Search
Results: 375
Synthesis, Suzuki Couplings, and Small-molecule Inhibitors
Patrick Gray
Jan 01, 0001
The goal of this research project was to design and synthesize small-molecule inhibitors using reductive amination, Suzuki coupling, and the addition of protecting groups.
small molecules INHIBITORS reductive amination Suzuki coupling Organic chemistry Physical Sciences and Mathematics
Published by: Ursinus College
Copper(i)-catalyzed sulfonylative Suzuki-Miyaura cross-coupling.
Using a simple copper(i) catalyst has allowed a high yielding sulfonylative-Suzuki-Miyaura cross-coupling reaction to be developed. The process provides a single step route to diaryl sulfones from the direct combination of aryl...
Synthesis of a novel polycyclic ring scaffold with antimitotic properties via a selective domino Heck-Suzuki reaction.
Esther Alza, Luca Laraia, Brett M Ibbeson, Súil Collins, Warren RJD Galloway, Jamie E Stokes, Ashok R Venkitaraman, David R Spring
Jan 23, 2018
The synthesis of a previously undescribed sp3-rich 6-5-5-6 tetracyclic ring scaffold using a palladium catalysed domino Heck-Suzuki reaction is reported. This reaction is high-yielding, selective for the domino process over the...
Estimating Operating States of Numerical Control Milling Machines Using Wi-Fi Sensing and Channel State Information
This study investigates whether wi-fi sensing, through channel state information (CSI), can estimate the operating state and the material machined by a numerical control (NC) milling machine without contact sensors. The research...
Published by: IGI Global Scientific Publishing
RIKEN MetaDatabase
Recently, the number and heterogeneity of life science datasets published on the Web have increased significantly. However, biomedical scientists face numerous serious difficulties finding, using and publishing useful databases....
Published by: IGI Global Scientific Publishing
Robust and reusable supported palladium catalysts for cross-coupling reactions in flow
Two novel polymer encapsulated silica supported palladium catalysts have been prepared and shown to be highly active, robust and recyclable catalysts for Heck and Suzuki–Miyaura cross coupling reactions under continuous flow...
Post-synthetic modification of zinc metal-organic frameworks through palladium-catalysed carbon-carbon bond formation
Andrew D. Burrows, Laura C. Fisher, Timothy J. Mays, Sean P. Rigby, Sharon E. Ashbrook, Daniel M. Dawson
Sep 01, 2015
Post-synthetic Suzuki coupling reactions have been undertaken on the halide-functionalised metal-organic frameworks (MOFs) [Zn4O(bdc-Br)3] (bdc-Br = 2-bromo-1,4-benzenedicarboxylate, IRMOF-2) and...
The Ursinus Weekly, March 3, 1924
Negative debaters prove strongest Many Ursinus men are wage earners Pastor professes contact with deity Hiroshi Ono, ex-'22 writes from Japan Varsity defeats PMC, 36-32 Dreams of YW come true in new room W.S.G.A....
Ursinus College Collegeville Pennsylvania newspaper A. Edwin Keigwin Basketball student government debate team YMCA YWCA cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Robust and reusable supported palladium catalysts for cross-coupling reactions in flow
Two novel polymer encapsulated silica supported palladium catalysts have been prepared and shown to be highly active, robust and recyclable catalysts for Heck and Suzuki–Miyaura cross coupling reactions under continuous flow...
Direct core functionalisation of naphthalenediimides by iridium catalysed C–H borylation
Catherine L. Lyall, Camilla C. Shotton, Monserrat Pérez-salvia, Dan Pantos, Simon E. Lewis
Nov 18, 2014
We report the first boron-substituted naphthalenediimides (NDIs), prepared by iridium catalysed C–H activation. When the NDI substrates bear N-benzyl substituents, the naphthyl NDI core is borylated in preference, suggestive of...
Brightness masking is modulated by disparity structure.
Binocular depth perception Brightness estimation Filling-in Visual masking Adult Analysis of Variance Contrast Sensitivity Female Form Perception Humans Lighting Male Optical Illusions Perceptual Masking Photic Stimulation Psychophysics Sensory Thresholds Vision Disparity Vision Binocular Vision Monocular Young Adult
Field surveys of September 2018 landslide-generated waves in the Apporo dam reservoir, Japan
We report and analyze a case study of landslide-generated waves that occurred in the Apporo dam reservoir (Hokkaido, Japan) culminating from the rare incident of hazard combination from the September 2018 Typhoon Jebi and...
fMRI Analysis-by-Synthesis Reveals a Dorsal Hierarchy That Extracts Surface Slant.
