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Antibiotic Therapy and the Gut Microbiome
Stephen A Kelly, Jonathan Nzakizwanayo, Aoife M Rodgers, Li Zhao, Rebecca Weiser, Ismaiel A Tekko, Helen O McCarthy, Rebecca J Ingram, Brian V Jones, Ryan F Donnelly, Brendan F Gilmore
May 14, 2021
The contribution of the gut microbiome to human health has long been established, with normal gut microbiota conferring protection against invasive pathogens. Antibiotics can disrupt the microbial balance of the gut...
Antibiotic Therapy and the Gut Microbiome
Stephen A Kelly, Jonathan Nzakizwanayo, Aoife M Rodgers, Li Zhao, Rebecca Weiser, Ismaiel A Tekko, Helen O McCarthy, Rebecca J Ingram, Brian V Jones, Ryan F Donnelly, Brendan F Gilmore
May 14, 2021
The contribution of the gut microbiome to human health has long been established, with normal gut microbiota conferring protection against invasive pathogens. Antibiotics can disrupt the microbial balance of the gut...
Philip McShane
Ivo Coelho
Mar 16, 2022
Ivo Coelho, SDB earned a PhD in philosophy at the Gregorian University, Rome, for his work on “The Development of the Notion of the Universal Viewpoint in Bernard Lonergan: From Insight to Method in Theology” (1994). Among his...
Published by: Memorial University of Newfoundland
Dialectic Exercise on *Method in Theology,* Chapter 5
Ivo Coelho
Nov 12, 2022
Ivo Coelho, SDB earned a PhD in philosophy at the Gregorian University, Rome, for his work on “The Development of the Notion of the Universal Viewpoint in Bernard Lonergan: From Insight to Method in Theology” (1994). Among his...
Published by: Memorial University of Newfoundland
Dialectic Exercise on *Method in Theology,* Chapter 5
Ivo Coelho
Nov 12, 2022
Ivo Coelho, SDB earned a PhD in philosophy at the Gregorian University, Rome, for his work on “The Development of the Notion of the Universal Viewpoint in Bernard Lonergan: From Insight to Method in Theology” (1994). Among his...
Published by: Memorial University of Newfoundland
Philip McShane
Ivo Coelho
Mar 16, 2022
Ivo Coelho, SDB earned a PhD in philosophy at the Gregorian University, Rome, for his work on “The Development of the Notion of the Universal Viewpoint in Bernard Lonergan: From Insight to Method in Theology” (1994). Among his...
Published by: Memorial University of Newfoundland
Information recovery from low coverage whole-genome bisulfite sequencing.
Emanuele Libertini, Simon C Heath, Rifat A Hamoudi, Marta Gut, Michael J Ziller, Agata Czyz, Victor Ruotti, Hendrik G Stunnenberg, Mattia Frontini, Willem H Ouwehand, Alexander Meissner, Ivo G Gut, Stephan Beck
Sep 08, 2018
The cost of whole-genome bisulfite sequencing (WGBS) remains a bottleneck for many studies and it is therefore imperative to extract as much information as possible from a given dataset. This is particularly important because...
Nutrient-Induced Cellular Mechanisms of Gut Hormone Secretion.
The gastrointestinal tract can assess the nutrient composition of ingested food. The nutrient-sensing mechanisms in specialised epithelial cells lining the gastrointestinal tract, the enteroendocrine cells, trigger the release...
Nutrient-Induced Cellular Mechanisms of Gut Hormone Secretion
The gastrointestinal tract can assess the nutrient composition of ingested food. The nutrient-sensing mechanisms in specialised epithelial cells lining the gastrointestinal tract, the enteroendocrine cells, trigger the release...
Bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator
David T. Riglar, David L. Richmond, Laurent Potvin-Trottier, Andrew A. Verdegaal, Alexander D. Naydich, Somenath Bakshi, Emanuele Leoncini, Lorena G. Lyon, Johan Paulsson, Pamela A. Silver
Oct 10, 2020
Abstract: Synthetic gene oscillators have the potential to control timed functions and periodic gene expression in engineered cells. Such oscillators have been refined in bacteria in vitro, however, these systems have lacked the...
Bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator.
