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Results: 5703
Polycystin-1 inhibits eIF2α phosphorylation and cell apoptosis through a PKR-eIF2α pathway.
Yan Tang, Zuocheng Wang, JungWoo Yang, Wang Zheng, Di Chen, Guanqing Wu, Richard Sandford, Jingfeng Tang, Xing-Zhen Chen
Jan 17, 2018
Autosomal dominant polycystic kidney disease (ADPKD) is caused by mutations in PKD1 or PKD2 which encodes polycystin-1 (PC1) and polycystin-2, respectively. PC1 was previously shown to slow cell proliferation and inhibit...
Vortex coupling in trailing vortex-wing interactions
The interaction of trailing vortices of an upstream wing with rigid and flexible downstream wings has been investigated experimentally in a wind tunnel, using particle image velocimetry, hot-wire, force and deformation...
Vortex coupling in trailing vortex-wing interactions
The interaction of trailing vortices of an upstream wing with rigid and flexible downstream wings has been investigated experimentally in a wind tunnel, using particle image velocimetry, hot-wire, force and deformation...
Dual-function cellulose composites for fluorescence detection and removal of fluoride
Meng Li, Zhijiang Liu, Hui Chen Wang, Adam C. Sedgwick, Jordan E. Gardiner, Steven D. Bull, Hui Ning Xiao, Tony D. James
Feb 01, 2018
A biodegradable and robust fluorogenic cellulose material for simultaneous fluoride recognition and adsorption at environmentally significant levels is presented. The fluorescent modified cellulose (FMC) containing a boronic...
Dual-function cellulose composites for fluorescence detection and removal of fluoride
Meng Li, Zhijiang Liu, Hui Chen Wang, Adam C. Sedgwick, Jordan E. Gardiner, Steven D. Bull, Hui Ning Xiao, Tony D. James
Feb 01, 2018
A biodegradable and robust fluorogenic cellulose material for simultaneous fluoride recognition and adsorption at environmentally significant levels is presented. The fluorescent modified cellulose (FMC) containing a boronic...
Clinical and biomarker trajectories in sporadic Alzheimer's disease
Hui-Fu Wang, Xue-Ning Shen, Jie-Qiong Li, John Suckling, Chen-Chen Tan, Yan-Jiang Wang, Lei Feng, Can Zhang, Lan Tan, Qiang Dong, Jacques Touchon, Serge Gauthier, Jin-Tai Yu, Alzheimer's Disease Neuroimaging Initiative
Sep 01, 2020
Introduction: Amyloid beta (Aβ) deposition was identified to precede tau pathology and neurodegeneration in familial Alzheimer's disease (AD). But the divergence between sporadic and familial AD limits the extension of these...
CAMKs support development of acute myeloid leukemia.
Xunlei Kang, Changhao Cui, Chen Wang, Guojin Wu, Heyu Chen, Zhigang Lu, Xiaoli Chen, Li Wang, Jie Huang, Huimin Geng, Meng Zhao, Zhengshan Chen, Markus Müschen, Huan-You Wang, Cheng Cheng Zhang
Oct 03, 2018
BACKGROUND: We recently identified the human leukocyte immunoglobulin-like receptor B2 (LILRB2) and its mouse ortholog-paired Ig-like receptor (PirB) as receptors for several angiopoietin-like proteins (Angptls). We also...
acute myeloid leukemia CAMK CREB LILRB2 Leukemic stem cell PirB Animals Calcium-Calmodulin-Dependent Protein Kinases Carcinogenesis Cell Line Tumor Disease Models Animal Disease Progression Humans Leukemia Myeloid Acute Mice Inbred C57BL Neoplastic Stem Cells Receptors Immunologic Signal Transduction
Frequency and longitudinal clinical outcomes of Alzheimer's AT(N) biomarker profiles
Jin-Tai Yu, Jie-Qiong Li, John Suckling, Lei Feng, An Pan, Yan-Jiang Wang, Bo Song, Shan-Liang Zhu, De-Hu Li, Hui-Fu Wang, Chen-Chen Tan, Qiang Dong, Lan Tan, Vincent Mok, Paul S Aisen, Michael M Weiner, Alzheimer's Disease Neuroimaging Initiative
Aug 21, 2019
INTRODUCTION: We aimed to estimate the frequency of each AT(N) (β-amyloid deposition [A], pathologic tau [T], and neurodegeneration [N]) profile in different clinical diagnosis groups and to describe the longitudinal change in...
