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Results: 1491
Pathogenic variants in MT-ATP6
Yi Shiau Ng, Mika H Martikainen, Gráinne S Gorman, Alasdair Blain, Enrico Bugiardini, Apphia Bunting, Andrew M Schaefer, Charlotte L Alston, Emma L Blakely, Sunil Sharma, Imelda Hughes, Albert Lim, Christian de Goede, Meriel McEntagart, Stefan Spinty, Iain Horrocks, Mark Roberts, Cathy E Woodward, Patrick F Chinnery, Rita Horvath, Victoria Nesbitt, Carl Fratter, Joanna Poulton, Michael G Hanna, Robert DS Pitceathly, Robert W Taylor, Doug M Turnbull, Robert McFarland
Jun 28, 2019
Distinct clinical syndromes have been associated with pathogenic MT-ATP6 variants. In this cohort study, we identified 125 individuals (60 families) including 88 clinically affected individuals and 37 asymptomatic carriers....
MT-HESS
Alex Lewin, Habib Saadi, James E Peters, Aida Moreno-Moral, James C Lee, Kenneth GC Smith, Enrico Petretto, Leonardo Bottolo, Sylvia Richardson
Sep 05, 2018
MOTIVATION: Analysing the joint association between a large set of responses and predictors is a fundamental statistical task in integrative genomics, exemplified by numerous expression Quantitative Trait Loci (eQTL) studies. Of...
Algorithms Animals Bayes Theorem Diabetes mellitus Type 1 Gene Expression Regulation Gene Regulatory Networks Genomics Humans Inflammation Inflammatory Bowel Diseases Models Theoretical Organ Specificity Polymorphism Single Nucleotide Programming Languages Quantitative Trait Loci Rats Software Tissue Distribution
Designing Controlled Chinese Rules for MT Pre-Editing of Product Description Text
The study aims to investigate how pre-editing based on controlled Chinese rules can be an effective approach to improving Chinese-to-English machine translation (MT) output. Based on the analysis of comparable texts, and by...
Published by: IGI Global Scientific Publishing
Tumour microbiomes and Fusobacterium genomics in Vietnamese colorectal cancer patients.
Hoang NH Tran, Trang Nguyen Hoang Thu, Phu Huu Nguyen, Chi Nguyen Vo, Khanh Van Doan, Chau Nguyen Ngoc Minh, Ngoc Tuan Nguyen, Van Ngoc Duc Ta, Khuong An Vu, Thanh Danh Hua, To Nguyen Thi Nguyen, Tan Trinh Van, Trung Pham Duc, Ba Lap Duong, Phuc Minh Nguyen, Vinh Chuc Hoang, Duy Thanh Pham, Guy E Thwaites, Lindsay J Hall, Daniel J Slade, Stephen Baker, Vinh Hung Tran, Hao Chung The
Nov 28, 2022
Perturbations in the gut microbiome have been associated with colorectal cancer (CRC), with the colonic overabundance of Fusobacterium nucleatum shown as the most consistent marker. Despite its significance in the promotion of...
Heat Engine Drives Transport of an FeII 4 L4 Cage and Cargo.
Bao-Nguyen T Nguyen, Angela B Grommet, Arnaud Tron, Maureen CA Georges, Jonathan R Nitschke
May 06, 2020
The directed motion of species against a chemical potential gradient is a fundamental feature of living systems, underpinning processes that range from transport through cell membranes to neurotransmission. The development of...
Interior Design Student Places Second in National Competition
Winthrop University
Jan 01, 0001
Nguyen was inspired by the avant-garde style and its exposed forms for his piece, "Mecha Wave." His second-place finish comes with a $1,500 scholarship. Winthrop University student Tung Nguyen has won second place in the...
Published by: Winthrop University
Tumour microbiomes and Fusobacterium genomics in Vietnamese colorectal cancer patients.
