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Results: 337
G-protein α-subunit (GPA1) regulates stress, nitrate and phosphate response, flavonoid biosynthesis, fruit/seed development and substantially shares GCR1 regulation in A. <i>thaliana</i>
Navjyoti Chakraborty, Priyanka Sharma, Kostya Kanyuka, Ravi Ramesh Pathak, Devapriya Choudhury, Richard Hooley, Nandula Raghuram
Dec 01, 2015
Heterotrimeric G-proteins are implicated in several plant processes, but the mechanisms of signal-response coupling and the roles of G-protein coupled receptors in general and GCR1 in particular, remain poorly understood. We...
G-protein α-subunit (GPA1) regulates stress, nitrate and phosphate response, flavonoid biosynthesis, fruit/seed development and substantially shares GCR1 regulation in A. <i>thaliana</i>
Navjyoti Chakraborty, Priyanka Sharma, Kostya Kanyuka, Ravi Ramesh Pathak, Devapriya Choudhury, Richard Hooley, Nandula Raghuram
Dec 01, 2015
Heterotrimeric G-proteins are implicated in several plant processes, but the mechanisms of signal-response coupling and the roles of G-protein coupled receptors in general and GCR1 in particular, remain poorly understood. We...
Can patient decision aids reduce decisional conflict in a de-escalation of breast radiotherapy clinical trial? The PRIMETIME Study Within a Trial implemented using a cluster stepped-wedge trial design
Indrani S. Bhattacharya, Joanne S. Haviland, Lesley Turner, Hilary Stobart, Ada Balasopoulou, Liba Stones, Anna M. Kirby, Cliona C. Kirwan, Charlotte E. Coles, Judith M. Bliss
Jun 14, 2021
Abstract: Background: For patients with early breast cancer considered at very-low risk of local relapse, risks of radiotherapy may outweigh the benefits. Decisions regarding treatment omission can lead to patient uncertainty...
Can patient decision aids reduce decisional conflict in a de-escalation of breast radiotherapy clinical trial? The PRIMETIME Study Within a Trial implemented using a cluster stepped-wedge trial design.
Indrani S Bhattacharya, Joanne S Haviland, Lesley Turner, Hilary Stobart, Ada Balasopoulou, Liba Stones, Anna M Kirby, Cliona C Kirwan, Charlotte E Coles, Judith M Bliss
Jul 28, 2021
Background
For patients with early breast cancer considered at very-low risk of local relapse, risks of radiotherapy may outweigh the benefits. Decisions regarding treatment omission can lead to patient uncertainty...
Cancer Breast cluster Radiotherapy oncology SWAT De-escalation stepped-wedge Decisional-conflict Humans Neoplasm Recurrence Local Chronic Disease Decision Making Decision Support Techniques Research Design Surveys and Questionnaires
Published by: Trials
Patient-Reported Outcomes Over 5 Years After Whole- or Partial-Breast Radiotherapy
Indrani S Bhattacharya, Joanne S Haviland, Anna M Kirby, Cliona C Kirwan, Penelope Hopwood, John R Yarnold, Judith M Bliss, Charlotte E Coles, IMPORT Trialists
Jan 15, 2019
Aged Anxiety Body Image Breast Neoplasms Depression Female Humans Incidence Longitudinal Studies Middle Aged Patient Reported Outcome Measures prevalence Quality of life Radiation Dose Hypofractionation Radiation Injuries Radiotherapy Adjuvant Risk Assessment Risk Factors Time Factors Treatment Outcome
Studies Towards the Discovery of Novel Natural Products Through Functional Analysis of Environmental DNA-Encoded Type II Polyketide Synthases
Debjani Chakraborty
Jan 01, 0001
Natural products have historically served as a major source for most of the therapeutically relevant compounds. A significant fraction of these natural product-based drugs and leads are derived from microorganisms. Although the...
Published by: Rockefeller University
Can patient-reported outcomes be used instead of clinician-reported outcomes and photographs as primary endpoints of late normal tissue effects in breast radiotherapy trials? Results from the IMPORT LOW trial.
Indrani S Bhattacharya, Joanne S Haviland, Penelope Hopwood, Charlotte E Coles, John R Yarnold, Judith M Bliss, Anna M Kirby, IMPORT Trialists
Mar 07, 2019
BACKGROUND: In an era of low local relapse rates after adjuvant breast radiotherapy, risks of late normal-tissue effects (NTE) need to be balanced against risk of relapse. NTE are assessed using patient-reported outcome measures...
Breast Normal tissue effects PROMs Patient-reported Radiotherapy Trials Adult Breast Neoplasms Clinical Trials Phase III as Topic Combined Modality Therapy Disease Progression Endpoint Determination Female Humans Middle Aged Neoplasm Recurrence Local Patient Reported Outcome Measures Photography Radiotherapy Radiotherapy Adjuvant Randomized Controlled Trials as Topic
Can patient decision aids reduce decisional conflict in a de-escalation of breast radiotherapy clinical trial? The PRIMETIME Study Within a Trial implemented using a cluster stepped-wedge trial design.
Indrani S Bhattacharya, Joanne S Haviland, Lesley Turner, Hilary Stobart, Ada Balasopoulou, Liba Stones, Anna M Kirby, Cliona C Kirwan, Charlotte E Coles, Judith M Bliss, PRIMETIME Trialists
Jul 12, 2021
BACKGROUND: For patients with early breast cancer considered at very-low risk of local relapse, risks of radiotherapy may outweigh the benefits. Decisions regarding treatment omission can lead to patient uncertainty (decisional...
An Approach to Prevent Air Pollution and Generate Electricity Using Nanostructured Carbon Materials
Pollution is one of the major threats for the environment as well as society. It causes severe problems for the living organisms and can gives birth of various unknown issues. Different sources like cars, industrial belts...
Published by: IGI Global Scientific Publishing
Is breast seroma after tumour resection associated with patient-reported breast appearance change following radiotherapy? Results from the IMPORT HIGH (CRUK/06/003) trial.
Indrani S Bhattacharya, Joanne S Haviland, Carola Perotti, David Eaton, Sarah Gulliford, Emma Harris, Charlotte E Coles, Cliona C Kirwan, Judith M Bliss, Anna M Kirby, IMPORT Trialists
Apr 05, 2019
BACKGROUND: Seroma describes a collection of serous fluid within a cavity, occurring following surgery. Seroma is associated with normal tissue effects (NTE) following breast radiotherapy, as reported by clinicians and on...
Charge transport in cancer-related genes and early carcinogenesis
The electronic transmission properties of DNA molecules are believed to play a significant role in many physical phenomena taking place in living organisms (Chakraborty, 2007) [1]. Here we study the charge transport (CT)...
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