Research on Removing Image Noise and Distortion in Machine Dial Recognition
This study aims to address the issues of image noise and distortion in machine dial recognition via initial denoising. A wavelet local threshold denoising method that combines high-frequency wavelet coefficients with wavelet...
Published by: IGI Global Scientific Publishing
Localization Algorithm Based on a Spring Particle Model (LASPM) for Large-Scale Unmanned Aerial Vehicle Swarm (UAVs)
A new localization algorithm based on large scale unmanned aerial vehicle swarm (UAVs) is proposed in the paper. The localization algorithm is based on a spring particle model (LASPM). It simulates the dynamic process of...
Published by: IGI Global Scientific Publishing
Longitudinal trajectories of Alzheimer's ATN biomarkers in elderly persons without dementia.
Meng-Shan Tan, Xi Ji, Jie-Qiong Li, Wei Xu, Hui-Fu Wang, Chen-Chen Tan, Qiang Dong, Chuan-Tao Zuo, Lan Tan, John Suckling, Jin-Tai Yu, Alzheimer’s Disease Neuroimaging Initiative
May 22, 2020
BACKGROUND: Models of Alzheimer's disease (AD) pathophysiology posit that amyloidosis [A] precedes and accelerates tau pathology [T] that leads to neurodegeneration [N]. Besides this A-T-N sequence, other biomarker sequences are...
Masks for COVID-19.
Wei Deng, Yajun Sun, Xiaoxue Yao, Karpagam Subramanian, Chen Ling, Hongbo Wang, Shauhrat S Chopra, Ben Bin Xu, Jie-Xin Wang, Jian-Feng Chen, Dan Wang, Honeyfer Amancio, Stevin Pramana, Ruquan Ye, Steven Wang
Dec 15, 2021
Sustainable solutions on fabricating and using a face mask to block the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread during this coronavirus pandemic of 2019 (COVID-19) are required as society is directed...
Cross-sectional and plan-view cathodoluminescence of GaN partially coalesced above a nanocolumn array
The optical properties of GaN layers coalesced above an array of nanocolumns have important consequences for advanced optoelectronic devices. GaN nanocolumns coalesced using a nanoscale epitaxial overgrowth technique have been...
Unveiling the additive-assisted oriented growth of perovskite crystallite for high performance light-emitting diodes.
Lin Zhu, Hui Cao, Chen Xue, Hao Zhang, Minchao Qin, Jie Wang, Kaichuan Wen, Zewu Fu, Tao Jiang, Lei Xu, Ya Zhang, Yu Cao, Cailing Tu, Ju Zhang, Dawei Liu, Guangbin Zhang, Decheng Kong, Ning Fan, Gongqiang Li, Chang Yi, Qiming Peng, Jin Chang, Xinhui Lu, Nana Wang, Wei Huang, Jianpu Wang
Oct 26, 2021
Solution-processed metal halide perovskites have been recognized as one of the most promising semiconductors, with applications in light-emitting diodes (LEDs), solar cells and lasers. Various additives have been widely used in...
Data and videos for ultrafast synchrotron X-ray imaging studies of metal solidification under ultrasound.
Bing Wang, Dongyue Tan, Tung Lik Lee, Jia Chuan Khong, Feng Wang, Dmitry Eskin, Thomas Connolley, Kamel Fezzaa, Jiawei Mi
Oct 10, 2018
The data presented in this article are related to the paper entitled 'Ultrafast synchrotron X-ray imaging studies of microstructure fragmentation in solidification under ultrasound' [Wang et al., Acta Mater. 144 (2018) 505-515]....
Towards a Text-World Approach to Translation and Its Pedagogical Implications
Although it is widely acknowledged that translation is a cognitive process, there is scarcely any study establishing connections between the text and mental representations and giving a systematic and comprehensive explanation...
