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Interactive effects of DRD2 rs6277 polymorphism, environment and sex on impulsivity in a population-representative study
Previous research has shown that dopaminergic dysregulation and early life stress interact to impact on aspects of impulse control. This study aimed to explore the potentially interactive effects of the rs6277 polymorphism of...
Ultrahigh-Throughput Detection of Enzymatic Alcohol Dehydrogenase Activity in Microfluidic Droplets with a Direct Fluorogenic Assay.
Miriam Klaus, Paul Jannis Zurek, Tomasz S Kaminski, Ahir Pushpanath, Katharina Neufeld, Florian Hollfelder
Oct 13, 2021
Sialylation acts as a checkpoint for innate immune responses in the central nervous system.
Sialic acids are monosaccharides that normally terminate the glycan chains of cell surface glyco-proteins and -lipids in mammals, and are highly enriched in the central nervous tissue. Sialic acids are conjugated to proteins and...
Using Customer Review Systems to Support Purchase Decisions
Online reviews have emerged as influential sources of information which greatly affect customers’ pre-purchase decision. Some studies have found that culture impacts online reviews, but many aspects of online review usage are...
Published by: IGI Global Scientific Publishing
Factors Influencing Intention to Use Online Consumer Reviews
Online consumer reviews have been shown to play an important role that can influence consumers' attitudes, behaviors, and purchasing decisions. This study seeks to understand factors that affect user intention to use online...
Published by: IGI Global Scientific Publishing
CACNA1C methylation
Kyla Pennington, Kristel Klaus, Helene A Fachim, Kevin Butler, Ksenia Trischel, Caroline F Dalton, Adrian Heald, Gavin P Reynolds
Nov 10, 2020
Aim: We investigated morning cortisol, stress, rs1006737 and childhood trauma relationship with CACNA1C methylation. Materials & methods: Morning cortisol release, childhood trauma and perceived stress were collected and...
Gedenkwort von 1991 für Ludwig Landgrebe
Klaus Held
Apr 27, 2021
Nach dem Tod von Ludwig Landgrebe am 14. August 1991 fand eine Wochespäter in seinem Wohnort Bergisch-Gladbach (nahe der Stadt Köln, an derenUniversität er gelehrt hatte) am 22. August ein Trauergottesdienst statt. DieFamilie...
Published by: Memorial University of Newfoundland
CACNA1C methylation
Kyla Pennington, Kristel Klaus, Helene A Fachim, Kevin Butler, Ksenia Trischel, Caroline F Dalton, Adrian Heald, Gavin P Reynolds
Dec 10, 2020
Aim: We investigated morning cortisol, stress, rs1006737 and childhood trauma relationship with CACNA1C methylation. Materials & methods: Morning cortisol release, childhood trauma and perceived stress were collected and...
A Comparative Study of Trust in Mobile Banking
With the rapid growth of mobile phone usage, mobile services have influenced many industries including banking. Mobile banking has become a popular service as it offers a convenient channel for customers to perform banking...
Published by: IGI Global Scientific Publishing
PI3Kδ promotes CD4(+) T-cell interactions with antigen-presenting cells by increasing LFA-1 binding to ICAM-1.
Activation of T lymphocytes by peptide/major histocompatibility complex on antigen-presenting cells (APCs) involves dynamic contacts between the two cells, during which T cells undergo marked morphological changes. These...
Actin Depolymerizing Factors Animals Antigen-Presenting Cells CD4-Positive T-Lymphocytes Cell Adhesion Cell Communication Cell Movement Cell Shape Class I Phosphatidylinositol 3-Kinases Dendritic Cells GTP-Binding Proteins Intercellular Adhesion Molecule-1 Lymph Nodes Lymphocyte Function-Associated Antigen-1 Mice Inbred C57BL Phosphatidylinositol 3-Kinases Protein Binding Proto-Oncogene Proteins c-akt Receptors Antigen T-Cell
Gedenkwort von 1991 für Ludwig Landgrebe
Klaus Held
Apr 27, 2021
Nach dem Tod von Ludwig Landgrebe am 14. August 1991 fand eine Wochespäter in seinem Wohnort Bergisch-Gladbach (nahe der Stadt Köln, an derenUniversität er gelehrt hatte) am 22. August ein Trauergottesdienst statt. DieFamilie...
