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Cover Image for Antibiotic resistance in bacteria associated with equine respiratory disease in the United Kingdom. View Article
Antibiotic resistance in bacteria associated with equine respiratory disease in the United Kingdom.
Joana D Fonseca, Daphne E Mavrides, Alice L Morgan, Jea G Na, Peter A Graham, Timothy D McHugh
May 25, 2020
INTRODUCTION: Respiratory diseases account for the highest number of clinical problems in horses compared with other body systems. While microbiological culture and sensitivity testing is essential for certain cases, knowledge...
antimicrobials equine resistance respiratory disease Animals Anti-Bacterial Agents Bacteria Drug Resistance Bacterial Female Horse Diseases Horses Male Respiratory Tract Diseases Retrospective Studies United Kingdom
Cover Image for Antimicrobial resistance profiles of bacteria associated with lower respiratory tract infections in cats and dogs in England. View Article
Antimicrobial resistance profiles of bacteria associated with lower respiratory tract infections in cats and dogs in England.
Daphne E Mavrides, Alice L Morgan, Jea G Na, Peter A Graham, Timothy D McHugh
Aug 11, 2021
BACKGROUND: Bacterial lower respiratory tract infections (bLRTIs) are common and potentially life threatening in cats and dogs. Antibiotic treatment is often initiated before the diagnosis of bLRTI; therefore improved knowledge...
Animals Anti-Bacterial Agents Anti-Infective Agents Bacteria Cat Diseases Cats Dog Diseases Dogs Drug Resistance Bacterial Escherichia coli Microbial Sensitivity Tests Respiratory Tract Infections Retrospective Studies
Cover Image for GPCR Activation of the G Protein-Gated Inward-Rectifier Potassium Channel View Article
GPCR Activation of the G Protein-Gated Inward-Rectifier Potassium Channel
Kouki Touhara
Jan 01, 0001
Heart rate is tightly regulated by the combined effects of the sympathetic and parasympathetic branches of the autonomic nervous system. These two branches control heart rate by stimulating different G protein-coupled receptors...
Life Sciences
Published by: Rockefeller University
Cover Image for Somatostatin secretion by Na+-dependent Ca2+-induced Ca2+ release in pancreatic delta-cells. View Article
Somatostatin secretion by Na+-dependent Ca2+-induced Ca2+ release in pancreatic delta-cells.
Elisa Vergari, Geoffrey Denwood, Albert Salehi, Quan Zhang, Julie Adam, Ahmed Alrifaiy, Ingrid Wernstedt Asterholm, Anna Benrick, Margarita V Chibalina, Lena Eliasson, Claudia Guida, Thomas G Hill, Alexander Hamilton, Reshma Ramracheya, Frank Reimann, Nils JG Rorsman, Ioannis Spilliotis, Andrei I Tarasov, Jonathan N Walker, Patrik Rorsman, Linford JB Briant
Jan 23, 2020
Pancreatic islets are complex micro-organs consisting of at least three different cell types: glucagon-secreting α-, insulin-producing β- and somatostatin-releasing δ-cells1. Somatostatin is a powerful paracrine inhibitor of...
Animals Calcium Diabetes mellitus Type 2 Glucagon Glucose Humans Hypoglycemia Insulin Mice sodium Somatostatin Somatostatin-Secreting Cells
Cover Image for Controlling Al–M Interactions in Group 1 Metal Aluminyls (M = Li, Na, and K). Facile Conversion of Dimers to Monomeric and Separated Ion Pairs View Article
Controlling Al–M Interactions in Group 1 Metal Aluminyls (M = Li, Na, and K). Facile Conversion of Dimers to Monomeric and Separated Ion Pairs
Matthew J. Evans, Mathew Anker, Michael G. Gardiner, Claire McMullin, Martyn Coles
Dec 06, 2021
The aluminyl compounds [M{Al(NONDipp)}]2 (NONDipp = [O(SiMe2NDipp)2]2–, Dipp = 2,6-iPr2C6H3), which exist as contacted dimeric pairs in both the solution and solid states, have been converted to monomeric ion pairs and separated...
Cover Image for G-Force PD View Article
G-Force PD
Roger A Barker, Lorenz Studer, Elena Cattaneo, Jun Takahashi, G-Force PD consortium
Aug 20, 2015
G-Force PD consortium
Cover Image for Structural Origins of Voltage Hysteresis in the Na-Ion Cathode P2-Na<sub>0.67</sub>[Mg<sub>0.28</sub>Mn<sub>0.72</sub>]O<sub>2</sub> View Article
Structural Origins of Voltage Hysteresis in the Na-Ion Cathode P2-Na<sub>0.67</sub>[Mg<sub>0.28</sub>Mn<sub>0.72</sub>]O<sub>2</sub>
Euan N Bassey, Philip J Reeves, Michael A Jones, Jeongjae Lee, Ieuan D Seymour, Giannantonio Cibin, Clare P Grey
Aug 26, 2021
P2-layered sodium-ion battery (NIB) cathodes are a promising class of Na-ion electrode materials with high Na+ mobility and relatively high capacities. In this work, we report the structural changes that take place in...
Published by: Chemistry of materials : a publication of the American Chemical Society
Cover Image for Controlling Al–M Interactions in Group 1 Metal Aluminyls (M = Li, Na, and K). Facile Conversion of Dimers to Monomeric and Separated Ion Pairs View Article
Controlling Al–M Interactions in Group 1 Metal Aluminyls (M = Li, Na, and K). Facile Conversion of Dimers to Monomeric and Separated Ion Pairs
Matthew J. Evans, Mathew Anker, Michael G. Gardiner, Claire McMullin, Martyn Coles
Dec 06, 2021
The aluminyl compounds [M{Al(NONDipp)}]2 (NONDipp = [O(SiMe2NDipp)2]2–, Dipp = 2,6-iPr2C6H3), which exist as contacted dimeric pairs in both the solution and solid states, have been converted to monomeric ion pairs and separated...
Cover Image for G-Quadruplexes View Article
G-Quadruplexes
Chun Kit Kwok, Catherine J Merrick
Mar 18, 2019
Guanine (G)-rich sequences in nucleic acids can assemble into G-quadruplex structures that involve G-quartets linked by loop nucleotides. The structural and topological diversity of G-quadruplexes have attracted great attention...
G-quadruplex aptamer biosensing cell imaging next-generation sequencing nucleic acid structure Animals Biomedical Research Biosensing Techniques G-Quadruplexes Humans
Cover Image for Synthesis of Novel Regenerable 13X Zeolite-Polyimide Adsorbent Foams View Article
Synthesis of Novel Regenerable 13X Zeolite-Polyimide Adsorbent Foams
Ramya G, Barry Crittenden, Martin Smith, Olivier Camus, Yong-Min Chew, Semali Perera
Apr 01, 2019

