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Mkk4 is a negative regulator of the transforming growth factor beta 1 signaling associated with atrial remodeling and arrhythmogenesis with age.
Laura Davies, Jiawei Jin, Weijin Shen, Hoyee Tsui, Ying Shi, Yanwen Wang, Yanmin Zhang, Guoliang Hao, JingJing Wu, Si Chen, James A Fraser, Nianguo Dong, Vincent Christoffels, Ursula Ravens, Christopher L-H Huang, Henggui Zhang, Elizabeth J Cartwright, Xin Wang, Ming Lei
Oct 19, 2020
BACKGROUND: Atrial fibrillation (AF), often associated with structural, fibrotic change in cardiac tissues involving regulatory signaling mediators, becomes increasingly common with age. In the present study, we explored the...
aging Atrial fibrillation cardiac remodeling Age Factors Aged Angiotensin II Animals Atrial fibrillation Atrial Remodeling Case-Control Studies Cells Cultured Computer Simulation Down-Regulation Female Fibrosis Heart Rate Humans MAP Kinase Kinase 4 Male Mice Mice Knockout Myocytes Cardiac Rats Rats Sprague-Dawley Signal Transduction Transfection Transforming Growth Factor beta1
Water Resources Assessment and Management for Nuclear Power Plants in China
To deal with global warming and energy shortage, nuclear power plants are constructed or planning to be constructed in China presently. The operation of a nuclear power plant consumes a great amount of water and discharges a lot...
Phase structure and properties of sodium bismuth titanate lead-free piezoelectric ceramics
The lead-free sodium bismuth titanate (BNT) system has been extensively investigated in the past decade due to its multi-functional electro-active properties. Here, we present a comprehensive review that encompasses the...
A Middle Pleistocene Denisovan molar from the Annamite Chain of northern Laos.
Fabrice Demeter, Clément Zanolli, Kira E Westaway, Renaud Joannes-Boyau, Philippe Duringer, Mike W Morley, Frido Welker, Patrick L Rüther, Matthew M Skinner, Hugh McColl, Charleen Gaunitz, Lasse Vinner, Tyler E Dunn, Jesper V Olsen, Martin Sikora, Jean-Luc Ponche, Eric Suzzoni, Sébastien Frangeul, Quentin Boesch, Pierre-Olivier Antoine, Lei Pan, Song Xing, Jian-Xin Zhao, Richard M Bailey, Souliphane Boualaphane, Phonephanh Sichanthongtip, Daovee Sihanam, Elise Patole-Edoumba, Françoise Aubaile, Françoise Crozier, Nicolas Bourgon, Alexandra Zachwieja, Thonglith Luangkhoth, Viengkeo Souksavatdy, Thongsa Sayavongkhamdy, Enrico Cappellini, Anne-Marie Bacon, Jean-Jacques Hublin, Eske Willerslev, Laura Shackelford
Jun 29, 2022
The Pleistocene presence of the genus Homo in continental Southeast Asia is primarily evidenced by a sparse stone tool record and rare human remains. Here we report a Middle Pleistocene hominin specimen from Laos, with the...
Water Resources Assessment and Management for Nuclear Power Plants in China
To deal with global warming and energy shortage, nuclear power plants are constructed or planning to be constructed in China presently. The operation of a nuclear power plant consumes a great amount of water and discharges a lot...
A Middle Pleistocene Denisovan molar from the Annamite Chain of northern Laos.
Fabrice Demeter, Clément Zanolli, Kira E Westaway, Renaud Joannes-Boyau, Philippe Duringer, Mike W Morley, Frido Welker, Patrick L Rüther, Matthew M Skinner, Hugh McColl, Charleen Gaunitz, Lasse Vinner, Tyler E Dunn, Jesper V Olsen, Martin Sikora, Jean-Luc Ponche, Eric Suzzoni, Sébastien Frangeul, Quentin Boesch, Pierre-Olivier Antoine, Lei Pan, Song Xing, Jian-Xin Zhao, Richard M Bailey, Souliphane Boualaphane, Phonephanh Sichanthongtip, Daovee Sihanam, Elise Patole-Edoumba, Françoise Aubaile, Françoise Crozier, Nicolas Bourgon, Alexandra Zachwieja, Thonglith Luangkhoth, Viengkeo Souksavatdy, Thongsa Sayavongkhamdy, Enrico Cappellini, Anne-Marie Bacon, Jean-Jacques Hublin, Eske Willerslev, Laura Shackelford
May 18, 2022
The Pleistocene presence of the genus Homo in continental Southeast Asia is primarily evidenced by a sparse stone tool record and rare human remains. Here we report a Middle Pleistocene hominin specimen from Laos, with the...
Phase structure and properties of sodium bismuth titanate lead-free piezoelectric ceramics
The lead-free sodium bismuth titanate (BNT) system has been extensively investigated in the past decade due to its multi-functional electro-active properties. Here, we present a comprehensive review that encompasses the...
Intrusion Detection Using Normalized Mutual Information Feature Selection and Parallel Quantum Genetic Algorithm
This paper presents a detection algorithm using normalized mutual information feature selection and cooperative evolution of multiple operators based on adaptive parallel quantum genetic algorithm (NMIFS MOP- AQGA). The proposed...
Published by: IGI Global Scientific Publishing
A Study of Knowledge Discovery and Pattern Recognition Based on Large-Scale Sentiment Data in Online Education for College Students
With the development of the internet, online education platforms have become the main means of acquiring knowledge for people. To improve the efficiency of user analysis, this paper proposes a framework for user sentiment...
Published by: IGI Global Scientific Publishing
Five new genes are important for common polysaccharide antigen biosynthesis in <em>Pseudomonas aeruginosa</em>
Common polysaccharide antigen (CPA) is a conserved cell surface polysaccharide produced by Pseudomonas aeruginosa. It contains a rhamnan homopolymer and is one of the two forms of O polysaccharide attached to P. aeruginosa...