David T Riglar, David L Richmond, Laurent Potvin-Trottier, Andrew A Verdegaal, Alexander D Naydich, Somenath Bakshi, Emanuele Leoncini, Lorena G Lyon, Johan Paulsson, Pamela A Silver
Dec 11, 2019
Synthetic gene oscillators have the potential to control timed functions and periodic gene expression in engineered cells. Such oscillators have been refined in bacteria in vitro, however, these systems have lacked the...
Impact of global PTP1B deficiency on the gut barrier permeability during NASH in mice.
Carmen Rubio, Marta Puerto, Juan J García-Rodríquez, Van B Lu, Irma García-Martínez, Rosa Alén, Patricia Sanmartín-Salinas, M Val Toledo-Lobo, Jorge Saiz, Javier Ruperez, Coral Barbas, Luis Menchén, Fiona M Gribble, Frank Reimann, Luis G Guijarro, Jose M Carrascosa, Ángela M Valverde
May 05, 2020
OBJECTIVE:Non-alcoholic steatohepatitis (NASH) is characterized by a robust pro-inflammatory component at both hepatic and systemic levels together with a disease-specific gut microbiome signature. Protein tyrosine phosphatase...
Published by: Molecular metabolism
Diet induces parallel changes to the gut microbiota and problem solving performance in a wild bird
Gabrielle L. Davidson, Niamh Wiley, Amy C. Cooke, Crystal N. Johnson, Fiona Fouhy, Michael S. Reichert, Iván de la Hera, Jodie M. S. Crane, Ipek G. Kulahci, R. Paul Ross, Catherine Stanton, John L. Quinn
Nov 27, 2020
Abstract: The microbial community in the gut is influenced by environmental factors, especially diet, which can moderate host behaviour through the microbiome-gut-brain axis. However, the ecological relevance of...
Gut Hormone Regulation and Secretion via FFA1 and FFA4.
The digestion, absorption and utilisation of dietary triglycerides are controlled by gut hormones, released from enteroendocrine cells along the length of the gastrointestinal tract. Major players in the detection of ingested...
Diet induces parallel changes to the gut microbiota and problem solving performance in a wild bird.
Gabrielle L Davidson, Niamh Wiley, Amy C Cooke, Crystal N Johnson, Fiona Fouhy, Michael S Reichert, Iván de la Hera, Jodie MS Crane, Ipek G Kulahci, R Paul Ross, Catherine Stanton, John L Quinn
Dec 10, 2020
The microbial community in the gut is influenced by environmental factors, especially diet, which can moderate host behaviour through the microbiome-gut-brain axis. However, the ecological relevance of microbiome-mediated...
G-Quadruplexes
Guanine (G)-rich sequences in nucleic acids can assemble into G-quadruplex structures that involve G-quartets linked by loop nucleotides. The structural and topological diversity of G-quadruplexes have attracted great attention...
Baseline Gut Microbiota Composition Is Associated With Schistosoma mansoni Infection Burden in Rodent Models.
Alba Cortés, Simon Clare, Alice Costain, Alexandre Almeida, Catherine McCarthy, Katherine Harcourt, Cordelia Brandt, Charlotte Tolley, James Rooney, Matthew Berriman, Trevor Lawley, Andrew S MacDonald, Gabriel Rinaldi, Cinzia Cantacessi
Oct 22, 2020
In spite of growing evidence supporting the occurrence of complex interactions between Schistosoma and gut bacteria in mice and humans, no data is yet available on whether worm-mediated changes in microbiota composition are...
Schistosoma mansoni Dysbiosis gut microbial diversity helminth-gut microbiota interactions human-microbiota associated mouse models immune-modulation Animals Antibodies Protozoan Bacteria Biodiversity Computational Biology Disease Models Animal Dysbiosis Feces Gastrointestinal Microbiome host-parasite interactions immunomodulation Metagenomics Mice Parasite Load RNA Ribosomal 16S Schistosoma Schistosomiasis mansoni
Baseline Gut Microbiota Composition Is Associated With Schistosoma mansoni Infection Burden in Rodent Models
Alba Cortés, Simon Clare, Alice Costain, Alexandre Almeida, Catherine McCarthy, Katherine Harcourt, Cordelia Brandt, Charlotte Tolley, James Rooney, Matthew Berriman, Trevor Lawley, Andrew S. MacDonald, Gabriel Rinaldi, Cinzia Cantacessi
Dec 02, 2020
In spite of growing evidence supporting the occurrence of complex interactions between Schistosoma and gut bacteria in mice and humans, no data is yet available on whether worm-mediated changes in microbiota composition are...
