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Results: 107
Effective induction therapy for anti-SRP associated myositis in childhood
E L Binns, Elena Moraitis, S Maillard, S Tansley, N McHugh, Thomas S Jacques, L R Wedderburn, Clarissa Pilkington, S A Yasin, Kiran Nistala
Oct 31, 2017
BACKGROUND: Anti-Signal Recognition Particle associated myopathy is a clinically and histopathologically distinct subgroup of Juvenile Idiopathic Inflammatory Myositis, which is under-recognised in children and fails to...
Effective induction therapy for anti-SRP associated myositis in childhood
E L Binns, Elena Moraitis, S Maillard, S Tansley, N McHugh, Thomas S Jacques, L R Wedderburn, Clarissa Pilkington, S A Yasin, Kiran Nistala
Oct 31, 2017
BACKGROUND: Anti-Signal Recognition Particle associated myopathy is a clinically and histopathologically distinct subgroup of Juvenile Idiopathic Inflammatory Myositis, which is under-recognised in children and fails to...
Muscle biopsy in combination with myositis-specific autoantibodies aids prediction of outcomes in juvenile dermatomyositis
Claire T. Deakin, Shireena A. Yasin, Stefania Simou, Katie A. Arnold, Sarah L. Tansley, Zoe E. Betteridge, Neil J. McHugh, Hemlata Varsani, Janice L. Holton, Thomas S. Jacques, Clarissa A. Pilkington, Kiran Nistala, Lucy R. Wedderburn
Nov 01, 2016
Objective
Juvenile dermatomyositis (DM) is a rare and severe autoimmune condition characterized by rash and proximal muscle weakness. While some patients respond to standard treatment, others do not. This study was carried...
Juvenile dermatomyositis (DM) is a rare and severe autoimmune condition characterized by rash and proximal muscle weakness. While some patients respond to standard treatment, others do not. This study was carried...
Muscle biopsy in combination with myositis-specific autoantibodies aids prediction of outcomes in juvenile dermatomyositis
Claire T. Deakin, Shireena A. Yasin, Stefania Simou, Katie A. Arnold, Sarah L. Tansley, Zoe E. Betteridge, Neil J. McHugh, Hemlata Varsani, Janice L. Holton, Thomas S. Jacques, Clarissa A. Pilkington, Kiran Nistala, Lucy R. Wedderburn
Nov 01, 2016
Objective
Juvenile dermatomyositis (DM) is a rare and severe autoimmune condition characterized by rash and proximal muscle weakness. While some patients respond to standard treatment, others do not. This study was carried...
Juvenile dermatomyositis (DM) is a rare and severe autoimmune condition characterized by rash and proximal muscle weakness. While some patients respond to standard treatment, others do not. This study was carried...
Federal Cabinet of Pakistan
Naumana Kiran
Jun 30, 2023
The paper focuses on the Federal cabinet in two perspectives i.e. formation and stratification of the federal cabinet of Pakistan from the year 1988 to 1999. This period observed four elected governments with coalition set ups....
Appointment criteria Federal cabinet composition Inner cabinet Stratification History of Pakistan politics of Pakistan Institutions of Pakistan
Published by: Department of History, University of Karachi
Sol-gel preparation of Zn-V-Mn-O thin films for low voltage varistor applications
ZnO-based thin films in the Zn-V-Mn-O system have been synthesised by a sol-gel process and characterised for use in low voltage varistor applications. The films were prepared through multi-layer deposition of a precursor...
Nomenclature and Geography of Ancient Gandhara
Kiran Shahid Siddiqui
Dec 14, 2019
Gandhara has been a significant region since the early historic period of South Asia. Besides its emergenceand growth as an artistic and cultural center, the uniqueness of Gandhara lies in its location because it was connected...
Published by: Department of History, University of Karachi
How to facilitate critical action learning
Critical Action Learning (CAL) is a well-established approach to action learning. However, it has not necessarily been clear to action learning practitioners what makes CAL ‘critical’ and what are the implications in...
The Use of Effective Risk Management in Cloud Computing Projects
Usha Kiran Marichetty
Jan 01, 0001
Project management is one of the most important procedures that promote delivery of services. Examples of such projects include cloud computing projects. Despite the potential benefits associated with cloud computing projects...
Project Management cloud computing and risk management Management Information Systems Management Sciences and Quantitative Methods
Published by: Harrisburg University of Science and Technology
The Role of Educational Technology in Academia
The subject of study known as educational technology examines the process of examining, creating, developing, implementing, and evaluating the instructional environment, learning materials, students, and the learning process in...
Global Information Technology Computer Science and Information Technology Global Information Technology Physical Sciences and Engineering Business and Management
Published by: IGI Global Scientific Publishing
How to facilitate critical action learning
Critical Action Learning (CAL) is a well-established approach to action learning. However, it has not necessarily been clear to action learning practitioners what makes CAL ‘critical’ and what are the implications in...