Out of Asia
Shigella are ranked among the most prevalent aetiologies of diarrhoeal disease worldwide, disproportionately affecting young children in developing countries and high-risk communities in developed settings. Antimicrobial...
Exploration of Intelligent Teaching Means of Ideological and Political Education in Colleges and Universities Under the Background of “Mass Entrepreneurship”
Hao Yang
Jan 01, 2024
The concept of “great ideological and political education” requires comprehensive ideological education to better achieve the educational goals of “innovation and entrepreneurship.” This article analyzes and explores the...
Published by: IGI Global Scientific Publishing
Research on the Capacity Allocation and Planning Model of a Flexible Direct Current Transmission System Based on Swarm Intelligence Optimization Algorithm
Weihan Hao
Jan 01, 2024
Based on the contradiction between the increasing power demand and the low capacity of the traditional direct current (DC) transmission system, this study innovatively combines the swarm intelligence optimization algorithm with...
Published by: IGI Global Scientific Publishing
Downgoing Plate-Buoyancy Driven Retreat of North Sulawesi Trench
Solid Earth ATMOSPHERIC COMPOSITION AND STRUCTURE Air/sea constituent fluxes Volcanic effects BIOGEOSCIENCES Climate dynamics modeling COMPUTATIONAL GEOPHYSICS Numerical Solutions cryosphere avalanches Mass balance geochemistry Subduction zone processes GEODESY AND GRAVITY Earth's interior: composition and state earth's interior: dynamics Ocean monitoring with geodetic techniques Ocean/Earth/atmosphere/hydrosphere/cryosphere interactions Global change from geodesy GEOMAGNETISM AND PALEOMAGNETISM Core processes global change abrupt/rapid climate change climate variability Earth system modeling Impacts of global change Land/atmosphere interactions Oceans Regional climate change Sea level change Water cycles hydrology Climate impacts Hydrological cycles and budgets Informatics MARINE GEOLOGY AND GEOPHYSICS Gravity and isostasy ATMOSPHERIC PROCESSES Climate change and variability Climatology general circulation Ocean/atmosphere interactions Regional modeling Theoretical modeling MINERALOGY AND PETROLOGY OCEANOGRAPHY: GENERAL Climate and interannual variability numerical modeling NATURAL HAZARDS Atmospheric Geological Oceanic Physical modeling Climate impact risk Disaster risk analysis and assessment OCEANOGRAPHY: PHYSICAL Air/sea interactions Decadal ocean variability Ocean influence of Earth rotation Sea level: variations and mean Surface waves and tides Tsunamis and storm surges Paleoceanography POLICY SCIENCES Benefit‐cost analysis RADIO SCIENCE Radio oceanography seismology core mantle Earthquake ground motions and engineering seismology Volcano seismology TECTONOPHYSICS Continental margins: convergent Dynamics of lithosphere and mantle: general Continental margins: divergent Volcanology Volcano/climate interactions atmospheric effects volcano monitoring Effusive volcanism Mud volcanism Explosive volcanism Volcanic hazards and risks Research Letter
Efficient Task Offloading for Mobile Edge Computing in Vehicular Networks
In vechcular networks, a promising approach to enhance vehicle task processing capabilities involves using a combination of roadside base stations or vehicles, there are two challenges when integrating the two offloading modeth...
Published by: IGI Global Scientific Publishing
The Impact of E-Commerce on Urban Green Innovation Development
Green innovation development is essential to achieve “carbon neutrality and carbon peaking” and drive sustainable urban growth, which greatly influences the global green economy. This paper probes into the influence of...
Published by: IGI Global Scientific Publishing
An Intrusion Detection System Based on Normalized Mutual Information Antibodies Feature Selection and Adaptive Quantum Artificial Immune System
The intrusion detection system (IDS) has lower speed, less adaptability and lower detection accuracy especially for small samples sets. This paper presents a detection model based on normalized mutual antibodies information...
Published by: IGI Global Scientific Publishing
Evaluation Model of Modern Network Teaching Quality Based on Artificial Intelligence E-Learning
Modern e-learning system is a representative service form in innovative service industry. This paper designs a personalized service domain system, optimizes various parameters and can be applied to different education quality...
Published by: IGI Global Scientific Publishing
Analysis of Extraction Algorithm for Visual Navigation of Farm Robots Based on Dark Primary Colors
In order to quickly extract the visual navigation line of farmland robot, an extraction algorithm for dark primary agricultural machinery is proposed. The application of dark primary color principle in new farmland is made...
Published by: IGI Global Scientific Publishing
Selective Chemical Vapor Deposition Growth of WS2/MoS2 Vertical and Lateral Heterostructures on Gold Foils.
Zixuan Wang, Wenshuo Xu, Benxuan Li, Qiaoyan Hao, Di Wu, Dianyu Qi, Haibo Gan, Junpeng Xie, Guo Hong, Wenjing Zhang
May 18, 2022
Vertical and lateral heterostructures consisting of atomically layered two-dimensional (2D) materials exhibit intriguing properties, such as efficient charge/energy transfer, high photoresponsivity, and enhanced photocatalytic...
An Equivalent Model of Gas Networks for Dynamic Analysis of Gas-Electricity Systems
The increasing coupling between natural gas and electricity systems by gas-fired generation units brings new challenges to system analysis, such as pressure variations due to consumption perturbations of generation units. The...
A multi-stage approach for empty container repositioning under coordination among linear carriers
This paper studies the empty container repositioning (ECR) problem considering the exchange of slots and empty containers among liner shipping companies. It is common for an individual shipping company to seek an optimal...
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