace, Gunilla B Karlsson Hedestam
Mar 03, 2022
OBJECTIVES: Population-level measures of seropositivity are critical for understanding the epidemiology of an emerging pathogen, yet most antibody tests apply a strict cutoff for seropositivity that is not learnt in a...
A quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes.
Evangelia K Papachristou, Kamal Kishore, Andrew N Holding, Kate Harvey, Theodoros I Roumeliotis, Chandra Sekhar Reddy Chilamakuri, Soleilmane Omarjee, Kee Ming Chia, Alex Swarbrick, Elgene Lim, Florian Markowetz, Matthew Eldridge, Rasmus Siersbaek, Clive S D'Santos, Jason S Carroll
Sep 26, 2018
Understanding the dynamics of endogenous protein-protein interactions in complex networks is pivotal in deciphering disease mechanisms. To enable the in-depth analysis of protein interactions in chromatin-associated protein...
ARID1A influences HDAC1/BRD4 activity, intrinsic proliferative capacity and breast cancer treatment response.
Sankari Nagarajan, Shalini V Rao, Joseph Sutton, Danya Cheeseman, Shanade Dunn, Evangelia K Papachristou, Jose-Enrique Gonzalez Prada, Dominique-Laurent Couturier, Sanjeev Kumar, Kamal Kishore, Chandra Sekhar Reddy Chilamakuri, Silvia-Elena Glont, Emily Archer Goode, Cara Brodie, Naomi Guppy, Rachael Natrajan, Alejandra Bruna, Carlos Caldas, Alasdair Russell, Rasmus Siersbaek, Kosuke Yusa, Igor Chernukhin, Jason S Carroll
Nov 13, 2019
Acetylation Animals Breast Neoplasms Cell Cycle Proteins Cell Proliferation Clustered Regularly Interspaced Short Palindromic Repeats DNA-Binding Proteins Drug Resistance Neoplasm Estrogen Receptor alpha Female Gene Expression Regulation Neoplastic Hepatocyte Nuclear Factor 3-alpha Histone Deacetylase 1 Humans MCF-7 Cells Mice Inbred NOD Transcription Factors Xenograft Model Antitumor Assays
Low Contact Barrier in 2H/1T' MoTe2 In-Plane Heterostructure Synthesized by Chemical Vapor Deposition.
Xiang Zhang, Zehua Jin, Luqing Wang, Jordan A Hachtel, Eduardo Villarreal, Zixing Wang, Teresa Ha, Yusuke Nakanishi, Chandra Sekhar Tiwary, Jiawei Lai, Liangliang Dong, Jihui Yang, Robert Vajtai, Emilie Ringe, Juan Carlos Idrobo, Boris I Yakobson, Jun Lou, Vincent Gambin, Rachel Koltun, Pulickel M Ajayan
Apr 12, 2019
Metal-semiconductor contact has been a critical topic in the semiconductor industry because it influences device performance remarkably. Conventional metals have served as the major contact material in electronic and...
Results of a national UK physician reported survey of COVID-19 infection in patients with a myeloproliferative neoplasm.
Richard A Salisbury, Natalia Curto-Garcia, Jennifer O'Sullivan, Frederick Chen, Paolo Polzella, Anna L Godfrey, James Russell, Steven Knapper, John Willan, Rebecca Frewin, Shivani Joshi, Siamak Arami, Sarah Burns, Chun Huat Teh, Frances Wadelin, Jaymathi Dhanapal, Pratap Neelakantan, Dragana Milojkovic, Beth Psaila, Richard Szydlo, Sebastian Francis, Catherine Cargo, Manish Jain, Andrew McGregor, Louise Wallis, Andrew Duncombe, Hayder Hussein, Peter Dyer, Laura Munro, Lee Bond, Mary Frances McMullin, Tim CP Somervaille, Mamta Garg, Mallika Sekhar, Claire Harrison, Adam J Mead, Andrew J Innes
Jul 30, 2021
EN1 Is a Transcriptional Dependency in Triple-Negative Breast Cancer Associated with Brain Metastasis.
