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De Finetti and Savage on the normative relevance of imprecise reasoning
This paper examines the claim that de Finetti and Savage completely rejected the notion of indeterminate, as distinct from imprecise, probabilities. It argues that their examination of imprecise reasoning refers both to...
Winthrop Recognizes Exceptional Employees During Annual Ceremony
Winthrop University
Jan 01, 0001
Winthrop University honored 41 employees with presidential citations during the April 23 Faculty, Staff and Retirees Awards Ceremony. Retirees Glenn Savage and Lynn Harand were co-recipients of the Mary Spann Richardson Award....
Published by: Winthrop University
Combined genetic deletion of GDF15 and FGF21 has modest effects on body weight, hepatic steatosis and insulin resistance in high fat fed mice.
David Savage
Oct 06, 2022
Objectives
Obesity in humans and mice is associated with elevated levels of two hormones responsive to cellular stress, namely GDF15 and FGF21. Over-expression of each of these is associated with weight loss and beneficial...
Genetic syndromes of severe insulin resistance.
Insulin resistance underpins the link between obesity and most of its associated metabolic disorders including type 2 diabetes, fatty liver disease, dyslipidaemia and cardiovascular disease. Despite its importance and extensive...
Vernon Lee's Problem with Landor
Alex T Wong
Feb 03, 2016
This article considers some fundamental elements of Vernon Lee’s critical theory by focussing attention on her criticisms of Walter Savage Landor, whose ‘classical’ or ‘rhetorical’ style she attributes to the writer’s lack of...
Gene-gene and gene-environment interactions in lipodystrophy
Monogenic lipodystrophies are a heterogeneous group of rare disorders characterized by a lack of adipose tissue (AT), all of which predispose patients to the development of insulin resistance and its related metabolic sequelae....
Further Evidence for the Minifilament-eruption Scenario for Solar Polar Coronal Jets
Abstract
We examine a sampling of 23 polar-coronal-hole jets. We first identified the jets in soft X-ray (SXR) images from the X-ray telescope (XRT) on the Hinode spacecraft, over...
Turn-taking in cooperative offspring care
ABSTRACT: For individuals collaborating to rear offspring, effective organization of resource delivery is difficult because each carer benefits when the others provide a greater share of the total investment required. When...
The Strange Use of דגל in Song of Songs 5
JL Andruska
May 16, 2017
The use of the word דגל in the Song of Songs 5:10 has caused considerable confusion among commentators. Most occurrences of the word in the Song are thought to be related to an army or host carrying banners, except in 5:10...
Computing the quasinormal modes and eigenfunctions for the Teukolsky equation using horizon penetrating, hyperboloidally compactified coordinates
JL Ripley
Jul 08, 2022
We study the quasinormal mode eigenvalues and eigenfunctions for the
Teukolsky equation in a horizon penetrating, hyperboloidally compactified
(HPHC) coordinate system. Following earlier work by Zengino\u{g}lu
(arXiv:1102.2451)...
Filopodia and their links with membrane traffic and cell adhesion.
JL Gallop
Dec 09, 2019
Filopodia are dynamic, narrow, plasma membrane protrusions filled with bundled actin filaments. Fresh actin monomers are incorporated at the tips furthest away from the cell body, where barbed end polymerases such as formins and...
Geometry driven type II higher dimensional blow-up for the critical heat equation
We consider the problem vt=Δv+|v|p−1vin Ω×(0,T),v=0on ∂Ω×(0,T),v>0in Ω×(0,T). In a domain Ω⊂Rd, d≥7 enjoying special symmetries, we find the first example of a solution with type II blow-up...
"We're stuck with what we've got"
AIMS AND OBJECTIVES: To evaluate the impact of lipodystrophy on body image and how this affects patients' daily lives. BACKGROUND: Lipodystrophy refers to a group of rare conditions characterised by generalised or partial lack...
Geometry driven type II higher dimensional blow-up for the critical heat equation
We consider the problem vt=Δv+|v|p−1vin Ω×(0,T),v=0on ∂Ω×(0,T),v>0in Ω×(0,T). In a domain Ω⊂Rd, d≥7 enjoying special symmetries, we find the first example of a solution with type II blow-up...
Machine learning for target discovery in drug development.
Chemical probes Chemical proteomics Drug Discovery Machine Learning target identification Antineoplastic Agents Computer Simulation Drug Evaluation Preclinical Humans lipoxygenase Machine Learning Molecular Targeted Therapy Naphthoquinones Pentacyclic Triterpenes Proteomics Receptors Cannabinoid Sesquiterpenes Sesquiterpenes Guaiane Transient Receptor Potential Channels
Novel application of internal obturator and semitendinosus muscle flaps for rectal wall repair or reinforcement.
Internal obturator and/or semitendinosus muscle flaps were used to reinforce primary appositional rectal wall repair in three dogs and one cat in this case series. All three dogs incurred rectal wall compromise during surgical...
Alison Sleigh, David B Savage, Guy B Williams, David Porter, T Adrian Carpenter, Kevin M Brindle, Graham J Kemp
Jan 06, 2016
Simple and effective exercise design for assessing in vivo mitochondrial function in clinical applications using (31)P magnetic resonance spectroscopy.
Alison Sleigh, Victoria Lupson, Ajay Thankamony, David B Dunger, David B Savage, T Adrian Carpenter, Graham J Kemp
Dec 04, 2015
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