Availability of Community-Based Mentoring Program for Children and Youth
Abstract
This study aimed to explore the availability of community-based mentoring programs for children and youth within the various communities including Bohri, Ismaili, Memon, Parsi, Christian, and Hindu in Karachi...
children development community-based programs Karachi-based communities mentoring programs youth development Education
Published by: Department of History, University of Karachi
Evolutionary programming as a platform for in silico metabolic engineering.
BACKGROUND: Through genetic engineering it is possible to introduce targeted genetic changes and hereby engineer the metabolism of microbial cells with the objective to obtain desirable phenotypes. However, owing to the...
Algorithms Benzaldehydes Computational Biology Computer Simulation Escherichia coli evolution Molecular Gene Expression Regulation Genetic Engineering Genome Fungal Glycerol Models Biological Models Genetic Phenotype Protein Engineering Protein Interaction Mapping Saccharomyces cerevisiae Software Succinic Acid
Towards a mechanistic understanding of reciprocal drug-microbiome interactions.
Broad-spectrum antibiotics target multiple gram-positive and gram-negative bacteria, and can collaterally damage the gut microbiota. Yet, our knowledge of the extent of damage, the antibiotic activity spectra, and the resistance...
Design of Compressor Endwall Velocity Triangles
The operating range of a compressor is usually limited by the rapid growth of three-dimensional (3D) separations in the endwall flow region. In contrast, the freestream region is not usually close to its diffusion limit...
Assessment of Knowledge and Attitude of Mothers Regarding Oral Health Care of Children from Birth to 5 Years through an Audiovisual Aid
Aim: The aim of the study was to assess the knowledge of mothers regarding Infant Oral health and dental education andto evaluate the effect of audiovisual aid for providing guidance on improving the knowledge and attitude of...
Published by: IJHS Medical Association
StAR-Related Lipid Transfer (START) Domains Across the Rice Pangenome Reveal How Ontogeny Recapitulated Selection Pressures During Rice Domestication.
The StAR-related lipid transfer (START) domain containing proteins or START proteins, encoded by a plant amplified family of evolutionary conserved genes, play important roles in lipid binding, transport, signaling, and...
Negative Poisson’s ratio polyethylene matrix and 0.5BaCa0.8Zr0.2O3-0.5Ba0.7Ca0.3TiO3 based piezocomposite for sensing and energy harvesting applications
Saptarshi Karmakar, Raj Kiran, Chris Bowen, Rahul Vaish, Vishal Singh Chauhan, Zainab Mufarreh Elqahtani, Samia Ben Ahmed, M. S. Al-Buriahi, Anuruddh Kumar, Tae Hyun Sung
Dec 30, 2022
Finite element studies were conducted on 0.5Ba(Zr0.2 Ti0.8) O3-0.5(Ba0.7 Ca0.3)TiO3 (BCZT) piezoelectric particles embedded in polyethylene matrix to create a piezocomposite having a positive and negative Poisson's ratio of...
CRISPRi screens reveal genes modulating yeast growth in lignocellulose hydrolysate
Friederike Gutmann, Cosimo Jann, Filipa Pereira, Andreas Johansson, Lars M. Steinmetz, Kiran R. Patil
Feb 10, 2021
Assessment of Knowledge and Attitude of Mothers Regarding Oral Health Care of Children from Birth to 5 Years through an Audiovisual Aid
Aim: The aim of the study was to assess the knowledge of mothers regarding Infant Oral health and dental education andto evaluate the effect of audiovisual aid for providing guidance on improving the knowledge and attitude of...
Published by: IJHS Medical Association
Consumers' Digital Wallet Adoption
This empirical study aims to examine what drives consumers' behavioral intention to adopt digital wallet by integrating task technology fit theory into UTAUT model. For this purpose, 700 samples were approached through emails...
Published by: IGI Global Scientific Publishing
Bioactivity assessment of natural compounds using machine learning models trained on target similarity between drugs.
Vinita Periwal, Stefan Bassler, Sergej Andrejev, Natalia Gabrielli, Kaustubh Raosaheb Patil, Athanasios Typas, Kiran Raosaheb Patil
May 26, 2022
Natural compounds constitute a rich resource of potential small molecule therapeutics. While experimental access to this resource is limited due to its vast diversity and difficulties in systematic purification, computational...
CRISPRi screens reveal genes modulating yeast growth in lignocellulose hydrolysate.
Friederike Gutmann, Cosimo Jann, Filipa Pereira, Andreas Johansson, Lars M Steinmetz, Kiran R Patil
Mar 26, 2021
BACKGROUND: Baker's yeast is a widely used eukaryotic cell factory, producing a diverse range of compounds including biofuels and fine chemicals. The use of lignocellulose as feedstock offers the opportunity to run these...
Unravelling metabolic cross-feeding in a yeast-bacteria community using 13 C-based proteomics.
Natalia Gabrielli, Christoniki Maga-Nteve, Eleni Kafkia, Mandy Rettel, Jakob Loeffler, Stephan Kamrad, Athanasios Typas, Kiran Raosaheb Patil
Feb 13, 2023
Cross-feeding is fundamental to the diversity and function of microbial communities. However, identification of cross-fed metabolites is often challenging due to the universality of metabolic and biosynthetic intermediates....
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