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Corrigendum
Scientific Reports 6: Article number: 31205; published online: 05 August 2016; updated: 26 September 2016. The original version of this Article contained an error in the spelling of the author Immaculada Montanuy which...
Betty Lau, Emma Poole, Benjamin Krishna, Immaculada Montanuy, Mark R Wills, Eain Murphy, John Sinclair
Nov 29, 2017
Neutron Radiation Dose Measurements in a Scanning Proton Therapy Room
Vladimir Mares, Jad Farah, Marijke De Saint-Hubert, Szymon Domański, Carles Domingo, Martin Dommert, Magdalena Kłodowska, Katarzyna Krzempek, Michał Kuć, Immaculada Martínez-Rovira, Edyta Michaś, Natalia Mojżeszek, Łukasz Murawski, Ondrej Ploc, Maite Romero-Expósito, Marco Tisi, François Trompier, Olivier Van Hoey, Laurent Van Ryckeghem, Marek Wielunski, Roger M Harrison, Liliana Stolarczyk, Pawel Olko
Jul 28, 2022
PURPOSE: This study aims to characterize the neutron radiation field inside a scanning proton therapy treatment room including the impact of different pediatric patient sizes. MATERIALS AND METHODS: Working Group 9 of the...
Neural Population Dynamics Underlying Encoding of Time in the Cortico-Striatal Circuit
Francisca Martínez Traub
Jan 01, 0001
Interval timing, the ability to accurately measure elapsed time between events, is critical for generating appropriate behavioral responses. Research conducted over the past decades has implicated the cortico-striatal-thalamic...
Published by: Rockefeller University
PPR proteins - orchestrators of organelle RNA metabolism.
Pentatricopeptide repeat (PPR) proteins are important RNA regulators in chloroplasts and mitochondria, aiding in RNA editing, maturation, stabilisation or intron splicing, and in transcription and translation of organellar...
Galacto-conjugation of Navitoclax as an efficient strategy to increase senolytic specificity and reduce platelet toxicity.
Estela González-Gualda, Marta Pàez-Ribes, Beatriz Lozano-Torres, David Macias, Joseph R Wilson, Cristina González-López, Hui-Ling Ou, Sofía Mirón-Barroso, Zhenguang Zhang, Araceli Lérida-Viso, Juan F Blandez, Andrea Bernardos, Félix Sancenón, Miguel Rovira, Ljiljana Fruk, Carla P Martins, Manuel Serrano, Gary J Doherty, Ramón Martínez-Máñez, Daniel Muñoz-Espín
Mar 24, 2020
Pharmacologically active compounds with preferential cytotoxic activity for senescent cells, known as senolytics, can ameliorate or even revert pathological manifestations of senescence in numerous preclinical mouse disease...
Navitoclax (ABT-263) Cellular Senescence chemotherapy-induced senescence Lung cancer prodrug senolytics Thrombocytopenia Aniline Compounds Animals Antineoplastic Agents Apoptosis Blood Platelets Cell Survival Cellular Senescence Drug Screening Assays Antitumor Female Galactose Humans Mice Mice Inbred C57BL Mice SCID Molecular Structure Neoplasms Experimental prodrugs Sulfonamides Tumor Cells Cultured
Regions within a single epidermal cell of Drosophila can be planar polarised independently.
Planar cell polarity (PCP), the coordinated and consistent orientation of cells in the plane of epithelial sheets, is a fundamental and conserved property of animals and plants. Up to now, the smallest unit expressing PCP has...
G-quadruplexes are transcription factor binding hubs in human chromatin
Jochen Spiegel, Sergio Martínez Cuesta, Santosh Adhikari, Robert Hänsel-Hertsch, David Tannahill, Shankar Balasubramanian
Apr 23, 2021
Abstract: Background: The binding of transcription factors (TF) to genomic targets is critical in the regulation of gene expression. Short, double-stranded DNA sequence motifs are routinely implicated in TF recruitment, but many...
G-quadruplexes are transcription factor binding hubs in human chromatin.
Jochen Spiegel, Sergio Martínez Cuesta, Santosh Adhikari, Robert Hänsel-Hertsch, David Tannahill, Shankar Balasubramanian
Mar 26, 2021
Missing the missing values
Abstract: Nowadays, there is an increasing concern in machine learning about the causes underlying unfair decision making, that is, algorithmic decisions discriminating some groups over others, especially with groups that are...
Crystallization processes in bi-component thin film depositions:
The kinetic Monte Carlo (KMC) method is a powerful and simple tool to simulate the growth of thin films by deposition. However, one of its major drawbacks is the artificial order induced by the use of regular lattices. An...
Crystallization kinetic Monte Carlo Nanocomposite Polycrystal Thin film deposition /dk/atira/pure/subjectarea/asjc/1600/1600 name=General Chemistry /dk/atira/pure/subjectarea/asjc/3100/3104 name=Condensed Matter Physics /dk/atira/pure/subjectarea/asjc/2500/2505 name=Materials Chemistry /dk/atira/pure/subjectarea/asjc/2500/2508 name=Surfaces, Coatings and Films /dk/atira/pure/subjectarea/asjc/3100/3110 name=Surfaces and Interfaces
The Expression of Human Cytomegalovirus MicroRNA MiR-UL148D during Latent Infection in Primary Myeloid Cells Inhibits Activin A-triggered Secretion of IL-6.