A new generic synthesis method is presented for the production of a polyimide (PI)/adsorbent (80 wt% 13X zeolite) regenerable foam filter. The method uses a dual parallel reaction foaming process comprising CO 2...

Adsorbent foam Adsorption Air Filters Isotherms modelling Polyimide
Cover Image for Synthesis of Novel Regenerable 13X Zeolite-Polyimide Adsorbent Foams View Article
Synthesis of Novel Regenerable 13X Zeolite-Polyimide Adsorbent Foams
Ramya G, Barry Crittenden, Martin Smith, Olivier Camus, Yong-Min Chew, Semali Perera
Apr 01, 2019

A new generic synthesis method is presented for the production of a polyimide (PI)/adsorbent (80 wt% 13X zeolite) regenerable foam filter. The method uses a dual parallel reaction foaming process comprising CO 2...

Adsorbent foam Adsorption Air Filters Isotherms modelling Polyimide
Cover Image for Remote stereocontrol in [3,3]-sigmatropic rearrangements View Article
Remote stereocontrol in [3,3]-sigmatropic rearrangements
Nathan W G Fairhurst, Mary F Mahon, R H Munday, David R Carbery
Feb 03, 2012
The Ireland - Claisen [3,3]-sigmatropic rearrangement has been used to access biologically important β,β′-dihydroxy α-amino acids. The rearrangement reported is highly stereoselective and offers excellent levels of remote...
Cover Image for RNA promotes phase separation of glycolysis enzymes into yeast G bodies in hypoxia. View Article
RNA promotes phase separation of glycolysis enzymes into yeast G bodies in hypoxia.
Gregory G Fuller, Ting Han, Mallory A Freeberg, James J Moresco, Amirhossein Ghanbari Niaki, Nathan P Roach, John R Yates, Sua Myong, John K Kim
Apr 17, 2020
In hypoxic stress conditions, glycolysis enzymes assemble into singular cytoplasmic granules called glycolytic (G) bodies. G body formation in yeast correlates with increased glucose consumption and cell survival. However, the...
RNA S. cerevisiae Cell Biology Glycolysis Hypoxia phase separation Cytoplasmic Granules Endoribonucleases Glycolysis RNA Fungal Saccharomyces cerevisiae Saccharomyces cerevisiae Proteins
Cover Image for Modelling and simulation of biased agonism dynamics at a G protein-coupled receptor. View Article
Modelling and simulation of biased agonism dynamics at a G protein-coupled receptor.
LJ Bridge, J Mead, E Frattini, I Winfield, G Ladds
Mar 16, 2018
Theoretical models of G protein-coupled receptor (GPCR) concentration-response relationships often assume an agonist producing a single functional response via a single active state of the receptor. These models have largely...
Biased signalling G protein-coupled receptors Mathematical pharmacology ordinary differential equations Receptor theory Algorithms Animals GTP-Binding Proteins Humans Ligands Models Biological Receptors G-Protein-Coupled Signal Transduction
Cover Image for Remote stereocontrol in [3,3]-sigmatropic rearrangements View Article
Remote stereocontrol in [3,3]-sigmatropic rearrangements
Nathan W G Fairhurst, Mary F Mahon, R H Munday, David R Carbery
Feb 03, 2012
The Ireland - Claisen [3,3]-sigmatropic rearrangement has been used to access biologically important β,β′-dihydroxy α-amino acids. The rearrangement reported is highly stereoselective and offers excellent levels of remote...
