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Results: 37
Dual Mode Sensing of Binding and Blocking of Cancer Exosomes to Biomimetic Human Primary Stem Cell Surfaces.
Johana Uribe, Walther C Traberg, Adel Hama, Victor Druet, Zeinab Mohamed, Amanda Ooi, Anna-Maria Pappa, Miriam Huerta, Sahika Inal, Róisín M Owens, Susan Daniel
Nov 24, 2021
Exposure of the HIV-1 broadly neutralizing antibody 10E8 MPER epitope on the membrane surface by gp41 transmembrane domain scaffolds
Victoria Oakes, Johana Torralba, Edurne Rujas, José L Nieva, Carmen Domene, Beatriz Apellaniz
Jun 01, 2018
The 10E8 antibody achieves near-pan neutralization of HIV-1 by targeting the remarkably conserved gp41 membrane-proximal external region (MPER) and the connected transmembrane domain (TMD) of the HIV-1 envelope glycoprotein...
AIDS Vaccines Amino Acid Sequence Antibodies Neutralizing/immunology Antigen-Antibody Reactions Antigens Surface/chemistry Epitopes/immunology HIV Antibodies/immunology HIV Envelope Protein gp41/chemistry HIV-1/immunology Humans Liposomes Models Molecular Molecular Dynamics Simulation Peptide Fragments/immunology Protein Conformation Protein Domains /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Exposure of the HIV-1 broadly neutralizing antibody 10E8 MPER epitope on the membrane surface by gp41 transmembrane domain scaffolds
Victoria Oakes, Johana Torralba, Edurne Rujas, José L Nieva, Carmen Domene, Beatriz Apellaniz
Jun 01, 2018
The 10E8 antibody achieves near-pan neutralization of HIV-1 by targeting the remarkably conserved gp41 membrane-proximal external region (MPER) and the connected transmembrane domain (TMD) of the HIV-1 envelope glycoprotein...
AIDS Vaccines Amino Acid Sequence Antibodies Neutralizing/immunology Antigen-Antibody Reactions Antigens Surface/chemistry Epitopes/immunology HIV Antibodies/immunology HIV Envelope Protein gp41/chemistry HIV-1/immunology Humans Liposomes Models Molecular Molecular Dynamics Simulation Peptide Fragments/immunology Protein Conformation Protein Domains /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Random walks with preferential relocations and fading memory
Consider a stochastic process that behaves as a d-dimensional simple and symmetric random walk, except that, with a certain fixed probability, at each step, it chooses instead to jump to a given site with probability...
Inhibitory effects of orthosilicic acid on osteoclastogenesis in RANKL-stimulated RAW264.7 cells.
Catarina Magnusson, Pamela Uribe, Ravin Jugdaohsingh, Jonathan J Powell, Anders Johansson, Maria Ransjö
Aug 17, 2021
Random walks with preferential relocations and fading memory
Consider a stochastic process that behaves as a d-dimensional simple and symmetric random walk, except that, with a certain fixed probability, at each step, it chooses instead to jump to a given site with probability...
Apc Min/+ tumours and normal mouse small intestines show linear metabolite concentration and DNA cytosine hydroxymethylation gradients from pylorus to colon
Abstract: Topographical variations of metabolite concentrations have been reported in the duodenum, jejunum and ileum of the small intestine, and in human intestinal tumours from those regions, but there are no published...
Apc Min/+ tumours and normal mouse small intestines show linear metabolite concentration and DNA cytosine hydroxymethylation gradients from pylorus to colon
Abstract: Topographical variations of metabolite concentrations have been reported in the duodenum, jejunum and ileum of the small intestine, and in human intestinal tumours from those regions, but there are no published...
The action of β-hydroxybutyrate on the growth, metabolism and global histone H3 acetylation of spontaneous mouse mammary tumours
WarpPINN
Pablo Arratia López, Hernán Mella, Sergio Uribe, Daniel E. Hurtado, Francisco Sahli Costabal
Oct 31, 2023
The diagnosis of heart failure usually includes a global functional assessment, such as ejection fraction measured by magnetic resonance imaging. However, these metrics have low discriminate power to distinguish different...
Cardiac mechanics Cardiac strain image registration physics-informed neural networks /dk/atira/pure/subjectarea/asjc/3600/3614 name=Radiological and Ultrasound Technology /dk/atira/pure/subjectarea/asjc/2700/2741 name=Radiology Nuclear Medicine and imaging /dk/atira/pure/subjectarea/asjc/1700/1707 name=Computer Vision and Pattern Recognition /dk/atira/pure/subjectarea/asjc/2700/2718 name=Health Informatics /dk/atira/pure/subjectarea/asjc/1700/1704 name=Computer Graphics and Computer-Aided Design
ApcMin/+ tumours and normal mouse small intestines show linear metabolite concentration and DNA cytosine hydroxymethylation gradients from pylorus to colon.
The action of β-hydroxybutyrate on the growth, metabolism and global histone H3 acetylation of spontaneous mouse mammary tumours
Loreta M Rodrigues, Santiago Uribe-Lewis, Basetti Madhu, Davina J Honess, Marion Stubbs, John R Griffiths
May 05, 2017
Abstract
Background
Ketone bodies have both metabolic and epigenetic roles in cancer. In several studies, they showed an anti-cancer effect via inhibition of histone deacetylases;...
Soluble silica stimulates osteogenic differentiation and gap junction communication in human dental follicle cells
Pamela Uribe, Anders Johansson, Ravin Jugdaohsingh, Jonathan J. Powell, Catarina Magnusson, Marcela Davila, Anna Westerlund, Maria Ransjö
Jun 18, 2020
Abstract: Several studies have indicated that dietary silicon (Si) is beneficial for bone homeostasis and skeletal health. Furthermore, Si-containing bioactive glass biomaterials have positive effects on bone regeneration when...
