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Results: 317
Paleovirological Analyses of Endogenous Retroviruses and Host Innate Immune Effectors
Daniel Blanco Melo
Jan 01, 0001
About 8 and 10 percent of the human and mouse genomes, respectively, are comprised of sequences of retroviral origin. Occasional infection of germ line can lead to integrated retroviral genomes being vertically inherited as host...
Published by: Rockefeller University
The temporal mutational and immune tumour microenvironment remodelling of HER2-negative primary breast cancers
Leticia De Mattos-Arruda, Javier Cortes, Juan Blanco-Heredia, Daniel G. Tiezzi, Guillermo Villacampa, Samuel Gonçalves-Ribeiro, Laia Paré, Carla Anjos Souza, Vanesa Ortega, Stephen-John Sammut, Pol Cusco, Roberta Fasani, Suet-Feung Chin, Jose Perez-Garcia, Rodrigo Dienstmann, Paolo Nuciforo, Patricia Villagrasa, Isabel T. Rubio, Aleix Prat, Carlos Caldas
Jun 07, 2021
Abstract: The biology of breast cancer response to neoadjuvant therapy is underrepresented in the literature and provides a window-of-opportunity to explore the genomic and microenvironment modulation of tumours exposed to...
The temporal mutational and immune tumour microenvironment remodelling of HER2-negative primary breast cancers.
Leticia De Mattos-Arruda, Javier Cortes, Juan Blanco-Heredia, Daniel G Tiezzi, Guillermo Villacampa, Samuel Gonçalves-Ribeiro, Laia Paré, Carla Anjos Souza, Vanesa Ortega, Stephen-John Sammut, Pol Cusco, Roberta Fasani, Suet-Feung Chin, Jose Perez-Garcia, Rodrigo Dienstmann, Paolo Nuciforo, Patricia Villagrasa, Isabel T Rubio, Aleix Prat, Carlos Caldas
Jul 26, 2021
The biology of breast cancer response to neoadjuvant therapy is underrepresented in the literature and provides a window-of-opportunity to explore the genomic and microenvironment modulation of tumours exposed to therapy. Here...
Mitochondrial DNA heteroplasmy in cardiac tissue from individuals with and without coronary artery disease
The cellular environment associated with coronary artery disease (CAD) can lead to mitochondrial DNA (mtDNA) damage. Mitochondrial variants in some copies of mtDNA (heteroplasmy) and mtDNA content are potential genetic...
Coronary Artery Disease Mitochondrial DNA heteroplasmy mitochondrial variation Mitochondria Cardiovascular Diseases Genetic Structures
Published by: Harrisburg University of Science and Technology
Technique of Classification, Organization, Creation, and Use of Collective Knowledge
During the teaching of a subject, engineering in this particular case, students acquire knowledge through different learning activities that are guided by the teaching staff. In this process, students work with the resources and...
Published by: IGI Global Scientific Publishing
The temporal mutational and immune tumour microenvironment remodelling of HER2-negative primary breast cancers.
Leticia De Mattos-Arruda, Javier Cortes, Juan Blanco-Heredia, Daniel G Tiezzi, Guillermo Villacampa, Samuel Gonçalves-Ribeiro, Laia Paré, Carla Anjos Souza, Vanesa Ortega, Stephen-John Sammut, Pol Cusco, Roberta Fasani, Suet-Feung Chin, Jose Perez-Garcia, Rodrigo Dienstmann, Paolo Nuciforo, Patricia Villagrasa, Isabel T Rubio, Aleix Prat, Carlos Caldas
Jul 28, 2021
The biology of breast cancer response to neoadjuvant therapy is underrepresented in the literature and provides a window-of-opportunity to explore the genomic and microenvironment modulation of tumours exposed to therapy. Here...
Published by: NPJ breast cancer
Rain Garden Maintenance Guide
Hannah Blanco
Jan 01, 0001
Gardens, while serving an aesthetic purpose, also have practical and ecological importance. They provide food and habitat for local pollinators and wildlife, and, in the case of the rain garden, perform the important task of...
Published by: Ursinus College
RápidoPGS
MOTIVATION: Polygenic scores (PGS) aim to genetically predict complex traits at an individual level. PGS are typically trained on genome-wide association summary statistics and require an independent test dataset to tune...