Published by: Memorial University of Newfoundland
PI3K Signaling in Normal B Cells and Chronic Lymphocytic Leukemia (CLL).
B cells provide immunity to extracellular pathogens by secreting a diverse repertoire of antibodies with high affinity and specificity for exposed antigens. The B cell receptor (BCR) is a transmembrane antibody, which...
Constructing a distant future
We develop the concept of the distant future as a new way of seeing the future in collective efforts. While a near future is represented in practical terms and concerned with forming expectations and goals under conditions of...
/dk/atira/pure/subjectarea/asjc/1400/1403 name=Business and International Management /dk/atira/pure/subjectarea/asjc/1400/1400 name=General Business,Management and Accounting /dk/atira/pure/subjectarea/asjc/1400/1408 name=Strategy and Management /dk/atira/pure/subjectarea/asjc/1400/1405 name=Management of Technology and Innovation /dk/atira/pure/sustainabledevelopmentgoals/climate_action name=SDG 13 - Climate Action
Business groups' outward FDI
Outward FDI strategies are driven by firms' resource endowments, which in turn are conditioned by their home environment. In emerging economies, thus, the pattern of outward FDI is shaped by local firms' idiosyncratic contexts...
Constructing a distant future
We develop the concept of the distant future as a new way of seeing the future in collective efforts. While a near future is represented in practical terms and concerned with forming expectations and goals under conditions of...
/dk/atira/pure/subjectarea/asjc/1400/1403 name=Business and International Management /dk/atira/pure/subjectarea/asjc/1400/1400 name=General Business,Management and Accounting /dk/atira/pure/subjectarea/asjc/1400/1408 name=Strategy and Management /dk/atira/pure/subjectarea/asjc/1400/1405 name=Management of Technology and Innovation /dk/atira/pure/sustainabledevelopmentgoals/climate_action name=SDG 13 - Climate Action
The Therapeutic Potential for PI3K Inhibitors in Autoimmune Rheumatic Diseases.
The class 1 PI3Ks are lipid kinases with key roles in cell surface receptor-triggered signal transduction pathways. Two isoforms of the catalytic subunits, p110γ and p110δ, are enriched in leucocytes in which they promote...
Immune adaptor SKAP1 acts a scaffold for Polo-like kinase 1 (PLK1) for the optimal cell cycling of T-cells.
While the immune cell adaptor protein SKAP1 mediates LFA-1 activation induced by antigen-receptor (TCR/CD3) ligation on T-cells, it is unclear whether the adaptor interacts with other mediators of T-cell function. In this...
Phosphoinositide 3-kinase δ is a regulatory T-cell target in cancer immunotherapy.
Tumour infiltration by regulatory T (Treg) cells contributes to suppression of the anti-tumour immune response, which limits the efficacy of immune-mediated cancer therapies. The phosphoinositide 3-kinase (PI3K) pathway has key...
T cell Regulatory T cell Signal Transduction tumour immunology Animals Antineoplastic Agents Class Ib Phosphatidylinositol 3-Kinase Humans Immunotherapy Lymphocytes Tumor-Infiltrating Molecular Targeted Therapy Neoplasms Phenotype Protein Kinase Inhibitors Signal Transduction T-Lymphocytes Regulatory Tumor Escape Tumor Microenvironment
Distilling Authenticity
Authenticity is increasingly seen as a source of competitive advantage in many industries. Accordingly, authenticity work, the organizational efforts to develop and sustain believable authenticity claims, has emerged as an...
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