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HD 56414 b
Abstract
We report the discovery in TESS data and validation of HD 56414 b (a.k.a. TOI-1228 b), a Neptune-size (R
...
S Giacalone, CD Dressing, AG Muñoz, MJ Hooton, KG Stassun, SN Quinn, G Zhou, C Ziegler, R Vanderspek, DW Latham, S Seager, JN Winn, JM Jenkins, C Briceño, CX Huang, DR Rodriguez, A Shporer, AW Mann, D Watanabe, B Wohler
Aug 12, 2022
Exploring the predictors of financial impairment in Huntington's disease using the Enroll-HD dataset.
OBJECTIVES: Huntington's disease (HD) is a neurodegenerative disease in which cognitive and behavioural symptoms impair the performance of instrumental activities of daily living, including the handling of finances. We sought to...
Independent Validation of the Temperate Super-Earth HD 79211 b using HARPS-N
Abstract
We present high-precision radial velocities (RVs) from the HARPS-N spectrograph for HD 79210 and HD 79211, two M0V members of a gravitationally bound binary system. We...
Victoria DiTomasso, Chantanelle Nava, Mercedes López-Morales, Allyson Bieryla, Ryan Cloutier, Luca Malavolta, Annelies Mortier, Lars A Buchhave, Keivan G Stassun, Alessandro Sozzetti, Aldo Stefano Bonomo, David Charbonneau, Andrew Collier Cameron, Rosario Cosentino, Mario Damasso, Xavier Dumusque, AF Martínez Fiorenzano, Adriano Ghedina, Avet Harutyunyan, RD Haywood, David Latham, Emilio Molinari, Francesco A Pepe, Matteo Pinamonti, Ennio Poretti, Ken Rice, Dimitar Sasselov, Manu Stalport, Stéphane Udry, Christopher Watson, Thomas G Wilson
Jan 06, 2023
Antidopaminergic treatment is associated with reduced chorea and irritability but impaired cognition in Huntington’s disease (Enroll-HD)
Objectives: Alterations in dopamine neurotransmission underlie some of the clinical features of Huntington’s disease (HD) and as such are a target for therapeutic intervention, especially for the treatment of chorea and some...
Published by: BMJ Publishing Group
Rhyming and Undeciding in Wordsworth and Norman Nicholson
S McDowell
Mar 10, 2017
Wordsworth's poem ‘Yarrow Unvisited’ suggests that it is better not to go somewhere than to go and risk being disappointed. Responding to this idea in the poem ‘Askam Unvisited’, the twentieth-century Cumbrian poet Norman...
Antidopaminergic treatment is associated with reduced chorea and irritability but impaired cognition in Huntington’s disease (Enroll-HD)
Objectives: Alterations in dopamine neurotransmission underlie some of the clinical features of Huntington’s disease (HD) and as such are a target for therapeutic intervention, especially for the treatment of chorea and some...
Published by: BMJ Publishing Group
ALMA Observations of the HD 110058 Debris Disk
Abstract
We present Atacama Large Millimeter/submillimeter Array (ALMA) observations of the young, gas-rich debris disk around HD 110058 at 0.″3–0.″6 resolution. The disk is...
AS Hales, S Marino, PD Sheehan, S Ulloa, S Pérez, L Matrà, Q Kral, M Wyatt, W Dent, J Carpenter
Dec 08, 2022
Huntington's disease patients display progressive deficits in hippocampal-dependent cognition during a task of spatial memory.
Kate L Harris, Matthew Armstrong, Rachel Swain, Sharon Erzinclioglu, Tilak Das, Neil Burgess, Roger A Barker, Sarah L Mason
Aug 22, 2019
BACKGROUND: Cognitive disturbances occur early in Huntington's disease (HD) and place a significant burden on the lives of patients and family members. Whilst these impairments are typically attributed to deterioration of the...
Abnormally abrupt transitions from sleep-to-wake in Huntington's disease sheep (Ovis aries) are revealed by automated analysis of sleep/wake transition dynamics.
Sleep disturbance is a common and disruptive symptom of neurodegenerative diseases such as Alzheimer's and Huntington's disease (HD). In HD patients, sleep fragmentation appears at an early stage of disease, although features of...
