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Results: 35
Investigating upper urinary tract urothelial carcinomas
Harveer S Dev, Stephanie Poo, James Armitage, Oliver Wiseman, Nimish Shah, Samih Al-Hayek
Apr 19, 2016
Cytology Endoscopic biopsy Tumour grade Upper urinary tract urothelial carcinoma Ureteroscopy Aged Aged 80 and over Biopsy Carcinoma Transitional Cell Cytodiagnosis Female Humans Kidney Neoplasms Kidney Pelvis Male Middle Aged Retrospective Studies Sensitivity and Specificity Time Factors Tomography X-Ray Computed Ureteral Neoplasms Ureteroscopy Urine
mCSM–NA
Binding Sites DNA DNA-Binding Proteins Humans Internet Machine Learning Models Molecular Models Statistical Mutation Missense Protein Binding Protein Conformation alpha-Helical Protein Conformation beta-Strand Protein Interaction Domains and Motifs Protein Stability RNA-Binding Proteins Reverse Genetics Software Thermodynamics
Role of Hydrophobicity at the N-Terminal Region of Aβ42 in Secondary Nucleation.
The self-assembly of the amyloid β 42 (Aβ42) peptide is linked to Alzheimer's disease, and oligomeric intermediates are linked to neuronal cell death during the pathology of the disease. These oligomers are produced prolifically...
Nonequilibrium Carrier Transport in Quantum Dot Heterostructures.
Understanding carrier dynamics and transport in quantum dot based heterostructures is crucial for unlocking their full potential for optoelectronic applications. Here we report the direct visualization of carrier propagation in...
Artificial Bee Colony Optimized Deep Neural Network Model for Handling Imbalanced Stroke Data
The healthcare domain gets wide attention among the research community due to incremental data growth, advanced diagnostic tools, medical imaging processes, and many more. Enormous healthcare data is generated through diagnostic...
Published by: IGI Global Scientific Publishing
Telemedicine Adoption in India
COVID-19 pandemic mandates the transformation of the traditional healthcare delivery model from facility-based to virtual care worldwide. The use of technology in delivering health care has always been debated and faces...
Published by: IGI Global Scientific Publishing
A Kinetic Map of the Influence of Biomimetic Lipid Model Membranes on Aβ42 Aggregation.
Kevin N Baumann, Greta Šneiderienė, Michele Sanguanini, Matthias Schneider, Oded Rimon, Alicia González Díaz, Heather Greer, Dev Thacker, Sara Linse, Tuomas PJ Knowles, Michele Vendruscolo
Jan 19, 2023
Functional interactions between polypyrimidine tract binding protein and PRI peptide ligand containing proteins.
MB Coelho, DB Ascher, C Gooding, E Lang, H Maude, D Turner, M Llorian, DEV Pires, J Attig, CWJ Smith
Jun 10, 2016
Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells.
Harveer Dev, Ting-Wei Will Chiang, Chloe Lescale, Inge de Krijger, Alistair G Martin, Domenic Pilger, Julia Coates, Matylda Sczaniecka-Clift, Wenming Wei, Matthias Ostermaier, Mareike Herzog, Jonathan Lam, Abigail Shea, Mukerrem Demir, Qian Wu, Fengtang Yang, Beiyuan Fu, Zhongwu Lai, Gabriel Balmus, Rimma Belotserkovskaya, Violeta Serra, Mark J O'Connor, Alejandra Bruna, Petra Beli, Luca Pellegrini, Carlos Caldas, Ludovic Deriano, Jacqueline JL Jacobs, Yaron Galanty, Stephen P Jackson
Sep 29, 2018
BRCA1 deficiencies cause breast, ovarian, prostate and other cancers, and render tumours hypersensitive to poly(ADP-ribose) polymerase (PARP) inhibitors. To understand the resistance mechanisms, we conducted whole-genome...
Animals BRCA1 Protein Bone Neoplasms Breast Neoplasms Cell Cycle Proteins Cell Line Tumor cisplatin DNA Breaks Double-Stranded DNA End-Joining Repair DNA-Binding Proteins Dose-Response Relationship Drug Drug Resistance Neoplasm Female HEK293 Cells Humans Mad2 Proteins Mice Multiprotein Complexes Osteosarcoma Ovarian Neoplasms Poly(ADP-ribose) Polymerase Inhibitors Proteins Recombinational DNA Repair Telomere-Binding Proteins Tumor Suppressor p53-Binding Protein 1 Xenograft Model Antitumor Assays
Correction: SoxF factors induce Notch1 expression via direct transcriptional regulation during early arterial development. Development doi
Ivy Kim-Ni Chiang, Martin Fritzsche, Cathy Pichol-Thievend, Alice Neal, Kelly Holmes, Anne Lagendijk, Jeroen Overman, Donatella D'Angelo, Alice Omini, Dorien Hermkens, Emmanuelle Lesieur, Nicolas Fossat, Tania Radziewic, Ke Liu, Indrika Ratnayaka, Monica Corada, George Bou-Gharios, Patrick PL Tam, Jason Carroll, Elisabetta Dejana, Stefan Schulte-Merker, Benjamin M Hogan, Monica Beltrame, Sarah De Val, Mathias Francois
Jul 16, 2019
A Kinetic Map of the Influence of Biomimetic Lipid Model Membranes on Aβ42 Aggregation.
