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Results: 160
Respiratory chain deficiency in nonmitochondrial disease.
Angela Pyle, Helen J Nightingale, Helen Griffin, Angela Abicht, Janbernd Kirschner, Ivo Baric, Mario Cuk, Konstantinos Douroudis, Lea Feder, Markus Kratz, Birgit Czermin, Stephanie Kleinle, Mauro Santibanez-Koref, Veronika Karcagi, Elke Holinski-Feder, Patrick F Chinnery, Rita Horvath
Mar 07, 2019
OBJECTIVE: In this study, we report 5 patients with heterogeneous phenotypes and biochemical evidence of respiratory chain (RC) deficiency; however, the molecular diagnosis is not mitochondrial disease. METHODS: The reported...
A study to determine whether cavitation occurs around dental ultrasonic scaling instruments
The aim of this investigation was to determine if cavitation occurred around dental ultrasonic scalers and to estimate the amount of cavitation occurring. Three styles of tip (3 x TFI-10, 3 x TFI-3, 3 x TFI-1) were used, in...
Classical Flt3L-dependent dendritic cells control immunity to protein vaccine
DCs are critical for initiating immunity. The current paradigm in vaccine biology is that DCs migrating from peripheral tissue and classical lymphoid-resident DCs (cDCs) cooperate in the draining LNs to initiate priming and...
Antigen Presentation cellular immunity Dendritic Cells langerhans cell ligand t lymphocyte activation
Published by: Rockefeller University
Flt3L dependence helps define an uncharacterized subset of murine cutaneous dendritic cells
Skin-derived dendritic cells (DCs) are potent antigen-presenting cells with critical roles in both adaptive immunity and tolerance to self. Skin DCs carry antigens and constitutively migrate to the skin-draining lymph nodes...
CD11b Antigen langerin dendritic cell chemokine receptors Flow Cytometry Microarray Analysis T lymphocyte
Published by: Rockefeller University
Mapping cavitation activity around dental ultrasonic tips
Objectives: Cavitation arising within the water around the oscillating ultrasonic scaler tip is an area that may lead to advances in enhancing biofilm removal. The aim of this study is to map the occurrence of cavitation around...
Using Global Red List Data to Inform Localised Research and Conservation Priorities—A Case Study in the Republic of Seychelles
Global Red List assessments are powerful tools for informing large-scale conservation decision-making processes, however, they can also be used to inform more localised research and conservation priorities. Here, a...
Robert W Bullock, Henriette MV Grimmel, Ellie E Moulinie, Dillys K Pouponeau, James SE Lea
Aug 21, 2022
Photosynthetic, respiratory and extracellular electron transport pathways in cyanobacteria.
A Statistical Study into the Number of Hours Students at Harrisburg University Spend on Social Media
The aim of the study is to examine the number of hours that Harrisburg University students spent on social media during their spare time. The purpose of the study is to raise awareness among students about the possible negative...
Published by: Harrisburg University of Science and Technology
A study to determine whether cavitation occurs around dental ultrasonic scaling instruments
The aim of this investigation was to determine if cavitation occurred around dental ultrasonic scalers and to estimate the amount of cavitation occurring. Three styles of tip (3 x TFI-10, 3 x TFI-3, 3 x TFI-1) were used, in...
Hope, Agency, and the Lived Experience of Violence
Lisa Arai, Ali Shaw, Gene Feder, Emma Howarth, Harriet MacMillan, Theresa HM Moore, Nicky Stanley, Alison Gregory
Jul 25, 2019
There is a large body of research on the impact of domestic violence and abuse (DVA) on children, mostly reporting survey data and focusing largely on psychological outcomes. Qualitative research on the views of children has the...
Mapping cavitation activity around dental ultrasonic tips
Objectives: Cavitation arising within the water around the oscillating ultrasonic scaler tip is an area that may lead to advances in enhancing biofilm removal. The aim of this study is to map the occurrence of cavitation around...
Remote Detection of Surge-Related Glacier Terminus Change across High Mountain Asia
High Mountain Asia (HMA) hosts the largest glacier concentration outside of polar regions. It is also distinct glaciologically as it forms one of two major surge clusters globally, and many glaciers there contradict the globally...
Characterization of TLR-induced inflammatory responses in COPD and control lung tissue explants
Purpose: Viruses are a common cause of exacerbations in chronic obstructive pulmonary disease (COPD). They activate toll-like receptors (TLRs) 3, 7, and 8, leading to a pro-inflammatory response. We have characterized the...
Characterization of TLR-induced inflammatory responses in COPD and control lung tissue explants
Purpose: Viruses are a common cause of exacerbations in chronic obstructive pulmonary disease (COPD). They activate toll-like receptors (TLRs) 3, 7, and 8, leading to a pro-inflammatory response. We have characterized the...
Effects of Multi-Shell Free Water Correction on Glioma Characterization.
Lea Starck, Fulvio Zaccagna, Ofer Pasternak, Ferdia Gallagher, Renate Grüner, Frank Riemer
Jan 05, 2022
Diffusion MRI is a useful tool to investigate the microstructure of brain tumors. However, the presence of fast diffusing isotropic signals originating from non-restricted edematous fluids, within and surrounding tumors, may...
BAP1/ASXL complex modulation regulates epithelial-mesenchymal transition during trophoblast differentiation and invasion.
Vicente Perez-Garcia, Georgia Lea, Pablo Lopez-Jimenez, Hanneke Okkenhaug, Graham J Burton, Ashley Moffett, Margherita Y Turco, Myriam Hemberger
Sep 05, 2021
Normal function of the placenta depends on the earliest developmental stages when trophoblast cells differentiate and invade into the endometrium to establish the definitive maternal-fetal interface. Previously, we identified...
CRISPR gene editing developmental biology Epithelial-Mesenchymal Transition human MOUSE Placenta Regenerative Medicine stem cell self-renewal Stem Cells trophoblast trophoblast invasion Animals Cell Differentiation Epithelial-Mesenchymal Transition Gene Expression Regulation Humans Mice Repressor Proteins Trophoblasts Tumor Suppressor Proteins Ubiquitin Thiolesterase
BAP1/ASXL complex modulation regulates epithelial-mesenchymal transition during trophoblast differentiation and invasion.
Vicente Perez-Garcia, Georgia Lea, Pablo Lopez-Jimenez, Hanneke Okkenhaug, Graham J Burton, Ashley Moffett, Margherita Y Turco, Myriam Hemberger
Jul 28, 2021
Normal function of the placenta depends on the earliest developmental stages when trophoblast cells differentiate and invade into the endometrium to establish the definitive maternal-fetal interface. Previously, we identified...
human Placenta trophoblast MOUSE trophoblast invasion developmental biology Stem Cells Epithelial-Mesenchymal Transition Regenerative Medicine stem cell self-renewal CRISPR gene editing
Published by: eLife
Stingray Habitat Use Is Dynamically Influenced by Temperature and Tides
Abiotic factors often have a large influence on the habitat use of animals in shallow marine environments. Specifically, tides may alter the physical and biological characteristics of an ecosystem while changes in...
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