Hoang NH Tran, Trang Nguyen Hoang Thu, Phu Huu Nguyen, Chi Nguyen Vo, Khanh Van Doan, Chau Nguyen Ngoc Minh, Ngoc Tuan Nguyen, Van Ngoc Duc Ta, Khuong An Vu, Thanh Danh Hua, To Nguyen Thi Nguyen, Tan Trinh Van, Trung Pham Duc, Ba Lap Duong, Phuc Minh Nguyen, Vinh Chuc Hoang, Duy Thanh Pham, Guy E Thwaites, Lindsay J Hall, Daniel J Slade, Stephen Baker, Vinh Hung Tran, Hao Chung The
Oct 29, 2022
Perturbations in the gut microbiome have been associated with colorectal cancer (CRC), with the colonic overabundance of Fusobacterium nucleatum shown as the most consistent marker. Despite its significance in the promotion of...
The emergence of azithromycin-resistant Salmonella Typhi in Nepal.
Pham Thanh Duy, Sabina Dongol, Abhishek Giri, Nguyen Thi Nguyen To, Ho Ngoc Dan Thanh, Nguyen Pham Nhu Quynh, Pham Duc Trung, Guy E Thwaites, Buddha Basnyat, Stephen Baker, Maia A Rabaa, Abhilasha Karkey
May 17, 2021
BACKGROUND: Typhoid fever remains a significant cause of morbidity and mortality in Asia and Africa. The emergence of azithromycin resistance in South Asia is concerning, as azithromycin is one of the last effective oral drugs...
Improvements to ultrasonic beamformer design and implementation derived from the task-based analytical framework
The task-based framework, previously developed for beamformer comparison [Nguyen, Prager, and Insana, J. Acoust. Soc. Am. 140, 1048–1059 (2016)], is extended to design a new beamformer with potential applications in breast...
Viral Metagenomic Analysis of Cerebrospinal Fluid from Patients with Acute Central Nervous System Infections of Unknown Origin, Vietnam.
Nguyen To Anh, Le Nguyen Truc Nhu, Nguyen Thi Thu Hong, Tran My Phuc, Pham Thi Thanh Tam, Dang Thao Huong, Tran Tuan Anh, Xutao Deng, Ho Dang Trung Nghia, Tran Thua Nguyen, Nguyen Van Hung, Nguyen Dac Thuan, Pham Thi Hong Phuong, Nguyen Van Vinh Chau, Stephen Baker, Eric Delwart, Guy Thwaites, Le Van Tan, VIZIONS Consortium1
May 17, 2021
Central nervous system (CNS) infection is a serious neurologic condition, although the etiology remains unknown in >50% of patients. We used metagenomic next-generation sequencing to detect viruses in 204 cerebrospinal fluid...
Clinical and laboratory factors associated with neonatal sepsis mortality at a major Vietnamese children's hospital.
Nguyen Duc Toan, Thomas C Darton, Nguyen Hoang Thien Huong, Le Thanh Hoang Nhat, To Nguyen Thi Nguyen, Ha Thanh Tuyen, Le Quoc Thinh, Nguyen Kien Mau, Pham Thi Thanh Tam, Cam Ngoc Phuong, Le Nguyen Thanh Nhan, Ngo Ngoc Quang Minh, Ngo Minh Xuan, Tang Chi Thuong, Nguyen Thanh Hung, Christine Boinett, Stephen Reece, Abhilasha Karkey, Jeremy N Day, Stephen Baker
Apr 17, 2023
Sepsis is a major cause of neonatal mortality and children born in low- and middle-income countries (LMICs) are at greater risk of severe neonatal infections than those in higher-income countries. Despite this disparity, there...
Published by: PLOS global public health
A Double-blind, Randomized, Placebo-controlled Trial of Lactobacillus acidophilus for the Treatment of Acute Watery Diarrhea in Vietnamese Children.
Tran Thi Hong Chau, Nguyen Ngoc Minh Chau, Nhat Thanh Hoang Le, Hao Chung The, Phat Voong Vinh, Nguyen Thi Nguyen To, Nguyen Minh Ngoc, Ha Manh Tuan, Tang Le Chau Ngoc, Marion-Eliette Kolader, Jeremy J Farrar, Marcel Wolbers, Guy E Thwaites, Stephen Baker, Oxford-Vietnam Probiotics Study Group
Aug 02, 2019
Living Afterwards
Trudi Tate
Dec 07, 2018
This article explores the writings of two Vietnamese-American writers, former refugees: Viet Nguyen and Le Thi Diem Thuy.
Clinical and laboratory factors associated with neonatal sepsis mortality at a major Vietnamese children's hospital.