Cover Image for A Na+ conducting hydrogel for protection of organic electrochemical transistors. View Article
A Na+ conducting hydrogel for protection of organic electrochemical transistors.
I Del Agua, L Porcarelli, VF Curto, A Sanchez-Sanchez, E Ismailova, GG Malliaras, D Mecerreyes
Jul 18, 2018
Organic electrochemical transistors (OECTs) are being intensively developed for applications in electronics and biological interfacing. These devices rely on ions injected in a polymer film from an aqueous liquid electrolyte for...
Cover Image for The Construction of Sodium Alginate/Carboxymethyl Chitosan Microcapsules as the Physical Barrier to Reduce Corn Starch Digestion View Article
The Construction of Sodium Alginate/Carboxymethyl Chitosan Microcapsules as the Physical Barrier to Reduce Corn Starch Digestion
Linjie Zhan, Zhiwei Lin, Weixian Li, Yang Qin, Qingjie Sun, Na Ji, Fengwei Xie
May 31, 2024

To enhance the resistant starch (RS) content of corn starch, in this work, carboxymethyl chitosan/corn starch/sodium alginate microcapsules (CMCS/CS/SA) with varying concentrations of SA in a citric acid (CA) solution were...

carboxymethyl chitosan Citric Acid resistant starch Sodium Alginate
Cover Image for NKAINs: A Novel Family of Membrane Proteins that Interact with the Na, K-ATPase and Affect Membrane Excitability View Article
NKAINs: A Novel Family of Membrane Proteins that Interact with the Na, K-ATPase and Affect Membrane Excitability
Svetlana Gorokhova
Jan 01, 0001
A novel family of Na,K-ATPase interacting (NKAIN) proteins was cloned and characterized. These proteins are highly conserved across species and do not resemble any known proteins in the genome. Aside from the conserved...
NKAIN proteins drosophila NKAIN Neuronal function membrane excitability Life Sciences
Published by: Rockefeller University
Cover Image for Mechanochemical synthesis and ion transport properties of Na<sub>3</sub>OX (X = Cl, Br, I and BH<sub>4</sub>) antiperovskite solid electrolytes View Article
Mechanochemical synthesis and ion transport properties of Na<sub>3</sub>OX (X = Cl, Br, I and BH<sub>4</sub>) antiperovskite solid electrolytes
Ernest Ahiavi, James A. Dawson, Ulas Kudu, Matthieu Courty, M. Saiful Islam, Oliver Clemens, Christian Masquelier, Theodosios Famprikis
Sep 30, 2020

The push towards the development of next-generation solid-state batteries has motivated the search for novel solid electrolyte materials. Sodium antiperovskites represent a structural family of ion conductors that has emerged...

Antiperovskite Ball-milling Borohydride Ionic conductivity Molecular dynamics Synthesis
Cover Image for Mechanochemical synthesis and ion transport properties of Na<sub>3</sub>OX (X = Cl, Br, I and BH<sub>4</sub>) antiperovskite solid electrolytes View Article
Mechanochemical synthesis and ion transport properties of Na<sub>3</sub>OX (X = Cl, Br, I and BH<sub>4</sub>) antiperovskite solid electrolytes
Ernest Ahiavi, James A. Dawson, Ulas Kudu, Matthieu Courty, M. Saiful Islam, Oliver Clemens, Christian Masquelier, Theodosios Famprikis
Sep 30, 2020

The push towards the development of next-generation solid-state batteries has motivated the search for novel solid electrolyte materials. Sodium antiperovskites represent a structural family of ion conductors that has emerged...

