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Alcohol consumption in relation to cardiovascular diseases and mortality
The causal effects of alcohol-in-moderation on cardiometabolic health are continuously debated. Mendelian randomization (MR) is an established method to address causal questions in observational studies. We performed a...
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Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes
AIMS/HYPOTHESIS: Here, we describe the characteristics of the Innovative Medicines Initiative (IMI) Diabetes Research on Patient Stratification (DIRECT) epidemiological cohorts at baseline and follow-up examinations (18, 36 and...
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Predicting and elucidating the etiology of fatty liver disease
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is highly prevalent and causes serious health complications in individuals with and without type 2 diabetes (T2D). Early diagnosis of NAFLD is important, as this can help...
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Cardiovascular Risk Factors Associated With Venous Thromboembolism.
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