Nguyen Duc Toan, Thomas C Darton, Nguyen Hoang Thien Huong, Le Thanh Hoang Nhat, To Nguyen Thi Nguyen, Ha Thanh Tuyen, Le Quoc Thinh, Nguyen Kien Mau, Pham Thi Thanh Tam, Cam Ngoc Phuong, Le Nguyen Thanh Nhan, Ngo Ngoc Quang Minh, Ngo Minh Xuan, Tang Chi Thuong, Nguyen Thanh Hung, Christine Boinett, Stephen Reece, Abhilasha Karkey, Jeremy N Day, Stephen Baker
Sep 02, 2022
Sepsis is a major cause of neonatal mortality and children born in low- and middle-income countries (LMICs) are at greater risk of severe neonatal infections than those in higher-income countries. Despite this disparity, there...
Patient Safety Infant Mortality Hematology Sepsis Pediatric Clinical Research Infectious Diseases Perinatal Period - Conditions Originating in Perinatal Period 4.1 Discovery and preclinical testing of markers and technologies 4 Detection screening and diagnosis Infection Inflammatory and immune system 3 Good Health and Well Being
Pathogenic mtDNA mutations causing mitochondrial myopathy
Steven A Hardy, Emma L Blakely, Andrew I Purvis, Mariana C Rocha, Syeda Ahmed, Gavin Falkous, Joanna Poulton, Michael R Rose, Olivia O'Mahony, Niamh Bermingham, Charlotte F Dougan, Yi Shiau Ng, Rita Horvath, Doug M Turnbull, Grainne S Gorman, Robert W Taylor
Oct 01, 2019
Pathogenic mitochondrial tRNA (mt-tRNA) gene mutations represent a prominent cause of primary mitochondrial DNA (mtDNA)-related disease despite accounting for only 5%-10% of the mitochondrial genome.(1,2) Although some common...
Invasive Non-typhoidal Salmonella Infections in Asia
Nguyen Phu Huong Lan, Tu Le Thi Phuong, Hien Nguyen Huu, Le Thuy, Alison E Mather, Se Eun Park, Florian Marks, Guy E Thwaites, Nguyen Van Vinh Chau, Corinne N Thompson, Stephen Baker
Feb 19, 2019
Invasive non-typhoidal Salmonella (iNTS) infections are now a well-described cause of morbidity and mortality in children and HIV-infected adults in sub-Saharan Africa. In contrast, the epidemiology and clinical manifestations...
Adult Aged Anti-Infective Agents Ceftriaxone Drug Therapy Combination Female Fluoroquinolones HIV Infections Hospitals Humans Logistic Models Male Middle Aged Multilocus Sequence Typing Multivariate Analysis Retrospective Studies Salmonella Infections Salmonella enterica Serogroup Sex Factors Trimethoprim Sulfamethoxazole Drug Combination Typhoid Fever Vietnam
Metallothionein-I/II expression associates with the astrocyte DNA damage response and not Alzheimer-type pathology in the ageing brain
CEG Brayne, Rachel Waller, Mark Murphy, Claire J Garwood, Luke Jennings, Paul R Heath, Annabelle Chambers, Fiona E Matthews, Paul G Ince, Stephen B Wharton, Julie E Simpson
Oct 04, 2018
Oxidative stress and oxidative DNA damage are early features of mild cognitive impairment and Alzheimer’s disease (AD), occurring before the formation of classical AD neuropathology, and resulting from an imbalance between pro-...
Coordination Cages Selectively Transport Molecular Cargoes Across Liquid Membranes.
Bao-Nguyen T Nguyen, John D Thoburn, Angela B Grommet, Duncan J Howe, Tanya K Ronson, Hugh P Ryan, Jeanne L Bolliger, Jonathan R Nitschke
Sep 02, 2021
Chemical purifications are critical processes across many industries, requiring 10-15% of humanity's global energy budget. Coordination cages are able to catch and release guest molecules based upon their size and shape...
Published by: Journal of the American Chemical Society
Antigenic characterization of highly pathogenic avian influenza A(H5N1) viruses with chicken and ferret antisera reveals clade-dependent variation in hemagglutination inhibition profiles.