Guillermo Peluffo, Ashim Subedee, Nicholas W Harper, Natalie Kingston, Bojana Jovanović, Felipe Flores, Laura E Stevens, Francisco Beca, Anne Trinh, Chandra Sekhar Reddy Chilamakuri, Evangelia K Papachristou, Katherine Murphy, Ying Su, Andriy Marusyk, Clive S D'Santos, Oscar M Rueda, Andrew H Beck, Carlos Caldas, Jason S Carroll, Kornelia Polyak
Jul 09, 2019
To define transcriptional dependencies of triple-negative breast cancer (TNBC), we identified transcription factors highly and specifically expressed in primary TNBCs and tested their requirement for cell growth in a panel of...
Cross-linguistic patterns in the acquisition of quantifiers.
Napoleon Katsos, Chris Cummins, Maria-José Ezeizabarrena, Anna Gavarró, Jelena Kuvač Kraljević, Gordana Hrzica, Kleanthes K Grohmann, Athina Skordi, Kristine Jensen de López, Lone Sundahl, Angeliek van Hout, Bart Hollebrandse, Jessica Overweg, Myrthe Faber, Margreet van Koert, Nafsika Smith, Maigi Vija, Sirli Zupping, Sari Kunnari, Tiffany Morisseau, Manana Rusieshvili, Kazuko Yatsushiro, Anja Fengler, Spyridoula Varlokosta, Katerina Konstantzou, Shira Farby, Maria Teresa Guasti, Mirta Vernice, Reiko Okabe, Miwa Isobe, Peter Crosthwaite, Yoonjee Hong, Ingrida Balčiūnienė, Yanti Marina Ahmad Nizar, Helen Grech, Daniela Gatt, Win Nee Cheong, Arve Asbjørnsen, Janne von Koss Torkildsen, Ewa Haman, Aneta Miękisz, Natalia Gagarina, Julia Puzanova, Darinka Anđelković, Maja Savić, Smiljana Jošić, Daniela Slančová, Svetlana Kapalková, Tania Barberán, Duygu Özge, Saima Hassan, Cecilia Yuet Hung Chan, Tomoya Okubo, Heather van der Lely, Uli Sauerland, Ira Noveck
Jul 28, 2016
Genomic basis for RNA alterations in cancer.
PCAWG Transcriptome Core Group, Claudia Calabrese, Natalie R Davidson, Deniz Demircioğlu, Nuno A Fonseca, Yao He, André Kahles, Kjong-Van Lehmann, Fenglin Liu, Yuichi Shiraishi, Cameron M Soulette, Lara Urban, Liliana Greger, Siliang Li, Dongbing Liu, Marc D Perry, Qian Xiang, Fan Zhang, Junjun Zhang, Peter Bailey, Serap Erkek, Katherine A Hoadley, Yong Hou, Matthew R Huska, Helena Kilpinen, Jan O Korbel, Maximillian G Marin, Julia Markowski, Tannistha Nandi, Qiang Pan-Hammarström, Chandra Sekhar Pedamallu, Reiner Siebert, Stefan G Stark, Hong Su, Patrick Tan, Sebastian M Waszak, Christina Yung, Shida Zhu, Philip Awadalla, Chad J Creighton, Matthew Meyerson, BF Francis Ouellette, Kui Wu, Huanming Yang, PCAWG Transcriptome Working Group, Alvis Brazma, Angela N Brooks, Jonathan Göke, Gunnar Rätsch, Roland F Schwarz, Oliver Stegle, Zemin Zhang, PCAWG Consortium
Feb 04, 2021
Transcript alterations often result from somatic changes in cancer genomes1. Various forms of RNA alterations have been described in cancer, including overexpression2, altered splicing3 and gene fusions4; however, it is...