Kevin N Baumann, Greta Šneiderienė, Michele Sanguanini, Matthias Schneider, Oded Rimon, Alicia González Díaz, Heather Greer, Dev Thacker, Sara Linse, Tuomas PJ Knowles, Michele Vendruscolo
Jan 27, 2023
Tetrafluoroborate‐Induced Reduction in Defect Density in Hybrid Perovskites through Halide Management
Satyawan Nagane, Stuart Macpherson, Michael A. Hope, Dominik J. Kubicki, Weiwei Li, Sachin Dev Verma, Jordi Ferrer Orri, Yu‐Hsien Chiang, Judith L. MacManus‐Driscoll, Clare P. Grey, Samuel D. Stranks
Jul 07, 2021
RESEARCH ARTICLE RESEARCH ARTICLES charge‐carrier recombination DEFECTS perovskite solar cells Photoluminescence Surface treatment tetrafluoroborate
Published by: Advanced Materials
Being in a loop
Chromatin architecture has a significant impact on gene expression. Evidence in the last two decades support RNA as an important component of chromatin structure [Genes Dev. (2005) 19, 1635–1655; PLoS ONE (2007) 2, e1182; Nat....
HuDA_COVID Human Disposition Analysis During COVID-19 Using Machine Learning
Coronavirus has greatly impacted various aspects of human life, including human psychology & human disposition. In this paper, we attempted to analyze the impact of the COVID-19 pandemic on human health. We propose Human...
Published by: IGI Global Scientific Publishing
Being in a loop
Chromatin architecture has a significant impact on gene expression. Evidence in the last two decades support RNA as an important component of chromatin structure [Genes Dev. (2005) 19, 1635–1655; PLoS ONE (2007) 2, e1182; Nat....
Extracting quantitative dielectric properties from pump-probe spectroscopy.
Large-scale analysis of microRNA expression, epi-transcriptomic features and biogenesis.
MicroRNAs are important genetic regulators in both animals and plants. They have a range of functions spanning development, differentiation, growth, metabolism and disease. The advent of next-generation sequencing technologies...
A homozygous mutation in the TUB gene associated with retinal dystrophy and obesity.
Arundhati Dev Borman, Laura R Pearce, Donna S Mackay, Kerstin Nagel-Wolfrum, Alice E Davidson, Robert Henderson, Sumedha Garg, Naushin H Waseem, Andrew R Webster, Vincent Plagnol, Uwe Wolfrum, I Sadaf Farooqi, Anthony T Moore
Mar 17, 2015
Extracting quantitative dielectric properties from pump-probe spectroscopy.
Arjun Ashoka, Ronnie R Tamming, Aswathy V Girija, Hope Bretscher, Sachin Dev Verma, Shang-Da Yang, Chih-Hsuan Lu, Justin M Hodgkiss, David Ritchie, Chong Chen, Charles G Smith, Christoph Schnedermann, Michael B Price, Kai Chen, Akshay Rao
Apr 19, 2022
Optical pump-probe spectroscopy is a powerful tool for the study of non-equilibrium electronic dynamics and finds wide applications across a range of fields, from physics and chemistry to material science and biology. However, a...
Cyclical fate restriction
Robert N. Kelsh, Karen Camargo Sosa, Saeed Farjami, Vsevolod Makeev, Jonathan H.P. Dawes, Andrea Rocco
Nov 30, 2021
Neural crest cells are crucial in development, not least because of their remarkable multipotency. Early findings stimulated two hypotheses for how fate specification and commitment from fully multipotent neural crest cells...
Clarification of mural cell coverage of vascular endothelial cells by live imaging of zebrafish
Mural cells (MCs) consisting of vascular smooth muscle cells and pericytes cover the endothelial cells (ECs) to regulate vascular stability and homeostasis. Here, we clarified the mechanism how MCs develop and cover ECs by...
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