Diep Thi Nguyen, Samuel S Shepard, David Francis Burke, Joyce Jones, Sharmi Thor, Long Van Nguyen, Tho Dang Nguyen, Amanda Balish, Dang Nguyen Hoang, Thanh Long To, Munir Iqbal, David E Wentworth, Erica Spackman, H Rogier van Doorn, C Todd Davis, Juliet E Bryant
Oct 10, 2018
Highly pathogenic avian influenza (HPAI) A(H5N1) viruses pose a significant economic burden to the poultry industry worldwide and have pandemic potential. Poultry vaccination against HPAI A(H5N1) viruses has been an important...
Mytilus trossulus introgression and consequences for shell traits in longline cultivated mussels.
Kati Michalek, David LJ Vendrami, Michaël Bekaert, David H Green, Kim S Last, Luca Telesca, Thomas A Wilding, Joseph I Hoffman
Aug 26, 2021
Mussels belonging to the Mytilus species complex (M. edulis, ME; M. galloprovincialis, MG; and M. trossulus, MT) often occur in sympatry, facilitating introgressive hybridization. This may be further promoted by mussel...
Perceptions of Machine Translation and Computer-Aided Translation by Professionals and the General Public
This article examines perceptions of MT and CAT among translation professionals and the general public by surveying 124 articles published in the professional journals of ITI Bulletin and MultiLingual and in the Chinese media...
Published by: IGI Global Scientific Publishing
Pathogenic variants in glutamyl-tRNAGln amidotransferase subunits cause a lethal mitochondrial cardiomyopathy disorder.
Marisa W Friederich, Sharita Timal, Christopher A Powell, Cristina Dallabona, Alina Kurolap, Sara Palacios-Zambrano, Drago Bratkovic, Terry GJ Derks, David Bick, Katelijne Bouman, Kathryn C Chatfield, Nadine Damouny-Naoum, Megan K Dishop, Tzipora C Falik-Zaccai, Fuad Fares, Ayalla Fedida, Ileana Ferrero, Renata C Gallagher, Rafael Garesse, Micol Gilberti, Cristina González, Katherine Gowan, Clair Habib, Rebecca K Halligan, Limor Kalfon, Kaz Knight, Dirk Lefeber, Laura Mamblona, Hanna Mandel, Adi Mory, John Ottoson, Tamar Paperna, Ger JM Pruijn, Pedro F Rebelo-Guiomar, Ann Saada, Bruno Sainz, Hayley Salvemini, Mirthe H Schoots, Jan A Smeitink, Maciej J Szukszto, Hendrik J Ter Horst, Frans van den Brandt, Francjan J van Spronsen, Joris A Veltman, Eric Wartchow, Liesbeth T Wintjes, Yaniv Zohar, Miguel A Fernández-Moreno, Hagit N Baris, Claudia Donnini, Michal Minczuk, Richard J Rodenburg, Johan LK Van Hove
Dec 07, 2018
Mitochondrial protein synthesis requires charging mt-tRNAs with their cognate amino acids by mitochondrial aminoacyl-tRNA synthetases, with the exception of glutaminyl mt-tRNA (mt-tRNAGln). mt-tRNAGln is indirectly charged by a...
Amino Acid Sequence Cardiomyopathies Female FIBROBLASTS Humans Infant Infant Newborn Lentivirus Male Mitochondrial Diseases Models Molecular Mutation Myocardium Nitrogenous Group Transferases Oxidative Phosphorylation Pedigree Protein Biosynthesis Protein Subunits RNA Transfer Saccharomyces cerevisiae
Mytilus trossulus introgression and consequences for shell traits in longline cultivated mussels
Kati Michalek, David L. J. Vendrami, Michaël Bekaert, David H. Green, Kim S. Last, Luca Telesca, Thomas A. Wilding, Joseph I. Hoffman
May 11, 2021
Abstract: Mussels belonging to the Mytilus species complex (M. edulis, ME; M. galloprovincialis, MG; and M. trossulus, MT) often occur in sympatry, facilitating introgressive hybridization. This may be further promoted by mussel...
Original Article Original Articles geometric morphometrics introgressive hybridization Me15/16 Mytilus edulis species complex shellfish aquaculture single nucleotide polymorphism
Published by: Evolutionary Applications
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