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Interview with Eugene 'Gene' Driver
Julius Eugene Driver
Jan 01, 0001
In his January 24, 2018 interview with Emily Deinert, Gene Driver discusses his career in the Air Force - he served during the Cold War and the Vietnam War. During the Cold War, he was loaned out to the CIA and worked in Area 51...
Published by: Winthrop University
Combined image and genomic analysis of high-grade serous ovarian cancer reveals PTEN loss as a common driver event and prognostic classifier.
Filipe C Martins, Ines de Santiago, Anne Trinh, Jian Xian, Anne Guo, Karen Sayal, Mercedes Jimenez-Linan, Suha Deen, Kristy Driver, Marie Mack, Jennifer Aslop, Paul D Pharoah, Florian Markowetz, James D Brenton
Mar 16, 2015
Ontology-based prediction of cancer driver genes.
Sara Althubaiti, Andreas Karwath, Ashraf Dallol, Adeeb Noor, Shadi Salem Alkhayyat, Rolina Alwassia, Katsuhiko Mineta, Takashi Gojobori, Andrew D Beggs, Paul N Schofield, Georgios V Gkoutos, Robert Hoehndorf
Nov 27, 2019
Identifying and distinguishing cancer driver genes among thousands of candidate mutations remains a major challenge. Accurate identification of driver genes and driver mutations is critical for advancing cancer research and...
Ontology-based prediction of cancer driver genes
Sara Althubaiti, Andreas Karwath, Ashraf Dallol, Adeeb Noor, Shadi Salem Alkhayyat, Rolina Alwassia, Katsuhiko Mineta, Takashi Gojobori, Andrew D. Beggs, Paul N. Schofield, Georgios V. Gkoutos, Robert Hoehndorf
Nov 21, 2020
Abstract: Identifying and distinguishing cancer driver genes among thousands of candidate mutations remains a major challenge. Accurate identification of driver genes and driver mutations is critical for advancing cancer...
Ontology-based prediction of cancer driver genes.
Sara Althubaiti, Andreas Karwath, Ashraf Dallol, Adeeb Noor, Shadi Salem Alkhayyat, Rolina Alwassia, Katsuhiko Mineta, Takashi Gojobori, Andrew D Beggs, Paul N Schofield, Georgios V Gkoutos, Robert Hoehndorf
Jan 03, 2020
Identifying and distinguishing cancer driver genes among thousands of candidate mutations remains a major challenge. Accurate identification of driver genes and driver mutations is critical for advancing cancer research and...
Familial relative risks for breast cancer by pathological subtype
Nasim Mavaddat, Paul D Pharoah, Fiona Blows, Kristy E Driver, Elena Provenzano, Deborah Thompson, Robert J Macinnis, Mitul Shah, SEARCH Team, Douglas F Easton, Antonis C Antoniou
Jun 17, 2011
Generation and characterization of an Advillin-Cre driver mouse line.
Sandra Zurborg, Agnieszka Piszczek, Conception Martínez, Philip Hublitz, Mumna Al Banchaabouchi, Pedro Moreira, Emerald Perlas, Paul A Heppenstall
Aug 08, 2017
Progress in the somatosensory field has been restricted by the limited number of genetic tools available to study gene function in peripheral sensory neurons. Here we generated a Cre-driver mouse line that expresses...
Validating Operator Event Sequence Diagrams
NA Stanton, J Brown, KMA Revell, P Langdon, M Bradley, I Politis, L Skrypchuk, S Thompson, A Mouzakitis
Dec 15, 2021
Abstract: Predicting what drivers will do as vehicle control is handed over to them from automation is a relatively new challenge for the motor vehicle industry. Operator Event Sequence Diagrams (OESDs) offer a way of modeling...
Research on a Real-Time Driver Fatigue Detection Algorithm Based on Facial Video Sequences
The research on driver fatigue detection is of great significance to improve driving safety. This paper proposes a real-time comprehensive driver fatigue detection algorithm based on facial landmarks to improve the...
Modeling breast cancer progression to bone
Abstract: Background: Not all the mutations are equally important for the development of metastasis. What about their order? The survival of cancer cells from the primary tumour site to the secondary seeding sites depends on the...
Modeling breast cancer progression to bone
BACKGROUND: Not all the mutations are equally important for the development of metastasis. What about their order? The survival of cancer cells from the primary tumour site to the secondary seeding sites depends on the...
CYP2D6 gene variants
Jean E Abraham, Mel J Maranian, Kristy E Driver, Radka Platte, Bolot Kalmyrzaev, Caroline Baynes, Craig Luccarini, Mitul Shah, Susan Ingle, David Greenberg, Helena M Earl, Alison M Dunning, Paul DP Pharoah, Carlos Caldas
Jun 17, 2011
Adult Aged Antineoplastic Agents Hormonal Breast Neoplasms Chemotherapy Adjuvant Cohort Studies Cytochrome P-450 CYP2D6 Female Gene Frequency Genotype Humans Middle Aged Polymorphism Single Nucleotide Proportional Hazards Models Survival Analysis Tamoxifen Treatment Outcome United Kingdom Young Adult
N-over-N cascode push–pull modulator driver in 130 nm CMOS enabling 20 Gbit/s optical interconnection with Mach-Zehnder modulator
The N-over-N cascode push-pull modulator driver is demonstrated at 20 Gbit/s with IBM 130 nm technology. Electro-optical measurement of the modulator driver integrated with a Mach-Zehnder modulator (MZM) is also presented. This...