Betty Lau, Emma Poole, Benjamin Krishna, Immaculada Sellart, Mark R Wills, Eain Murphy, John Sinclair
Aug 16, 2016
Crystallization processes in bi-component thin film depositions:
The kinetic Monte Carlo (KMC) method is a powerful and simple tool to simulate the growth of thin films by deposition. However, one of its major drawbacks is the artificial order induced by the use of regular lattices. An...
Crystallization kinetic Monte Carlo Nanocomposite Polycrystal Thin film deposition /dk/atira/pure/subjectarea/asjc/1600/1600 name=General Chemistry /dk/atira/pure/subjectarea/asjc/3100/3104 name=Condensed Matter Physics /dk/atira/pure/subjectarea/asjc/2500/2505 name=Materials Chemistry /dk/atira/pure/subjectarea/asjc/2500/2508 name=Surfaces, Coatings and Films /dk/atira/pure/subjectarea/asjc/3100/3110 name=Surfaces and Interfaces
Interwoven traditions in Bell Beaker metallurgy
Julia Montes-Landa, Mercedes Murillo-Barroso, Ignacio Montero-Ruiz, Salvador Rovira-Llorens, Marcos Martinón-Torres
Sep 13, 2021
Debates on early metallurgy in Western Europe have frequently focused on the social value of copper (between utilitarian and symbolic) and its purported role in the emergence and consolidation of hierarchies. Recent research...
A versatile drug delivery system targeting senescent cells.
Daniel Muñoz-Espín, Miguel Rovira, Irene Galiana, Cristina Giménez, Beatriz Lozano-Torres, Marta Paez-Ribes, Susana Llanos, Selim Chaib, Maribel Muñoz-Martín, Alvaro C Ucero, Guillermo Garaulet, Francisca Mulero, Stephen G Dann, Todd VanArsdale, David J Shields, Andrea Bernardos, José Ramón Murguía, Ramón Martínez-Máñez, Manuel Serrano
Sep 20, 2018
Senescent cells accumulate in multiple aging-associated diseases, and eliminating these cells has recently emerged as a promising therapeutic approach. Here, we take advantage of the high lysosomal β-galactosidase activity of...
Chemotherapy Fibrosis nanomedicine palbociclib Senescence Animals Cell Survival Cellular Senescence Cytotoxins Disease Models Animal Drug Compounding Drug Delivery Systems Fluorescent Dyes Galactose Heterografts Lysosomes Mice Neoplasm Transplantation Neoplasms Oligosaccharides Piperazines Pyridines Staining and Labeling beta-Galactosidase
On the Finite Element Implementation of Functionally Graded Materials.
Emilio Martínez-Pañeda
Feb 07, 2019
We investigate the numerical implementation of functionally graded properties in the context of the finite element method. The macroscopic variation of elastic properties inherent to functionally graded materials (FGMs) is...
Jordan’s self-fulfilling prophecy
JC Martínez
Jun 21, 2016
A Unified Abaqus Implementation of the Phase Field Fracture Method Using Only a User Material Subroutine.
We present a simple and robust implementation of the phase field fracture method in Abaqus. Unlike previous works, only a user material (UMAT) subroutine is used. This is achieved by exploiting the analogy between the phase...
Liver organoids reproduce alpha-1 antitrypsin deficiency-related liver disease
Gema Gómez-Mariano, Nerea Matamala, Selene Martínez, Iago Justo, Alberto Marcacuzco, Carlos Jimenez, Sara Monzón, Isabel Cuesta, Cristina Garfia, María Teresa Martínez, Meritxell Huch, Ignacio Pérez de Castro, Manuel Posada, Sabina Janciauskiene, Beatriz Martínez-Delgado
Jun 06, 2020
Abstract: Background and aims: Alpha-1 antitrypsin (AAT) is a product of SERPINA1 gene mainly expressed by hepatocytes. Clinically relevant mutations in the SERPINA1 gene, such as Z (Glu342Lys), results in an expression of...
Tool wear classification using time series imaging and deep learning
Abstract: Tool condition monitoring (TCM) has become essential to achieve high-quality machining as well as cost-effective production. Identification of the cutting tool state during machining before it reaches its failure stage...
Deconstructing a Hermeneutic Presupposition in Ricoeur’s The Symbolism of Evil
Hernán Martínez Millán
Mar 23, 2016
This paper critically analyzes Paul Ricoeurʼs presupposition that Plato’s philosophy was built on Orphism. In order to shed light on this central problematic issue in The Symbolism of Evil, this paper develops the following...
Published by: Memorial University of Newfoundland
Deconstructing a Hermeneutic Presupposition in Ricoeur’s The Symbolism of Evil
Hernán Martínez Millán
Mar 23, 2016
This paper critically analyzes Paul Ricoeurʼs presupposition that Plato’s philosophy was built on Orphism. In order to shed light on this central problematic issue in The Symbolism of Evil, this paper develops the following...
Published by: Memorial University of Newfoundland
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