Taxonomic signatures of cause-specific mortality risk in human gut microbiome.
Aaro Salosensaari, Ville Laitinen, Aki S Havulinna, Guillaume Meric, Susan Cheng, Markus Perola, Liisa Valsta, Georg Alfthan, Michael Inouye, Jeramie D Watrous, Tao Long, Rodolfo A Salido, Karenina Sanders, Caitriona Brennan, Gregory C Humphrey, Jon G Sanders, Mohit Jain, Pekka Jousilahti, Veikko Salomaa, Rob Knight, Leo Lahti, Teemu Niiranen
Jun 12, 2021
The collection of fecal material and developments in sequencing technologies have enabled standardised and non-invasive gut microbiome profiling. Microbiome composition from several large cohorts have been cross-sectionally...
Synthesis of Novel Regenerable 13X Zeolite-Polyimide Adsorbent Foams
A new generic synthesis method is presented for the production of a polyimide (PI)/adsorbent (80 wt% 13X zeolite) regenerable foam filter. The method uses a dual parallel reaction foaming process comprising CO 2...
Adsorbent foam Adsorption Air Filters Isotherms modelling Polyimide /dk/atira/pure/subjectarea/asjc/1600/1600 name=General Chemistry /dk/atira/pure/subjectarea/asjc/2300/2304 name=Environmental Chemistry /dk/atira/pure/subjectarea/asjc/1500/1500 name=General Chemical Engineering /dk/atira/pure/subjectarea/asjc/2200/2209 name=Industrial and Manufacturing Engineering
Remote stereocontrol in [3,3]-sigmatropic rearrangements
The Ireland - Claisen [3,3]-sigmatropic rearrangement has been used to access biologically important β,β′-dihydroxy α-amino acids. The rearrangement reported is highly stereoselective and offers excellent levels of remote...
Synthesis of Novel Regenerable 13X Zeolite-Polyimide Adsorbent Foams
A new generic synthesis method is presented for the production of a polyimide (PI)/adsorbent (80 wt% 13X zeolite) regenerable foam filter. The method uses a dual parallel reaction foaming process comprising CO 2...
Adsorbent foam Adsorption Air Filters Isotherms modelling Polyimide /dk/atira/pure/subjectarea/asjc/1600/1600 name=General Chemistry /dk/atira/pure/subjectarea/asjc/2300/2304 name=Environmental Chemistry /dk/atira/pure/subjectarea/asjc/1500/1500 name=General Chemical Engineering /dk/atira/pure/subjectarea/asjc/2200/2209 name=Industrial and Manufacturing Engineering
Response of the human gut and saliva microbiome to urbanization in Cameroon.
Ana Lokmer, Sophie Aflalo, Norbert Amougou, Sophie Lafosse, Alain Froment, Francis Ekwin Tabe, Mathilde Poyet, Mathieu Groussin, Rihlat Said-Mohamed, Laure Ségurel
May 18, 2020
Urban populations from highly industrialized countries are characterized by a lower gut bacterial diversity as well as by changes in composition compared to rural populations from less industrialized countries. To unveil the...
Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation.
Arie B Brinkman, Serena Nik-Zainal, Femke Simmer, F Germán Rodríguez-González, Marcel Smid, Ludmil B Alexandrov, Adam Butler, Sancha Martin, Helen Davies, Dominik Glodzik, Xueqing Zou, Manasa Ramakrishna, Johan Staaf, Markus Ringnér, Anieta Sieuwerts, Anthony Ferrari, Sandro Morganella, Thomas Fleischer, Vessela Kristensen, Marta Gut, Marc J van de Vijver, Anne-Lise Børresen-Dale, Andrea L Richardson, GIlles Thomas, Ivo G Gut, John WM Martens, John A Foekens, Michael R Stratton, Hendrik G Stunnenberg
May 03, 2019
Global loss of DNA methylation and CpG island (CGI) hypermethylation are key epigenomic aberrations in cancer. Global loss manifests itself in partially methylated domains (PMDs) which extend up to megabases. However, the...
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