Published by: PLOS ONE
Linking Atmospheric Chemistry of the Hot Jupiter HD 209458b to Its Formation Location through Infrared Transmission and Emission Spectra
Abstract
The elemental ratios of carbon, nitrogen, and oxygen in the atmospheres of hot Jupiters may hold clues to their formation locations in the protostellar disk. In this work...
S Dash, L Majumdar, K Willacy, SM Tsai, N Turner, PB Rimmer, MS Gudipati, W Lyra, A Bhardwaj
Jun 10, 2022
Regulatory responses to medical machine learning.
Companies and healthcare providers are developing and implementing new applications of medical artificial intelligence, including the artificial intelligence sub-type of medical machine learning (MML). MML is based on the...
Published by: Journal of law and the biosciences
NICHOLSON LECTURE
The Rockefeller University
Jan 01, 0001
Julien R. Zierath, Ph.D.
Molecular Mechanism for the Health-promoting Effects of Exercise: Why Muscle Matters!
Published by: The Rockefeller University
NICHOLSON LECTURE
The Rockefeller University
Jan 01, 0001
Thomas Perlamann, Ph.D.: Transcriptional Control of Dopamine Neuron Specification and Maintenance
Published by: The Rockefeller University
Regulatory responses to medical machine learning.
Companies and healthcare providers are developing and implementing new applications of medical artificial intelligence, including the artificial intelligence sub-type of medical machine learning (MML). MML is based on the...
The Role of Intrusive Imagery in Hoarding Disorder
Despite the incidence of trauma in the histories of people with Hoarding Disorder (HD), reexperiencing symptoms, namely intrusive images, have not been investigated in the condition. To address this, 27 individuals who met...
Comparison of the health-related quality of life of end stage kidney disease patients on hemodialysis and non-hemodialysis management in Uganda.
Peace Bagasha, Elizabeth Namukwaya, Mhoira Leng, Robert Kalyesubula, Edrisa Mutebi, Ronald Naitala, Elly Katabira, Mila Petrova
Apr 02, 2021
BACKGROUND: Health-related quality of life is recognized as a key outcome in chronic disease management, including kidney disease. With no national healthcare coverage for hemodialysis, Ugandan patients struggle to pay for their...
Problems with Social Cognition and Decision-Making in Huntington's Disease
Huntington's disease starts slowly and progresses over a 15-20 year period. Motor changes begin subtly, often going unnoticed by patients although they are typically visible to those close to them. At this point, it is the early...
Groups satisfying a strong complement property
Let G=NH be a finite group where N is normal in G and H is a complement of N in G. For a given generating sequence (h1,…,hd) of H we say that (N,(h1,…,hd)) satisfies the strong complement property, if 〈h1 x1,…,hd xd〉 is a...
The roles of intolerance of uncertainty, anxiety sensitivity and distress tolerance in hoarding disorder compared with OCD and healthy controls
Shemariah R. Hillman, Claire L. Lomax, Nadeen Khaleel, Theresa R. Smith, James D. Gregory
Jul 31, 2022
Background: It is suggested that the different psychological vulnerability factors of intolerance of uncertainty (IU), anxiety sensitivity (AS) and distress tolerance (DT) may be in important in hoarding disorder (HD)....
NICHOLSON LECTURE
The Rockefeller University
Jan 01, 0001
Camilla Sjögren, Ph.D.
Connecting Chromosome Replication and Segregation: DNA Topology and SMC Complexes
Published by: The Rockefeller University
Abnormally abrupt transitions from sleep-to-wake in Huntington's disease sheep (Ovis aries) are revealed by automated analysis of sleep/wake transition dynamics.
Sleep disturbance is a common and disruptive symptom of neurodegenerative diseases such as Alzheimer's and Huntington's disease (HD). In HD patients, sleep fragmentation appears at an early stage of disease, although features of...
A genetic modifier suggests that endurance exercise exacerbates Huntington's disease.
Silvia Corrochano, Gonzalo Blanco, Debbie Williams, Jessica Wettstein, Michelle Simon, Saumya Kumar, Lee Moir, Thomas Agnew, Michelle Stewart, Allison Landman, Vassilios N Kotiadis, Michael R Duchen, Henning Wackerhage, David C Rubinsztein, Steve DM Brown, Abraham Acevedo-Arozena
Sep 27, 2018
Polyglutamine expansions in the huntingtin gene cause Huntington's disease (HD). Huntingtin is ubiquitously expressed, leading to pathological alterations also in peripheral organs. Variations in the length of the polyglutamine...
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