Antiperovskite Ball-milling Borohydride Ionic conductivity Molecular dynamics Synthesis
Cover Image for Amino-Acid-Derived Naphthalenediimides as Versatile G-Quadruplex Binders View Article
Amino-Acid-Derived Naphthalenediimides as Versatile G-Quadruplex Binders
Dora-Maria Rasadean, Bin Sheng, Jyotirmayee Dash, G. Dan Pantos
Jun 23, 2017

The design and synthesis of water soluble, amino-acid-functionalised naphthalenediimides (NDIs) as potential ligands of native G-quadruplexes is reported. The NDIs were tested on a panel of oncogene promoters, on the human...

Circular dichroism DNA G-quadruplex naphthalenediimide structure–activity relationships
Cover Image for Amino-Acid-Derived Naphthalenediimides as Versatile G-Quadruplex Binders View Article
Amino-Acid-Derived Naphthalenediimides as Versatile G-Quadruplex Binders
Dora-Maria Rasadean, Bin Sheng, Jyotirmayee Dash, G. Dan Pantos
Jun 23, 2017

The design and synthesis of water soluble, amino-acid-functionalised naphthalenediimides (NDIs) as potential ligands of native G-quadruplexes is reported. The NDIs were tested on a panel of oncogene promoters, on the human...

Circular dichroism DNA G-quadruplex naphthalenediimide structure–activity relationships
Cover Image for Regulation of erythrocyte Na+/K+/2Cl- cotransport by an oxygen-switched kinase cascade. View Article
Regulation of erythrocyte Na+/K+/2Cl- cotransport by an oxygen-switched kinase cascade.
Suilan Zheng, Nathan A Krump, Mary M McKenna, Yen-Hsing Li, Anke Hannemann, Lisa J Garrett, John S Gibson, David M Bodine, Philip S Low
Feb 01, 2019
Many erythrocyte processes and pathways, including glycolysis, the pentose phosphate pathway (PPP), KCl cotransport, ATP release, Na+/K+-ATPase activity, ankyrin-band 3 interactions, and nitric oxide (NO) release, are regulated...
Na-K-Cl cotransporter (NKCC) O2 regulation of cation transport OSR1 SLC4A1 WNK1 band 3-deoxyhemoglobin interactions erythrocyte Hemoglobin protein phosphorylation Protein-Protein Interaction Animals Anion Exchange Protein 1 Erythrocyte Erythrocytes Hemoglobins Mice Phosphorylation Protein Serine-Threonine Kinases Solute Carrier Family 12 Member 2 WNK Lysine-Deficient Protein Kinase 1
Cover Image for The Construction of Sodium Alginate/Carboxymethyl Chitosan Microcapsules as the Physical Barrier to Reduce Corn Starch Digestion View Article
The Construction of Sodium Alginate/Carboxymethyl Chitosan Microcapsules as the Physical Barrier to Reduce Corn Starch Digestion
Linjie Zhan, Zhiwei Lin, Weixian Li, Yang Qin, Qingjie Sun, Na Ji, Fengwei Xie
May 31, 2024

To enhance the resistant starch (RS) content of corn starch, in this work, carboxymethyl chitosan/corn starch/sodium alginate microcapsules (CMCS/CS/SA) with varying concentrations of SA in a citric acid (CA) solution were...

carboxymethyl chitosan Citric Acid resistant starch Sodium Alginate
Cover Image for A practical graphitic carbon nitride (g-C<sub>3</sub>N<sub>4</sub>)based fluorescence sensor for the competitive detection of trithiocyanuric acid and mercury ions View Article
A practical graphitic carbon nitride (g-C<sub>3</sub>N<sub>4</sub>)based fluorescence sensor for the competitive detection of trithiocyanuric acid and mercury ions
Meng Li, Bo Wang, Xufei An, Zhiyong Li, Hongtao Zhu, Boyang Mao, David G. Calatayud, Tony D. James
Nov 01, 2019

A fluorescent sensor for the detection of trithiocyanuric acid (TCA)and Hg2+ was developed based on competitive interactions: non-covalent stacking between g-C3N4 and TCA vs coordinative...

Dye sensor Fluorescent sensor functional materials graphitic carbon nitride Mercury sensing

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