Determinants of cognitive performance and decline in 20 diverse ethno-regional groups
Darren M Lipnicki, Steve R Makkar, John D Crawford, Anbupalam Thalamuthu, Nicole A Kochan, Maria Fernanda Lima-Costa, Erico Castro-Costa, Cleusa Pinheiro Ferri, Carol Brayne, Blossom Stephan, Juan J Llibre-Rodriguez, Jorge J Llibre-Guerra, Adolfo J Valhuerdi-Cepero, Richard B Lipton, Mindy J Katz, Carol A Derby, Karen Ritchie, Marie-Laure Ancelin, Isabelle Carrière, Nikolaos Scarmeas, Mary Yannakoulia, Georgios M Hadjigeorgiou, Linda Lam, Wai-Chi Chan, Ada Fung, Antonio Guaita, Roberta Vaccaro, Annalisa Davin, Ki Woong Kim, Ji Won Han, Seung Wan Suh, Steffi G Riedel-Heller, Susanne Roehr, Alexander Pabst, Martin van Boxtel, Sebastian Köhler, Kay Deckers, Mary Ganguli, Erin P Jacobsen, Tiffany F Hughes, Kaarin J Anstey, Nicolas Cherbuin, Mary N Haan, Allison E Aiello, Kristina Dang, Shuzo Kumagai, Tao Chen, Kenji Narazaki, Tze Pin Ng, Qi Gao, Ma Shwe Zin Nyunt, Marcia Scazufca, Henry Brodaty, Katya Numbers, Julian N Trollor, Kenichi Meguro, Satoshi Yamaguchi, Hiroshi Ishii, Antonio Lobo, Raul Lopez-Anton, Javier Santabárbara, Yvonne Leung, Jessica W Lo, Gordana Popovic, Perminder S Sachdev, for Cohort Studies of Memory in an International Consortium (COSMIC)
Sep 03, 2019
BACKGROUND: With no effective treatments for cognitive decline or dementia, improving the evidence base for modifiable risk factors is a research priority. This study investigated associations between risk factors and late-life...
CCNE1 and survival of patients with tubo-ovarian high-grade serous carcinoma
Eun-Young Kang, Ashley Weir, Nicola S Meagher, Kyo Farrington, Gregg S Nelson, Prafull Ghatage, Cheng-Han Lee, Marjorie J Riggan, Adelyn Bolithon, Gordana Popovic, Betty Leung, Katrina Tang, Neil Lambie, Joshua Millstein, Jennifer Alsop, Michael S Anglesio, Beyhan Ataseven, Ellen Barlow, Matthias W Beckmann, Jessica Berger, Christiani Bisinotto, Hans Bösmüller, Jessica Boros, Alison H Brand, Angela Brooks-Wilson, Sara Y Brucker, Michael E Carney, Yovanni Casablanca, Alicia Cazorla-Jiménez, Paul A Cohen, Thomas P Conrads, Linda S Cook, Penny Coulson, Madeleine Courtney-Brooks, Daniel W Cramer, Philip Crowe, Julie M Cunningham, Cezary Cybulski, Kathleen M Darcy, Mona A El-Bahrawy, Esther Elishaev, Ramona Erber, Rhonda Farrell, Sian Fereday, Anna Fischer, María J García, Simon A Gayther, Aleksandra Gentry-Maharaj, C Blake Gilks, AOCS Group, Marcel Grube, Paul R Harnett, Shariska Petersen Harrington, Philipp Harter, Arndt Hartmann, Jonathan L Hecht, Sebastian Heikaus, Alexander Hein, Florian Heitz, Joy Hendley, Brenda Y Hernandez, Susanna Hernando Polo, Sabine Heublein, Akira Hirasawa, Estrid Høgdall, Claus K Høgdall, Hugo M Horlings, David G Huntsman, Tomasz Huzarski, Andrea Jewell, Mercedes Jimenez-Linan, Michael E Jones, Scott H Kaufmann, Catherine J Kennedy, Dineo Khabele, Felix KF Kommoss, Roy FPM Kruitwagen, Diether Lambrechts, Nhu D Le, Marcin Lener, Jenny Lester, Yee Leung, Anna Linder, Liselore Loverix, Jan Lubiński, Rashna Madan, G Larry Maxwell, Francesmary Modugno, Susan L Neuhausen, Alexander Olawaiye, Siel Olbrecht, Sandra Orsulic, José Palacios, Celeste Leigh Pearce, Malcolm C Pike, Carmel M Quinn, Ganendra Raj Mohan, Cristina Rodríguez-Antona, Matthias Ruebner, Andy Ryan, Stuart G Salfinger, Naoko Sasamoto, Joellen M Schildkraut, Minouk J Schoemaker, Mitul Shah, Raghwa Sharma, Yurii B Shvetsov, Naveena Singh, Gabe S Sonke, Linda Steele, Colin JR Stewart, Karin Sundfeldt, Anthony J Swerdlow, Aline Talhouk, Adeline Tan, Sarah E Taylor, Kathryn L Terry, Aleksandra Tołoczko, Nadia Traficante, Koen K van de Vijver, Maaike A van der Aa, Toon Van Gorp, Els Van Nieuwenhuysen, Lilian van-Wagensveld, Ignace Vergote, Robert A Vierkant, Chen Wang, Lynne R Wilkens, Stacey J Winham, Anna H Wu, Javier Benitez, Andrew Berchuck, Francisco J Candido Dos Reis, Anna DeFazio, Peter A Fasching, Ellen L Goode, Marc T Goodman, Jacek Gronwald, Beth Y Karlan, Stefan Kommoss, Usha Menon, Hans-Peter Sinn, Annette Staebler, James D Brenton, David D Bowtell, Paul DP Pharoah, Susan J Ramus, Martin Köbel
Jan 04, 2023
BACKGROUND: Cyclin E1 (CCNE1) is a potential predictive marker and therapeutic target in tubo-ovarian high-grade serous carcinoma (HGSC). Smaller studies have revealed unfavorable associations for CCNE1 amplification and CCNE1...
