Conditions such as small for gestational age (SGA), which is defined as birthweight less than 10th percentile for gestational age can predispose to neurodevelopmental abnormalities compared to babies with normal birthweight....
Twinning and placental fusion occur at a low frequency in species like humans and mice. They are linked to reduced birth weight and intertwin growth discrepancy with important consequences for perinatal survival. Despite this...
During pregnancy, the mother must adapt her body systems to support nutrient and oxygen supply for growth of the baby in utero and during the subsequent lactation. These include changes in the cardiovascular, pulmonary, immune...
Exposures to adverse conditions in utero can lead to permanent changes in the structure and function of key physiological systems in the developing fetus, increasing the risk of disease and premature aging in later postnatal...
NEW FINDINGS: What is the topic of this review? How the placenta, which transports nutrients and oxygen to the fetus, may alter its support of fetal growth developmentally and with adverse gestational conditions. What advances...
A study of B+→ J/ψηK+ decays, followed by J/ψ → μ+μ− and η → γγ, is performed using a dataset collected with the LHCb detector in proton-proton collisions at centre-of-mass energies of 7, 8 and 13 TeV, corresponding to an...
In mice, the labyrinth zone of the placenta exchanges nutrients and gases between mother and fetus. This placental zone is complex in structure and defects in its morphogenesis can compromise substrate exchange and thus, fetal...
A study of $B_c^+\to J/\psi D_s^+$ and $B_c^+\to J/\psi D_s^{*+}$ decays
using 139 fb$^{-1}$ of integrated luminosity collected with the ATLAS detector
from $\sqrt{s} = 13$ TeV $pp$ collisions at the LHC is presented. The ratios...
Pregnancy is a remarkable physiological state, during which the metabolic system of the mother adapts to ensure that nutrients are made available for transfer to the fetus for growth and development. Adaptations of maternal...
Abstract: A measurement of the production of a prompt J/ψ meson in association with a W± boson with W± → μν and J/ψ → μ+μ− is presented for J/ψ transverse momenta in the range 8.5–150 GeV and rapidity |yJ/ψ| < 2.1 using ATLAS...
Abstract: A measurement of the production of a prompt J/ψ meson in association with a W± boson with W± → μν and J/ψ → μ+μ− is presented for J/ψ transverse momenta in the range 8.5–150 GeV and rapidity |yJ/ψ| < 2.1 using ATLAS...
A study of $B^+ \rightarrow J/\psi \eta K^+$ decays, followed by $J/\psi
\rightarrow \mu^+ \mu^-$ and $\eta \rightarrow \gamma \gamma$, is performed
using a dataset collected with the LHCb detector in proton-proton collisions...
Octahedral platinum(iv) complexes such as trans,trans,trans-[Pt(N3)2(OH)2(pyridine)2] (1) are stable in the dark, but potently cytotoxic to a range of cancer cells when activated by UVA or visible light, and active in vivo....
The gut microbiota plays a central role in regulating host metabolism. While substantial progress has been made in discerning how the microbiota influences host functions post birth and beyond, little is known about how key...
Intrauterine growth restriction (IUGR) affects approximately 10% of human pregnancies globally and has immediate and life-long consequences for offspring health. However, the mechanisms underlying the pathogenesis of IUGR and...
Abstract: The decays Bs0 → J/ψπ+π−K+K− are studied using a data set corresponding to an integrated luminosity of 9 fb−1, collected with the LHCb detector in proton-proton collisions at centre-of-mass energies of 7, 8 and 13 TeV....
Fetal growth is reliant on placental formation and function, which, in turn, requires the energy produced by the mitochondria. Prior work has shown that both mother and fetus operate via the phosphoinositol 3-kinase (PI3K)-p110α...
Adverse maternal environments such as small size, malnutrition, and metabolic conditions are known to influence fetal growth outcomes. Similarly, fetal growth and metabolic alterations may alter the intrauterine environment and...
Abstract: The decays Bs0 → J/ψπ+π−K+K− are studied using a data set corresponding to an integrated luminosity of 9 fb−1, collected with the LHCb detector in proton-proton collisions at centre-of-mass energies of 7, 8 and 13 TeV....
Abstract: The decays B+→ J/ψπ+π−K+ are studied using a data set corresponding to an integrated luminosity of 9 fb−1 collected with the LHCb detector in proton-proton collisions between 2011 and 2018. Precise measurements of the...