5-hydroxymethylcytosine and gene activity in mouse intestinal differentiation.
Santiago Uribe-Lewis, Thomas Carroll, Suraj Menon, Anna Nicholson, Piotr J Manasterski, Douglas J Winton, Simon J A Buczacki, Adele Murrell
Feb 19, 2020
Cytosine hydroxymethylation (5hmC) in mammalian DNA is the product of oxidation of methylated cytosines (5mC) by Ten-Eleven-Translocation (TET) enzymes. While it has been shown that the TETs influence 5mC metabolism...
Published by: Scientific reports
Genome diversification within a clonal population of pandemic <i>Vibrio parahaemolyticus </i>seems to depend on the life circumstances of each individual bacteria
David E Loyola, Cristell Navarro, Paulina Uribe, Katherine García, Claudia Mella, Diego Díaz, Natalia Valdes, Jaime Martínez-Urtaza, Romilio T Espejo
Mar 15, 2015
BACKGROUND: New strains of Vibrio parahaemolyticus that cause diarrhea in humans by seafood ingestion periodically emerge through continuous evolution in the ocean. Influx and expansion in the Southern Chilean ocean of a...
The molecular basis for stability of heterochromatin-mediated silencing in mammals.
Kyoko Hiragami-Hamada, Sheila Q Xie, Alexander Saveliev, Santiago Uribe-Lewis, Ana Pombo, Richard Festenstein
Jun 16, 2011
5-hydroxymethylcytosine and gene activity in mouse intestinal differentiation
Santiago Uribe-Lewis, Thomas Carroll, Suraj Menon, Anna Nicholson, Piotr J. Manasterski, Douglas J. Winton, Simon J. A. Buczacki, Adele Murrell
Jan 16, 2021
Abstract: Cytosine hydroxymethylation (5hmC) in mammalian DNA is the product of oxidation of methylated cytosines (5mC) by Ten-Eleven-Translocation (TET) enzymes. While it has been shown that the TETs influence 5mC metabolism...
5-Hydroxymethylcytosine is a predominantly stable DNA modification.
Martin Bachman, Santiago Uribe-Lewis, Xiaoping Yang, Michael Williams, Adele Murrell, Shankar Balasubramanian
Sep 30, 2014
WarpPINN
Pablo Arratia López, Hernán Mella, Sergio Uribe, Daniel E. Hurtado, Francisco Sahli Costabal
Oct 31, 2023
The diagnosis of heart failure usually includes a global functional assessment, such as ejection fraction measured by magnetic resonance imaging. However, these metrics have low discriminate power to distinguish different...
Cardiac mechanics Cardiac strain image registration physics-informed neural networks /dk/atira/pure/subjectarea/asjc/3600/3614 name=Radiological and Ultrasound Technology /dk/atira/pure/subjectarea/asjc/2700/2741 name=Radiology Nuclear Medicine and imaging /dk/atira/pure/subjectarea/asjc/1700/1707 name=Computer Vision and Pattern Recognition /dk/atira/pure/subjectarea/asjc/2700/2718 name=Health Informatics /dk/atira/pure/subjectarea/asjc/1700/1704 name=Computer Graphics and Computer-Aided Design
A Multiallelic Molecular Beacon-Based Real-Time RT-PCR Assay for the Detection of SARS-CoV-2.
5-Formylcytosine can be a stable DNA modification in mammals
Martin Bachman, Santiago Uribe-Lewis, Xiaoping Yang, Heather E. Burgess, Mario Iurlaro, Wolf Reik, Adele Murrell, Shankar Balasubramanian
Aug 13, 2015
5-Formylcytosine (5fC) is a rare base found in mammalian DNA and thought to be involved in active DNA demethylation. Here, we show that developmental dynamics of 5fC levels in mouse DNA differ from those of...
5-Formylcytosine can be a stable DNA modification in mammals
Martin Bachman, Santiago Uribe-Lewis, Xiaoping Yang, Heather E. Burgess, Mario Iurlaro, Wolf Reik, Adele Murrell, Shankar Balasubramanian
Aug 13, 2015
5-Formylcytosine (5fC) is a rare base found in mammalian DNA and thought to be involved in active DNA demethylation. Here, we show that developmental dynamics of 5fC levels in mouse DNA differ from those of...
Soluble silica stimulates osteogenic differentiation and gap junction communication in human dental follicle cells.
Pamela Uribe, Anders Johansson, Ravin Jugdaohsingh, Jonathan J Powell, Catarina Magnusson, Marcela Davila, Anna Westerlund, Maria Ransjö
Jun 18, 2021
Several studies have indicated that dietary silicon (Si) is beneficial for bone homeostasis and skeletal health. Furthermore, Si-containing bioactive glass biomaterials have positive effects on bone regeneration when used for...
Context-Specific Effects of TGF-β/SMAD3 in Cancer Are Modulated by the Epigenome.
Ana Tufegdzic Vidakovic, Oscar M Rueda, Stephin J Vervoort, Ankita Sati Batra, Mae Akilina Goldgraben, Santiago Uribe-Lewis, Wendy Greenwood, Paul J Coffer, Alejandra Bruna, Carlos Caldas
Oct 21, 2015
Binding Sites Cell Line Tumor DNA DNA Methylation Epigenesis Genetic Histones Humans Neoplastic Stem Cells Promoter Regions Genetic Protein Binding RNA Interference RNA Small Interfering Signal Transduction Smad2 Protein Smad3 Protein Trans-Activators Transcription Factors Transforming Growth Factor beta
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