3-D vision binocular disparity fMRI slant Analysis of Variance Brain Cues Depth Perception discrimination Psychological Female Humans Image Processing Computer-Assisted Magnetic Resonance Imaging Male Orientation Oxygen Photic Stimulation Psychophysics Regression Analysis Reproducibility of Results Students Universities Vision Disparity Visual Pathways
Post-synthetic modification of zinc metal-organic frameworks through palladium-catalysed carbon-carbon bond formation
Andrew D. Burrows, Laura C. Fisher, Timothy J. Mays, Sean P. Rigby, Sharon E. Ashbrook, Daniel M. Dawson
Sep 01, 2015
Post-synthetic Suzuki coupling reactions have been undertaken on the halide-functionalised metal-organic frameworks (MOFs) [Zn4O(bdc-Br)3] (bdc-Br = 2-bromo-1,4-benzenedicarboxylate, IRMOF-2) and...
7 tesla FMRI reveals systematic functional organization for binocular disparity in dorsal visual cortex.
Nuno R Goncalves, Hiroshi Ban, Rosa M Sánchez-Panchuelo, Susan T Francis, Denis Schluppeck, Andrew E Welchman
Mar 11, 2015
Direct core functionalisation of naphthalenediimides by iridium catalysed C–H borylation
Catherine L. Lyall, Camilla C. Shotton, Monserrat Pérez-salvia, Dan Pantos, Simon E. Lewis
Nov 18, 2014
We report the first boron-substituted naphthalenediimides (NDIs), prepared by iridium catalysed C–H activation. When the NDI substrates bear N-benzyl substituents, the naphthyl NDI core is borylated in preference, suggestive of...
Field surveys of September 2018 landslide-generated waves in the Apporo dam reservoir, Japan
We report and analyze a case study of landslide-generated waves that occurred in the Apporo dam reservoir (Hokkaido, Japan) culminating from the rare incident of hazard combination from the September 2018 Typhoon Jebi and...
Simulations and spectra of water in CO matrices.
Rafael Escribano, Emilio Artacho, Akira Kouchi, Tetusya Hama, Yuki Kimura, Hiroshi Hidaka, Naoki Watanabe
Aug 17, 2017
Models for the inclusion of water molecules in carbon monoxide matrices are developed using density functional theory applied to amorphous solid systems. The models cover a large range of systems for smaller or larger CO...
ALS mutations in FUS cause neuronal dysfunction and death in Caenorhabditis elegans by a dominant gain-of-function mechanism.
Tetsuro Murakami, Seung-Pil Yang, Lin Xie, Taizo Kawano, Donald Fu, Asuka Mukai, Christopher Bohm, Fusheng Chen, Janice Robertson, Hiroshi Suzuki, Gian Gaetano Tartaglia, Michele Vendruscolo, Gabriele S Kaminski Schierle, Fiona TS Chan, Aileen Moloney, Damian Crowther, Clemens F Kaminski, Mei Zhen, Peter St George-Hyslop
Feb 12, 2020
It is unclear whether mutations in fused in sarcoma (FUS) cause familial amyotrophic lateral sclerosis via a loss-of-function effect due to titrating FUS from the nucleus or a gain-of-function effect from cytoplasmic...
Perceptual integration for qualitatively different 3-D cues in the human brain.
The visual system's flexibility in estimating depth is remarkable: We readily perceive 3-D structure under diverse conditions from the seemingly random dots of a "magic eye" stereogram to the aesthetically beautiful, but...
Integration of texture and disparity cues to surface slant in dorsal visual cortex.
Reliable estimation of three-dimensional (3D) surface orientation is critical for recognizing and interacting with complex 3D objects in our environment. Human observers maximize the reliability of their estimates of surface...
Areal differences in depth cue integration between monkey and human.
Electrophysiological evidence suggested primarily the involvement of the middle temporal (MT) area in depth cue integration in macaques, as opposed to human imaging data pinpointing area V3B/kinetic occipital area (V3B/KO). To...
Regulation of forward and backward locomotion through intersegmental feedback circuits in Drosophila larvae.
Hiroshi Kohsaka, Maarten F Zwart, Akira Fushiki, Richard D Fetter, James W Truman, Albert Cardona, Akinao Nose
Aug 21, 2019
Animal locomotion requires spatiotemporally coordinated contraction of muscles throughout the body. Here, we investigate how contractions of antagonistic groups of muscles are intersegmentally coordinated during bidirectional...
Asymmetric parental genome engineering by Cas9 during mouse meiotic exit
Mammalian genomes can be edited by injecting pronuclear embryos with Cas9 cRNA and guide RNA (gRNA) but it is unknown whether editing can also occur during the onset of embryonic development, prior to pronuclear embryogenesis....
|
|< |
< |
1 |