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A scalable insect cell-based production process of the human recombinant BMX for in-vitro covalent ligand high-throughput screening.
Bone Marrow Tyrosine kinase in the chromosome X (BMX) is a TEC family kinase associated with numerous pathological pathways in cancer cells. Covalent inhibition of BMX activity holds promise as a therapeutic approach against...
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Physiological demands of a swimming-based video game

Active video games (exergames) may provide short-term increase in energy expenditure. We explored the effects of gender and prior experience on aerobic and anaerobic energy systems contributions, and the activity profiles of...

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Efficiency and Equity in the Spatial Planning of Primary Schools
The shrinking populations of many regions in Portugal have led to a debate on the criteria which should guide the restructuring of public services at the local scale, and namely how to balance raising per capita costs with...
Physiological demands of a swimming-based video game

Active video games (exergames) may provide short-term increase in energy expenditure. We explored the effects of gender and prior experience on aerobic and anaerobic energy systems contributions, and the activity profiles of...

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Testicular organoids
BACKGROUND: In recent decades, a broad range of strategies have been applied to model the testicular microenvironment in vitro. These models have been utilized to study testicular physiology and development. However, a system...
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Does exergaming drive future physical activity and sport intentions?

We studied how usability and playability of sport exergames affect future intentions of participation in physical activity or actual sport. We employed questionnaires to measure participants’ enjoyment, usability...

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Does exergaming drive future physical activity and sport intentions?

We studied how usability and playability of sport exergames affect future intentions of participation in physical activity or actual sport. We employed questionnaires to measure participants’ enjoyment, usability...

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Prospective association between adherence to the Mediterranean diet and hepatic steatosis
Objective: The Mediterranean diet has been promoted as a healthy dietary pattern, but whether the Mediterranean diet may help to prevent hepatic steatosis is not clear. This study aimed to evaluate the prospective association...
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Muscle activation behavior in a swimming exergame

The effects of playing intensity and prior exergame and sport experience on the activation patterns of upper limb muscles during a swimming exergame were investigated. Surface electromyography of Biceps Brachii, Triceps...

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Self-organising human gonads generated by a Matrigel-based gradient system.
BACKGROUND: Advances in three-dimensional culture technologies have led to progression in systems used to model the gonadal microenvironment in vitro. Despite demonstrating basic functionality, tissue organisation is often...
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Muscle activation behavior in a swimming exergame

The effects of playing intensity and prior exergame and sport experience on the activation patterns of upper limb muscles during a swimming exergame were investigated. Surface electromyography of Biceps Brachii, Triceps...

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Principles for Engineering Social Interaction in Asynchronous Mobile Games
Since their first appearance, mobile devices have had exponential technological growth and have gained other functionalities besides standard calls and messaging services. With the advent of smartphones, the mobile gaming market...
Winter is coming
The preservative effects of low temperature on biological materials have been long recognised, and cryopreservation is now widely used in biomedicine, including in organ transplantation, regenerative medicine and drug discovery....
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