Anthracycline-Related Cardiotoxicity in Patients with Acute Myeloid Leukemia and Down Syndrome: A Literature Review
Pediatric patients with Down syndrome (DS) are at an increased risk of developing certain cancers. Specifically, patients with DS have a reported 10-20-fold increased risk of developing acute myeloid leukemia (AML)....
anthracycline Cardiotoxicity Pediatric AML Leukemia Down Syndrome Doxorubicin Chemicals and Drugs Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Published by: Harrisburg University of Science and Technology
Presumed killers? Vultures, stakeholders, misperceptions, and fake news
Sergio A. Lambertucci, Antoni Margalida, Karina L. Speziale, Arjun Amar, Fernando Ballejo, Keith L. Bildstein, Guillermo Blanco, André J. Botha, Christopher G.R. Bowden, Ainara Cortés‐Avizanda, Olivier Duriez, Rhys E. Green, Fernando Hiraldo, Darcy Ogada, Pablo Plaza, José A. Sánchez‐Zapata, Andrea Santangeli, Nuria Selva, Orr Spiegel, José A. Donázar
May 05, 2021
Abstract: Vultures and condors are among the most threatened avian species in the world due to the impacts of human activities. Negative perceptions can contribute to these threats as some vulture species have been historically...
Analysis of Heteroplasmic Variants in the Cardiac Mitochondrial Genome of Individuals with Down Syndrome
Individuals with Down syndrome (DS, trisomy 21) exhibit a pro-oxidative cellular environment as well as mitochondrial dysfunction. Increased oxidative stress may damage the mitochondrial DNA (mtDNA). The coexistence of mtDNA...
Down syndrome; trisomy 21; heteroplasmy; cardiac; mitochondrial variants; massively parallel sequencing Congenital, Hereditary, and Neonatal Diseases and Abnormalities Genetics and Genomics
Published by: Harrisburg University of Science and Technology
Measuring Green Practices in Sport
Environmental sustainability has often been associated with increased organizational profitability, efficiency, and competitiveness. A related example is green practices which have become a central component of many...
Green Practices Scale development Sports sustainability /dk/atira/pure/subjectarea/asjc/1700/1701 name=Computer Science (miscellaneous) /dk/atira/pure/subjectarea/asjc/3300/3305 name=Geography, Planning and Development /dk/atira/pure/subjectarea/asjc/2100/2105 name=Renewable Energy, Sustainability and the Environment /dk/atira/pure/subjectarea/asjc/2300/2301 name=Environmental Science (miscellaneous) /dk/atira/pure/subjectarea/asjc/2100/2102 name=Energy Engineering and Power Technology /dk/atira/pure/subjectarea/asjc/1700/1708 name=Hardware and Architecture /dk/atira/pure/subjectarea/asjc/1700/1705 name=Computer Networks and Communications /dk/atira/pure/subjectarea/asjc/2300/2308 name=Management, Monitoring, Policy and Law /dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energy name=SDG 7 - Affordable and Clean Energy
A Brain for Language and the Language of the Brain
Guillermo A Cecchi
Jan 01, 0001
This thesis consists of three sections. In the first one, we overview the basic concepts and results of computation theory, the relationship with formal language theory, and present an introduction to the possible applications...
Published by: Rockefeller University
Cancer Surveillance Guideline for individuals with PTEN hamartoma tumour syndrome
Chrystelle Colas, Sjaak Pouwels, Nicoline Hoogerbrugge, Tanya Bisseling, Virginie Bubien, Frederic Caux, Nathalie Chabbert-Buffet, Sophie Da Mota Gomes, Martin Gotthardt, Marleen Kets, Katherine L. Lachlan, Thera P. Links, Michel Longy, Ritse Mann, Leo Schultze Kool, Robert K. Semple, Ian Stock, Marc Tischkowitz, Janet Vos, Marjolijn Ligtenberg, Rianne Oostenbrink, Rolf Sijmons, Gareth Evans, Emma Woodward, Eamonn Maher, Rosalie E. Ferner, Stefan Aretz, Isabel Spier, Verena Steinke-Lange, Elke Holinski-Feder, Evelin Schröck, Thierry Frebourg, Claude Houdayer, Pierre Wolkenstein, Vincent Bours, Eric Legius, Bruce Poppe, Kathleen Claes, Robin de Putter, Ignacio Blanco Guillermo, Gabriel Capella, Joan Brunet Vidal, Conxi Lázaro, Judith Balmaña, Hector Salvador Hernandez, Carla Oliveira, Manuel Teixeira, Svetlana Bajalica-Lagercrantz, Emma Tham, Jan Lubinski, Karolina Ertmanska, Bela Melegh, Mateja Krajc, Ana Blatnik, Sirkku Peltonen, Marja Hietala
Feb 09, 2021
Abstract: PTEN hamartoma tumour syndrome is a diverse multi-system disorder predisposing to the development of hamartomatous growths, increasing risk of breast, thyroid, renal cancer, and possibly increasing risk of endometrial...
Open access dataset of task-free hemodynamic activity in 4-month-old infants during sleep using fNIRS.
Spontaneous, task-free, hemodynamic activity of the brain provides useful information about its functional organization, as it can describe how different brain regions communicate to each other. Neuroimaging studies measuring...
Quantitative Experimental Embryology
Published by: MDPI
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