Published by: IGI Global Scientific Publishing
Optical Coherence Tomography Angiography Reveals Distinct Retinal Structural and Microvascular Abnormalities in Cerebrovascular Disease
Xiayin Zhang, Hui Xiao, Chunxin Liu, Sanxin Liu, Lanqin Zhao, Ruixin Wang, Jinghui Wang, Ting Wang, Yi Zhu, Chuan Chen, Xiaohang Wu, Duoru Lin, Wei Qiu, Patrick Yu-Wai-Man, Zhengqi Lu, Haotian Lin
Oct 16, 2020
Cerebrovascular disease (CeVD) is one of the leading global causes of death and severe disability. To date, retinal microangiopathy has become a reflection of cerebral microangiopathy, mirroring the vascular pathological...
Optical Coherence Tomography Angiography Reveals Distinct Retinal Structural and Microvascular Abnormalities in Cerebrovascular Disease.
Xiayin Zhang, Hui Xiao, Chunxin Liu, Sanxin Liu, Lanqin Zhao, Ruixin Wang, Jinghui Wang, Ting Wang, Yi Zhu, Chuan Chen, Xiaohang Wu, Duoru Lin, Wei Qiu, Patrick Yu-Wai-Man, Zhengqi Lu, Haotian Lin
Dec 07, 2020
Cerebrovascular disease (CeVD) is one of the leading global causes of death and severe disability. To date, retinal microangiopathy has become a reflection of cerebral microangiopathy, mirroring the vascular pathological...
Localized management of non-indigenous animal domesticates in Northwestern China during the Bronze Age.
Petra Vaiglova, Rachel EB Reid, Emma Lightfoot, Suzanne E Pilaar Birch, Hui Wang, Guoke Chen, Shuicheng Li, Martin Jones, Xinyi Liu
Aug 26, 2021
The movements of ancient crop and animal domesticates across prehistoric Eurasia are well-documented in the archaeological record. What is less well understood are the precise mechanisms that farmers and herders employed to...
Attention Pyramid Networks for Object Detection With Semantic Information Fusion
Pyramid context information fusion has limitations in distinguishing background and important semantic information. The attention mechanism solves the limitations, but the detection effect for small target detection and occluded...
Published by: IGI Global Scientific Publishing
Cross-sectional and plan-view cathodoluminescence of GaN partially coalesced above a nanocolumn array
The optical properties of GaN layers coalesced above an array of nanocolumns have important consequences for advanced optoelectronic devices. GaN nanocolumns coalesced using a nanoscale epitaxial overgrowth technique have been...
Evaluation of Reactivity of Monoclonal Antibodies Against Omp25 of Brucella spp.
Xin Yang, Zuoping He, Guoxia Zhang, Jinhui Lu, Hui Zhang, Hui Ren, Yanjun Tian, Heng Yang, Chuangfu Chen, Linhai Li, Yongshui Fu, Jean-Pierre Allain, Chengyao Li, Wenjing Wang
May 05, 2020
Brucellosis is a serious zoonosis occurring mainly in developing countries, and its diagnosis is largely dependent on serologic detection and bacterial culture. In this study, we developed the murine monoclonal antibodies (mAbs)...
DNMTs Play an Important Role in Maintaining the Pluripotency of Leukemia Inhibitory Factor-Dependent Embryonic Stem Cells.
Baojiang Wu, Yunxia Li, Bojiang Li, Baojing Zhang, Yanqiu Wang, Lin Li, Junpeng Gao, Yuting Fu, Shudong Li, Chen Chen, M Azim Surani, Fuchou Tang, Xihe Li, Siqin Bao
Apr 16, 2021
Naive pluripotency can be maintained in medium with two inhibitors plus leukemia inhibitory factor (2i/LIF) supplementation, which primarily affects canonical WNT, FGF/ERK, and JAK/STAT3 signaling. However, whether one of these...
DNA Methylation DNMTs DIFFERENTIATION Embryonic Stem Cells epigenetic Genomic Imprinting Leukemia Inhibitory Factor MOUSE Pluripotency self-renew Animals Cell Culture Techniques Cell Differentiation Cell Self Renewal Cells Cultured Culture Media DNA (Cytosine-5-)-Methyltransferases DNA Methylation DNA Methyltransferase 3A Gene Expression Regulation Developmental Gene Knockout Techniques Genomic Imprinting Germ Layers Janus Kinases Leukemia Inhibitory Factor Mice Mice Inbred C57BL Mice Transgenic Mouse embryonic stem cells STAT3 Transcription Factor Signal Transduction Transcriptome
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