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Olfactory bulb hypoplasia in Prokr2 null mice stems from defective neuronal progenitor migration and differentiation.
New neurons are added on a daily basis to the olfactory bulb (OB) of a mammal, and this phenomenon exists throughout its lifetime. These new cells are born in the subventricular zone and migrate to the OB via the rostral...
Animals Animals Newborn Bromodeoxyuridine Cell Count Cell Differentiation Cell Movement Doublecortin Domain Proteins Female Gastrointestinal Hormones Homozygote Humans Lactation Mice Mice Inbred C57BL Mice Knockout Microtubule-Associated Proteins Neural Cell Adhesion Molecule L1 Neurons Neuropeptides Olfactory Bulb Receptors G-Protein-Coupled Receptors Peptide Recombinant Proteins Sialic Acids Spheroids Cellular Stem Cells Tyrosine 3-Monooxygenase
A resource of vectors and ES cells for targeted deletion of microRNAs in mice.
The 21-23 nucleotide, single-stranded RNAs classified as microRNAs (miRNA) perform fundamental roles in diverse cellular and developmental processes. In contrast to the situation for protein-coding genes, no public resource of...
Ectodomains of the LDL receptor-related proteins LRP1b and LRP4 have anchorage independent functions in vivo.
Martin F Dietrich, Louise van der Weyden, Haydn M Prosser, Allan Bradley, Joachim Herz, David J Adams
Oct 14, 2020
BACKGROUND: The low-density lipoprotein (LDL) receptor gene family is a highly conserved group of membrane receptors with diverse functions in developmental processes, lipoprotein trafficking, and cell signaling. The low-density...
Agouti C57BL/6N embryonic stem cells for mouse genetic resources.
Stephen J Pettitt, Qi Liang, Xin Y Rairdan, Jennifer L Moran, Haydn M Prosser, David R Beier, Kent C Lloyd, Allan Bradley, William C Skarnes
Oct 22, 2020
We report the characterization of a highly germline competent C57BL/6N mouse embryonic stem cell line, JM8. To simplify breeding schemes, the dominant agouti coat color gene was restored in JM8 cells by targeted repair of the...
Agouti Signaling Protein Animals Base Sequence Cell Line Crosses Genetic DNA Primers Embryonic Stem Cells Female Gene Targeting Genetic Techniques Germ-Line Mutation Hair Color Male Mice Mice Inbred C57BL Mice Knockout Mice Mutant Strains Mice Transgenic Polymorphism Single Nucleotide Pregnancy Transplantation Chimera
Mesenchyme-derived IGF2 is a major paracrine regulator of pancreatic growth and function
Constanze M. Hammerle, Ionel Sandovici, Gemma V. Brierley, Nicola M. Smith, Warren E. Zimmer, Ilona Zvetkova, Haydn M. Prosser, Yoichi Sekita, Brian Y. H. Lam, Marcella Ma, Wendy N. Cooper, Antonio Vidal-Puig, Susan E. Ozanne, Gema Medina-Gómez, Miguel Constância
Nov 20, 2020
The genetic mechanisms that determine the size of the adult pancreas are poorly understood. Imprinted genes, which are expressed in a parent-of-origin-specific manner, are known to have important roles in development, growth and...
MiR-211 is essential for adult cone photoreceptor maintenance and visual function.
Sara Barbato, Elena Marrocco, Daniela Intartaglia, Mariateresa Pizzo, Sabrina Asteriti, Federica Naso, Danila Falanga, Rajeshwari S Bhat, Nicola Meola, Annamaria Carissimo, Marianthi Karali, Haydn M Prosser, Lorenzo Cangiano, Enrico Maria Surace, Sandro Banfi, Ivan Conte
Apr 20, 2018
MicroRNAs (miRNAs) are key post-transcriptional regulators of gene expression that play an important role in the control of fundamental biological processes in both physiological and pathological conditions. Their function in...
Interview with Johann M. McCrackin
Johann M. McCrackin
Jan 01, 0001
Interview with Johann M. McCrackin, 1984 South Carolina Mother of the Year.
Published by: Winthrop University
Prelamin A causes progeria through cell-extrinsic mechanisms and prevents cancer invasion.
Jorge de la Rosa, José MP Freije, Rubén Cabanillas, Fernando G Osorio, Mario F Fraga, M Soledad Fernández-García, Roland Rad, Víctor Fanjul, Alejandro P Ugalde, Qi Liang, Haydn M Prosser, Allan Bradley, Juan Cadiñanos, Carlos López-Otín
Oct 14, 2020
Defining the relationship between ageing and cancer is a crucial but challenging task. Mice deficient in Zmpste24, a metalloproteinase mutated in human progeria and involved in nuclear prelamin A maturation, recapitulate...
Polymorphism in M(H2PO2)3 (M = V, Al, Ga) compounds with the perovskite-related ReO3 structure.
Hayden A Evans, Zeyu Deng, Ines E Collings, Yue Wu, Jessica L Andrews, Kartik Pilar, Joshua M Tuffnell, Guang Wu, John Wang, Siân E Dutton, Paul D Bristowe, Ram Seshadri, Anthony K Cheetham
Feb 18, 2019
Trivalent metal hypophosphites with the general formula M(H2PO2)3 (M = V, Al, Ga) adopt the ReO3 structure, with each compound displaying two structural polymorphs. High-pressure synchrotron X-ray studies reveal a...