The transcription factor encyclopedia.
Dimas Yusuf, Stefanie L Butland, Magdalena I Swanson, Eugene Bolotin, Amy Ticoll, Warren A Cheung, Xiao Yu Cindy Zhang, Christopher TD Dickman, Debra L Fulton, Jonathan S Lim, Jake M Schnabl, Oscar HP Ramos, Mireille Vasseur-Cognet, Charles N de Leeuw, Elizabeth M Simpson, Gerhart U Ryffel, Eric W-F Lam, Ralf Kist, Miranda SC Wilson, Raquel Marco-Ferreres, Jan J Brosens, Leonardo L Beccari, Paola Bovolenta, Bérénice A Benayoun, Lara J Monteiro, Helma DC Schwenen, Lars Grontved, Elizabeth Wederell, Susanne Mandrup, Reiner A Veitia, Harini Chakravarthy, Pamela A Hoodless, M Michela Mancarelli, Bruce E Torbett, Alison H Banham, Sekhar P Reddy, Rebecca L Cullum, Michaela Liedtke, Mario P Tschan, Michelle Vaz, Angie Rizzino, Mariastella Zannini, Seth Frietze, Peggy J Farnham, Astrid Eijkelenboom, Philip J Brown, David Laperrière, Dominique Leprince, Tiziana de Cristofaro, Kelly L Prince, Marrit Putker, Luis del Peso, Gieri Camenisch, Roland H Wenger, Michal Mikula, Marieke Rozendaal, Sylvie Mader, Jerzy Ostrowski, Simon J Rhodes, Capucine Van Rechem, Gaylor Boulay, Sam WZ Olechnowicz, Mary B Breslin, Michael S Lan, Kyster K Nanan, Michael Wegner, Juan Hou, Rachel D Mullen, Stephanie C Colvin, Peter John Noy, Carol F Webb, Matthew E Witek, Scott Ferrell, Juliet M Daniel, Jason Park, Scott A Waldman, Daniel J Peet, Michael Taggart, Padma-Sheela Jayaraman, Julien J Karrich, Bianca Blom, Farhad Vesuna, Henriette O'Geen, Yunfu Sun, Richard M Gronostajski, Mark W Woodcroft, Margaret R Hough, Edwin Chen, G Nicholas Europe-Finner, Magdalena Karolczak-Bayatti, Jarrod Bailey, Oliver Hankinson, Venu Raman, David P LeBrun, Shyam Biswal, Christopher J Harvey, Jason P DeBruyne, John B Hogenesch, Robert F Hevner, Christophe Héligon, Xin M Luo, Marissa Cathleen Blank, Kathleen Joyce Millen, David S Sharlin, Douglas Forrest, Karin Dahlman-Wright, Chunyan Zhao, Yuriko Mishima, Satrajit Sinha, Rumela Chakrabarti, Elodie Portales-Casamar, Frances M Sladek, Philip H Bradley, Wyeth W Wasserman
Jul 09, 2012
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