Development and field trial of a driver assistance system to encourage eco-driving in light commercial vehicle fleets
Driver training schemes and eco-driving techniques can reduce fuel
consumption by 10% but their effectiveness depends on the willingness of drivers to change their behaviour, and changes may be short lived. On board driver...
consumption by 10% but their effectiveness depends on the willingness of drivers to change their behaviour, and changes may be short lived. On board driver...
Development and field trial of a driver assistance system to encourage eco-driving in light commercial vehicle fleets
Driver training schemes and eco-driving techniques can reduce fuel
consumption by 10% but their effectiveness depends on the willingness of drivers to change their behaviour, and changes may be short lived. On board driver...
consumption by 10% but their effectiveness depends on the willingness of drivers to change their behaviour, and changes may be short lived. On board driver...
N-over-N cascode push–pull modulator driver in 130 nm CMOS enabling 20 Gbit/s optical interconnection with Mach-Zehnder modulator
The N-over-N cascode push-pull modulator driver is demonstrated at 20 Gbit/s with IBM 130 nm technology. Electro-optical measurement of the modulator driver integrated with a Mach-Zehnder modulator (MZM) is also presented. This...
Performing Locality and Identity
Lijun Zhang
Sep 21, 2016
The paper examines the fusion of narratives, time, space, and personal identity through ethnographic study of rickshaw driver’s performance in the context of “Hutong tour” as a form of urban tourism in Beijing, a cosmopolitan...
Published by: Association of Cambridge Studies
OESDs in an on-road study of semi-automated vehicle to human driver handovers
Abstract Design of appropriate interaction and human–machine interfaces for the handover of control between vehicle automation and human driver is critical to the success of automated vehicles....
NA Stanton, JW Brown, KMA Revell, J Kim, J Richardson, P Langdon, M Bradley, N Caber, L Skrypchuk, S Thompson
Apr 26, 2022
Virtual and Authentic Tennis: Similarities and Differences of Three Common Tennis Strokes
Kristy M. Noble
Jan 01, 0001
The purpose of this mixed-methods multi-phase study was to compare the similarities and differences of three common tennis strokes performed by National Collegiate Athletic Association Division I tennis players in an authentic...
Xbox Kinect virtual motion-based video gaming Active video gaming Education Health and Physical Education Sports Sciences
Published by: Winthrop University
Double Diffusion As a Driver of Turbulence in the Stratified Boundary Layer Beneath George VI Ice Shelf
Abstract: Warmer and more persistent intrusions of Circumpolar Deep Water (CDW) onto the West Antarctic Peninsula are a key driver of the recent increase in ice shelf mass loss. The relatively warm and salty CDW is thought to be...
PiggyBac mutagenesis and exome sequencing identify genetic driver landscapes and potential therapeutic targets of EGFR-mutant gliomas.
Imran Noorani, Jorge de la Rosa, Yoon Ha Choi, Alexander Strong, Hannes Ponstingl, MS Vijayabaskar, Jusung Lee, Eunmin Lee, Angela Richard-Londt, Mathias Friedrich, Federica Furlanetto, Rocio Fuente, Ruby Banerjee, Fengtang Yang, Frances Law, Colin Watts, Roland Rad, George Vassiliou, Jong Kyoung Kim, Thomas Santarius, Sebastian Brandner, Allan Bradley
Aug 14, 2020
Glioma is the most common intrinsic brain tumor and also occurs in the spinal cord. Activating EGFR mutations are common in IDH1 wild-type gliomas. However, the cooperative partners of EGFR driving gliomagenesis remain poorly...
Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance.
Daniel J Fazakerley, Rima Chaudhuri, Pengyi Yang, Ghassan J Maghzal, Kristen C Thomas, James R Krycer, Sean J Humphrey, Benjamin L Parker, Kelsey H Fisher-Wellman, Christopher C Meoli, Nolan J Hoffman, Ciana Diskin, James G Burchfield, Mark J Cowley, Warren Kaplan, Zora Modrusan, Ganesh Kolumam, Jean Yh Yang, Daniel L Chen, Dorit Samocha-Bonet, Jerry R Greenfield, Kyle L Hoehn, Roland Stocker, David E James
Aug 28, 2020
Insulin resistance in muscle, adipocytes and liver is a gateway to a number of metabolic diseases. Here, we show a selective deficiency in mitochondrial coenzyme Q (CoQ) in insulin-resistant adipose and muscle tissue. This...
Clonal somatic copy number altered driver events inform drug sensitivity in high-grade serous ovarian cancer
Abstract Chromosomal instability is a major challenge to patient stratification and targeted drug development for high-grade serous ovarian carcinoma (HGSOC). Here we show that somatic copy number...
Filipe Correia Martins, Dominique-Laurent Couturier, Ines de Santiago, Carolin Margarethe Sauer, Maria Vias, Mihaela Angelova, Deborah Sanders, Anna Piskorz, James Hall, Karen Hosking, Anumithra Amirthanayagam, Sabina Cosulich, Larissa Carnevalli, Barry Davies, Thomas BK Watkins, Ionut G Funingana, Helen Bolton, Krishnayan Haldar, John Latimer, Peter Baldwin, Robin Crawford, Matthew Eldridge, Bristi Basu, Mercedes Jimenez-Linan, Andrew W Mcpherson, Nicholas McGranahan, Kevin Litchfield, Sohrab P Shah, Iain McNeish, Carlos Caldas, Gerard Evan, Charles Swanton, James D Brenton
Oct 26, 2022
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