Mesenchyme-derived IGF2 is a major paracrine regulator of pancreatic growth and function.
Constanze M Hammerle, Ionel Sandovici, Gemma V Brierley, Nicola M Smith, Warren E Zimmer, Ilona Zvetkova, Haydn M Prosser, Yoichi Sekita, Brian YH Lam, Marcella Ma, Wendy N Cooper, Antonio Vidal-Puig, Susan E Ozanne, Gema Medina-Gómez, Miguel Constância
Aug 24, 2020
Thomas M. Rivers, 1934
The Rockefeller University
Jan 01, 0001
Dr. Thomas M. Rivers. Filterable Viruses with Particular Reference to Psittacosis
Lecture delivered April 19th, 1934
Posted with permission
Published by: The Williams & Wilkins Company
Investigating Students' Intention to Use M-Learning
Mohammed Almulla
Jan 01, 2024
Mobile learning (M-learning) has become a crucial tool for both students and educators. The unified theory of acceptance and use of technology (UTAUT), the technology acceptance model (TAM), and outside factors were all included...
Published by: IGI Global Scientific Publishing
Digital M&A and Firm Innovation
This study empirically examines how digital M&A affects firm innovation using data from Chinese listed companies from 2006 to 2019. The results show that digital M&A promotes firm innovation, and our findings also suggest that...
Published by: IGI Global Scientific Publishing
JEFFREY M. FRIEDMAN
The Rockefeller University
Jan 01, 0001
congratulations to Professor Jeffrey M. Friedman, recipient of the 2010 Albert Lasker Basic Medical Research Award
Published by: The Rockefeller University
High voltage sulphate cathodes Li<sub>2</sub>M(SO<sub>4</sub>)<sub>2</sub> (M = Fe, Mn, Co)
The search for high voltage cathodes for lithium-ion batteries has led to recent interest in the monoclinic Li2Fe(SO4)2 material which has a voltage of 3.83 V vs. lithium, the highest recorded for a fluorine-free iron-based...
Frederick M. Allen, 1916
The Rockefeller University
Jan 01, 0001
Frederick M. Allen, M.D. The Role of Fat in Diabetes.
Delivered November 4th, 1916
Published by: J.B. Lippincott Company
High voltage sulphate cathodes Li<sub>2</sub>M(SO<sub>4</sub>)<sub>2</sub> (M = Fe, Mn, Co)
The search for high voltage cathodes for lithium-ion batteries has led to recent interest in the monoclinic Li2Fe(SO4)2 material which has a voltage of 3.83 V vs. lithium, the highest recorded for a fluorine-free iron-based...
Going veggie
We conceptualize the journey to ethical veganism in the stages of the transtheoretical model of change, from precontemplation through contemplation, preparation, action, and maintenance. At each stage, we explore the...
IN MEMORY OF RALPH M. STEINMAN
The Rockefeller University
Jan 01, 0001
A Scientific Symposium in Memory of Ralph M. Steinman
See Steinman, Ralph M.
Published by: The Rockefeller University
Unexpected Migratory Insertion Reactions of M(alkyl)<sub>2</sub> (M = Zn, Cd) and Diamidocarbenes
The electrophilic character of free diamidocarbenes (DACs) allows them to activate inert bonds in small molecules, such as NH3 and P4. Herein, we report that metal coordinated DACs also exhibit...
Going veggie
We conceptualize the journey to ethical veganism in the stages of the transtheoretical model of change, from precontemplation through contemplation, preparation, action, and maintenance. At each stage, we explore the...
Factors Affecting Continuance Intention of M-Government
Thamer Alshammari
Jan 01, 2023
Mobile government (m-government) can potentially provide substantial benefits. Nonetheless, the low level of use has prevented realizing the potential benefits of m-government. As a result, researchers have studied the factors...
Published by: IGI Global Scientific Publishing
Wendell M. Stanley, 1938
The Rockefeller University
Jan 01, 0001
Dr. Wendell M. Stanley. The Isolation and Properties of Tobacco Mosaic and Other Virus Proteins
Lecture delivered March, 17th, 1938
Posted with permission
Published by: The William & Wilkins Company
Exploring environmental supply chain innovation in m&a
Organisations are challenged with executing innovation for sustainable development within the context of their operations and value networks—networks which are increasingly fuelled by mergers and acquisitions (M&As)...
The evolution of the dust temperatures of galaxies in the SFR-<i>M</i> plane up to z sim 2
B. Magnelli, D. Lutz, A. Saintonge, S. Berta, P. Santini, M. Symeonidis, B. Altieri, P. Andreani, H. Aussel, M. Béthermin, J. Bock, A. Bongiovanni, J. Cepa, A. Cimatti, A. Conley, E. Daddi, D. Elbaz, N. M. Förster Schreiber, R. Genzel, R. J. Ivison, E. Le Floc'h, G. Magdis, R. Maiolino, R. Nordon, S. J. Oliver, M. Page, A. Pérez García, A. Poglitsch, P. Popesso, F. Pozzi, L. Riguccini, G. Rodighiero, D. Rosario, I. Roseboom, M. Sanchez-Portal, D. Scott, E. Sturm, L. J. Tacconi, I. Valtchanov, L. Wang, S. Wuyts
Jan 01, 2014
We study the evolution of the dust temperature of galaxies in the SFR− M∗ plane up to z ~ 2 using far-infrared and submillimetre observations from the Herschel Space Observatory taken as part of the PACS Evolutionary Probe (PEP)...
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